Flow cytometric evaluation of nuclear DNA content in hepatoblastoma: further evidence for the inhomogeneity of the different subtypes.

abstract：:YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...

journal_title：Pathology international

authors： Fukuda T,Kamishima T,Kakihara T,Yamada T,Matsumoto K,Uchiyama M,Suzuki T

更新日期：1997-08-01 00:00:00

abstract：:Nestin is an intermediate filament that was first identified in neural progenitor cells. It is expressed in various cell types in the nervous system as well as in other systems. In the present study, we investigated nestin expression in non-neoplastic salivary gland tissue and in salivary gland tumors. In non-neoplast...

journal_title：Pathology international

authors： Yanai H,Sato Y,Nagatsuka H,Yoshino T

更新日期：2013-10-01 00:00:00

abstract：:A quantitative model was devised for the purpose of evaluating interobserver agreement in the judgment of the nuclear atypia score of cancer cells in protocol studies. In this model, the mean nuclear atypia score (mu) among observers was considered to approximate the 'true' nuclear atypia score of the tumor, and with ...

journal_title：Pathology international

authors： Tsuda H,Akiyama F,Kurosumi M,Sakamoto G,Watanabe T

更新日期：2000-02-01 00:00:00

abstract：:A case of ovarian fibrosarcoma producing multiple cytokines is presented. The tumor occurred in the left ovary of a Japanese woman with epigastralgia, remittent fever, leukocytosis and slight thrombocytosis with moderate increase of mast cells in bone marrow, but lack of hormonal abnormality. The resected tumor of the...

journal_title：Pathology international

authors： Fukuda T,Yamaguchi T,Yamaki T,Suzuki T

更新日期：2001-09-01 00:00:00

abstract：:An extremely rare case of unilateral gonadoblastoma with mixed germ cell tumor arising in the ovary of a 27-year-old woman with 46,XX karyotype and two successful pregnancies is reported. The mixed germ cell tumor was composed of choriocarcinoma, embryonal carcinoma, yolk sac tumor, immature teratoma and dysgerminoma....

journal_title：Pathology international

authors： Zhao S,Kato N,Endoh Y,Jin Z,Ajioka Y,Motoyama T

更新日期：2000-04-01 00:00:00

abstract：:Calcifying fibrous tumor (CFT) is an uncommon lesion of uncertain cause and pathogenesis that has a unique histological appearance. These lesions are described mainly in the subcutaneous or deep soft tissues, followed by subserosal locations. Intrinsic visceral CFT is extremely rare. Herein is described a rare case of...

journal_title：Pathology international

authors： Elpek GO,Küpesiz GY,Ogüs M

更新日期：2006-04-01 00:00:00

abstract：:This report presents a case of neural fibrolipoma arising from the superficial peroneal nerve in the ankle. A 28-year-old woman was referred with a soft tissue mass in the anterior aspect of the right ankle, which had been gradually enlarging for the past 10 years. Magnetic resonance imaging showed a mass lesion, meas...

journal_title：Pathology international

authors： Akisue T,Matsumoto K,Yamamoto T,Kizaki T,Fujita I,Yoshiya S,Kurosaka M

更新日期：2002-11-01 00:00:00

abstract：:Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec...

journal_title：Pathology international

authors： Sadahira Y,Moriya T,Shirabe T,Matsuno T,Manabe T

更新日期：1996-08-01 00:00:00

abstract：:Accurate diagnosis of lymphoma includes the assessment of lineage-specific markers. Hematopoietic and lymphoid tissues express PAX5 exclusively in pro-B-cell to mature B-cell stages. However, some mature PAX5+ T-cell lymphomas have been reported. We report three cases of primary cutaneous CD30+ T-cell lymphoproliferat...

journal_title：Pathology international

authors： Hagiwara M,Tomita A,Takata K,Shimoyama Y,Yoshino T,Tomita Y,Nakamura S

更新日期：2012-04-01 00:00:00

abstract：:The occurrence of malignant neoplasms increases with advancing age. Although aging and carcinogenesis are basically different processes, there are phenomena common to each such as accumulation of DNA damage and abnormal proteins. Gastric and colorectal carcinomas are representative tumors in which the prevalence and t...

journal_title：Pathology international

authors： Arai T,Takubo K

更新日期：2007-06-01 00:00:00

abstract：:The classical nomenclature and categorization of neoplastic and non-neoplastic nodular lesions of the liver are being revised due to the tremendous volume of information recently published on this issue. The diagnostic histopathology of non-neoplastic nodular (tumor-like) lesions of the liver that are recognizable in ...

