Ondansetron blocks nifedipine-induced analgesia in rats.

abstract：UNLABELLED:We evaluated in a qualitative systematic review the effect of N-methyl-D-aspartate (NMDA) receptor antagonists on reducing postoperative pain and analgesic consumption beyond the clinical duration of action of the target drug (preventive analgesia). Randomized trials examining the use of an NMDA antagonist i...

journal_title：Anesthesia and analgesia

authors： McCartney CJ,Sinha A,Katz J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:β3 containing γ-aminobutyric acid type A receptors (GABA(A)-Rs) mediate behavioral end points of IV anesthetics such as immobility and hypnosis. A knockout mouse with targeted forebrain deletion of the β3 subunit of the GABA(A)-R shows reduced sensitivity to the hypnotic effect of etomidate, as measured by t...

journal_title：Anesthesia and analgesia

authors： Rau V,Oh I,Liao M,Bodarky C,Fanselow MS,Homanics GE,Sonner JM,Eger EI 2nd

更新日期：2011-09-01 00:00:00

abstract：UNLABELLED:Pain management has become a notable feature of public health policy and mass media communication in France over the past few years. To assess the evolution of the knowledge and attitudes of the French population with respect to pain management and morphine use, telephone surveys using similar questionnaires...

journal_title：Anesthesia and analgesia

authors： Larue F,Fontaine A,Brasseur L

更新日期：1999-09-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:Attempted pulmonary artery catheterization via the left internal jugular vein resulted in a misdiagnosis of pulmonary hypertension before transesophageal echocardiography revealed the catheter positioned in the ascending aorta. Inadvertent aortic cannulation through an unusual type of partial anomalous pulmonary venou...

journal_title：Anesthesia and analgesia

authors： Siegmueller C,Bell A,Mittal T,George S

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Thoracic epidural anesthesia is often used as a postoperative analgesic technique in thoracic surgery. However, the structure of the overlapping spinous processes, resulting in interlaminar space occlusion, often makes thoracic epidural needle placement difficult. With the development of multi-detector row s...

journal_title：Anesthesia and analgesia

authors： Murata H,Sakai T,Goto S,Sumikawa K

更新日期：2008-02-01 00:00:00

abstract：UNLABELLED:Adjuncts to local anesthetics for peripheral plexus blockade may enhance the quality and duration of anesthesia and postoperative analgesia. The analgesic, tramadol, has a unique mechanism of action that suggests efficacy as such an adjunct. It displays a central analgesic and peripheral local anesthetic eff...

journal_title：Anesthesia and analgesia

authors： Robaux S,Blunt C,Viel E,Cuvillon P,Nouguier P,Dautel G,Boileau S,Girard F,Bouaziz H

更新日期：2004-04-01 00:00:00

abstract：:Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injur...

journal_title：Anesthesia and analgesia

authors： van Caster P,Eiling S,Boekholt Y,Behmenburg F,Dorsch M,Heinen A,Hollmann MW,Huhn R

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Inhalation agents are being used in place of intravenous agents to provide sedation in some intensive care units. We performed a systematic review and meta-analysis of prospective randomized controlled trials, which compared the use of volatile agents versus intravenous midazolam or propofol in critical care...

journal_title：Anesthesia and analgesia

authors： Jerath A,Panckhurst J,Parotto M,Lightfoot N,Wasowicz M,Ferguson ND,Steel A,Beattie WS

更新日期：2017-04-01 00:00:00

abstract：UNLABELLED:Opioid medication is the mainstay of therapy for severe acute and chronic pain. Unfortunately, the side effects of these medications can affect patient comfort and safety, thus limiting their proven therapeutic potential. Whereas the main analgesic effects of opioids are centrally mediated, many of the commo...

journal_title：Anesthesia and analgesia

authors： Bates JJ,Foss JF,Murphy DB

更新日期：2004-01-01 00:00:00

abstract：UNLABELLED:Although the importance of the nucleus raphe magnus in descending inhibitory control of nociception is clear, it is not known whether these effects are equivalent for different types of nociception. Thus, we examined the differential inhibition of behavioral responses evoked by A delta or C fiber thermonocic...

