Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.

abstract：BACKGROUND:Postoperative delirium is a major debilitating complication for patients and is associated with poor outcomes. Previous studies have suggested that excessive general anesthesia may lead to postoperative delirium. Electroencephalography (EEG)-based monitors have been administered in clinical practice in an at...

journal_title：Anesthesia and analgesia

authors： Sun Y,Ye F,Wang J,Ai P,Wei C,Wu A,Xie W

更新日期：2020-09-01 00:00:00

abstract：:Bispectral Index Scale (BIS)-guided closed-loop delivery of anesthetics has been extensively studied. We performed a meta-analysis of all the randomized clinical trials comparing efficacy and performance between BIS-guided closed-loop delivery and manually controlled administration of total IV anesthesia. Scopus, PubM...

journal_title：Anesthesia and analgesia

authors： Pasin L,Nardelli P,Pintaudi M,Greco M,Zambon M,Cabrini L,Zangrillo A

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Implementing Bayesian methods in a model-based closed-loop system requires the integration of a standard response model with a patient-specific response model. This process makes use of specific modeling weights, called Bayesian variances, which determine how the specific model can deviate from the standard ...

journal_title：Anesthesia and analgesia

authors： De Smet T,Struys MM,Greenwald S,Mortier EP,Shafer SL

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Music reduces stress responses in awake subjects. However, there remains controversy about the role of music or therapeutic suggestions during general anesthesia and postoperative recovery. We thus tested the hypothesis that intraoperative exposure to soothing music reduces the end-tidal concentration of sev...

journal_title：Anesthesia and analgesia

authors： Szmuk P,Aroyo N,Ezri T,Muzikant G,Weisenberg M,Sessler DI

更新日期：2008-07-01 00:00:00

abstract：:The effects of midazolam on atrial rate and contractile force in the isolated canine atrium perfused with donor blood were investigated. When midazolam in a dose range of 100-1000 micrograms was injected directly into the sinus node artery of the isolated atrium, biphasic (negative followed by positive) chronotropic a...

journal_title：Anesthesia and analgesia

authors： Saegusa K,Furukawa Y,Ogiwara Y,Takeda M,Chiba S

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. METH...

journal_title：Anesthesia and analgesia

authors： Liu N,Chazot T,Hamada S,Landais A,Boichut N,Dussaussoy C,Trillat B,Beydon L,Samain E,Sessler DI,Fischler M

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As part of the Thai Anesthesia Incidents Study of anesthetic adverse outcomes, we evaluated the incidence and factors related to cardiac arrest during spinal anesthesia. METHODS:During a 12-mo period (March 1, 2003, to February 28, 2004), a prospective, multicenter registry of patients receiv...

journal_title：Anesthesia and analgesia

authors： Charuluxananan S,Thienthong S,Rungreungvanich M,Chanchayanon T,Chinachoti T,Kyokong O,Punjasawadwong Y

更新日期：2008-11-01 00:00:00

abstract：:We have developed computer software to store data on all surgical and obstetrical anesthetics administered by our department. The computer system provides information for monitoring the residency training program, department and operating room management, professional fee billing, and research. It imposes little addit...

journal_title：Anesthesia and analgesia

authors： Bashein G,Barna CR

更新日期：1985-04-01 00:00:00

abstract：:The effect of enflurane anesthesia on bronchomotor tone was studied in 15 dogs, using isolated tracheal segments in situ. In six animals, the changes of tracheal tension in response to changing enflurane concentration were continuously measured while keeping tidal volume, respiratory frequency, and end-tidal PCO2 cons...

journal_title：Anesthesia and analgesia

authors： Kochi T,Hagiya M,Mizuguchi T

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Medical procedures often evoke pain and anxiety in pediatric patients. Virtual reality (VR) is a relatively new intervention that can be used to provide distraction during, or to prepare patients for, medical procedures. This meta-analysis is the first to collate evidence on the effectiveness of VR on reduci...

journal_title：Anesthesia and analgesia

authors： Eijlers R,Utens EMWJ,Staals LM,de Nijs PFA,Berghmans JM,Wijnen RMH,Hillegers MHJ,Dierckx B,Legerstee JS

