Age and fentanyl pharmacokinetics.

abstract：:The direct effect of protamine sulfate upon myocardial inotropism was studied using an isolated canine heart muscle preparation. Isometric force (F) was decreased to 87.6 +/- 1.2% of control values by a concentration of 50 x 10(-3) g/L protamine, which is approximately equal to the estimated serum concentration of pro...

journal_title：Anesthesia and analgesia

authors： Iwatsuki N,Matsukawa S,Iwatsuki K

更新日期：1980-02-01 00:00:00

abstract：:Combinations of alpha 2 agonists and opiates are used in the clinical management of pain to harness their potential synergistic interaction for analgesia while limiting their side-effects. To better predict the clinical consequences of this combination, we studied the behavioral effects of dexmedetomidine, a highly se...

journal_title：Anesthesia and analgesia

authors： Hayashi Y,Guo TZ,Maze M

更新日期：1996-09-01 00:00:00

abstract：UNLABELLED:Diabetic patients are at increased risk of wound infection after major surgery, but the effect of perioperative glucose control on postoperative wound infection rates after surgery is uncertain. We tested the effect of an insulin infusion on perioperative neutrophil function in diabetic patients scheduled fo...

journal_title：Anesthesia and analgesia

authors： Rassias AJ,Marrin CA,Arruda J,Whalen PK,Beach M,Yeager MP

更新日期：1999-05-01 00:00:00

abstract：:This research determined the safety and efficacy of two small-dose infusions of dexmedetomidine by evaluating sedation, analgesia, cognition, and cardiorespiratory function. Seven healthy young volunteers provided informed consent and participated on three occasions with random assignment to drug or placebo. Heart rat...

journal_title：Anesthesia and analgesia

authors： Hall JE,Uhrich TD,Barney JA,Arain SR,Ebert TJ

更新日期：2000-03-01 00:00:00

abstract：:The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (i.v.) bolus followed by a continuous infusion after total hip or knee arthroplasty. After general anesthesia, patients received either placebo or ketorolac 30 mg i.v. ...

journal_title：Anesthesia and analgesia

authors： Etches RC,Warriner CB,Badner N,Buckley DN,Beattie WS,Chan VW,Parsons D,Girard M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify optimal target propofol and remifentanil concentrations to avoid a gag reflex in response to insertion of an upper gastrointestinal endoscope. METHODS:Patients presenting for endoscopy received target-controlled infusions (TCI) of both propofol and remifentanil for ...

journal_title：Anesthesia and analgesia

authors： Borrat X,Valencia JF,Magrans R,Gimenez-Mila M,Mellado R,Sendino O,Perez M,Nunez M,Jospin M,Jensen EW,Troconiz I,Gambus PL

更新日期：2015-07-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:Prepared endotracheal tubes (PETTs) are frequently used for unanticipated difficult intubation, but their storage time is highly variable and institution-dependent. We sought to determine first, if open, unused PETTs are a potential source of pathogenic microorganisms, and second, if PETTs can provide a medi...

journal_title：Anesthesia and analgesia

authors： Rasic NF,Friesen RM,Anderson B,Hoban SA,Olson N,Kress J

更新日期：2003-10-01 00:00:00

abstract：UNLABELLED:The Anesthetic Conserving Device (ACD) is a high-flow anesthesia system closed to volatile anesthetics only. We compared the ACD with a circle system under different fresh gas flow (FGF) conditions. Eighty-one patients undergoing major surgery were randomly allocated to receive sevoflurane from a circle circ...

journal_title：Anesthesia and analgesia

authors： Tempia A,Olivei MC,Calza E,Lambert H,Scotti L,Orlando E,Livigni S,Guglielmotti E

更新日期：2003-04-01 00:00:00

abstract：UNLABELLED:In this study, we sought to determine the minimum analgesic doses and relative potencies of fentanyl and sufentanil when they are used as the sole epidural analgesic during the first stage of labor. Nulliparous parturients (n = 66) in spontaneous labor at term gestation and requesting epidural analgesia were...

journal_title：Anesthesia and analgesia

authors： Capogna G,Camorcia M,Columb MO

更新日期：2003-04-01 00:00:00

abstract：:Many inhaled anesthetics and intravenous analgesics have been alleged to produce both proconvulsant and anticonvulsant activity in humans. The reasons for these contrasting actions on the CNS are poorly understood at the present time. However, biologic variability plays an important role in determining individual pati...

