Glyburide, a KATP channel antagonist, attenuates the cardioprotective effects of isoflurane in stunned myocardium.

abstract：UNLABELLED:In a prospective, randomized, double-blinded study, we evaluated the efficacy of granisetron and ramosetron for preventing postoperative nausea and vomiting (PONV) in major gynecologic surgery. One hundred twenty patients, ASA physical status I or II, aged 23-65 yr, received i.v. granisetron 2.5 mg or ramose...

journal_title：Anesthesia and analgesia

authors： Fujii Y,Saitoh Y,Tanaka H,Toyooka H

更新日期：1999-08-01 00:00:00

abstract：:Previous studies have suggested that shocks of 5-10 J are required for direct ventricular defibrillation during open heart surgery. However, the efficacy of shocks of less than 5 J, the effects of thermal, biochemical, and temporal factors, and the influence of disease process on defibrillation have not been fully inv...

journal_title：Anesthesia and analgesia

authors： Lake CL,Sellers TD,Nolan SP,Crosby IK,Wellons HA Jr,Crampton RS

更新日期：1984-08-01 00:00:00

abstract：:We investigated the appropriateness of the somatosensory evoked potentials (SSEPs) as an objective monitor of sensory blockade of the ulnar nerve by comparing the effects of saline and lidocaine infiltration of the ulnar nerve at the elbow, with and without epinephrine. The four treatments were administered in random ...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Toleikis JR,Shanks C,Ramseur A,Sloan T

更新日期：1986-08-01 00:00:00

abstract：UNLABELLED:We designed this study to assess the efficacy of dolasetron compared with clonidine and placebo in prophylaxis of postanesthetic shivering. We included 90 patients undergoing elective abdominal or urologic surgery. The patients were randomly assigned to one three groups (each group n = 30) using a double-bli...

journal_title：Anesthesia and analgesia

authors： Piper SN,Röhm KD,Maleck WH,Fent MT,Suttner SW,Boldt J

更新日期：2002-01-01 00:00:00

abstract：:Isoflurane-oxygen was given for induction and maintenance of anesthesia to ten patients having coronary artery bypass grafts. All had preserved ventricular function without hypertension or other cardiac lesions; treatment with beta-blocking drugs was maintained until the operation in all patients. Cardiac output, arte...

journal_title：Anesthesia and analgesia

authors： Moffitt EA,Barker RA,Glenn JJ,Imrie DD,DelCampo C,Landymore RW,Kinley CE,Murphy DA

更新日期：1986-01-01 00:00:00

abstract：:A previous demonstration that the ratio of analgesic to anesthetic endpoints is not constant across inhalation anesthetic agents implies that more than one mechanism of action may be operant in general anesthesia. We hypothesized that the endogenous opiate systems might account for this observed disparity in ratios. T...

journal_title：Anesthesia and analgesia

authors： Levine LL,Winter PM,Nemoto EM,Uram M,Lin MR

更新日期：1986-04-01 00:00:00

abstract：:Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a st...

journal_title：Anesthesia and analgesia

authors： Katz D,Hamburger J,Batt D,Zahn J,Beilin Y

更新日期：2019-09-01 00:00:00

abstract：:This study evaluated interspecies sensitivity and ability to resuscitate pentobarbital anesthetized sheep and dogs after cardiovascular toxic doses of bupivacaine. Every minute, 3 mg/kg of bupivacaine was injected into the right atrium over the course of 10 sec until cardiovascular collapse occurred. While the bupivac...

journal_title：Anesthesia and analgesia

authors： Kasten GW,Martin ST

更新日期：1986-10-01 00:00:00

abstract：:Elevated serum ammonia may play a role in central nervous system derangement after transurethral resection of the prostate. Glycine used as a surgical irrigant for prostate resection produces ammonia as a by-product after liver and renal metabolism. The presence of liver dysfunction often leads to an inability to remo...

journal_title：Anesthesia and analgesia

authors： Frink EJ Jr,DiGiovanni DA,Davis JR,Brown BR Jr

更新日期：1989-12-01 00:00:00

abstract：:This study evaluated the role of nitric oxide (NO) in spinal cord nociceptive transmission during peripheral inflammation evoked by formalin injection into the rat paw, using N omega-nitro-L-arginine (N-Arg), an NO synthase inhibitor. Male rats were prepared with intrathecal (IT) catheters. To quantify the formalin re...

