Aneurysms of the renal arteries associated with segmental arterial mediolysis in a case of polyarteritis nodosa.

Abstract:

:This is the first report of segmental arterial mediolysis (SAM) accompanied with polyarteritis nodosa (PN), and manifesting aneurysms of the renal arteries. A 73-year-old woman was admitted to hospital because of a high fever. Laboratory tests showed leukocytosis with increased CRP level in the serum. Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) and proteinase 3 (PR3)-ANCA were negative. There were no signs indicating infection or malignancy. After admission renal function rapidly deteriorated. Treatment was then started with daily oral prednisolone and hemodialysis. On the 40th day of hospitalization the patient suddenly became comatose. Cranial CT showed a subarachnoid hemorrhage. The patient died and an autopsy was performed. The pathological findings showed necrotizing vasculitis of the small arteries in various organs, but not associated with that of arterioles or renal glomerular lesions, indicating PN. Unexpectedly, the segmental arteries of the bilateral kidneys showed vascular lesions of dissecting aneurysms, indicating SAM. This case indicates that SAM is one of the causes of aneurysms in PN and is clinically important when the clinical course of PN patients rapidly advances.

journal_name

Pathol Int

journal_title

Pathology international

authors

Soga Y,Nose M,Arita N,Komori H,Miyazaki T,Maeda T,Furuya K

doi

10.1111/j.1440-1827.2009.02351.x

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

197-200

issue

3

eissn

1320-5463

issn

1440-1827

pii

PIN2351

journal_volume

59

pub_type

杂志文章
  • Reactivity of antibody YU-311 in formalin-fixed, paraffin-embedded specimens of normal organs, non-hematopoietic tumors, and mast cell tumors.

    abstract::YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1997.tb04533.x

    authors: Fukuda T,Kamishima T,Kakihara T,Yamada T,Matsumoto K,Uchiyama M,Suzuki T

    更新日期:1997-08-01 00:00:00

  • Recommendations for the reporting of urinary bladder specimens containing bladder neoplasms. Association of Directors of Anatomic and Surgical Pathology.

    abstract::The Association of Directors of Anatomic and Surgical Pathology have developed recommendations for the surgical pathology reporting of common malignant tumors. The recommendations for carcinomas of the urinary bladder are reported herein. ...

    journal_title:Pathology international

    pub_type: 指南,杂志文章,实务指引

    doi:10.1111/j.1440-1827.1997.tb04502.x

    authors:

    更新日期:1997-05-01 00:00:00

  • Immunoelectron microscopic localization of carcinoembryonic antigen in gastric adenocarcinoma cell lines.

    abstract::The distribution of carcinoembryonic antigen (CEA) in human gastric adenocarcinoma cell lines (HPE-GAC-3 cells and HPE-GAC-2 cells) was determined immunohistochemically by indirect peroxidase-labeled antibody method at the light and electron microscopic levels. In GAC-3 cells that proliferated as non-adherent single c...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1994.tb01724.x

    authors: Ohiwa K,Harada T,Morikawa S,Nakamura T

    更新日期:1994-08-01 00:00:00

  • Ovarian nongestational choriocarcinoma and associated adenocarcinoma with the same germ cell origin determined by a molecular genetic approach: A case report.

    abstract::Ovarian non-gestational choriocarcinomas co-existing with adenocarcinoma are extremely rare and have been reported as epithelial ovarian carcinomas of a "non-germ cell origin" with "choriocarcinomatous differentiation". Although the cellular origin of non-gestational choriocarcinoma may be post-meiotic ovarian germ ce...

    journal_title:Pathology international

    pub_type:

    doi:10.1111/pin.12445

    authors: Koyanagi T,Fujiwara H,Usui H,Ariga H,Machida S,Takei Y,Saga Y,Shozu M,Fukushima N,Niki T,Matsubara S,Suzuki M

    更新日期:2016-09-01 00:00:00

  • Prediction of efficacy of interferon treatment of chronic hepatitis C by multivariate analysis and a new classification.

    abstract::One hundred and fifteen patients with chronic hepatitis C were administered interferon (IFN) and classed into two groups: (i) complete responders (CR), HCV-RNA continuously negative 1 year after treatment; and (ii) non-responders (NR), positive 1 year after treatment. Multivariate analysis comprised eight variables: a...

    journal_title:Pathology international

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1827.1998.tb03895.x

    authors: Kim SR,Hayashi Y,Yoon S,Taniguchi M,Yang MK,Kim KI,Kim MM,Saeki K,Nukata I,Imoto S

    更新日期:1998-03-01 00:00:00

  • Pleomorphic hyalinizing angiectatic tumor of soft parts: a case report and literature review.

