Procaine, lidocaine, and ketamine inhibit histamine-induced contracture of guinea pig tracheal muscle in vitro.

Abstract:

:In vitro experiments using guinea pig tracheal smooth muscle were performed to compare the relaxant properties of procaine, lidocaine, and ketamine following contracture induced by histamine. Procaine produced a spasmolytic effect in a dose-related manner. In the doses tested, relaxation induced by procaine was more pronounced than that produced by either lidocaine or ketamine, although the latter 2 drugs also had a significant spasmolytic effect.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Wanna HT,Gergis SD

doi

10.1213/00000539-197801000-00005

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

25-7

issue

1

eissn

0003-2999

issn

1526-7598

journal_volume

57

pub_type

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