Management of suspected malignant hyperpyrexia in an infant.

abstract：UNLABELLED:We investigated the effects of sevoflurane and hyperventilation on intraoperative electrocorticogram (ECoG) spike activity in 13 patients with intractable epilepsy. Grid electrodes were placed on the brain surface and ECoG was recorded under the following conditions: 1) 0.5 minimal alveolar anesthetic concen...

journal_title：Anesthesia and analgesia

authors： Kurita N,Kawaguchi M,Hoshida T,Nakase H,Sakaki T,Furuya H

更新日期：2005-08-01 00:00:00

abstract：:Under halothane anesthesia five dogs were prepared with both hindlimbs isolated from the systemic circulation to allow intermittent placement on extracorporeal perfusion at constant flow. One limb of each dog was surgically denervated. In this relatively anesthetic-free preparation, graded equivalent doses of alfentan...

journal_title：Anesthesia and analgesia

authors： White DA,Reitan JA,Kien ND,Thorup SJ

更新日期：1990-07-01 00:00:00

abstract：:We considered the allocation of operating room (OR) time at facilities where the strategic decision had been made to increase the number of ORs. Allocation occurs in two stages: a long-term tactical stage followed by short-term operational stage. Tactical decisions, approximately 1 yr in advance, determine what specia...

journal_title：Anesthesia and analgesia

authors： Dexter F,Ledolter J,Wachtel RE

更新日期：2005-05-01 00:00:00

abstract：IMPLICATIONS:Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain. ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Azevedo MI

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) patients typically receive either tubeless anesthesia or general endotracheal anesthesia (GETA). Patients receiving propofol-based total intravenous anesthesia (TIVA) are at higher risk of sedation-related adverse events (SRAEs) than patients receiving GE...

journal_title：Anesthesia and analgesia

authors： Hagan KB,Carlson R,Arnold B,Nguyen L,Lee J,Weston B,Hernandez M,Feng L,Syed T,Hagberg CA

更新日期：2020-11-01 00:00:00

abstract：:We assessed the effect of small clonidine doses on anxiolysis, analgesia, and hemodynamic stability in patients undergoing abdominal hysterectomy. A total of 61 patients, ASA status I-II, were randomly assigned to receive either oral clonidine 100 microg (n = 29) or placebo (n = 32) before surgery and 24 h after surge...

journal_title：Anesthesia and analgesia

authors： Hidalgo MP,Auzani JA,Rumpel LC,Moreira NL Jr,Cursino AW,Caumo W

更新日期：2005-03-01 00:00:00

abstract：:Initial, but not subsequent, inhalation of 8% desflurane produces transient sympathetic stimulation. We hypothesized that initial but not subsequent increases should produce pupil dilation, and that N2O, fentanyl, and clonidine, but not esmolol, should blunt the response. In 10 volunteers, we maintained anesthesia wit...

journal_title：Anesthesia and analgesia

authors： Daniel M,Larson MD,Eger EI 2nd,Noorani M,Weiskopf RB

更新日期：1995-08-01 00:00:00

abstract：:The effects of midazolam on atrial rate and contractile force in the isolated canine atrium perfused with donor blood were investigated. When midazolam in a dose range of 100-1000 micrograms was injected directly into the sinus node artery of the isolated atrium, biphasic (negative followed by positive) chronotropic a...

journal_title：Anesthesia and analgesia

authors： Saegusa K,Furukawa Y,Ogiwara Y,Takeda M,Chiba S

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:I.v. injection of propofol during anesthetic induction induces pain. Ketamine has been shown to reduce injection pain. In this study, we established the optimal dose of ketamine to prevent the pain of injection with propofol. METHODS:Two hundred forty patients presenting for elective surgery were randomly a...

journal_title：Anesthesia and analgesia

authors： Koo SW,Cho SJ,Kim YK,Ham KD,Hwang JH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:High-quality shared decision-making for patients undergoing elective surgical procedures includes eliciting patient goals and treatment preferences. This is particularly important, should complications occur and life-sustaining therapies be considered. Our objective was to determine the preoperative care pre...

