Hepatic clearance of lidocaine during N2O anesthesia in dogs.

abstract：:Median convulsant (CD50) and median lethal (LD50) doses of intraperitoneal lidocaine, bupivacaine, and etidocaine were determined in 149 mice. Another 496 mice were pretreated with intramuscular diazepam, lorazepam, or midazolam, 1 mg/kg. Fifteen minutes later, lidocaine, bupivacaine, or etidocaine was given intraperi...

journal_title：Anesthesia and analgesia

authors： de Jong RH,Bonin JD

更新日期：1981-06-01 00:00:00

abstract：:This randomized double-blind study compared the hemodynamic and metabolic effects of pancuronium and vecuronium during treatment of shivering after cardiac surgery with hypothermic cardiopulmonary bypass. Thirty sedated and pain-free patients who shivered after cardiac surgery were treated with pancuronium (n = 15) or...

journal_title：Anesthesia and analgesia

authors： Dupuis JY,Nathan HJ,DeLima L,Wynands JE,Russell GN,Bourke M

更新日期：1994-09-01 00:00:00

abstract：:The contribution of the lung to the clearance of exogenous dopamine after cardiopulmonary bypass (CPB) was analyzed quantitatively in humans and compared with the contribution of the lung before CPB. The pulmonary and arterial plasma concentration of dopamine and the pulmonary plasma flow were measured simultaneously ...

journal_title：Anesthesia and analgesia

authors： Hayashi Y,Sumikawa K,Yamatodani A,Kamibayashi T,Mammoto T,Kuro M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Although the mechanical status of the lungs affects the shape of the capnogram, the relations between the capnographic parameters and those reflecting the airway and lung tissue mechanics have not been established in mechanically ventilated patients. We, therefore, set out to characterize how the mechanical ...

journal_title：Anesthesia and analgesia

authors： Csorba Z,Petak F,Nevery K,Tolnai J,Balogh AL,Rarosi F,Fodor GH,Babik B

更新日期：2016-05-01 00:00:00

abstract：UNLABELLED:We evaluated the effect of 1, 20, and 40 mL of epidural saline flush on recovery from lidocaine epidural anesthesia. Eight volunteers were studied for three study periods, each separated by 72 h. The volume of saline was randomized, and a new catheter was inserted for each study period. A standardized dose o...

journal_title：Anesthesia and analgesia

authors： Chan VW,Nazarnia S,Kaszas Z,Perlas A

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:In this study, we evaluated the feasibility and accuracy of Univent tube (Fuji Systems, Tokyo, Japan) placement with the aid of auscultation (AUS) or as guided by a lighted stylet (LS) compared with placement guided by the fiberoptic bronchoscope (FOB) or the blind intubation technique as recommended by the ...

journal_title：Anesthesia and analgesia

authors： Weng H,Xu ZY,Liu J,Ma D,Liu DS

更新日期：2010-02-01 00:00:00

abstract：UNLABELLED:We designed this study to assess the efficacy of dolasetron compared with clonidine and placebo in prophylaxis of postanesthetic shivering. We included 90 patients undergoing elective abdominal or urologic surgery. The patients were randomly assigned to one three groups (each group n = 30) using a double-bli...

journal_title：Anesthesia and analgesia

authors： Piper SN,Röhm KD,Maleck WH,Fent MT,Suttner SW,Boldt J

更新日期：2002-01-01 00:00:00

abstract：:We designed a prospective, randomized, double-blind study to evaluate the efficacy of the combination of intrathecal sufentanil with a low dose of local anesthetic in an attempt to prolong analgesia in labor. Fifty-two patients received one of the following intrathecal study solutions: 2.5 mg of bupivacaine; 10 microg...

journal_title：Anesthesia and analgesia

authors： Campbell DC,Camann WR,Datta S

更新日期：1995-08-01 00:00:00

abstract：UNLABELLED:Intravenous and volatile general anesthetics inhibit norepinephrine (NE) release from sympathetic neurons and other neurosecretory cells. However, the actions of general anesthetics on NE release from central nervous system (CNS) neurons are unclear. We investigated the effects of representative IV and volat...

journal_title：Anesthesia and analgesia

authors： Pashkov VN,Hemmings HC Jr

更新日期：2002-11-01 00:00:00

abstract：:A 91-yr-old man (57 kg, 156 cm, ASA III) received an infraclavicular brachial plexus block for surgery of bursitis of the olecranon. Twenty minutes after infraclavicular injection of 30 mL of mepivacaine 1% (Scandicain) and 5 min after supplementation of 10 mL of prilocaine 1% (Xylonest) using an axillary approach, th...

