Abstract:
:A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobectomy was performed. The tumor recurred several months after surgery and the patient died on 4 June 1999. At autopsy, both a major tumor mass with extensive involvement, located in the surgical margin, and a small mass located in S7 were discovered. Microscopically, the major tumor was diagnosed as adenosquamous carcinoma and the small one in S7 as hepatocellular carcinoma. To our knowledge, this is the first case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver. The pathological findings support the hypothesis that this tumor developed as a squamous transformation of adenocarcinoma.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Zhang Z,Nonaka H,Nagayama T,Hatori T,Ihara F,Zhang L,Akima M,Shiba Tdoi
10.1046/j.1440-1827.2001.01302.xsubject
Has Abstractpub_date
2001-12-01 00:00:00pages
961-4issue
12eissn
1320-5463issn
1440-1827pii
1302journal_volume
51pub_type
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