Changes in cerebral blood flow velocity after release of intraoperative tourniquets in humans: a transcranial Doppler study.

Abstract:

:The effect of release of intraoperative thigh tourniquets on velocity of blood flow in the middle cerebral artery was examined in five patients given general anesthesia with controlled ventilation for lower extremity orthopedic procedures using transcranial Doppler sonography. Middle cerebral artery blood flow velocity increased significantly from 52 +/- 6 (SEM) to 82 +/- 24 cm/s (an increase of 58% +/- 13%) within 4 +/- 1 min after tourniquet release and remained significantly elevated for 7 min. A positive linear correlation was found between middle cerebral artery blood flow velocity and PETCO2 on each occasion (0.97 greater than or equal to r greater than or equal to 0.84, 0.001 greater than P greater than 0.0001) after tourniquet deflation. Assuming a linear relationship between flow velocity and flow, these findings suggest that significant increase in cerebral blood flow can occur after intraoperative tourniquet release and that this increase appears to be mostly CO2-dependent.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Hirst RP,Slee TA,Lam AM

doi

10.1213/00000539-199011000-00009

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

503-10

issue

5

eissn

0003-2999

issn

1526-7598

journal_volume

71

pub_type

杂志文章
  • The division of the sciatic nerve in the popliteal fossa: anatomical implications for popliteal nerve blockade.

    abstract:UNLABELLED:The sciatic nerve (SN) originates from the L4-S3 roots in the form of two nerve trunks: the tibial nerve (TN) and the common peroneal nerve (CPN). The TN and CPN are encompassed by a single epineural sheath and eventually separate (divide) in the popliteal fossa. This division of the SN occurs at a variable ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200101000-00041

    authors: Vloka JD,Hadzić A,April E,Thys DM

    更新日期:2001-01-01 00:00:00

  • Anesthetic action of opiates: correlations of lipid solubility and spectral edge.

    abstract::The ability of opiates to be a complete anesthetic has been assessed in animals. These studies have investigated the serum levels of opiate required to produce a decrease in anesthetic requirement for a concomitantly administered inhalation anesthetic. A linear dose-response relation has been observed between opiate s...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Stone DJ,DiFazio CA

    更新日期:1988-07-01 00:00:00

  • Readability, Content, and Quality Assessment of Web-Based Patient Education Materials Addressing Neuraxial Labor Analgesia.

    abstract:BACKGROUND:Studies in a variety of disciplines have shown that the readability of Web-based patient education materials is above that of the sixth grade reading level recommended by the U.S. Department of Health and Human Services. The aim of this study was to evaluate the readability, content, and quality of English- ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/ANE.0000000000000888

    authors: Patel SK,Gordon EJ,Wong CA,Grobman WA,Goucher H,Toledo P

    更新日期:2015-11-01 00:00:00

  • Perioperatively Acquired Weakness.

    abstract:BACKGROUND:Skeletal muscle failure in critical illness (intensive care unit-acquired weakness) is a well-known complication developing early during intensive care unit stay. However, muscle weakness during the perioperative setting has not yet been investigated. METHODS:We performed a subgroup investigation of a prosp...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/ANE.0000000000004068

    authors: Lachmann G,Mörgeli R,Kuenz S,Piper SK,Spies C,Kurpanik M,Weber-Carstens S,Wollersheim T,BIOCOG Consortium.

    更新日期:2020-02-01 00:00:00

  • Effects of Intraoperative Opioid Use on Recurrence-Free and Overall Survival in Patients With Esophageal Adenocarcinoma and Squamous Cell Carcinoma.

    abstract:BACKGROUND:Perioperative opioid use is associated with poor survival in patients with esophageal squamous cell carcinoma. The most common histological type of esophageal cancer in western countries is adenocarcinoma. The objective of this study was to evaluate the association between intraoperative opioid consumption a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000003428

    authors: Du KN,Feng L,Newhouse A,Mehta J,Lasala J,Mena GE,Hofstetter WL,Cata JP

    更新日期:2018-07-01 00:00:00

  • Hemodynamic effects of portal triad clamping with and without pneumoperitoneum: an echocardiographic study.

    abstract::The decrease of cardiac index observed during portal triad clamping (PTC) with and without pneumoperitoneum has been studied only with right heart catheterization. To better understand this decrease of cardiac index, we investigated the balance between the adequacy of preload and the ability of the heart to pump again...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000144592.20499.12

    authors: Decailliot F,Streich B,Heurtematte Y,Duvaldestin P,Cherqui D,Stéphan F

    更新日期:2005-03-01 00:00:00

  • Transesophageal echocardiography in myocardial revascularization: I. Accuracy of intraoperative real-time interpretation.