journal_title：Anesthesia and analgesia

authors： Yamamoto T,Shimoyama N,Mizuguchi T

更新日期：1993-11-01 00:00:00

abstract：UNLABELLED:Takayasu's arteritis is a rare, chronic progressive panendarteritis involving the aorta and its main branches. Anesthesia for patients with Takayasu's arteritis is complicated by their severe uncontrolled hypertension, end-organ dysfunction resulting from hypertension, stenosis of major blood vessels affecti...

journal_title：Anesthesia and analgesia

authors： Kathirvel S,Chavan S,Arya VK,Rehman I,Babu V,Malhotra N,Bhukal I,Chari P

更新日期：2001-07-01 00:00:00

abstract：INTRODUCTION:During magnetic resonance imaging (MRI), children are at risk for body temperature variations. The cold MRI environment that preserves the MRI magnet can cause serious hypothermia. On the other hand, hyperthermia may also develop because of radiofrequency-induced heating of the tissues, particularly in pro...

journal_title：Anesthesia and analgesia

authors： Nasr VG,Schumann R,Bonney I,Diaz L,Ahmed I

更新日期：2012-06-01 00:00:00

abstract：:When given for a sufficient time and dose intravenously, neuromuscular blocking drugs eventually can enter the cerebrospinal fluid (CSF). To study the potential pharmacologic consequences of neuromuscular blocking drugs in the CSF, a model was developed in the rat by using an intrathecal infusion of these drugs. A can...

journal_title：Anesthesia and analgesia

authors： Szenohradszky J,Trevor AJ,Bickler P,Caldwell JE,Sharma ML,Rampil IJ,Miller RD

更新日期：1993-06-01 00:00:00

abstract：:Isoproterenol 5 micrograms may be an effective marker of accidental intravascular injection in women in labor; however, before isoproterenol can be incorporated in routinely used epidural test doses, the safety and usefulness should be determined in an animal model. This study was designed to examine the hemodynamic e...

journal_title：Anesthesia and analgesia

authors： Marcus MA,Vertommen JD,Van Aken H,Wouters PF

更新日期：1996-05-01 00:00:00

abstract：UNLABELLED:Economic considerations suggest that it is desirable to keep operating rooms fully used when staffed, but the optimum utilization of an operating room (OR) is not known. We created a simulation of an OR to define optimum utilization. We set operational goals of having cases start within 15 min of the schedul...

journal_title：Anesthesia and analgesia

authors： Tyler DC,Pasquariello CA,Chen CH

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Frailty, a state of decreased physiological reserve, is strongly associated with perioperative mortality in older adults. However, the mechanism by which frailty is associated with mortality is not yet understood. Autonomic dysfunction in the form of decreased intraoperative hemodynamic variability has been ...

journal_title：Anesthesia and analgesia

authors： James LA,Levin MA,Lin HM,Deiner SG

更新日期：2019-06-01 00:00:00

abstract：IMPLICATIONS:Misplacement of an epidural catheter into the subarachnoid space is a recognized complication. However, breakage of an intrathecal epidural catheter during removal presents a dilemma. Appropriate imaging, a neurosurgical consultation, and aggressive surgical exploration and extraction of the retained piece...

journal_title：Anesthesia and analgesia

authors： Ugboma S,Au-Truong X,Kranzler LI,Rifai SH,Joseph NJ,Salem MR

更新日期：2002-10-01 00:00:00

abstract：:Cytokine release during surgery can produce a long-lasting hyperalgesia. Thus, preoperatively-administered cytokine inhibitors might reduce the production of cytokines, decreasing central nervous system sensitization and improving the quality of postoperative pain relief. We investigated the hypothesis that preincisio...

journal_title：Anesthesia and analgesia

authors： Lu CH,Chao PC,Borel CO,Yang CP,Yeh CC,Wong CS,Wu CT

更新日期：2004-11-01 00:00:00

abstract：UNLABELLED:Using a randomized, double-blind protocol design, we compared a new lower-lipid emulsion of propofol (Ampofol) containing propofol 1%, soybean oil 5%, and egg lecithin 0.6% with the most commonly used formulation of propofol (Diprivan) with respect to onset of action and recovery profiles, as well as intraop...