journal_title：Anesthesia and analgesia

authors： Lu Y,Sweitzer SM,Laurito CE,Yeomans DC

更新日期：2004-02-01 00:00:00

abstract：:Epistaxis and airway trauma are often associated with nasotracheal intubation. We describe a patient with Factor IX deficiency who required nasotracheal intubation. An inexpensive, nonproprietary, rapid technique was used to reduce the trauma of intubation. ...

journal_title：Anesthesia and analgesia

authors： Delgado AV,Sanders JC

更新日期：2004-10-01 00:00:00

abstract：:A 62-yr-old man presented for a microdirect laryngoscopy and vocal cord fat grafting under jet ventilation. After a prolonged laryngoscopy, the patient developed hypercapnea and upper airway obstruction secondary to traumatic epiglottitis. The placement of a laryngeal mask airway provided ventilation and allowed for d...

journal_title：Anesthesia and analgesia

authors： Kidani DC,Shah NK

更新日期：2007-12-01 00:00:00

abstract：:Lidocaine catabolism under N2O anesthesia was evaluated in 5 dogs given a lidocaine infusion of 2 mg/kg/min for 20 minutes. Comparison of results with those of a prior similar study with halothane to be significantly faster in the animals given N2O. The extraction ratio for lidocaine, which did not vary with its arter...

journal_title：Anesthesia and analgesia

authors： Burney RG,DiFazio CA

更新日期：1976-05-01 00:00:00

abstract：:Previous studies have shown that the anesthetic potency of organic compounds increases as a given halogen is replaced with successively larger halogens. These studies often are limited in the accuracy of determination of potency, rarely correlate potency with physical properties, and usually fail to include ether comp...

journal_title：Anesthesia and analgesia

authors： Targ AG,Yasuda N,Eger EI 2nd,Huang G,Vernice GG,Terrell RC,Koblin DD

更新日期：1989-05-01 00:00:00

abstract：:The value of family-centered care in general and subspecialty pediatrics has been well documented in the literature. Translation of these principles into perioperative medicine has its logistical challenges; however, there are theoretical benefits. Specifically, pediatric patients with psychiatric diagnoses or special...

journal_title：Anesthesia and analgesia

authors： Ambardekar AP,Litman RS,Schwartz AJ

更新日期：2013-06-01 00:00:00

abstract：UNLABELLED:Victims of minor trauma transported by paramedic-based rescue systems are usually monitored with pulse oximetry. Under the difficult surroundings of prehospital trauma care, pulse oximeters show considerable periods of malfunction. We tested the hypothesis that capnography is a good, easy to use tool for mon...

journal_title：Anesthesia and analgesia

authors： Kober A,Schubert B,Bertalanffy P,Gorove L,Puskas T,Gustorff B,Joldzo A,Hoerauf K

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Hypotension compromises local tissue perfusion, thereby reducing tissue oxygenation. Hypotension might thus be expected to promote infection. Hypotension on surgical wards, while usually less severe than intraoperative hypotension, is common and often prolonged. In this retrospective cohort study, we tested ...

journal_title：Anesthesia and analgesia

authors： Yilmaz HO,Babazade R,Leung S,Zimmerman NM,Makarova N,Saasouh W,Stocchi L,Gorgun E,Sessler DI,Turan A

更新日期：2018-11-01 00:00:00

abstract：:Forty neonates delivered by cesarean section were studied, half being delivered of mothers in whom anesthesia was induced with midazolam (0.3 mg/kg intravenously) and half of mothers given thiopental (4 mg/kg). At delivery, blood samples from mother and the umbilical vein were drawn for determination of plasma concent...

journal_title：Anesthesia and analgesia

authors： Bach V,Carl P,Ravlo O,Crawford ME,Jensen AG,Mikkelsen BO,Crevoisier C,Heizmann P,Fattinger K

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Acute lung injury is a recognized complication of lower limb ischemia-reperfusion that has been demonstrated experimentally and in the clinical setting of aortic surgery. The application of a tourniquet can cause lower limb ischemia-reperfusion in orthopedic surgery. We studied the effect of unilateral thigh...

journal_title：Anesthesia and analgesia

authors： Lin LN,Wang LR,Wang WT,Jin LL,Zhao XY,Zheng LP,Jin LD,Jiang LM,Xiong XQ

更新日期：2010-08-01 00:00:00

abstract：:Because deviations from the Meyer-Overton rule may provide insights into the attributes of the anesthetic site of action, we characterized the solubility of the n-alkanes in various hydrophobic solvents (n-tetradecane, olive oil, n-octanol, and lecithin) as well as saline using variations on standard techniques. Incre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Laster MJ,Liu J,Eger EI 2nd,Halsey MJ,Koblin DD

