Intrabiliary pressure changes produced by narcotic drugs and inhalation anesthetics in guinea pigs.

abstract：:The cold pressor test is often used to assess vasoconstrictive responses because it simulates the vasoconstrictive challenges commonly encountered in the clinical setting. With IRB approval, 12 healthy volunteers, aged 25--50 yr, underwent baseline plethysmographic monitoring on the finger and ear. The contralateral h...

journal_title：Anesthesia and analgesia

authors： Awad AA,Ghobashy MA,Ouda W,Stout RG,Silverman DG,Shelley KH

更新日期：2001-06-01 00:00:00

abstract：UNLABELLED:The adenosine triphosphate (ATP)-sensitive potassium channels (K(+)-ATP channels) are activated by decreases in intracellular ATP and help to match blood flow to tissue needs. Such metabolism-flow coupling occurs predominantly in the smallest arterioles measuring 50 microm or less in diameter. Previous studi...

journal_title：Anesthesia and analgesia

authors： Park KW,Dai HB,Comunale ME,Gopal A,Sellke FW

更新日期：2000-07-01 00:00:00

abstract：UNLABELLED:Children undergoing placement of bilateral myringotomy tubes (BMT) often exhibit pain-related behavior (agitation) in the postanesthesia care unit. We compared the emergence and recovery profiles of pediatric patients who received sevoflurane with or without supplementary intranasal fentanyl for BMT surgery....

journal_title：Anesthesia and analgesia

authors： Finkel JC,Cohen IT,Hannallah RS,Patel KM,Kim MS,Hummer KA,Choi SS,Pena M,Schreiber SB,Zalzal G

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:In this study, we compared the effect of light sedation with remifentanil versus propofol on intracranial (ICP) and cerebral perfusion pressure (CPP) of patients undergoing stereotactic brain tumor biopsy under regional anesthesia. METHODS:This was a prospective, open-label, randomized, and controlled study...

journal_title：Anesthesia and analgesia

authors： Girard F,Moumdjian R,Boudreault D,Chouinard P,Bouthilier A,Ruel M

更新日期：2009-07-01 00:00:00

abstract：UNLABELLED:Intraoperative transesophageal echocardiography (TEE) is frequently used in children with congenital heart disease (CHD). Although transnasal TEE is being used in various settings in the adult population, there are no descriptions of its use intraoperatively in patients with CHD. This report describes the su...

journal_title：Anesthesia and analgesia

authors： Aronson LA

更新日期：2003-12-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to determine if rates of telemetry events differ between patients whose monitoring is appropriately "indicated" versus "not indicated" by systematically applying rigorous criteria for appropriateness of electrocardiogram (ECG) telemetry usage. We performed a retrospective cohort...

journal_title：Anesthesia and analgesia

authors： Curry JP,Hanson CW 3rd,Russell MW,Hanna C,Devine G,Ochroch EA

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The cellular mechanisms underlying the sedative effect of general anesthetics are not completely understood. Accumulating evidence indicates that the ventrolateral preoptic area (VLPO) of the hypothalamus plays a critical role. The VLPO contains 2 major types of neurons, the noradrenalin-inhibited GABAergic ...

journal_title：Anesthesia and analgesia

authors： Liu YW,Zuo W,Ye JH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:I.v. injection of propofol during anesthetic induction induces pain. Ketamine has been shown to reduce injection pain. In this study, we established the optimal dose of ketamine to prevent the pain of injection with propofol. METHODS:Two hundred forty patients presenting for elective surgery were randomly a...

journal_title：Anesthesia and analgesia

authors： Koo SW,Cho SJ,Kim YK,Ham KD,Hwang JH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal of residual neuromuscular blockade. We tested the hypothesis that sugammadex would provide for a more rapid reversal of a moderately profound residual rocuronium-induced blockade than the com...

journal_title：Anesthesia and analgesia

authors： Sacan O,White PF,Tufanogullari B,Klein K

更新日期：2007-03-01 00:00:00

abstract：:Hepatic blood flow and the oxygen supply/uptake relation were studied in 19 miniature pigs using labeled microspheres. Changes in hepatic arterial blood flow and portal blood flow, as well as total hepatic blood flow during halothane anesthesia were more closely associated with changes in mean arterial pressure (MAP) ...