    abstract::Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare, recently recognized neoplasm occurring predominantly in the subcutaneous tissue of the lower limbs of adults. We report a case of PHAT in an 83-year-old woman who presented with a 5.0 x 5.0 x 2.0 cm mass in the soft part of her left thigh. Histologically, the...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2002.01406.x

    authors: Matsumoto K,Yamamoto T

    更新日期:2002-10-01 00:00:00

  • Matrix metalloproteinases in tumor invasion: role for cell migration.

    abstract::Matrix metalloproteinases (MMP) play a role in a wide range of tumorigenesis, including early carcinogenesis events, tumor growth and tumor invasion and metastasis. Given that the ability of tumor cells to infiltrate and disseminate widely is what makes the tumors malignant, a role of MMP in cell migration during this...

    journal_title:Pathology international

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1827.2002.01343.x

    authors: Nabeshima K,Inoue T,Shimao Y,Sameshima T

    更新日期:2002-04-01 00:00:00

  • Adenomyoma of the small intestine: report of two cases and review of the literature.

    abstract::Adenomyoma of the small intestine is a rare tumor-like lesion composed of exocrine-type ducts and hypertrophic smooth muscle. We describe two cases of adenomyoma of the small intestine. One was an ileal adenomyoma that presented with intussusception occurring in a 7-month-old boy. The other was a jejunal adenomyoma fo...

    journal_title:Pathology international

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1827.2003.01435.x

    authors: Park HS,Lee SO,Lee JM,Kang MJ,Lee DG,Chung MJ

    更新日期:2003-02-01 00:00:00

  • Less aggressive features of colorectal cancer with liver metastases showing macroscopic intrabiliary extension.

    abstract::We have previously reported the frequent occurrence of bile duct invasion by liver metastases from colorectal cancer. We found that patients with macroscopic intrabiliary cancer growth survive longer after hepatectomy than those without this feature. In the present study, we analyzed the clinicopathological features o...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2002.01382.x

    authors: Kubo M,Sakamoto M,Fukushima N,Yachida S,Nakanishi Y,Shimoda T,Yamamoto J,Moriya Y,Hirohashi S

    更新日期:2002-08-01 00:00:00

  • Bile duct adenoma and von Meyenburg complex-like duct arising in hepatitis and cirrhosis: pathogenesis and histological characteristics.

    abstract::Morphologic features and neoplastic potentials of bile duct adenoma (BDA) and von Meyenburg complex (VMC)-like duct arising in chronic liver disease were unknown. Thirty-five BDAs and 12 VMC-like duct lesions were observed in 39 cases with chronic liver disease. BDAs were divided into the EMA-cytoplasmic type (n = 14)...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12209

    authors: Aishima S,Tanaka Y,Kubo Y,Shirabe K,Maehara Y,Oda Y

    更新日期:2014-11-01 00:00:00

  • Usefulness of endoscopic biopsy using immunostaining of p53 and Ki-67 in tumors of the ampulla of Vater.

    abstract::We investigated the diagnostic and prognostic value of p53 expression and proliferative activity, as indicated by the Ki-67, in endoscopic biopsy specimens. Specimens were immunologically stained with p53 and MIB-1 (Ki-67), and the MIB-1/Ki-67 labeling index (LI) was calculated. Classification of adenomas was based on...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2003.01482.x

    authors: Kubota K,Kakuta Y,Kawamura S,Saito S,Seki H,Kuniyoshi T

    更新日期:2003-06-01 00:00:00

  • Epstein-Barr virus-associated post-transplant primary smooth muscle tumor of the liver: report of an autopsy case.

    abstract::Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1996.tb03660.x

    authors: Sadahira Y,Moriya T,Shirabe T,Matsuno T,Manabe T

    更新日期:1996-08-01 00:00:00

  • Colitis nucleomigrans: The third type of microscopic colitis (part 1).

    abstract::Microscopic colitis (MC), encompassing collagenous colitis and lymphocytic colitis, is featured by chronic diarrhea, normal-looking endoscopic findings and unique microscopic appearance. After reviewing biopsied nonspecific colitis, we propose the third type of MC: colitis nucleomigrans (CN). Histopathological criteri...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12996

    authors: Tachibana M,Hanaoka T,Watanabe S,Matsushita M,Isono T,Tsutsumi Y

    更新日期:2020-10-01 00:00:00

  • Clonality analysis performed using human androgen receptor assay in a rare case of undifferentiated thymic carcinoma coexisting with type AB thymoma.

    abstract::We report a very rare case of combined thymic carcinomas: undifferentiated thymic carcinoma coexisting with type AB thymoma. The precise mechanism underlying the coexistence of these tumors remains unknown. Therefore, we used clonality analysis to ascertain whether the two tumors were clonally related. A 63-year-old w...

