Abstract:
:This is the first report of segmental arterial mediolysis (SAM) accompanied with polyarteritis nodosa (PN), and manifesting aneurysms of the renal arteries. A 73-year-old woman was admitted to hospital because of a high fever. Laboratory tests showed leukocytosis with increased CRP level in the serum. Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) and proteinase 3 (PR3)-ANCA were negative. There were no signs indicating infection or malignancy. After admission renal function rapidly deteriorated. Treatment was then started with daily oral prednisolone and hemodialysis. On the 40th day of hospitalization the patient suddenly became comatose. Cranial CT showed a subarachnoid hemorrhage. The patient died and an autopsy was performed. The pathological findings showed necrotizing vasculitis of the small arteries in various organs, but not associated with that of arterioles or renal glomerular lesions, indicating PN. Unexpectedly, the segmental arteries of the bilateral kidneys showed vascular lesions of dissecting aneurysms, indicating SAM. This case indicates that SAM is one of the causes of aneurysms in PN and is clinically important when the clinical course of PN patients rapidly advances.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Soga Y,Nose M,Arita N,Komori H,Miyazaki T,Maeda T,Furuya Kdoi
10.1111/j.1440-1827.2009.02351.xsubject
Has Abstractpub_date
2009-03-01 00:00:00pages
197-200issue
3eissn
1320-5463issn
1440-1827pii
PIN2351journal_volume
59pub_type
杂志文章abstract::YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1997.tb04533.x
更新日期:1997-08-01 00:00:00
abstract::The Association of Directors of Anatomic and Surgical Pathology have developed recommendations for the surgical pathology reporting of common malignant tumors. The recommendations for carcinomas of the urinary bladder are reported herein. ...
journal_title:Pathology international
pub_type: 指南,杂志文章,实务指引
doi:10.1111/j.1440-1827.1997.tb04502.x
更新日期:1997-05-01 00:00:00
abstract::The distribution of carcinoembryonic antigen (CEA) in human gastric adenocarcinoma cell lines (HPE-GAC-3 cells and HPE-GAC-2 cells) was determined immunohistochemically by indirect peroxidase-labeled antibody method at the light and electron microscopic levels. In GAC-3 cells that proliferated as non-adherent single c...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1994.tb01724.x
更新日期:1994-08-01 00:00:00
abstract::Ovarian non-gestational choriocarcinomas co-existing with adenocarcinoma are extremely rare and have been reported as epithelial ovarian carcinomas of a "non-germ cell origin" with "choriocarcinomatous differentiation". Although the cellular origin of non-gestational choriocarcinoma may be post-meiotic ovarian germ ce...
journal_title:Pathology international
pub_type:
doi:10.1111/pin.12445
更新日期:2016-09-01 00:00:00
abstract::One hundred and fifteen patients with chronic hepatitis C were administered interferon (IFN) and classed into two groups: (i) complete responders (CR), HCV-RNA continuously negative 1 year after treatment; and (ii) non-responders (NR), positive 1 year after treatment. Multivariate analysis comprised eight variables: a...
journal_title:Pathology international
pub_type: 临床试验,杂志文章
doi:10.1111/j.1440-1827.1998.tb03895.x
更新日期:1998-03-01 00:00:00
abstract::Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare, recently recognized neoplasm occurring predominantly in the subcutaneous tissue of the lower limbs of adults. We report a case of PHAT in an 83-year-old woman who presented with a 5.0 x 5.0 x 2.0 cm mass in the soft part of her left thigh. Histologically, the...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2002.01406.x
更新日期:2002-10-01 00:00:00
abstract::Matrix metalloproteinases (MMP) play a role in a wide range of tumorigenesis, including early carcinogenesis events, tumor growth and tumor invasion and metastasis. Given that the ability of tumor cells to infiltrate and disseminate widely is what makes the tumors malignant, a role of MMP in cell migration during this...
journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1046/j.1440-1827.2002.01343.x
更新日期:2002-04-01 00:00:00
abstract::Adenomyoma of the small intestine is a rare tumor-like lesion composed of exocrine-type ducts and hypertrophic smooth muscle. We describe two cases of adenomyoma of the small intestine. One was an ileal adenomyoma that presented with intussusception occurring in a 7-month-old boy. The other was a jejunal adenomyoma fo...
journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1046/j.1440-1827.2003.01435.x
更新日期:2003-02-01 00:00:00
abstract::We have previously reported the frequent occurrence of bile duct invasion by liver metastases from colorectal cancer. We found that patients with macroscopic intrabiliary cancer growth survive longer after hepatectomy than those without this feature. In the present study, we analyzed the clinicopathological features o...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2002.01382.x
更新日期:2002-08-01 00:00:00
abstract::Morphologic features and neoplastic potentials of bile duct adenoma (BDA) and von Meyenburg complex (VMC)-like duct arising in chronic liver disease were unknown. Thirty-five BDAs and 12 VMC-like duct lesions were observed in 39 cases with chronic liver disease. BDAs were divided into the EMA-cytoplasmic type (n = 14)...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12209
更新日期:2014-11-01 00:00:00
abstract::We investigated the diagnostic and prognostic value of p53 expression and proliferative activity, as indicated by the Ki-67, in endoscopic biopsy specimens. Specimens were immunologically stained with p53 and MIB-1 (Ki-67), and the MIB-1/Ki-67 labeling index (LI) was calculated. Classification of adenomas was based on...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2003.01482.x
更新日期:2003-06-01 00:00:00
abstract::Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1996.tb03660.x
更新日期:1996-08-01 00:00:00
abstract::Microscopic colitis (MC), encompassing collagenous colitis and lymphocytic colitis, is featured by chronic diarrhea, normal-looking endoscopic findings and unique microscopic appearance. After reviewing biopsied nonspecific colitis, we propose the third type of MC: colitis nucleomigrans (CN). Histopathological criteri...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12996
更新日期:2020-10-01 00:00:00
abstract::We report a very rare case of combined thymic carcinomas: undifferentiated thymic carcinoma coexisting with type AB thymoma. The precise mechanism underlying the coexistence of these tumors remains unknown. Therefore, we used clonality analysis to ascertain whether the two tumors were clonally related. A 63-year-old w...
journal_title:Pathology international
pub_type:
doi:10.1111/pin.12426
更新日期:2016-07-01 00:00:00
abstract::An unusual case of cystic renal cell carcinoma in a 70-year-old Japanese male is reported. He had had a simple renal cyst removed 1 year ago. On presentation the right kidney was surrounded by multiple translucent cysts, which varied in size from 1 to 50 mm. The cyst walls were lined by single-layered cuboidal epithel...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1998.tb03960.x
更新日期:1998-08-01 00:00:00
abstract::Angiomyolipoma (AML) is a mixed mesenchymal tumor belonging to the family of perivascular epithelioid cell tumors. Concurrent development of AML and adult renal cell carcinoma (RCC) is very rare. Herein is presented a unique case in which RCC arose within a previously detected AML tumor mass. A 40-year-old woman had b...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2006.02075.x
更新日期:2007-03-01 00:00:00
abstract::Mitral annular calcification (MAC) is a generally asymptomatic abnormality found commonly in aged hearts. Some clinical studies have suggested that MAC should be considered an independent risk factor for stroke; however, whether the abnormality is indeed a risk factor remains controversial. We report a case in which d...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2012.02826.x
更新日期:2012-07-01 00:00:00
abstract::A mixed tumor with apocrine differentiation seen in the external auditory canal of a 39 year old male is reported. The well demarcated polypoid tumor showed proliferation of elongated gland-like or duct-like structures lined by two rows of epithelial cells, occasionally accompanied by foci of keratinization. There wer...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1994.tb02589.x
更新日期:1994-01-01 00:00:00
abstract::We have reported that the function of histamine and its receptors (HRs) has a close relationship with the development of nonalcoholic fatty liver disease (NAFLD). However, much less is known regarding its pathogenic and molecular mechanism(s), including the early stage of hepatic and intestinal function for lipid and ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12423
更新日期:2016-07-01 00:00:00