journal_title：Pathology international

authors： Nakanuma Y

更新日期：1995-10-01 00:00:00

abstract：:An 80-year-old woman with a pleomorphic carcinoma (PC) producing hCG was admitted to Nippon Steel Hirohata Hospital because of an abnormal shadow on CT seen during a follow-up examination after surgery for breast cancer. A right upper lobectomy was performed due to rapid growth of the shadow 3 months later. Macroscopi...

journal_title：Pathology international

authors： Hirano H,Yoshida T,Sakamoto T,Yoshimura H,Fukuoka M,Tachibana S,Saito H,Ohkubo E,Nakasho K,Nishigami T

更新日期：2007-10-01 00:00:00

abstract：:A small proportion of patients with chronic lymphocytic leukemia (CLL) may progress to large cell lymphoma, or Richter syndrome (RS). The large cells of RS may arise through transformation of the original CLL clone (clonally related) or represent a new neoplasm (clonally unrelated), which might be Epstein-Barr virus (...

journal_title：Pathology international

authors： Chen YA,Wang RC,Yang Y,Chuang SS

更新日期：2016-07-01 00:00:00

abstract：:We report on a rare distinctive variant of infiltrating ductal carcinoma characterized by sebaceous differentiation of tumor cells. The neoplasm was identified in a lumpectomy specimen from a 45-year-old woman with extensive metastatic disease. In addition to conventional in situ and invasive ductal components, approx...

journal_title：Pathology international

authors： Varga Z,Kolb SA,Flury R,Burkhard R,Caduff R

更新日期：2000-01-01 00:00:00

abstract：:Nodular fasciitis (NF) is a self-limiting benign disease that is characterized by rapid proliferation of fibroblastic and myofibroblastic cells. The characteristic gene fusion containing the USP6 gene is a genetic hallmark of NF and MYH9-USP6 is the most frequent fusion, suggesting that NF is not a reactive condition ...

journal_title：Pathology international

authors： Teramura Y,Yamazaki Y,Tanaka M,Sugiura Y,Takazawa Y,Takeuchi K,Nakayama T,Kaneko T,Musha Y,Funauchi Y,Ae K,Matsumoto S,Nakamura T

更新日期：2019-12-01 00:00:00

abstract：:Multiple myeloma (MM) is a plasma-cell neoplasm that can cause renal disorders. Renal lesions in MM can present with a very rare pathological manifestation involving a specific monoclonal immunoglobulin (Ig). We report the case of a 33-year-old woman who had edema, fatigue, elevated serum creatinine levels, hypoalbumi...

journal_title：Pathology international

authors： Watanabe H,Osawa Y,Goto S,Habuka M,Imai N,Ito Y,Hirose T,Chou T,Ohashi R,Shimizu A,Ehara T,Shimotori T,Narita I

更新日期：2015-01-01 00:00:00

abstract：:Cerebellar hypoplasia (CH) is one of the congenital abnormalities of the central nervous system and is seen in several diseases and syndromes. This study was conducted in order to examine methods for evaluating CH in fetus and neonate because CH has been diagnosed without any morphometric criteria at autopsy. We sampl...

journal_title：Pathology international

authors： Murakami A,Tanaka M,Ijiri R,Kato K,Yamashita S,Kurosawa K,Arai N,Aoki I,Tanaka Y

更新日期：2016-01-01 00:00:00

abstract：:Infarction of a breast fibroadenoma usually occurs in young females during pregnancy or lactation. This report describes a rare case of the total infarction of a fibroadenoma in a 58 year old postmenopausal woman. The chief complaint was a rapidly enlarged, slightly painful lump. Medullary carcinoma was suspected on p...

journal_title：Pathology international

authors： Ichihara S,Matsuyama T,Kubo K,Tamura Z,Aoyama H

更新日期：1994-05-01 00:00:00

abstract：:Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare kidney neoplasm that almost exclusively occurs in perimenopausal women, and long-term estrogen replacement is relevant to its pathogenesis. Herein is described an atypical case of MESTK uncovered in a 12-year-old premenarcheal girl without a history of...

journal_title：Pathology international

authors： Hara N,Kawaguchi M,Murayama S,Maruyama R,Tanikawa T,Takahashi K

更新日期：2005-10-01 00:00:00

abstract：:A 28-year-old woman complained of irregular menstruation. Abdominal ultrasound and magnetic resonance imaging (MRI) examinations revealed a cystic tumor in the left ovary. A histological examination of the resected ovary revealed that the lesion was a mature cystic teratoma. In this tumor, components such as skin with...

journal_title：Pathology international

authors： Kuroda N,Hirano K,Inui Y,Yamasaki Y,Toi M,Nakayama H,Hiroi M,Enzan H

更新日期：2001-11-01 00:00:00

abstract：:An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells thr...