journal_title：Anesthesia and analgesia

authors： Udelsman BV,Govea N,Cooper Z,Chang DC,Bader A,Meyer MJ

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The spinal cord is an important site where volatile anesthetics decrease sensation and produce immobility. Beyond this knowledge, our understanding of a site of anesthetic action is limited. Previous evidence suggests that dorsal horn neurons with ascending projections may be more susceptible to depression b...

journal_title：Anesthesia and analgesia

authors： Barter LS,Mark LO,Jinks SL,Carstens EE,Antognini JF

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Hyperkalemia poses serious hazards to patients undergoing orthotopic liver transplantation (OLT), and its predictors have not been thoroughly examined. METHODS:We retrospectively studied 1124 consecutive adult patients who underwent OLT. Hyperkalemia was defined as serum K+ > or =5.5 mmol/L. A total of 47 r...

journal_title：Anesthesia and analgesia

authors： Xia VW,Ghobrial RM,Du B,Chen T,Hu KQ,Hiatt JR,Busuttil RW,Steadman RH

更新日期：2007-09-01 00:00:00

abstract：:The effects of enflurane on responses of isolated canine mesenteric arteries and veins to transmural nerve stimulation and to exogenously administered norepinephrine (a mixed alpha 1- and alpha 2-adrenoceptor agonist), phenylephrine (a selective alpha 1-adrenoceptor agonist), and tyramine were studied. The contractile...

journal_title：Anesthesia and analgesia

authors： Kobayashi Y,Yoshida K,Noguchi M,Wakasugi Y,Ito H,Okabe E

更新日期：1990-05-01 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Endotracheal tubes (ETTs) are commonly secured with tape to prevent undesirable tube migration. Many methods of taping have been described, although little has been published comparing various methods of taping to one another. In this study, we evaluated several methods for securing ETTs with tape. We hypoth...

journal_title：Anesthesia and analgesia

authors： Matchett G,Yang JH,Sripathi NR,Simpkins L,Ruikar K,Minhajuddin A,Whitten CW

更新日期：2020-08-01 00:00:00

abstract：:The purpose of this study was to compare the perioperative effects of the intramuscular (i.m.) alpha 2 agonist, dexmedetomidine (DEX), and midazolam (MID) premedication. The study comprised 192 women (64 per group) scheduled for abdominal hysterectomy. The doses of the study drugs were chosen to obtain equal sedative ...

journal_title：Anesthesia and analgesia

authors： Erkola O,Korttila K,Aho M,Haasio J,Aantaa R,Kallio A

更新日期：1994-10-01 00:00:00

abstract：:Neurotoxicity has been reported with tricyclic antidepressants (TCAs) used as local anesthetics. We examined the hypothesis that TCAs cause tissue injury, particularly myotoxicity, as occurs with many local anesthetics. Animals were given sciatic nerve injections with 0-80 mM doxepin, amitriptyline, or bupivacaine (1....

journal_title：Anesthesia and analgesia

authors： Barnet CS,Louis DN,Kohane DS

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:β3 containing γ-aminobutyric acid type A receptors (GABA(A)-Rs) mediate behavioral end points of IV anesthetics such as immobility and hypnosis. A knockout mouse with targeted forebrain deletion of the β3 subunit of the GABA(A)-R shows reduced sensitivity to the hypnotic effect of etomidate, as measured by t...

journal_title：Anesthesia and analgesia

authors： Rau V,Oh I,Liao M,Bodarky C,Fanselow MS,Homanics GE,Sonner JM,Eger EI 2nd

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00

abstract：:Tracheal injuries, independent of their origin, may be life-threatening. Surgical repair is regarded as the treatment of choice but has not been compared with other approaches. We hypothesized that defects bridgeable by an artificial airway may enable conservative treatment. We report on five patients with tracheal in...

journal_title：Anesthesia and analgesia

authors： Beiderlinden M,Adamzik M,Peters J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Inhalation agents are being used in place of intravenous agents to provide sedation in some intensive care units. We performed a systematic review and meta-analysis of prospective randomized controlled trials, which compared the use of volatile agents versus intravenous midazolam or propofol in critical care...

