Evidence-based management of critically ill patients: analysis and implementation.

abstract：:We measured the pharmacokinetics of hydromorphone in normal volunteers given three doses of the drug (10, 20, and 40 micrograms/kg) as intravenous 45-s injections on different days. Concentrations of hydromorphone in plasma from serial blood samples were measured by a high-performance liquid chromatography method spec...

journal_title：Anesthesia and analgesia

authors： Hill HF,Coda BA,Tanaka A,Schaffer R

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Thoracic epidural anesthesia is often used as a postoperative analgesic technique in thoracic surgery. However, the structure of the overlapping spinous processes, resulting in interlaminar space occlusion, often makes thoracic epidural needle placement difficult. With the development of multi-detector row s...

journal_title：Anesthesia and analgesia

authors： Murata H,Sakai T,Goto S,Sumikawa K

更新日期：2008-02-01 00:00:00

abstract：:The sedative effects of epidural anesthesia without volatile and IV anesthetics and quantification of the degree of epidural anesthesia-induced sedation have not been investigated. In the current study we evaluated the effects of epidural anesthesia on the bispectral index (BIS) during the awake phase and during gener...

journal_title：Anesthesia and analgesia

authors： Ishiyama T,Kashimoto S,Oguchi T,Yamaguchi T,Okuyama K,Kumazawa T

更新日期：2005-03-01 00:00:00

abstract：:The routine preoperative evaluation of pediatric patients often includes a history, physical examination, complete blood count, and urinalysis (UA). We retrospectively reviewed the records of 486 elective surgeries in children to determine the role of abnormal preoperative laboratory test results in perioperative mana...

journal_title：Anesthesia and analgesia

authors： O'Connor ME,Drasner K

更新日期：1990-02-01 00:00:00

abstract：UNLABELLED:We conducted this retrospective study to document the efficacy and safety, and demonstrate the spectrum of indications for subcutaneously tunneled epidural catheters in the management of prolonged pain in pediatric patients. The charts of 25 patients with prolonged pain that was unresponsive to conventional ...

journal_title：Anesthesia and analgesia

authors： Aram L,Krane EJ,Kozloski LJ,Yaster M

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that Homer 1b/c, a postsynaptic molecular scaffolding protein that binds and clusters metabotropic glutamate receptors at neuronal synapses, has an important role in the metabotropic glutamate receptor signaling process. In the current study, we investigated the possible in...

journal_title：Anesthesia and analgesia

authors： Yao YX,Jiang Z,Zhao ZQ

更新日期：2011-12-01 00:00:00

abstract：:This study defines some characteristics of a standard anesthetic circuit that may impede anesthetic induction and recovery with I-653, sevoflurane, isoflurane, and halothane. Partition coefficients for anesthetic circuit components (masks, bellows, bags, airways, and circuit tubes) consistently ranked halothane greate...

journal_title：Anesthesia and analgesia

authors： Targ AG,Yasuda N,Eger EI 2nd

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Topical anesthesia of the upper airway is often recommended when difficulty in airway management is anticipated. There are published reports, however, of administration of topical anesthesia resulting in complete loss of airway control. Adverse effects are mostly attributed to interference with involuntary p...

journal_title：Anesthesia and analgesia

authors： Maxwell MJ,English JD,Moppett IK,McGlashan JA,Norris AM

更新日期：2012-04-01 00:00:00

abstract：:Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia with or without signs and symptoms. Such myocardial injury is common, silent, and strongly associated with mortality. MINS is usually asymptomatic and only detect...

journal_title：Anesthesia and analgesia

authors： Ruetzler K,Khanna AK,Sessler DI

更新日期：2020-07-01 00:00:00

abstract：:The fatal/anesthetic ratio (FAR) in 44 swine weighing 32.6 +/- 0.7 kg (SEM) was determined. Fatal anesthetic concentration (the numerator for FAR) was defined as the end-tidal concentration at which the pig lived at least 10 min, during experiments that involved step increments in anesthetic concentrations. Previously...

journal_title：Anesthesia and analgesia

authors： Roberts SL,Gilbert M,Tinker JH

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:A decline in emergency surgical airway procedures in recent years has resulted in a decreased exposure to cricothyrotomy. Consequently, residents have very little experience or confidence in performing this intervention. In this study, we compared cricothyrotomy skills acquired on a simple inexpensive model ...