    journal_title:Pathology international

    pub_type:

    doi:10.1111/pin.12426

    authors: Karino F,Yokose T,Matsukuma S,Miyagi Y,Murakami S,Ito H,Nakayama H,Yamada K

    更新日期:2016-07-01 00:00:00

  • Cystic renal cell carcinoma: arose as a simple cyst, recurred repeatedly as a multicystic mass and finally presented as a solid mass.

    abstract::An unusual case of cystic renal cell carcinoma in a 70-year-old Japanese male is reported. He had had a simple renal cyst removed 1 year ago. On presentation the right kidney was surrounded by multiple translucent cysts, which varied in size from 1 to 50 mm. The cyst walls were lined by single-layered cuboidal epithel...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1998.tb03960.x

    authors: Shishikura Y,Furusato M,Aizawa S

    更新日期:1998-08-01 00:00:00

  • Renal cell carcinoma arising in a long pre-existing angiomyolipoma.

    abstract::Angiomyolipoma (AML) is a mixed mesenchymal tumor belonging to the family of perivascular epithelioid cell tumors. Concurrent development of AML and adult renal cell carcinoma (RCC) is very rare. Herein is presented a unique case in which RCC arose within a previously detected AML tumor mass. A 40-year-old woman had b...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2006.02075.x

    authors: Inomoto C,Umemura S,Sasaki Y,Yasuda M,Terachi T,Osamura RY

    更新日期:2007-03-01 00:00:00

  • Critical multi-organ emboli originating from collapsed, vulnerable caseous mitral annular calcification.

    abstract::Mitral annular calcification (MAC) is a generally asymptomatic abnormality found commonly in aged hearts. Some clinical studies have suggested that MAC should be considered an independent risk factor for stroke; however, whether the abnormality is indeed a risk factor remains controversial. We report a case in which d...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2012.02826.x

    authors: Matsuyama TA,Ishibashi-Ueda H,Ikeda Y,Nagatsuka K,Miyashita K,Amaki M,Kanzaki H,Kitakaze M

    更新日期:2012-07-01 00:00:00

  • Mixed tumor of the external auditory canal.

    abstract::A mixed tumor with apocrine differentiation seen in the external auditory canal of a 39 year old male is reported. The well demarcated polypoid tumor showed proliferation of elongated gland-like or duct-like structures lined by two rows of epithelial cells, occasionally accompanied by foci of keratinization. There wer...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1994.tb02589.x

    authors: Tang X,Tamura Y,Tsutsumi Y

    更新日期:1994-01-01 00:00:00

  • Novel function of histamine signaling via histamine receptors in cholesterol and bile acid metabolism: Histamine H2 receptor protects against nonalcoholic fatty liver disease.

    abstract::We have reported that the function of histamine and its receptors (HRs) has a close relationship with the development of nonalcoholic fatty liver disease (NAFLD). However, much less is known regarding its pathogenic and molecular mechanism(s), including the early stage of hepatic and intestinal function for lipid and ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12423

    authors: Yamada S,Guo X,Wang KY,Tanimoto A,Sasaguri Y

    更新日期:2016-07-01 00:00:00

  • Flow cytometric evaluation of nuclear DNA content in hepatoblastoma: further evidence for the inhomogeneity of the different subtypes.

    abstract::The DNA ploidy pattern of nine hepatoblastomas and three normal liver specimens was investigated by flow cytometry. Areas of unlike differentiation in the same tumor were investigated separately. Normal liver tissue and the fetal subtype were always diploid. Aneuploidy was found in the embryonal subtype. The one case ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1995.tb03492.x

    authors: Kröber S,Ruck P,Xiao JC,Kaiserling E

    更新日期:1995-07-01 00:00:00

  • Adenocarcinoma of small intestinal type in retroperitoneal mature teratoma.

    abstract::We report a case of small intestinal type adenocarcinoma arising in retroperitoneal mature cystic teratoma in a young male. The patient initially experienced intermittent abdominal pain, and radiographic workup revealed an encapsulated retroperitoneal mass. A laparotomy was performed and the resected specimen represen...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2010.02582.x

    authors: Terado Y,Kurata A,Ishida T,Imamura T,Sakamoto A

    更新日期:2010-10-01 00:00:00

  • Duct-acinar-islet cell tumor of the pancreas.

    abstract::A case of a rare pancreatic tumor, duct-acinar-islet cell tumor is presented. The tumor was incidentally found in the pancreatic body on computed tomography of a 21 year old male suffering from mumps. It was well demarcated from surrounding pancreas, and spherical in shape, measured 2.5 cm in diameter. Histologic and ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1995.tb03520.x

    authors: Okada Y,Mori H,Tsutsumi A

    更新日期:1995-09-01 00:00:00

  • Primary leiomyosarcoma of the vertebra: Case report and review of the literature.