journal_title：Anesthesia and analgesia

authors： Gelman S,Dillard E,Bradley EL Jr

更新日期：1987-10-01 00:00:00

abstract：:The aim of this study was to correlate pupillary diameter with respiratory depression for 20 hr after epidural administration of morphine or buprenorphine. Pupillary diameter and the ventilatory sensitivity to CO2 were measured in six healthy volunteers at various times (0, 0.5, 1, 2, 3, 4, 6, 8, 10, 12, and 20 hr) in...

journal_title：Anesthesia and analgesia

authors： Ravnborg M,Jensen FM,Jensen NH,Holk IK

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Many clinical pain states that are difficult to treat share a common feature of sensitization of nociceptive pathways. Drugs that could normalize hyperexcitable neural activity (e.g., antiepileptic drugs) may be useful in relieving these pain states. Eslicarbazepine acetate (ESL) is a novel antiepileptic dru...

journal_title：Anesthesia and analgesia

authors： Tomić MA,Pecikoza UB,Micov AM,Stepanović-Petrović RM

更新日期：2015-12-01 00:00:00

abstract：:Combinations of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids are widespread in the management of pain, allowing better analgesia with reduced side effects. Cannabinoids are promising analgesic drugs that have pharmacological properties similar to those of opioids. However, the beneficial effects of cannabi...

journal_title：Anesthesia and analgesia

authors： Ulugöl A,Ozyigit F,Yesilyurt O,Dogrul A

更新日期：2006-02-01 00:00:00

abstract：:Selective segmental nerve blocks with local anesthetics are applied for diagnostic purposes in patients with chronic back pain to determine the segmental level of the pain. We performed this study to establish myotomal motor effects after L4 spinal nerve blocks by lidocaine and ropivacaine and to evaluate the relation...

journal_title：Anesthesia and analgesia

authors： Wolff AP,Wilder Smith OH,Crul BJ,van de Heijden MP,Groen GJ

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:QT interval prolongation is associated with torsades des pointes (TdP), but is a poor predictor of drug torsadogenicity. Susceptibility to TdP arises from increased transmural dispersion of repolarization (TDR) across the myocardial wall, rather than QT interval prolongation per se. TDR can be measured on th...

journal_title：Anesthesia and analgesia

authors： Whyte SD,Sanatani S,Lim J,Booker PD

更新日期：2007-02-01 00:00:00

abstract：UNLABELLED:The site for needle insertion in femoral nerve block varies significantly among various descriptions of the technique. To determine the site with the highest likelihood of needle-femoral nerve contact, femoral nerve block was simulated in a human cadaver model (17 femoral triangles from 9 adult cadavers). Fo...

journal_title：Anesthesia and analgesia

authors： Vloka JD,Hadzić A,Drobnik L,Ernest A,Reiss W,Thys DM

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Transesophageal echocardiography (TEE) is a valuable monitor for patients undergoing cardiac and noncardiac surgery as it allows for evaluation of cardiovascular compromise in the perioperative period. It is challenging for anesthesiology residents and medical students to learn to use and interpret TEE in th...

journal_title：Anesthesia and analgesia

authors： Kleiman AM,Forkin KT,Bechtel AJ,Collins SR,Ma JZ,Nemergut EC,Huffmyer JL

更新日期：2017-05-01 00:00:00

abstract：UNLABELLED:We compared the laryngeal mask airway ProSeal (PLMA) and the laryngeal tube airway (LTA), two new extraglottic airway devices, with respect to: 1) insertion success rates and times, 2) efficacy of seal, 3) ventilatory variables during pressure-controlled ventilation, 4) tidal volume in different head/neck po...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Keller C,Brimacombe L

更新日期：2002-09-01 00:00:00

abstract：:A pharmacokinetic evaluation of bupivacaine was carried out after intercostal nerve blocks performed on 28 occasions in 27 children varying in age from 3 months to 16 yr. Bupivacaine HCl, 0.5%, with epinephrine 1:200,000 was employed. Doses of 2 mg/kg, 3 mg/kg, and 4 mg/kg resulted in peak whole blood arterial bupivac...

journal_title：Anesthesia and analgesia

authors： Rothstein P,Arthur GR,Feldman HS,Kopf GS,Covino BG

更新日期：1986-06-01 00:00:00

abstract：UNLABELLED:Rapacuronium (Org 9487) is a rapid-onset and short- to intermediate-acting muscle relaxant. Its 3-desacetyl metabolite, Org 9488, also exerts neuromuscular-blocking activity that may become apparent after prolonged maintenance of relaxation with rapacuronium. In this study, the pharmacokinetic behavior (n = ...