journal_title：Anesthesia and analgesia

authors： Friedman Z,You-Ten KE,Bould MD,Naik V

更新日期：2008-11-01 00:00:00

abstract：UNLABELLED:The calcium channel blocker nifedipine has analgesic properties that are enhanced by nicotine. Although it is not known how this analgesic state might affect the awareness of anginal pain and impending myocardial infraction, recent studies have shown an increased mortality associated with the use of large do...

journal_title：Anesthesia and analgesia

authors： Hunt TE,Wu WH,Zbuzek VK

更新日期：1998-11-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression. However, its use is associated with significant posttreatment cognitive impairment. Magnetic seizure therapy (MST) was developed as an alternative therapy that could reduce postseizure side effects through the induction of more "foc...

journal_title：Anesthesia and analgesia

authors： White PF,Amos Q,Zhang Y,Stool L,Husain MM,Thornton L,Downing M,McClintock S,Lisanby SH

更新日期：2006-07-01 00:00:00

abstract：:Neuraxial anesthesia may improve perioperative outcomes when compared to general anesthesia; however, this is controversial. We performed a systematic review and meta-analysis using randomized controlled trials and population-based observational studies identified in MEDLINE, PubMed, and EMBASE from 2010 to May 31, 20...

journal_title：Anesthesia and analgesia

authors： Smith LM,Cozowicz C,Uda Y,Memtsoudis SG,Barrington MJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:There is a pronounced learning curve for the technique of ultrasound-guided regional anesthesia. Practicing with a simulator model has been shown to speed the acquisition of these skills for various ultrasound-guided procedures. However, commercial models for ultrasound-guided regional anesthesia may be too ...

journal_title：Anesthesia and analgesia

authors： Liu Y,Glass NL,Power RW

更新日期：2010-04-01 00:00:00

abstract：:Spontaneous ventilation may offer advantages over controlled mechanical ventilation (CMV), but increase in work of breathing may diminish its usefulness. During general anesthesia, respiratory depression and increased work of breathing often preclude spontaneous ventilation, and patients then receive CMV. We compared ...

journal_title：Anesthesia and analgesia

authors： Christie JM,Smith RA

更新日期：1992-08-01 00:00:00

abstract：:Patient-reported outcomes (PROs) are measures of health status that come directly from the patient. PROs are an underutilized tool in the perioperative setting. Enhanced recovery pathways (ERPs) have primarily focused on traditional measures of health care quality such as complications and hospital length of stay. The...

journal_title：Anesthesia and analgesia

authors： Abola RE,Bennett-Guerrero E,Kent ML,Feldman LS,Fiore JF Jr,Shaw AD,Thacker JKM,Gan TJ,Miller TE,Hedrick TL,McEvoy MD,Mythen MG,Bergamaschi R,Gupta R,Holubar SD,Senagore AJ,Wischmeyer PE,Carli F,Evans DC,Guilbert S,

更新日期：2018-06-01 00:00:00

abstract：:Multiple pharmaceutical products contain excipients, or additive chemicals, to improve stability, bioavailability, antimicrobial activity, or palatability. Two of the most common excipients are propylene glycol and parabens. We report the successful anesthetic management of a patient with idiosyncratic reactions to pr...

journal_title：Anesthesia and analgesia

authors： Farber MK,Angelo TE,Castells M,Tsen LC

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Severe pain has been linked to depression, which raises the question of whether epidural analgesia (EDA) during childbirth is associated with a reduced risk of postpartum depression (PPD). This association has been explored previously, but the studies were restricted by small sample sizes and the inability t...

journal_title：Anesthesia and analgesia

authors： Eckerdal P,Kollia N,Karlsson L,Skoog-Svanberg A,Wikström AK,Högberg U,Skalkidou A

更新日期：2020-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the influence of the volume of methylene blue-local anesthetic on the spread of the injectate along the costal pleura. Twenty patients undergoing elective thoracotomy were studied. Twelve patients received intercostal nerve injection with 10 mL of 0.5% bupivacaine with methyle...

journal_title：Anesthesia and analgesia

authors： Moorthy SS,Dierdorf SF,Yaw PB

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Chronic pain is one of the most common complaints in patients with human immunodeficiency virus (HIV)-associated sensory neuropathy. Ryanodine receptor (RyR) and mitochondrial oxidative stress are involved in neuropathic pain induced by nerve injury. Here, we investigated the role of RyR and mitochondrial su...