    abstract::A case of primary leiomyosarcoma of a thoracic vertebra associated with a compression fracture in a 75-year-old woman was preoperatively thought to be granulation tissue. Surgical decompression was performed and the histological and immunohistochemical studies established the diagnosis of leiomyosarcoma. Based on the ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2004.01582.x

    authors: Sasaguri T,Tanimoto A,Kimura S,Kohno Y,Hirasawa M,Matsuki Y,Abe K,Hashimoto H,Hamada T,Sasaguri Y

    更新日期:2004-01-01 00:00:00

  • Renal carcinogenesis induced by ferric nitrilotriacetate in mice, and protection from it by Brazilian propolis and artepillin C.

    abstract::The protective effect of Brazilian propolis and its extract Artepillin C against ferric nitrilotriacetate (Fe-NTA)-induced renal lipid peroxidation and carcinogenesis was studied in male ddY mice. Fe-NTA-induced renal lipid peroxidation leads to a high incidence of renal cell carcinoma (RCC) in mice. Administration of...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2000.01097.x

    authors: Kimoto T,Koya S,Hino K,Yamamoto Y,Nomura Y,Micallef MJ,Hanaya T,Arai S,Ikeda M,Kurimoto M

    更新日期:2000-09-01 00:00:00

  • Microwave cell death: molecular analysis using DNA electrophoresis, PCR amplification and TUNEL.

    abstract::Microwave cell death (MCD) is unique in that microscopic morphology and antigenicity are well preserved, while enzymatic activity is lost. The aim of the present study was to carry out DNA electrophoresis, polymerase chain reaction (PCR) amplification and terminal deoxynucleotidyl transferase-mediated dUTP nick end-la...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2009.02368.x

    authors: Mori I,Ozaki T,Tabuse K,Utsunomiya H,Taniguchi E,Kakudo K

    更新日期:2009-05-01 00:00:00

  • The prognostic significance of N-myc downregulated gene 1 in lung adenocarcinoma.

    abstract::It has been reported that N-myc downstream regulated gene 1 (NDRG1) is related to the prognosis of non-small cell lung cancer (NSCLC), and associated with c-Myc degradation in NSCLC cell lines. However, the relationship of NDRG1 to prognosis or c-Myc expression in lung adenocarcinoma has not been well clarified. The p...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12644

    authors: Dai T,Dai Y,Murata Y,Husni RE,Nakano N,Sakashita S,Noguchi M

    更新日期:2018-04-01 00:00:00

  • Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change.

    abstract::A surgical case of inflammatory myofibroblastic tumor arising in the uterine corpus and exhibiting prominent myxoid change of the stroma is reported. The patient was a 63-year-old woman with a large tumor mass that filled the uterine cavity and measured 11 cm in maximal dimension. The tumor had a gelatinous appearance...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2006.02018.x

    authors: Shintaku M,Fukushima A

    更新日期:2006-10-01 00:00:00

  • Non-specific interstitial pneumonia as a manifestation of graft-versus-host disease following pediatric allogeneic hematopoietic stem cell transplantation.

    abstract::Bronchiolitis obliterans (BO) is generally believed to be a marker of pulmonary manifestation of graft-versus-host disease (GVHD) in patients who have undergone bone marrow transplantation for hematological malignancy. Pulmonary manifestations reported as GVHD (other than BO) include lymphocytic bronchiolitis with cel...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2009.02492.x

    authors: Miyagawa-Hayashino A,Sonobe M,Kubo T,Yoshizawa A,Date H,Manabe T

    更新日期:2010-02-01 00:00:00

  • The relationship between the gene mutation of p53 and the protein expression of p53 and Ki-67 in non-Hodgkin's lymphomas.

    abstract::The relationship between the mutation of the p53 gene and the expression of the p53 protein and the Ki-67 antigen has been investigated in 115 cases with non-Hodgkin's lymphoma, using the immunohistochemical double staining technique, single-strand conformational polymorphism and DNA sequencing methods. Eighteen cases...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1996.tb03588.x

    authors: Kuze T,Nakamura N,Hashimoto Y,Hojo H,Abe M,Wakasa H

    更新日期:1996-02-01 00:00:00

  • Epidermal growth factor receptor mutations in lung cancers.

    abstract::In 2004, two groups reported somatic mutations in the gene for the epidermal growth factor receptor (EGFR) in patients with non-small cell lung cancer (NSCLC), which were highly correlated with the clinical response to the anticancer drug, gefitinib. Since then, a tremendous amount of knowledge has accumulated, and sh...

    journal_title:Pathology international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1827.2007.02098.x

    authors: Yatabe Y,Mitsudomi T

    更新日期:2007-05-01 00:00:00