更新日期：2019-11-01 00:00:00

abstract：:Combinations of benzodiazepines (midazolam and diazepam) with barbiturates (pentobarbital and phenobarbital) exhibit synergistic (supra-additive) hypnotic interactions in rats. Because both benzodiazepines and barbiturates interact with the gamma-aminobutyric acidA (GABAA) receptor complex, we have tested the hypothes...

journal_title：Anesthesia and analgesia

authors： DeLorey TM,Kissin I,Brown P,Brown GB

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Patients with muscular dystrophy have been reported to experience a variety of life-threatening complications during and after general anesthesia. We performed a systematic analysis to define the spectrum of anesthetic-related complications in patients with muscular dystrophy, with an emphasis on malignant h...

journal_title：Anesthesia and analgesia

authors： Gurnaney H,Brown A,Litman RS

更新日期：2009-10-01 00:00:00

abstract：:Ten volunteers were studied during six stages of propofol sedation, namely awake (no propofol), light sedation (small dose of propofol), deep sedation (large dose), deep sedation with stimulation of the ulnar nerve, then light sedation again (small dose), and awake (recovery). Light and deep sedation were defined in t...

journal_title：Anesthesia and analgesia

authors： Andrade J,Sapsford DJ,Jeevaratnum D,Pickworth AJ,Jones JG

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Current guidelines from the American College of Obstetricians and Gynecologists recommend antibiotic prophylaxis for cesarean delivery immediately before incision. The purpose of this study was to measure and describe correlates of adherence to these guidelines in a sample of United States anesthesiologists....

journal_title：Anesthesia and analgesia

authors： Raghunathan K,Connelly NR,Friderici J,Naglieri-Prescod D,Joyce R,Prasanna P,Ponnusamy N

更新日期：2013-03-01 00:00:00

abstract：:The aim of this study was to determine the significance of new electrocardiographic (ECG) ST elevation during coronary artery bypass surgery. Multilead ECGs were recorded intraoperatively approximately every 3 min on 105 patients. Cases of new ST elevation were divided into ischemic and those considered to be due to n...

journal_title：Anesthesia and analgesia

authors： Jain U,Wallis DE,Moran JF

更新日期：1994-04-01 00:00:00

abstract：:The decrease of cardiac index observed during portal triad clamping (PTC) with and without pneumoperitoneum has been studied only with right heart catheterization. To better understand this decrease of cardiac index, we investigated the balance between the adequacy of preload and the ability of the heart to pump again...

journal_title：Anesthesia and analgesia

authors： Decailliot F,Streich B,Heurtematte Y,Duvaldestin P,Cherqui D,Stéphan F

更新日期：2005-03-01 00:00:00

abstract：:In a randomized, double-blind, placebo-controlled trial, we evaluated the use of preoperative local anesthesia with regard to postoperative pain. Before surgery in 66 patients scheduled for cholecystectomy, the abdominal wall along the proposed line of incision was infiltrated with 70 mL of 0.25% ropivacaine, 70 mL of...

journal_title：Anesthesia and analgesia

authors： Johansson B,Glise H,Hallerbäck B,Dalman P,Kristoffersson A

更新日期：1994-02-01 00:00:00

abstract：:We compared laryngeal aperture (LA) exposure and endotracheal intubation difficulty scale (IDS) scores between balloon-assisted and conventional laryngoscopy. Thirty-two anesthetized and paralyzed elective surgery patients underwent laryngoscopy with a standard number 4 and a modified number 4 curved blade carrying a ...

journal_title：Anesthesia and analgesia

authors： Mentzelopoulos SD,Romana CN,Corolanoglou DS,Tzoufi MJ,Karamichali EA

更新日期：2000-12-01 00:00:00

abstract：:Patients with frailty experience substantial physical and emotional distress related to their condition and face increased morbidity and mortality compared with their nonfrail peers. Palliative care is an interdisciplinary medical specialty focused on improving quality of life for patients with serious illness, includ...

journal_title：Anesthesia and analgesia

authors： Crooms RC,Gelfman LP

更新日期：2020-06-01 00:00:00

abstract：:Hemiplegic migraine is a condition associated with vascular alteration of the central nervous system and transient neurologic deficits. Permanent morphine-induced motor dysfunction has been reported after spinal ischemia. We report a persisting central neurological deficit after single-dose spinal administration of 40...