更新日期：1993-07-01 00:00:00

abstract：:External cephalic version is a technique that decreases the need for cesarean delivery in patients with breech presentation. Several techniques exist to increase the success of external cephalic version; however, there are no studies comparing different tocolytics in patients who also received neuraxial anesthesia. We...

journal_title：Anesthesia and analgesia

authors： Katz D,Riley K,Kim E,Beilin Y

更新日期：2020-03-01 00:00:00

abstract：:We studied the effect of halothane on the fetal cardiovascular system of six lambs in utero by measuring fetal heart rate and femoral arterial blood pressure and by injecting labeled microspheres during a control period and again after 60 and 90 min of halothane anesthesia administered to six pregnant ewes at an inspi...

journal_title：Anesthesia and analgesia

authors： Biehl DR,Tweed WA,Cote J,Wade JG,Sitar D

更新日期：1983-05-01 00:00:00

abstract：:Fentanyl pharmacokinetics was compared in two groups of adult patients, one group (n = 5) aged less than 50 years, and one group (n = 4) aged greater than 60 years. Despite equivalent doses of fentanyl (10 microgram/kg IV), serum drug concentrations were significantly higher in the older patient group. This was reflec...

journal_title：Anesthesia and analgesia

authors： Bentley JB,Borel JD,Nenad RE Jr,Gillespie TJ

更新日期：1982-12-01 00:00:00

abstract：UNLABELLED:Patients undergoing vascular surgery have a high risk of suffering major postoperative cardiac events. Preoperative myocardial ischemia as detected by Holter monitoring identifies a high-risk subgroup whose postoperative ischemia, similarly detected, seems to herald major cardiac events. In this study, we de...

journal_title：Anesthesia and analgesia

authors： Raby KE,Brull SJ,Timimi F,Akhtar S,Rosenbaum S,Naimi C,Whittemore AD

更新日期：1999-03-01 00:00:00

abstract：:The effects of different intubating doses of atracurium on the time of onset, and the effect of an additional dose of thiopental on intubating conditions, were studied in 72 patients divided into six groups (n = 12 in each). Stratified sampling was used to obtain an even sex distribution. Groups I, III, and V (control...

journal_title：Anesthesia and analgesia

authors： Naguib M,Abdulatif M,Gyasi HK,Absood GH

更新日期：1986-12-01 00:00:00

abstract：UNLABELLED:We investigated the effects of isoflurane-induced burst suppression, monitored with electroencephalography (EEG), on cerebral blood flow velocity (CBFV), cerebral oxygen extraction (COE), and autoregulation in 16 patients undergoing cardiac surgery. The experimental procedure was performed during nonpulsatil...

journal_title：Anesthesia and analgesia

authors： Reinsfelt B,Westerlind A,Houltz E,Ederberg S,Elam M,Ricksten SE

更新日期：2003-11-01 00:00:00

abstract：:Sepsis is characterized by myocardial depression and systemic vasodilation, both of which are most likely mediated by nitric oxide. Propofol inhibits nitric oxide synthase and may therefore be beneficial in sepsis. On the other hand, renal blood flow, known to be only minimally affected by propofol in healthy subjects...

journal_title：Anesthesia and analgesia

authors： Booke M,Armstrong C,Hinder F,Conroy B,Traber LD,Traber DL

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Pediatric chronic pain is very common and results in significant health care costs. Pediatric chronic pain is both an individual and a public health concern. The primary objective of this study was to generate a descriptive clinical profile of the patients referred to an anesthesiology-based pediatric chroni...

journal_title：Anesthesia and analgesia

authors： Vetter TR

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Propofol-evoked injection site pain is not observed with fospropofol. We hypothesized that unlike propofol, fospropofol does not activate the irritant receptor, transient receptor potential 1 (TRPA1). METHODS:We tested the hypothesis using electrophysiology and behavioral studies. RESULTS:Our data demonstr...

journal_title：Anesthesia and analgesia

authors： Patwardhan A,Edelmayer R,Annabi E,Price T,Malan P,Dussor G

更新日期：2012-10-01 00:00:00