journal_title：Anesthesia and analgesia

authors： Litz RJ,Roessel T,Heller AR,Stehr SN

更新日期：2008-05-01 00:00:00

abstract：:Halothane, enflurane, isoflurane, and fentanyl were examined for their potential to exacerbate liver dysfunction in rats with preexisting cirrhosis. Male Wistar rats given sodium phenobarbital for 2 weeks are assigned randomly to two groups. One group (cirrhotic) was exposed by inhalation to carbon tetrachloride (CCl4...

journal_title：Anesthesia and analgesia

authors： Baden JM,Kundomal YR,Luttropp ME Jr,Maze M,Kosek JC

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Hypotension after spinal anesthesia for cesarean delivery is common. Previous studies have demonstrated that a crystalloid fluid "coload" (rapid administration of a fluid bolus starting at the time of intrathecal injection) is superior to the conventional crystalloid preload (fluid administered before the in...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Nasr VG,Taha SK,Zbeide RA,Shehade JM,Al Alami AA,Mokadem FH,Abdallah FW,Baraka AS,Aouad MT

更新日期：2009-10-01 00:00:00

abstract：:It is not uncommon to observe prolonged CNS depression for several hours following controlled hypotension and halothane anesthesia for neurosurgery. The present study evaluates possible contribution of large doses of trimethaphan to CNS depression. Four adult sheep were placed on transapical left ventricular bypass (T...

journal_title：Anesthesia and analgesia

authors： Wong KC,Peters JL,Roberts TS,McRea JC,Fukumasu H

更新日期：1977-01-01 00:00:00

abstract：:Tranexamic acid (TA) is a synthetic drug that inhibits fibrinolysis. It has been administered to decrease the use of blood products during cardiac surgery and orthotopic liver transplantation when infused in larger doses. A small-dose infusion of aprotinin causes a reduction in fibrinolysis and blood product requireme...

journal_title：Anesthesia and analgesia

authors： Kaspar M,Ramsay MA,Nguyen AT,Cogswell M,Hurst G,Ramsay KJ

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Blood hemoglobin can be monitored continuously and noninvasively with a noninvasive spectrophotometric sensor (Masimo SpHb). The perfusion index (PI) of the finger is directly related to the clinical accuracy of SpHb. We evaluated those variables that influence PI without the influences of surgery and anesth...

journal_title：Anesthesia and analgesia

authors： Miller RD,Ward TA,McCulloch CE,Cohen NH

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Recent research suggests that 6% hydroxyethyl starch (HES) 130/0.4 is one of the most frequently used resuscitation fluids worldwide. The retraction of studies evaluating its use necessitates a reevaluation of available evidence regarding its safety and efficacy. METHODS:We performed a systematic review and...

journal_title：Anesthesia and analgesia

authors： Gattas DJ,Dan A,Myburgh J,Billot L,Lo S,Finfer S,CHEST Management Committee.

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Studies in a variety of disciplines have shown that the readability of Web-based patient education materials is above that of the sixth grade reading level recommended by the U.S. Department of Health and Human Services. The aim of this study was to evaluate the readability, content, and quality of English- ...

journal_title：Anesthesia and analgesia

authors： Patel SK,Gordon EJ,Wong CA,Grobman WA,Goucher H,Toledo P

更新日期：2015-11-01 00:00:00

abstract：:Evaluation of a new inhaled anesthetic requires determination of the anesthetic's potential to predispose to ventricular (and other) arrhythmias in an animal model. This need poses logistic and economic burdens if the effects of large numbers of new anesthetics are to be surveyed. We have devised a technique for deter...

journal_title：Anesthesia and analgesia

authors： Laster MJ,Johnson BH,Eger EI 2nd,Taheri S

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The recommended treatment of suspected tension pneumothorax is immediate needle decompression. Recommended sites and needle sizes for this procedure vary, and there are published reports of failed decompression as well as iatrogenic hemothorax. We investigated the optimal needle length and relative safety of...

journal_title：Anesthesia and analgesia

authors： Wax DB,Leibowitz AB

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:We evaluated in which anatomic layer (above the fascia [AF] or below the fascia [BF]) wound infusion of bupivacaine has the best effect on postoperative pain after abdominal hysterectomy. METHODS:Sixty-two ASA physical status I and II patients undergoing total abdominal hysterectomy and bilateral salpingo-o...