journal_title：Anesthesia and analgesia

authors： Lentschener C,Dousset B,Zuber M,Ozier Y

更新日期：2009-11-01 00:00:00

abstract：:Arginine vasopressin (AVP) is a potent supplementary vasopressor in advanced vasodilatory shock, but decreases in platelet count have been reported during AVP therapy. In this study we evaluated the effects of AVP infusion on the coagulation system in advanced vasodilatory shock when compared to norepinephrine (NE) in...

journal_title：Anesthesia and analgesia

authors： Dünser MW,Fries DR,Schobersberger W,Ulmer H,Wenzel V,Friesenecker B,Hasibeder WR,Mayr AJ

更新日期：2004-07-01 00:00:00

abstract：:A well secured endotracheal tube is very essential for the safe conduct of anesthesia. In maxillofacial surgeries, providing secure fixation of the nasotracheal tube has always been a problem. We have used an infant feeding tube that goes around the nasal septum for the fixation of the nasal endotracheal tube. This me...

journal_title：Anesthesia and analgesia

authors： Bhat VR,Venkateshwaran G

更新日期：2004-11-01 00:00:00

abstract：:The effect of laparoscopy on cardiac function is controversial. We hypothesized that cardiac dysfunction related to increased afterload could be predominant in patients undergoing elective abdominal aortic repair. To test this hypothesis, we conducted a transesophageal echocardiographic study in 15 patients during lap...

journal_title：Anesthesia and analgesia

authors： Alfonsi P,Vieillard-Baron A,Coggia M,Guignard B,Goeau-Brissonniere O,Jardin F,Chauvin M

更新日期：2006-05-01 00:00:00

abstract：UNLABELLED:Patients undergoing vascular surgery have a high risk of suffering major postoperative cardiac events. Preoperative myocardial ischemia as detected by Holter monitoring identifies a high-risk subgroup whose postoperative ischemia, similarly detected, seems to herald major cardiac events. In this study, we de...

journal_title：Anesthesia and analgesia

authors： Raby KE,Brull SJ,Timimi F,Akhtar S,Rosenbaum S,Naimi C,Whittemore AD

更新日期：1999-03-01 00:00:00

abstract：UNLABELLED:To investigate the risk factors for postoperative neurological deterioration in patients with moyamoya disease, we retrospectively reviewed the perioperative course of 368 cases of revascularization surgery in 216 patients with this disease. Risk factors anecdotally associated with postoperative ischemic eve...

journal_title：Anesthesia and analgesia

authors： Sakamoto T,Kawaguchi M,Kurehara K,Kitaguchi K,Furuya H,Karasawa J

更新日期：1997-11-01 00:00:00

abstract：UNLABELLED:We studied the effects of spinal cord stimulation (SCS) on postherpetic neuralgia (PHN). Data of 28 patients were prospectively investigated over a median period of 29 (quartiles 9--39) mo. In addition, four patients with acute herpes zoster (HZ) pain were studied simultaneously. After intractable pain for m...

journal_title：Anesthesia and analgesia

authors： Harke H,Gretenkort P,Ladleif HU,Koester P,Rahman S

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Preoperative risk stratification is a critical element in assessing the risks and benefits of surgery. Prior work has demonstrated that intra-abdominal general surgery patients can be classified based on their comorbidities and risk factors using latent class analysis (LCA), a model-based clustering techniqu...

journal_title：Anesthesia and analgesia

authors： Kim M,Wall MM,Li G

更新日期：2018-03-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to investigate whether propofol protects rat hepatocyte suspensions against an oxidant attack by a free radical generator 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH). Rat hepatocyte suspensions (2 x 10(6) cells/mL) were prepared using Seglen's collagenase perfusion tec...

journal_title：Anesthesia and analgesia

authors： Navapurkar VU,Skepper JN,Jones JG,Menon DK

更新日期：1998-11-01 00:00:00

abstract：:Dexmedetomidine has become a popular sedative in the intensive care unit for patients undergoing mechanical ventilation because of its highly selective α-2 agonism, which exerts a combination of anesthetic, analgesic, and anxiolytic effects. Bradycardia and hypotension have been reported as the most common side effect...

journal_title：Anesthesia and analgesia

authors： Pratt A,Aboudara M,Lung L

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in compar...

journal_title：Anesthesia and analgesia

authors： Hunt R,Dienemann J,Norton HJ,Hartley W,Hudgens A,Stern T,Divine G

更新日期：2013-09-01 00:00:00