    abstract::Transesophageal echocardiography (TEE) is increasingly used intraoperatively as a monitor of ventricular function and volume. Despite its increasing use, whether data from TEE monitoring can be interpreted accurately on-line in real-time is unknown. We studied the performance of five community-based, full-time cardiac...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000539-199606000-00006

    authors: Bergquist BD,Leung JM,Bellows WH

    更新日期:1996-06-01 00:00:00

  • Patient state index during a cardiac arrest in the operating room.

    abstract::A 53-yr-old man undergoing laparoscopic cholecystectomy experienced cardiac arrest intraoperatively. Patient state index values decreased to single digits during the cardiac arrest and returned to baseline after successful cardiopulmonary resuscitation. ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000140247.16106.75

    authors: Nguyen NK,Lenkovsky F,Joshi GP

    更新日期:2005-01-01 00:00:00

  • Fentanyl-air-oxygen anesthesia for ligation of patent ductus arteriosus in preterm infants.

    abstract::In 10 premature infants (1123 +/- 263 g), fentanyl citrate (30 to 50 microgram/kg) was used in conjunction with pancuronium (0.1 mg/kg) as the sole anesthetic for transthoracic ligation of patent ductus arteriosus. Ventilation was controlled with air and oxygen in concentrations sufficient to maintain transcutaneous P...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Robinson S,Gregory GA

    更新日期:1981-05-01 00:00:00

  • The discriminant power of simultaneous monitoring of spontaneous electroencephalogram and evoked potentials as a predictor of different clinical states of general anesthesia.

    abstract::Spontaneous or evoked electrical brain activity is increasingly used to monitor general anesthesia. Previous studies investigated the variables from spontaneous electroencephalogram (EEG), acoustic (AEP), or somatosensory evoked potentials (SSEP). But, by monitoring them separately, the available information from simu...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/01.ane.0000237231.73261.92

    authors: Jeleazcov C,Schneider G,Daunderer M,Scheller B,Schüttler J,Schwilden H

    更新日期:2006-10-01 00:00:00

  • R(+)-, Rac-, and S(-)-bupivacaine stereostructure-specifically interact with membrane lipids at cardiotoxically relevant concentrations.

    abstract::It remains questionable whether local anesthetics can interact with membrane lipids at clinically relevant concentrations to show the difference between enantiomers. We compared the effects of bupivacaine stereoisomers on biomimetic membranes containing cardiolipin and cholesterol. Bupivacaine interacted with the memb...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e31823ed410

    authors: Tsuchiya H,Mizogami M

    更新日期:2012-02-01 00:00:00

  • GABA(A) receptor blockade antagonizes the immobilizing action of propofol but not ketamine or isoflurane in a dose-related manner.

    abstract:UNLABELLED:The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the righting reflex. We examined whether the noncompetitive GABA...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000048821.23225.3a

    authors: Sonner JM,Zhang Y,Stabernack C,Abaigar W,Xing Y,Laster MJ

    更新日期:2003-03-01 00:00:00

  • Antinociceptive and neurotoxicologic screening of chronic intrathecal administration of ketorolac tromethamine in the rat.

    abstract:UNLABELLED:Many drugs are tested intrathecally to investigate alternatives to opioids. We aimed to explore the analgesic and possible neurotoxic effects of chronic intrathecally-administered ketorolac tromethamine in rats. Catheters were placed via atlantoaxial interval in 28 Wistar rats under anesthesia of intraperito...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000093226.75543.90

    authors: Korkmaz HA,Maltepe F,Erbayraktar S,Yilmaz O,Güray M,Canda MS,Günerli A,Gökmen N

    更新日期:2004-01-01 00:00:00

  • Migraine with atypical aura in the recovery room: a sometimes complicated diagnosis!

    abstract::Migraine is a frequent neurological pathology. However, the diagnosis can be difficult to establish, especially when it is accompanied with an atypical aura that can be confounded with a stroke. We describe a case of 38-yr-old patient who presented just after general anesthesia with a perioperative acute migraine with...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e31816d145e

    authors: Pianezza A,Barthélémy R,Minville V,Martin F,Faggianelli M

    更新日期:2008-06-01 00:00:00

  • The inhibitory effect of bupivacaine on prostaglandin E(2) (EP(1)) receptor functioning: mechanism of action.