abstract::The DNA ploidy pattern of nine hepatoblastomas and three normal liver specimens was investigated by flow cytometry. Areas of unlike differentiation in the same tumor were investigated separately. Normal liver tissue and the fetal subtype were always diploid. Aneuploidy was found in the embryonal subtype. The one case ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1995.tb03492.x
更新日期:1995-07-01 00:00:00
abstract::We report a case of small intestinal type adenocarcinoma arising in retroperitoneal mature cystic teratoma in a young male. The patient initially experienced intermittent abdominal pain, and radiographic workup revealed an encapsulated retroperitoneal mass. A laparotomy was performed and the resected specimen represen...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2010.02582.x
更新日期:2010-10-01 00:00:00
abstract::A case of a rare pancreatic tumor, duct-acinar-islet cell tumor is presented. The tumor was incidentally found in the pancreatic body on computed tomography of a 21 year old male suffering from mumps. It was well demarcated from surrounding pancreas, and spherical in shape, measured 2.5 cm in diameter. Histologic and ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1995.tb03520.x
更新日期:1995-09-01 00:00:00
abstract::A case of primary leiomyosarcoma of a thoracic vertebra associated with a compression fracture in a 75-year-old woman was preoperatively thought to be granulation tissue. Surgical decompression was performed and the histological and immunohistochemical studies established the diagnosis of leiomyosarcoma. Based on the ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2004.01582.x
更新日期:2004-01-01 00:00:00
abstract::The protective effect of Brazilian propolis and its extract Artepillin C against ferric nitrilotriacetate (Fe-NTA)-induced renal lipid peroxidation and carcinogenesis was studied in male ddY mice. Fe-NTA-induced renal lipid peroxidation leads to a high incidence of renal cell carcinoma (RCC) in mice. Administration of...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2000.01097.x
更新日期:2000-09-01 00:00:00
abstract::Microwave cell death (MCD) is unique in that microscopic morphology and antigenicity are well preserved, while enzymatic activity is lost. The aim of the present study was to carry out DNA electrophoresis, polymerase chain reaction (PCR) amplification and terminal deoxynucleotidyl transferase-mediated dUTP nick end-la...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2009.02368.x
更新日期:2009-05-01 00:00:00
abstract::It has been reported that N-myc downstream regulated gene 1 (NDRG1) is related to the prognosis of non-small cell lung cancer (NSCLC), and associated with c-Myc degradation in NSCLC cell lines. However, the relationship of NDRG1 to prognosis or c-Myc expression in lung adenocarcinoma has not been well clarified. The p...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12644
更新日期:2018-04-01 00:00:00
abstract::A surgical case of inflammatory myofibroblastic tumor arising in the uterine corpus and exhibiting prominent myxoid change of the stroma is reported. The patient was a 63-year-old woman with a large tumor mass that filled the uterine cavity and measured 11 cm in maximal dimension. The tumor had a gelatinous appearance...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2006.02018.x
更新日期:2006-10-01 00:00:00
abstract::Bronchiolitis obliterans (BO) is generally believed to be a marker of pulmonary manifestation of graft-versus-host disease (GVHD) in patients who have undergone bone marrow transplantation for hematological malignancy. Pulmonary manifestations reported as GVHD (other than BO) include lymphocytic bronchiolitis with cel...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2009.02492.x
更新日期:2010-02-01 00:00:00
abstract::The relationship between the mutation of the p53 gene and the expression of the p53 protein and the Ki-67 antigen has been investigated in 115 cases with non-Hodgkin's lymphoma, using the immunohistochemical double staining technique, single-strand conformational polymorphism and DNA sequencing methods. Eighteen cases...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1996.tb03588.x
更新日期:1996-02-01 00:00:00
abstract::In 2004, two groups reported somatic mutations in the gene for the epidermal growth factor receptor (EGFR) in patients with non-small cell lung cancer (NSCLC), which were highly correlated with the clinical response to the anticancer drug, gefitinib. Since then, a tremendous amount of knowledge has accumulated, and sh...
journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1111/j.1440-1827.2007.02098.x
更新日期:2007-05-01 00:00:00