journal_title：Anesthesia and analgesia

authors： Modica PA,Tempelhoff R,White PF

更新日期：1990-03-01 00:00:00

abstract：:In vitro experiments using guinea pig tracheal smooth muscle were performed to compare the relaxant properties of procaine, lidocaine, and ketamine following contracture induced by histamine. Procaine produced a spasmolytic effect in a dose-related manner. In the doses tested, relaxation induced by procaine was more p...

journal_title：Anesthesia and analgesia

authors： Wanna HT,Gergis SD

更新日期：1978-01-01 00:00:00

abstract：:The effects of continuous epidural anesthesia and of general anesthesia on the incidence of thromboembolism following total hip replacement were studied. Sixty patients were randomly allotted to one of two groups receiving either epidural or general anesthesia. Epidural anesthesia (N = 30) consisted of 0.5% bupivacain...

journal_title：Anesthesia and analgesia

authors： Modig J,Borg T,Karlström G,Maripuu E,Sahlstedt B

更新日期：1983-02-01 00:00:00

abstract：UNLABELLED:Reduction of the inflammatory reaction with the use of heparin coating has been found during and after cardiopulmonary bypass (CPB). The question remains whether this reduced reaction also decreases the magnitude of CPB-induced pulmonary dysfunction. We therefore evaluated the effects of a heparin-coated cir...

journal_title：Anesthesia and analgesia

authors： de Vroege R,van Oeveren W,van Klarenbosch J,Stooker W,Huybregts MA,Hack CE,van Barneveld L,Eijsman L,Wildevuur CR

更新日期：2004-06-01 00:00:00

abstract：IMPLICATIONS:This case describes the impact of argatroban and off-pump coronary revascularization on hemostasis as assessed by conventional hemostatic measures and Thrombelastography in a patient with heparin-induced thrombocytopenia. ...

journal_title：Anesthesia and analgesia

authors： Kieta DR,McCammon AT,Holman WL,Nielsen VG

更新日期：2003-04-01 00:00:00

abstract：:Two concentrations of etidocaine (1 and 1.5%) and of pH-adjusted bupivacaine (0.5 and 0.75%, pH 6.8), all fortified with hyaluronidase, were compared as local anesthetics in regional ophthalmic surgery for cataract extraction. The series comprised 160 patients assigned randomly to four groups (n = 40). Each patient re...

journal_title：Anesthesia and analgesia

authors： Sarvela PJ

更新日期：1993-07-01 00:00:00

abstract：:A low approach to the interscalene block (LISB) deposits local anesthetic farther caudad on the brachial plexus compared with the conventional interscalene block (ISB). We compared the efficacy of LISB and ISB in achieving anesthesia of the distal extremity in 254 patients having upper extremity surgery. The most freq...

journal_title：Anesthesia and analgesia

authors： Kim JH,Chen J,Bennett H,Lesser JB,Resta-Flarer F,Barczewska-Hillel A,Byrnes P,Santos AC

更新日期：2011-04-01 00:00:00

abstract：:In Japan, an ever-present problem in the preoperative evaluation of patients with ischemic heart disease is that although such evaluations are based on Western data, these data serve as the basis for determining perioperative risk in Japanese patients. To remedy this problem, the Cardiac Ischemia and Anesthesia Resear...

journal_title：Anesthesia and analgesia

authors： Seki M,Kashimoto S,Nagata O,Yoshioka H,Ishiguro T,Nishimura K,Honda O,Sakamoto A,Omi A,Ogihara Y,Fujimoto K,Iwade M,Yamada T,Nomura M,Takeda J

更新日期：2005-05-01 00:00:00

abstract：UNLABELLED:Recent reports have discussed the potential risk of transient radicular irritation (TRI) after spinal anesthesia with lidocaine. Because we have not encountered such neurologic sequelae with the high incidence reported, we prospectively examined the incidence of TRI after spinal anesthesia with lidocaine. On...

journal_title：Anesthesia and analgesia

authors： Morisaki H,Masuda J,Kaneko S,Matsushima M,Takeda J

更新日期：1998-05-01 00:00:00

abstract：:Computer-based measuring of the level of sedation and hypnosis is difficult and has proven to be challenging. The electroencephalogram (EEG) has been proposed as a potential method. Response entropy (RE) and state entropy (SE) are multifactor, dimensionless parameters of a new technology of EEG monitoring, and we inve...

journal_title：Anesthesia and analgesia

authors： Litscher G

更新日期：2006-06-01 00:00:00

abstract：:If there is a genetic predisposition to excessive bleeding, there should be an association in excessive blood loss between multiple cardiac surgeries. We retrospectively determined in 174 patients the association of excessive bleeding between 2 cardiac surgeries with cardiopulmonary bypass between January 19, 1990 and...

