A case of intraplacental choriocarcinoma associated with placental hemangioma.

abstract：:Microscopic pulmonary tumor embolism is difficult to diagnose. Herein is presented the case of a patient who suffered from acute dyspnea and breast cancer on the right side. Two weeks after the breast cancer diagnosis the patient began to experience dyspnea. After 2 weeks of dyspnea, the patient died without an accura...

journal_title：Pathology international

authors： Kawasaki H,Ogura H,Arai Y,Baba S,Kosugi I,Tsutsui Y,Iwashita T

更新日期：2010-03-01 00:00:00

abstract：:The purpose of the present paper was to examine the level of apoptosis and the relationships among apoptosis, apoptosis-associated proteins, and proliferating potential in lymphoma tissues to clarify the characteristics of apoptosis in diffuse large B-cell lymphomas (DLBCL) of the central nervous system (CNS). The for...

journal_title：Pathology international

authors： Arai M,Sasaki A,Saito N,Nakazato Y

更新日期：2005-03-01 00:00:00

abstract：:Many human colorectal adenocarcinoma cell lines have been developed. However, differentiated type colorectal cancer cell lines, particularly, the goblet-cell differentiated type, are scarce. In the present study a novel colorectal adenocarcinoma cell line (designated as COLM-6) with predominant goblet-cell differentia...

journal_title：Pathology international

authors： Yamachika T,Nakanishi H,Yasui K,Ikehara Y,Niwa T,Wanibuchi H,Tatematsu M,Fukushima S

更新日期：2005-09-01 00:00:00

abstract：:Osteosarcoma is one of the neoplasms that may occur following exposure to radiation. A case of osteosarcoma arising in the craniofacial bone with a short latency period of 3 years after radiotherapy for maxillary squamous cell carcinoma is described. A 64-year-old-man underwent right partial maxillectomy and chemoradi...

journal_title：Pathology international

authors： Matsuyama A,Yonemitsu N,Hayashida S,Watanabe K,Sugihara H,Inokuchi A

更新日期：2003-01-01 00:00:00

abstract：:Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare genetic disorder characterized by cutaneous and uterine leiomyomatosis with RCC. This disorder is caused by a germline mutation in the fumarate hydratase (FH) gene, which encodes an important enzyme of the tricarboxylic acid (TCA) cycle. This mutation d...

journal_title：Pathology international

authors： Matsumoto K,Udaka N,Hasumi H,Nakaigawa N,Nagashima Y,Tanaka R,Kato I,Yao M,Furuya M

更新日期：2018-05-24 00:00:00

abstract：:An autopsy case of malignant mesothelioma with asbestosis caused by asbestos exposure for 17 years is reported. Autopsy revealed that mesothelioma spread extensively in all serosal tissues including pleura, pericardium, diaphragm, peritoneum and tunica vaginalis testis. Histopathologically, most of the tumor showed an...

journal_title：Pathology international

authors： Watanabe M,Kimura N,Kato M,Iwami D,Takahashi M,Nagura H

更新日期：1994-10-01 00:00:00

abstract：:An extremely rare case of malignant mesothelioma of the pericardium is reported. The tumor appeared to be the biphasic type of diffuse malignant mesothelioma which present many small to fine lipid droplets in the cytoplasm, particularly that of the epithelial cell, and a positive immunohistochemical reaction with anti...

journal_title：Pathology international

authors： Ohmori T,Arita N,Okada K,Kondo M,Tabei R

更新日期：1995-08-01 00:00:00

abstract：:Multiple injections with a mouse monoclonal anti-rat Thy-1 antibody (five times, at weekly intervals) induced marked glomerular sclerotic lesions which are characterized by adhesion of glomerular capillaries to Bowman's capsule and persistent proteinuria in rats. Abnormal production of type I collagen and increased ac...

journal_title：Pathology international

authors： Yagi M,Yamamoto T,Kato S,Nagano N,Kihara I

更新日期：1998-07-01 00:00:00

abstract：:The roles of Wnt protein in carcinogenesis have been well documented in human cancers. Wls is a key modulator for the secretion of Wnt protein. We previously found that Wls was aberrantly expressed in colorectal carcinomas. Studies have revealed that dysregulation of Wnt signal transduction plays an important role in ...

journal_title：Pathology international

authors： Zhang W,Tao H,Chen X,Sugimura H,Wang J,Zhou P

更新日期：2017-03-01 00:00:00

abstract：:The clinicopathological significance of colonic and small-intestinal phenotypes has hitherto remained unclear in gastric cancers. The purpose of the present study was therefore to examine 86 gastric carcinomas histologically and phenotypically using several phenotypic markers, including colon-specific carbonic anhydra...

