Nitrous oxide exposure in the operating room.

Abstract:

:One-hundred and eight-five pairs of gas samples were collected from inspired gas (10 cm behind the head at nose level) and end-tidal gas of persons administering anesthesia in 3 operating rooms during daily routine anesthesia. Mean operating-room N2O concentrations from 22 to 144 ppm (volume/volume [V/V]) were measured by gas chromatography, and large moment-to-moment variations (temporal gradients) were seen in individual operating rooms. Mean end-tidal N2O concentrations from 51 to 114 ppm (V/V) were observed. There were low correlations between inspired and end-tidal N2O concentrations (r values as low as r = 0.35). This poor relationship is presumably due to spatial and temporal gradients of N2O in the operating rooms. We conclude that the temporal and spatial gradients in N2O concentrations within active operating rooms are sufficiently large to invalidate estimation of exposure of anesthetic personnel to N2O from "spot" or "grab" samples collected in the breathing area.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Beynen FM,Knopp TJ,Rehder K

doi

10.1213/00000539-197803000-00012

subject

Has Abstract

pub_date

1978-03-01 00:00:00

pages

216-23

issue

2

eissn

0003-2999

issn

1526-7598

journal_volume

57

pub_type

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