journal_title：Anesthesia and analgesia

authors： Song D,Hamza M,White PF,Klein K,Recart A,Khodaparast O

更新日期：2004-03-01 00:00:00

abstract：UNLABELLED:Pain on injection of propofol continues to be a problem for anesthesiologists. A lipid-free formulation of propofol and a propofol emulsion containing medium-chain triglyceride have become available in the Indian market. We performed this study to assess the pain on injection of propofol emulsion containing ...

journal_title：Anesthesia and analgesia

authors： Dubey PK,Kumar A

更新日期：2005-10-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:Evaluation of a new inhaled anesthetic requires determination of the anesthetic's potential to predispose to ventricular (and other) arrhythmias in an animal model. This need poses logistic and economic burdens if the effects of large numbers of new anesthetics are to be surveyed. We have devised a technique for deter...

journal_title：Anesthesia and analgesia

authors： Laster MJ,Johnson BH,Eger EI 2nd,Taheri S

更新日期：1990-06-01 00:00:00

abstract：:Combinations of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids are widespread in the management of pain, allowing better analgesia with reduced side effects. Cannabinoids are promising analgesic drugs that have pharmacological properties similar to those of opioids. However, the beneficial effects of cannabi...

journal_title：Anesthesia and analgesia

authors： Ulugöl A,Ozyigit F,Yesilyurt O,Dogrul A

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:We evaluated the interaction of dopamine-proxymetacaine and dopamine- oxybuprocaine antinociception using isobolograms. METHODS:This experiment uses subcutaneous drug (proxymetacaine, oxybuprocaine, and dopamine) injections under the skin of the rat's back, thus simulating infiltration blocks. The dose-rela...

journal_title：Anesthesia and analgesia

authors： Chen YW,Chiu CC,Lin HT,Wang JJ,Hung CH

更新日期：2018-05-01 00:00:00

abstract：:The correlation between the potency of inhaled anesthetics and their solubility in a hydrophobic phase provides an opportunity to define better the characteristics of the anesthetic site of action. The correlation implies that inhaled anesthetics act in a hydrophobic site and that the solvent used has properties repre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Halsey MJ,Liu J,Eger EI 2nd,Koblin DD,Laster MJ

更新日期：1991-05-01 00:00:00

abstract：:Malignant hyperthermia syndrome associated with various anesthetic agents has been well documented, but none has been reported with enflurane (Ethrane). This particular case is the first involving exposure for the second time to enflurane anesthesia after a six-month interval in which malignant hyperthermia resulted. ...

journal_title：Anesthesia and analgesia

authors： Pan TH,Wollack AR,DeMarco JA

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:It remains unknown whether continuous or scheduled intermittent bolus local anesthetic administration is preferable for transversus abdominis plane (TAP) catheters. We therefore tested the hypothesis that when using TAP catheters, providing local anesthetic in repeated bolus doses increases the cephalad-caud...

journal_title：Anesthesia and analgesia

authors： Khatibi B,Said ET,Sztain JF,Monahan AM,Gabriel RA,Furnish TJ,Tran JT,Donohue MC,Ilfeld BM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Signal transduction cascade of anesthetic-induced preconditioning has been extensively studied, yet many aspects of it remain unsolved. Here, we investigated the roles of reactive oxygen species (ROS) and mitochondrial uncoupling in cardiomyocyte preconditioning by two modern volatile anesthetics: desflurane...

journal_title：Anesthesia and analgesia

authors： Sedlic F,Pravdic D,Ljubkovic M,Marinovic J,Stadnicka A,Bosnjak ZJ

更新日期：2009-08-01 00:00:00

abstract：UNLABELLED:Epidural catheters (EC) are often used in pediatric patients for intraoperative and postoperative pain relief. The small anatomical structures and catheter insertion under general anesthesia make it more difficult to perform EC and to prevent damage. In this study we investigated the use of ultrasound (US) i...

journal_title：Anesthesia and analgesia

authors： Rapp HJ,Folger A,Grau T

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

journal_title：Anesthesia and analgesia

authors： Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

更新日期：2018-08-01 00:00:00