journal_title：Pathology international

authors： Mizoshita T,Tsukamoto T,Tanaka H,Takenaka Y,Kato S,Cao X,Joh T,Tatematsu M

更新日期：2005-10-01 00:00:00

abstract：:Multiple myeloma (MM) is a plasma-cell neoplasm that can cause renal disorders. Renal lesions in MM can present with a very rare pathological manifestation involving a specific monoclonal immunoglobulin (Ig). We report the case of a 33-year-old woman who had edema, fatigue, elevated serum creatinine levels, hypoalbumi...

journal_title：Pathology international

authors： Watanabe H,Osawa Y,Goto S,Habuka M,Imai N,Ito Y,Hirose T,Chou T,Ohashi R,Shimizu A,Ehara T,Shimotori T,Narita I

更新日期：2015-01-01 00:00:00

abstract：:Aerobes, including humans, are consistently exposed to oxidative stress by consuming oxygen. The biological significance of oxidative stress via reactive oxygen and nitrogen species consists of two stages: reversible redox regulation and irreversible oxidative molecular damage, which are sometimes intermingled. During...

journal_title：Pathology international

authors： Toyokuni S,Akatsuka S

更新日期：2007-08-01 00:00:00

abstract：:One hundred and fifteen patients with chronic hepatitis C were administered interferon (IFN) and classed into two groups: (i) complete responders (CR), HCV-RNA continuously negative 1 year after treatment; and (ii) non-responders (NR), positive 1 year after treatment. Multivariate analysis comprised eight variables: a...

journal_title：Pathology international

authors： Kim SR,Hayashi Y,Yoon S,Taniguchi M,Yang MK,Kim KI,Kim MM,Saeki K,Nukata I,Imoto S

更新日期：1998-03-01 00:00:00

abstract：:A unique case of duodenal stromal tumor in a 51-year-old man is reported. The tumor histologically showed spindle cell proliferation and numerous eosinophilic globules. Most globules were composed of tangled 45 nm thick fibrils, which were ultrastructurally identical to 'skeinoid fibers'. The presence of glycogen gran...

journal_title：Pathology international

authors： Matsukuma S,Doi M,Suzuki M,Ikegawa K,Sato K,Kuwabara N

更新日期：1997-11-01 00:00:00

abstract：:CpG island methylator phenotype (CIMP) is a recently described subset of colorectal cancers (CRC) with widespread methylation of multiple promoter CpG islands. But the prognostic implication of CIMP in CRC has not been clarified. Thus, the aim of the present study was to differentiate the unique characteristics of CIM...

journal_title：Pathology international

authors： Lee S,Cho NY,Choi M,Yoo EJ,Kim JH,Kang GH

更新日期：2008-02-01 00:00:00

abstract：:A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed. A small pleural nodule was incidentally found during a thoracic operation in a 54-year-old woman with esophageal cancer. The patient had no history of exposure to asbestos, and ...

journal_title：Pathology international

authors： Minato H,Nojima T,Kurose N,Kinoshita E

更新日期：2009-08-01 00:00:00

abstract：:A case of lymphoid hyperplasia arising in the large intestine of a 54-year-old woman is described. Barium enema X-ray and colonoscopic examination revealed multiple small polyps in the right side of the colon. Pathological findings from forceps biopsy revealed similar features to a mucosa-associated lymphoid tissue (M...

journal_title：Pathology international

authors： Nagaoka S,Bandoh T,Takemura T

更新日期：2000-09-01 00:00:00

abstract：:Immunohistochemical and clinicopathological features of 58 gastrointestinal stromal tumors (GIST) were studied. One occurred in the esophagus, 41 in the stomach, nine in the small intestine, and seven in the large intestine. By using indirect immunoperoxidase staining for Cajal cell markers (c-kit protein and CD34), s...

journal_title：Pathology international

authors： Tazawa K,Tsukada K,Makuuchi H,Tsutsumi Y

更新日期：1999-09-01 00:00:00

abstract：:The overexpression of p53 protein and the Ki67 proliferative index was evaluated in 96 hepatocellular carcinomas (HCC), 67 in cirrhotic livers and 29 in non-cirrhotic ones, and in 13 non-carcinomatous lesions, all surgically resected from Italian patients. Overexpression of p53 was detected only in carcinomatous lesio...

journal_title：Pathology international

authors： D'Errico A,Grigioni WF,Fiorentino M,Baccarini P,Grazi GL,Mancini AM

更新日期：1994-09-01 00:00:00

abstract：:A case of small cell carcinoma arising in the outer urethral orifice is presented. The resected tumor showed a proliferation of small round or fusiform neoplastic cells in the submucosa. Tumor cells were arranged in sheets or a trabecular manner and possessed markedly hyperchromatic nuclei with a high N:C ratio, close...