journal_title：Anesthesia and analgesia

authors： Godai K,Takahashi K,Kashiwagi Y,Liu CH,Yi H,Liu S,Dong C,Lubarsky DA,Hao S

更新日期：2019-07-01 00:00:00

abstract：:The cardiovascular responses of aortic cross-clamping and declamping with normal and high ventricular filling pressures were compared during epidural and nitrous oxide-morphine anesthesia in 32 male patients undergoing reconstructive aortic surgery. The patients were divided into four groups. Groups I and II had lumba...

journal_title：Anesthesia and analgesia

authors： Lunn JK,Dannemiller FJ,Stanley TH

更新日期：1979-09-01 00:00:00

abstract：:It has been proposed that propofol has antiemetic effects even in nonsedative doses. The aim of this study was to investigate whether propofol influences vomiting induced by the dopamine agonist apomorphine. Ten healthy male volunteers received apomorphine infusion (1 mg/min) until vomiting was induced on four differe...

journal_title：Anesthesia and analgesia

authors： Hvarfner A,Hammas B,Thörn SE,Wattwil M

更新日期：1995-05-01 00:00:00

abstract：UNLABELLED:The sciatic nerve (SN) originates from the L4-S3 roots in the form of two nerve trunks: the tibial nerve (TN) and the common peroneal nerve (CPN). The TN and CPN are encompassed by a single epineural sheath and eventually separate (divide) in the popliteal fossa. This division of the SN occurs at a variable ...

journal_title：Anesthesia and analgesia

authors： Vloka JD,Hadzić A,April E,Thys DM

更新日期：2001-01-01 00:00:00

abstract：:The antagonism of a pancuronium-curare (P + C) neuromuscular block was assessed and compared to the antagonism of a pancuronium (P) block. One group of seven patients received P + C (0.024 mg/kg + 0.144 mg/kg); another similar group of seven patients received P (0.07 mg/kg). Both groups were anesthetized with nitrous ...

journal_title：Anesthesia and analgesia

authors： Vitez TS,Difrancesco LV

更新日期：1983-12-01 00:00:00

abstract：:Several federal agencies have recently noted that the United States is in the midst of an unprecedented "opioid epidemic," with an increasing number of opioid-related overdoses and deaths. Providers currently face 3 population-level, public health challenges in providing optimal perioperative pain care: (1) the contin...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Kain ZN

更新日期：2017-11-01 00:00:00

abstract：UNLABELLED:We tested the hypothesis that routine cleaning and autoclaving does not remove protein deposits from reusable laryngeal mask airways (LMAs). All previously used classic and flexible LMAs from a single hospital were tested. Each LMA was hand-washed in an enzymatic solution for 3 min, machine-washed with a dis...

journal_title：Anesthesia and analgesia

authors： Clery G,Brimacombe J,Stone T,Keller C,Curtis S

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:The increasing demand for anesthetic procedures in the gastrointestinal endoscopy area has not been followed by a similar increase in the methods to provide and control sedation and analgesia for these patients. In this study, we evaluated different combinations of propofol and remifentanil, administered thr...

journal_title：Anesthesia and analgesia

authors： Gambús PL,Jensen EW,Jospin M,Borrat X,Martínez Pallí G,Fernández-Candil J,Valencia JF,Barba X,Caminal P,Trocóniz IF

更新日期：2011-02-01 00:00:00

abstract：UNLABELLED:The purpose of this animal investigation was to compare behavioral responses with spinal Fos-like immunoreactivity (FLI) after pre-versus postformalin administration of anesthetic doses of IV ketamine or alfentanil. Preformalin and postformalin injection (1.5% subcutaneously) treatment groups included IV sal...

journal_title：Anesthesia and analgesia

authors： Gilron I,Quirion R,Coderre TJ

更新日期：1999-07-01 00:00:00

abstract：:We investigated the characteristics of hypoxemic fetoplacental vasoconstriction (HFPV) in the dual perfused, single isolated human placental cotyledon. Fetal arterial blood pressures (FAP) were measured in four cotyledons (Group 1) equilibrated with 21% oxygen (O2), 5% carbon dioxide (CO2), and nitrogen (N2) [control]...

journal_title：Anesthesia and analgesia

authors： Ramasubramanian R,Johnson RF,Downing JW,Minzter BH,Paschall RL

更新日期：2006-08-01 00:00:00