journal_title：Anesthesia and analgesia

authors： Nuttall GA,Henderson N,Quinn M,Blair C,Summers L,Williams BA,Oliver WC,Santrach PJ

更新日期：2006-04-01 00:00:00

abstract：:We studied 49 patients of ASA physical status I to determine cerebral anesthetic concentration on awakening calculated with end-tidal anesthetic concentration, when the end-tidal concentration decreased spontaneously. We also attempted to explain the difference in the average of the bracketing alveolar anesthetic conc...

journal_title：Anesthesia and analgesia

authors： Katoh T,Suguro Y,Kimura T,Ikeda K

更新日期：1993-11-01 00:00:00

abstract：UNLABELLED:We compared the recovery profile and postoperative SpO(2) after the administration of general anesthesia with either sevoflurane-remifentanil or sevoflurane-sufentanil in 30 healthy patients undergoing upper abdominal surgery. They were randomly allocated to receive general anesthesia with sevoflurane and sm...

journal_title：Anesthesia and analgesia

authors： Casati A,Albertin A,Fanelli G,Deni F,Berti M,Danelli G,Grifoni F,Torri G

更新日期：2000-11-01 00:00:00

abstract：:We report a case of possible air embolism during a three-port pars plana vitrectomy and air-fluid exchange of the vitreous cavity of the eye. After the start of intraocular air flushing, sudden tachycardia, a decrease in oxygen saturation and end-tidal carbon dioxide tension, and a distinct "mill-wheel" murmur were ob...

journal_title：Anesthesia and analgesia

authors： Ledowski T,Kiese F,Jeglin S,Scholz J

更新日期：2005-06-01 00:00:00

abstract：UNLABELLED:Supraclavicular nerve blocks are effective but may be complicated by pneumothorax. We hypothesized that, to avoid this complication, the depths of the brachial plexus and the lung could be estimated to guide needle placement. In 17 patients undergoing surgical relief of thoracic outlet syndrome, we designate...

journal_title：Anesthesia and analgesia

authors： Cornish PB,Greenfield LJ,O'Reilly M,Allan L

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Intraoperative hypoglycemia can result in devastating neurologic injury if not promptly diagnosed and treated. Few studies have defined risk factors for intraoperative hypoglycemia. The authors sought to characterize children with intraoperative hypoglycemia and determine independent risk factors in a multic...

journal_title：Anesthesia and analgesia

authors： Riegger LQ,Leis AM,Golmirzaie KH,Malviya S

更新日期：2020-06-25 00:00:00

abstract：BACKGROUND:In the present study, we examined the effects and mechanisms of the Chinese herb resveratrol on attenuation of morphine tolerance in rats. METHODS:Male Wistar rats were implanted with 2 intrathecal catheters; one catheter was connected to a mini-osmotic pump, used for either morphine (15 μg/h) or saline (1 ...

journal_title：Anesthesia and analgesia

authors： Tsai RY,Chou KY,Shen CH,Chien CC,Tsai WY,Huang YN,Tao PL,Lin YS,Wong CS

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:A single preoperative dose of 600 mg gabapentin, combined with multimodal analgesia, has previously been shown to reduce postcesarean pain and improve maternal satisfaction but was associated with increased maternal sedation. We hypothesized that a lower dose of gabapentin may be effective with less sedation...

journal_title：Anesthesia and analgesia

authors： Short J,Downey K,Bernstein P,Shah V,Carvalho JC

更新日期：2012-12-01 00:00:00

abstract：:While a large number of studies has examined the efficacy of opioid-sparing analgesics in adult surgical populations, fewer studies are available to guide postoperative pain treatment in pediatric patients. We systematically reviewed available publications on the use of systemic nonopioid agents for postoperative anal...

journal_title：Anesthesia and analgesia

authors： Zhu A,Benzon HA,Anderson TA

更新日期：2017-11-01 00:00:00

abstract：:This investigation examined the role of myocardial adenosine triphosphate-regulated potassium (KATP) channels in isoflurane-induced enhancement of myocardial function after reversible tissue injury produced by a 15-min left anterior descending coronary artery occlusion (LAD) and reperfusion. Dogs (n = 14) were chronic...

journal_title：Anesthesia and analgesia

authors： Kersten JR,Lowe D,Hettrick DA,Pagel PS,Gross GJ,Warltier DC

更新日期：1996-07-01 00:00:00