journal_title：Anesthesia and analgesia

authors： Hafizoglu MC,Katircioglu K,Ozkalkanli MY,Savaci S

更新日期：2008-12-01 00:00:00

abstract：:The original 1858 edition of John Snow's On Chloroform and Other Anaesthetics, from which came the Wood Library-Museum of Anesthesiology reprints in 1971 and 1989, was donated to the Wood Library-Museum by Ralph Waters of Madison, Wisconsin, in 1967. The book contains a message of appreciation to Waters, dated October...

journal_title：Anesthesia and analgesia

authors： Maltby JR,Bamforth BJ

更新日期：1990-09-01 00:00:00

abstract：UNLABELLED:Natural killer (NK) cells can lyse certain tumor cells as well as virally infected cells without prior sensitization. Animal studies have shown that general anesthesia (GA) alone or GA followed by surgery decreases both basal NK cytotoxicity and enhancement of NK activity by interferon (IFN). The purpose of ...

journal_title：Anesthesia and analgesia

authors： Kutza J,Gratz I,Afshar M,Murasko DM

更新日期：1997-10-01 00:00:00

abstract：:Although there have been several anecdotal reports of the use of buccal pulse oximeter monitoring (Spo2) when digital Spo2 monitoring cannot be used, there have been no objective evaluations of the accuracy of buccal Spo2 monitoring. The purpose of this study was to systematically compare buccal Spo2 monitoring to bot...

journal_title：Anesthesia and analgesia

authors： O'Leary RJ Jr,Landon M,Benumof JL

更新日期：1992-10-01 00:00:00

abstract：:All patients undergoing heart surgery experience a certain amount of nonspecific myocardial injury documented by the release of cardiac biomarkers and associated with poor outcome. We investigated the role of unipolar radiofrequency ablation of atrial fibrillation on the release of cardiac biomarkers in 71 patients un...

journal_title：Anesthesia and analgesia

authors： Zangrillo A,Crescenzi G,Landoni G,Benussi S,Crivellari M,Pappalardo F,Dorigo E,Pappone C,Alfieri O

更新日期：2005-07-01 00:00:00

abstract：:The antagonism of a pancuronium-curare (P + C) neuromuscular block was assessed and compared to the antagonism of a pancuronium (P) block. One group of seven patients received P + C (0.024 mg/kg + 0.144 mg/kg); another similar group of seven patients received P (0.07 mg/kg). Both groups were anesthetized with nitrous ...

journal_title：Anesthesia and analgesia

authors： Vitez TS,Difrancesco LV

更新日期：1983-12-01 00:00:00

abstract：UNLABELLED:This study examines the effect of spinal ibuprofen on the behavioral manifestations associated with the opioid abstinence syndrome. Rats (n = 8 per group) were infused for 5 days with morphine and then pretreated with a spinal bolus dose of ibuprofen before systemic naloxone antagonism (300 microg). Groups i...

journal_title：Anesthesia and analgesia

authors： Dunbar SA,Karamov IG,Buerkle H

更新日期：2000-08-01 00:00:00

abstract：:The aim of this study was to determine the need for supplemental oxygen during recovery from general anesthesia for ambulatory surgery in healthy women without obesity or respiratory disease. Arterial oxygen saturation by pulse oximetry (SpO2) was monitored throughout the first postoperative hour in 164 patients. The ...

journal_title：Anesthesia and analgesia

authors： Murray RS,Raemer DB,Morris RW

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Postoperative delirium is a major debilitating complication for patients and is associated with poor outcomes. Previous studies have suggested that excessive general anesthesia may lead to postoperative delirium. Electroencephalography (EEG)-based monitors have been administered in clinical practice in an at...

journal_title：Anesthesia and analgesia

authors： Sun Y,Ye F,Wang J,Ai P,Wei C,Wu A,Xie W

更新日期：2020-09-01 00:00:00

abstract：:The low solubility of sevoflurane in blood suggests that this agent should enter and leave the body more rapidly than isoflurane. However, the closeness of sevoflurane and isoflurane tissue/blood partition coefficients suggests that the rates of equilibration with and elimination from tissues should be similar. We tes...

journal_title：Anesthesia and analgesia

authors： Yasuda N,Lockhart SH,Eger EI 2nd,Weiskopf RB,Liu J,Laster M,Taheri S,Peterson NA

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:We have recently shown that levetiracetam, administered systemically, exerts an antihyperalgesic effect in a rat inflammatory pain model. In this study, we examined whether levetiracetam has local peripheral antihyperalgesic/anti-edematous effects in the same model of localized inflammation and whether opioi...

journal_title：Anesthesia and analgesia

authors： Stepanović-Petrović RM,Micov AM,Tomić MA,Ugrešić ND

更新日期：2012-12-01 00:00:00