journal_title：Pathology international

authors： Motosugi U,Ichikawa T,Yamaguchi H,Nakazawa T,Katoh R,Itakura J,Fujii H,Sato T,Araki T,Shimizu M

更新日期：2009-10-01 00:00:00

abstract：:This report describes a case of an immunocompetent 77-year-old male with Epstein-Barr virus (EBV)-positive lymphoproliferative disorder associated with calcified chronic subdural hematoma (CSH). On the day prior to consultation in our outpatient clinic, the patient fell from his bed, striking his frontal head on the f...

journal_title：Pathology international

authors： Sugita Y,Ohta M,Ohshima K,Niino D,Nakamura Y,Okada Y,Nakashima S

更新日期：2012-06-01 00:00:00

abstract：:The copper and iron status in the liver of non-tumor bearing Long-Evans Cinnamon (LEC) rats (average age 17 months) was investigated. A direct quantitation of loosely-bound copper and iron was also investigated by using a chelating agent, nitrilotriacetic acid (NTA-chelatable free copper and iron). Besides the total c...

journal_title：Pathology international

authors： Ma Y,Zhang D,Kawabata T,Kiriu T,Toyokuni S,Uchida K,Okada S

更新日期：1997-04-01 00:00:00

abstract：:Angioimmunoblastic T cell lymphoma (AITL) is characterized by the presence of atypical lymphocytes with clear cytoplasm and follicular dendritic cells, arborization of high endothelial blood vessels, and infiltration by inflammatory cells, such as epithelioid histiocytes, eosinophils, immunoblasts, and plasma cells. T...

journal_title：Pathology international

authors： Murakami Y,Shimada K,Kosugi H,Mori N

更新日期：2011-05-01 00:00:00

abstract：:Sarcomatoid carcinoma of the pancreas is an uncommon neoplasm. The immunohistochemical characteristics of this unique type of pancreatic tumor were studied. Histologically, there was diffuse proliferation of atypical spindle cells that had hyperchromatic, short, spindle-shaped nuclei and pale cytoplasm. A few tiny foc...

journal_title：Pathology international

authors： Higashi M,Takao S,Sato E

更新日期：1999-05-01 00:00:00

abstract：:The purpose of the present study was to clarify the difference of expression of two stem cell markers, nestin and c-kit, among various pancreatic epithelial tumors and evaluate their utility. Immunohistochemistry was done for 99 surgically resected pancreatic tumor specimens, including 20 ductal adenocarcinoma (DAC), ...

journal_title：Pathology international

authors： Ohike N,Sato M,Hisayuki T,Imataka H,Sato S,Wada Y,Saito K,Takahashi M,Tajiri T,Kunimura T,Morohoshi T

更新日期：2007-09-01 00:00:00

abstract：:An electron microscopic study of peripheral leukocytes obtained from a 39 year old woman with Hermansky-Pudlak syndrome was performed. Ceroid pigment granules were found within the lysosomes in 3.5% of monocytes and 5.4% of lymphocytes. Infrequently, pigment granules were also found in the parallel tubular arrays of l...

journal_title：Pathology international

authors： Sakuma T,Monma N,Satodate R,Satoh T,Takeda R,Kuriya S

更新日期：1995-11-01 00:00:00

abstract：:Stenosing flexor tenosynovitis, trigger finger, is a common clinical disorder causing painful locking or contracture of the involved digits, and most instances are idiopathic. This problem is generally caused by a size mismatch between the swollen flexor tendon and the thickened first annular pulley. Although hypertro...

journal_title：Pathology international

authors： Uchihashi K,Tsuruta T,Mine H,Aoki S,Nishijima-Matsunobu A,Yamamoto M,Kuraoka A,Toda S

更新日期：2014-06-01 00:00:00

abstract：:Homozygous deletion of 9p21, the locus harboring the p16 gene, has been reported as one of the most common genetic alterations in malignant mesotheliomas (MMs). Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens. ...

journal_title：Pathology international

authors： Takeda M,Kasai T,Enomoto Y,Takano M,Morita K,Kadota E,Nonomura A

更新日期：2010-05-01 00:00:00

abstract：:Niemann-Pick disease type C (NPC) is a neurovisceral lipid-storage disease. Although NPC patients show lipid storage in anterior horn cells of the spinal cord, little information is available regarding the electron microscopic analyses of the morphologies of intra-endosomal lipid like-materials in the anterior horn ce...

journal_title：Pathology international

authors： Kusunoki-Ii M,Kohama H,Kato K,Nomura Y,Nagashima K,Ninomiya H,Kato M,Kato S

更新日期：2020-07-01 00:00:00