journal_title：Pathology international

authors： Fukuda T,Kamishima T,Saito T,Itoh S,Suzuki T

更新日期：1997-07-01 00:00:00

abstract：:A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobect...

journal_title：Pathology international

authors： Zhang Z,Nonaka H,Nagayama T,Hatori T,Ihara F,Zhang L,Akima M,Shiba T

更新日期：2001-12-01 00:00:00

abstract：:YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...

journal_title：Pathology international

authors： Fukuda T,Kamishima T,Kakihara T,Yamada T,Matsumoto K,Uchiyama M,Suzuki T

更新日期：1997-08-01 00:00:00

abstract：:Sarcomatoid carcinoma of the pancreas is an uncommon neoplasm. The immunohistochemical characteristics of this unique type of pancreatic tumor were studied. Histologically, there was diffuse proliferation of atypical spindle cells that had hyperchromatic, short, spindle-shaped nuclei and pale cytoplasm. A few tiny foc...

journal_title：Pathology international

authors： Higashi M,Takao S,Sato E

更新日期：1999-05-01 00:00:00

abstract：:A quantitative model was devised for the purpose of evaluating interobserver agreement in the judgment of the nuclear atypia score of cancer cells in protocol studies. In this model, the mean nuclear atypia score (mu) among observers was considered to approximate the 'true' nuclear atypia score of the tumor, and with ...

journal_title：Pathology international

authors： Tsuda H,Akiyama F,Kurosumi M,Sakamoto G,Watanabe T

更新日期：2000-02-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy is an unusual malignancy-related respiratory complication characterized by multiple microthrombi and intimal myofibroblast proliferation. Its clinical manifestation is subacute respiratory failure with pulmonary hypertension. Herein is reported a case of pulmonary tumor throm...

journal_title：Pathology international

authors： Sakashita N,Yokose C,Fujii K,Matsumoto M,Ohnishi K,Takeya M

更新日期：2007-06-01 00:00:00

abstract：:We report a case of ALK-positive renal cell carcinoma coincident with Hodgkin lymphoma. The patient was a 19 year-old-girl without sickle cell trait. The right renal tumor was discovered concomitantly with Hodgkin lymphoma (HL). After chemotherapy for HL, right nephrectomy was performed. Microscopically, the tumor sho...

journal_title：Pathology international

authors： Oyama Y,Nishida H,Kusaba T,Kadowaki H,Arakane M,Daa T,Watanabe D,Akita Y,Sato F,Mimata H,Yokoyama S

更新日期：2017-12-01 00:00:00

abstract：:Elderly patients with Epstein-Barr virus (EBV) infection are at increased risk for developing B-cell lymphoproliferative disorder (B-LPD) due to immunosenescence. Here, we describe a case of a 75-year-old man who developed an EBV-positive (EBV+) mucocutaneous ulcer (EBVMCU) in the gingiva with spontaneous regression. ...

journal_title：Pathology international

authors： Daroontum T,Kohno K,Inaguma Y,Okamoto A,Okamoto M,Kimura Y,Nagahama M,Sakakibara A,Satou A,Nakamura S

更新日期：2019-01-01 00:00:00

abstract：:A report of a 65-year-old male with a tumor arising from synovial tissue of the radio-ulnar joint. On magnetic resonance imaging, the tumor was demonstrated as a heterogeneous and lobulated mass with a low signal intensity both in T1- and T2-weighted images. Histological findings of the tumor were identical to those o...

journal_title：Pathology international

authors： Misawa A,Okada K,Hirano Y,Sageshima M

更新日期：1999-12-01 00:00:00

abstract：:The first tumor, node, metastasis (TNM) classification for stomach tumors was published in the second edition of the TNM classification of malignant tumors in 1974 and was followed by additional editions up to the seventh edition published in 2010. In the Buffalo Meeting 2008 a harmonization between the Eastern (Japan...

journal_title：Pathology international

authors： Wittekind C

更新日期：2015-08-01 00:00:00

abstract：:Amyloidosis refers to a group of diseases with amyloid fibrils deposited in various organs and is classified into more than 30 diseases in humans based on the kind of amyloid protein. In order to elucidate the molecular pathogenesis of human amyloidosis, we studied the molecular mechanism of amyloid fibril formation i...

journal_title：Pathology international

authors： Naiki H,Okoshi T,Ozawa D,Yamaguchi I,Hasegawa K

更新日期：2016-04-01 00:00:00