    abstract::Prostaglandin E(2) receptors, subtype EP(1) (PGE(2)EP(1)) have been linked to several physiologic responses, such as fever, inflammation, and mechanical hyperalgesia. Local anesthetics modulate these responses, which may be due to direct interaction of local anesthetics with PGE(2)EP(1) receptor signaling. We sought t...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200109000-00019

    authors: Hönemann CW,Heyse TJ,Möllhoff T,Hahnenkamp K,Berning S,Hinder F,Linck B,Schmitz W,van Aken H

    更新日期:2001-09-01 00:00:00

  • The effect of short-term epidural local anesthetic blockade on urinary levels of substance P in interstitial cystitis.

    abstract:UNLABELLED:We investigated the effect of epidural local anesthetic blockade on urinary substance P levels in five patients suffering from painful flare-ups of interstitial cystitis. Urine was collected in 24-h intervals commencing at the onset of an epidural bolus of 0.25% bupivacaine followed by maintenance epidural i...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/01.ane.0000099362.01312.3a

    authors: Sukiennik A,Carr DB,Bonney I,Marchand JE,Wurm H,Sant GR

    更新日期:2004-03-01 00:00:00

  • Halothane and children: the first quarter century.

    abstract::For the past 25 years, halothane has been the primary anesthetic agent at Children's Hospital, Columbus, Ohio. To confirm our impression that adverse reactions to halothane are rarely a problem in children, we examined the records of 200,311 cases conducted with halothane from June 1, 1958, through May 31, 1983. Life-...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Warner LO,Beach TP,Garvin JP,Warner EJ

    更新日期:1984-09-01 00:00:00

  • A comparison of the laryngeal mask airway ProSeal and the laryngeal tube airway in paralyzed anesthetized adult patients undergoing pressure-controlled ventilation.

    abstract:UNLABELLED:We compared the laryngeal mask airway ProSeal (PLMA) and the laryngeal tube airway (LTA), two new extraglottic airway devices, with respect to: 1) insertion success rates and times, 2) efficacy of seal, 3) ventilatory variables during pressure-controlled ventilation, 4) tidal volume in different head/neck po...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200209000-00045

    authors: Brimacombe J,Keller C,Brimacombe L

    更新日期:2002-09-01 00:00:00

  • Giving toys to children reduces their anxiety about receiving premedication for surgery.

    abstract::Children have increased anxiety during the preoperative period. The administration of oral premedication to children is often met with apprehension, reluctance, or refusal. We sought to determine whether giving a small toy to the children would decrease the anxiety associated with taking oral premedication. This was a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000198332.51475.50

    authors: Golden L,Pagala M,Sukhavasi S,Nagpal D,Ahmad A,Mahanta A

    更新日期:2006-04-01 00:00:00

  • Onset, intensity of blockade and somatosensory evoked potential changes of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine.

    abstract::The onset and intensity of blockade of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine were investigated in a randomized, double-blind study in 26 patients. Control subjects (n = 13) received 20 mL of 1.37% lidocaine (1.5% lidocaine plus 1 mL saline per 10 mL lidocaine) with added 1:200...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Benzon HT,Toleikis JR,Dixit P,Goodman I,Hill JA

    更新日期:1993-02-01 00:00:00

  • Sigma receptor activation does not mediate fentanyl-induced attenuation of muscarinic coronary contraction.

    abstract::Our overall goal was to investigate the mechanism by which fentanyl attenuates acetylcholine-induced contraction in porcine coronary artery. We tested the hypothesis that fentanyl attenuates muscarinic coronary contraction via sigma receptor activation. Left coronary artery vascular rings were isolated from porcine he...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199605000-00016

    authors: Tsuchida H,Schubert A,Estafanous FG,Brum JM,Murray PA

    更新日期:1996-05-01 00:00:00

  • Antinociceptive interaction between spinal clonidine and lidocaine in the rat formalin test: an isobolographic analysis.

    abstract:UNLABELLED:Clinical and basic science studies suggest that spinal alpha-2-adrenergic receptor agonists and local anesthetics produce analgesia, but interaction between alpha-2-adrenergic receptor agonists and local anesthetics in the persistent pain model has not been examined. In the present study, using isobolographi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200103000-00034

    authors: Hao S,Takahata O,Iwasaki H

    更新日期:2001-03-01 00:00:00

  • A comparison of peripheral skin blood flow and temperature during endoscopic thoracic sympathotomy.