journal_title：Anesthesia and analgesia

authors： Schiere S,Proost JH,Schuringa M,Wierda JM

更新日期：1999-03-01 00:00:00

abstract：:Alfentanil causes cardiac stimulation or depression in intact animals and in clinical practice; there is no information concerning its direct effects on the heart. Therefore, we studied the effects of alfentanil on isolated cardiac tissues from young adult rabbits. The right atrium with sinoatrial node (SA node) was b...

journal_title：Anesthesia and analgesia

authors： Zhang CC,Su JY,Calkins D

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:There is a pronounced learning curve for the technique of ultrasound-guided regional anesthesia. Practicing with a simulator model has been shown to speed the acquisition of these skills for various ultrasound-guided procedures. However, commercial models for ultrasound-guided regional anesthesia may be too ...

journal_title：Anesthesia and analgesia

authors： Liu Y,Glass NL,Power RW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle calcium regulation associated primarily, but not exclusively, with mutations in the skeletal muscle ryanodine receptor. Associated environmental factors, however, may also be important for expression of the syndrome. METHODS AND RE...

journal_title：Anesthesia and analgesia

authors： Capacchione JF,Radimer MC,Sagel JS,Kraus GP,Sambuughin N,Muldoon SM

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:In this prospective investigation, we evaluated the efficacy and accuracy of transcutaneous monitoring of CO2 (TC-CO2) in infants and children after cardiothoracic surgery. Cardiothoracic surgery patients whose ETCO2 and arterial CO2 values did not correlate (gradient > or = 5 mm Hg) during the first postope...

journal_title：Anesthesia and analgesia

authors： Tobias JD,Wilson WR Jr,Meyer DJ

更新日期：1999-03-01 00:00:00

abstract：UNLABELLED:There is concern that the environment in which consent for anesthesia research is sought may be coercive. We therefore designed this study to determine the factors that parents consider in consenting to their child's participation in clinical anesthesia research. The study sample consisted of 246 parents who...

journal_title：Anesthesia and analgesia

authors： Tait AR,Voepel-Lewis T,Siewert M,Malviya S

更新日期：1998-01-01 00:00:00

abstract：UNLABELLED:Suppression of nitric oxide (NO) production alters the toxicity of cocaine and bupivacaine. We undertook this study to determine whether the systemic toxicity of two other local anesthetics that differ in antiarrhythmic activity, plasma clearance, and biotransformation are similarly affected by nitric oxide ...

journal_title：Anesthesia and analgesia

authors： Heavner JE,Shi B,Pitkänen M

更新日期：1999-04-01 00:00:00

abstract：:We investigated the usefulness of peripheral flow index (PFI) measurement using a standard pulse oximetry digit probe for early prediction of successful regional blocks. Sixty-six patients scheduled for limb surgery underwent either axillary or sciatic block using a nerve stimulator technique with mepivacaine 1.5%. PF...

journal_title：Anesthesia and analgesia

authors： Galvin EM,Niehof S,Verbrugge SJ,Maissan I,Jahn A,Klein J,van Bommel J

更新日期：2006-07-01 00:00:00

abstract：UNLABELLED:Studies demonstrate lasting cognitive impairment in elderly persons after anesthesia and surgery. We tested the hypothesis that general anesthesia contributes to this cognitive impairment. Six- and 18-mo-old Fischer 344 rats were trained in a 12-arm radial arm maze and were then randomized to anesthesia for ...

journal_title：Anesthesia and analgesia

authors： Culley DJ,Baxter M,Yukhananov R,Crosby G

更新日期：2003-04-01 00:00:00

abstract：:The purpose of this study was to characterize the pharmacodynamics and pharmacokinetics of three concentrations of the new long-acting amide local anesthetic, ropivacaine, given epidurally in 15 physical status ASA I or II patients for elective lower-extremity orthopedic procedures using a nonrandomized open-label des...

journal_title：Anesthesia and analgesia

authors： Katz JA,Bridenbaugh PO,Knarr DC,Helton SH,Denson DD

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Although local anesthetics (LAs) are generally accepted as being safe, incidental neuronal damage has been reported for all LAs in humans. Therefore, in this study, we compared the dose corresponding to 50% cell lethality (LD50) of articaine, lidocaine, mepivacaine, bupivacaine, prilocaine, and ropivacaine i...

journal_title：Anesthesia and analgesia

authors： Malet A,Faure MO,Deletage N,Pereira B,Haas J,Lambert G

更新日期：2015-03-01 00:00:00