journal_title：Anesthesia and analgesia

authors： Jerath A,Panckhurst J,Parotto M,Lightfoot N,Wasowicz M,Ferguson ND,Steel A,Beattie WS

更新日期：2017-04-01 00:00:00

abstract：UNLABELLED:We compared the ketoprofen-propacetamol combination relative to propacetamol alone in thyroid and parathyroid surgery in terms of postoperative analgesic efficacy, bleeding, and incidence of nausea and vomiting to determine whether ketoprofen results in any benefit in this type of surgery. Patients were dist...

journal_title：Anesthesia and analgesia

authors： Basto ER,Waintrop C,Mourey FD,Landru JP,Eurin BG,Jacob LP

更新日期：2001-04-01 00:00:00

abstract：:We have recently reported a chronic allodynialike symptom in rats after ischemic spinal cord injury. This pain-related behavior is resistant to a number of pharmacologic treatments, including morphine, clonidine, carbamazepine, baclofen, and muscimol. In the present report, we present evidence indicating that systemic...

journal_title：Anesthesia and analgesia

authors： Xu XJ,Hao JX,Seiger A,Arnér S,Lindblom U,Wiesenfeld-Hallin Z

更新日期：1992-05-01 00:00:00

abstract：UNLABELLED:Postoperative pain has been an important limiting factor for ambulatory laparoscopic cholecystectomy. We anesthetized 40 ASA physical status I-II patients using propofol for the induction and sevoflurane in oxygen and air for the maintenance of anesthesia. At the end of the anesthesia, the patients were rand...

journal_title：Anesthesia and analgesia

authors： Gupta A,Thörn SE,Axelsson K,Larsson LG,Agren G,Holmström B,Rawal N

更新日期：2002-08-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：UNLABELLED:Calcium-sensitizing drugs, such as levosimendan, are a novel class of drug therapy for heart failure. We investigated the hypothesis that levosimendan is a pulmonary vasodepressor mediated through inhibition of phosphodiesterase, adenosine triphosphate (ATP)-dependent potassium channels, or both. We investig...

journal_title：Anesthesia and analgesia

authors： De Witt BJ,Ibrahim IN,Bayer E,Fields AM,Richards TA,Banister RE,Kaye AD

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Previous modeling of the kinetics of uptake and elimination of anesthetic drugs from the site of action has used measures derived from the electroencephalogram. Such measures lag the current brain activity because of the time needed to acquire a signal sample and derive the measure. With a direct measure of ...

journal_title：Anesthesia and analgesia

authors： Drummond GB,Bleach L,Thomson AJ,Kennedy RR

更新日期：2012-09-01 00:00:00

abstract：:Controversy exists concerning the choice of anesthetic technic for elective cesarean section. Several maternal and newborn parameters were compared during general anesthesia (GA) and lumbar epidural analgesia (LEA). High inspired maternal O2 levels were achieved with both technics. Vigorous, well-oxygenated infants wi...

journal_title：Anesthesia and analgesia

authors： James FM 3rd,Crawford JS,Hopkinson R,Davies P,Naiem H

更新日期：1977-03-01 00:00:00

abstract：:The dose-dependent effects of nitrous oxide on thymidine and methionine syntheses were investigated in pregnant rats. Female Sprague-Dawley rats were exposed on day 9 of gestation to 0.75%, 7.5%, or 75% nitrous oxide for 24 h. Immediately and 72 h after exposure, a deoxyuridine-suppression test was performed on matern...

journal_title：Anesthesia and analgesia

authors： Baden JM,Rice SA,Serra M,Kelley M,Mazze R

更新日期：1983-08-01 00:00:00

abstract：:Computer-based measuring of the level of sedation and hypnosis is difficult and has proven to be challenging. The electroencephalogram (EEG) has been proposed as a potential method. Response entropy (RE) and state entropy (SE) are multifactor, dimensionless parameters of a new technology of EEG monitoring, and we inve...

journal_title：Anesthesia and analgesia

authors： Litscher G

更新日期：2006-06-01 00:00:00