    abstract::The assessment of sympathetic denervation to the upper extremities during surgery for hyperhidrosis is essential in predicting postoperative outcome, particularly for endoscopic thoracic chain sympathotomy, a recently described, minimally destructive technique that minimizes postoperative compensatory hyperhidrosis. T...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/01.ANE.0000139934.15659.7F

    authors: Eisenach JH,Pike TL,Wick DE,Dietz NM,Fealey RD,Atkinson JL,Charkoudian N

    更新日期:2005-01-01 00:00:00

  • An analysis of responses to levosimendan in the pulmonary vascular bed of the cat.

    abstract:UNLABELLED:Calcium-sensitizing drugs, such as levosimendan, are a novel class of drug therapy for heart failure. We investigated the hypothesis that levosimendan is a pulmonary vasodepressor mediated through inhibition of phosphodiesterase, adenosine triphosphate (ATP)-dependent potassium channels, or both. We investig...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200206000-00009

    authors: De Witt BJ,Ibrahim IN,Bayer E,Fields AM,Richards TA,Banister RE,Kaye AD

    更新日期:2002-06-01 00:00:00

  • Alterations in spinal, but not cerebral, cerebrospinal fluid Na+ concentrations affect the isoflurane minimum alveolar concentration in rats.

    abstract:BACKGROUND:Previous studies demonstrated that MAC (the minimum alveolar concentration of an inhaled anesthetic that produces immobility in 50% of subjects exposed to noxious stimulation) for halothane directly correlates with the central nervous system concentration of Na+. However, those studies globally altered Na+ c...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000278090.88402.26

    authors: Laster MJ,Zhang Y,Eger EI 2nd,Shnayderman D,Sonner JM

    更新日期:2007-09-01 00:00:00

  • Brain edema, hemorrhagic necrosis volume, and neurological status with rapid infusion of 0.45% saline or 5% dextrose in 0.9% saline after closed head trauma in rats.

    abstract::We previously reported that in rats with closed head trauma (CHT), intravenous (IV) administration of 0.25 mL/g of 5% dextrose solution (D5W) increased blood glucose (G), decreased blood sodium (Na), caused no change in blood osmolality (Osm), increased brain edema (BE), and worsened neurological severity score (NSS) ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199703000-00016

    authors: Gurevich B,Talmor D,Artru AA,Katcko L,Geva D,Gurman G,Shapira Y

    更新日期:1997-03-01 00:00:00

  • The time-dependent effects of midazolam on regional cerebral glucose metabolism in rats.

    abstract:BACKGROUND:Midazolam has hypnotic and sedative activities, which may be mediated by different neuronal structures. We investigated the time course effect of a hypnotic dose of midazolam on conscious motor behavior and on patterns of brain metabolism. METHODS:Loss of nociceptive reflexes and impairment of spontaneous l...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e31816a64a8

    authors: Freo U,Dam M,Ori C

    更新日期:2008-05-01 00:00:00

  • An advanced specialty training program in anesthesiology: a special educational fellowship designed to return community anesthesiologists to clinical practice.

    abstract::We describe a program for community anesthesiologists designed to evaluate clinical skills and provide additional training in the latest technologies in anesthesiology. This educational program was established for previously trained anesthesiologists who require additional training for either remedial purposes or beca...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000220903.33100.15

    authors: Larson CP Jr,Steadman RH

    更新日期:2006-07-01 00:00:00

  • Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells.

    abstract::The effects of commercial and crystalline solutions of chloroprocaine (CP) (1.6 X 10(-3)-0.4 X 10(-3)M) and sodium bisulfite (SB) (0.8 X 10(-3)-0.08 X 10(-3)M) were studied on the multiplication of human neuroblastoma cells. These cells were chosen because of putative neurotoxicity associated with CP; cell multiplicat...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Seravalli E,Lear E

    更新日期:1987-10-01 00:00:00

  • The relationship among carbon dioxide pneumoperitoneum, vasopressin release, and hemodynamic changes.

    abstract:UNLABELLED:We assessed the role of vasopressin (VP) for the hemodynamic response to pneumoperitoneum in pigs. Four groups of anesthetized pigs were investigated. Nine pigs were intraabdominally insufflated with CO2 and eight were intraabdominally insufflated with argon; eight pigs received an i.v. injection of 1 mg/kg ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199908000-00003

    authors: Mann C,Boccara G,Pouzeratte Y,Eliet J,Serradel-Le Gal C,Vergnes C,Bichet DG,Guillon G,Fabre JM,Colson P

    更新日期:1999-08-01 00:00:00