Primary cutaneous CD30 positive T-cell lymphoproliferative disorders with aberrant expression of PAX5: report of three cases.

abstract：:The factors conferring the increased malignancy on lung adenocarcinoma with micropapillary component (AC-MPC) remain to be elucidated. On proteomics based on 2-dimensional gel electrophoresis, 19 proteins differentially expressed by more than 1.5-fold between AC-MPC and conventional adenocarcinoma (CAC); in particular...

journal_title：Pathology international

authors： Nakashima H,Jiang SX,Sato Y,Hoshi K,Matsumoto T,Nagashio R,Kobayashi M,Matsuo Y,Shiomi K,Hayakawa K,Saegusa M,Satoh Y

更新日期：2015-04-01 00:00:00

abstract：:The juxtaglomerular cell tumor (JGCT) of the kidney is a rare neoplasm which commonly secretes renin. This tumor often occurs in teenagers. This paper documents the 14th adult-onset (over 30-years-old) case with a giant JGCT which measured 9.0 x 8.0 x 7.5 cm. Histologically, this tumor was composed of both vascular an...

journal_title：Pathology international

authors： Kuroda N,Moriki T,Komatsu F,Miyazaki E,Hayashi Y,Naruse K,Nakayama H,Kiyoku H,Hiroi M,Shuin T,Enzan H

更新日期：2000-03-01 00:00:00

abstract：:Pulmonary papillary adenoma is a rare tumor. We analyzed a tumor which appeared in a 16-year-old Japanese woman. The tumor histologically showed papillary proliferation of one-layered tumor cells coating inflammatory fibrovascular cores. At the periphery of the tumor, the tumor cells grew in a lepidic fashion. The tum...

journal_title：Pathology international

authors： Masunaga A,Nagashio R,Iwamoto S,Takeyama N,Sato Y,Miyazaki A,Mitsuya T

更新日期：2012-09-01 00:00:00

abstract：:An extremely rare case of malignant mesothelioma of the pericardium is reported. The tumor appeared to be the biphasic type of diffuse malignant mesothelioma which present many small to fine lipid droplets in the cytoplasm, particularly that of the epithelial cell, and a positive immunohistochemical reaction with anti...

journal_title：Pathology international

authors： Ohmori T,Arita N,Okada K,Kondo M,Tabei R

更新日期：1995-08-01 00:00:00

abstract：:Rheumatoid nodule is a frequent and characteristic extra-articular manifestation of rheumatoid arthritis (RA). Its involvement of central nervous system is a rare occurrence with only a few reported cases. A 78-year-old man with severe arthritis showing the formation of rheumatoid nodule-like granulomas in the dura an...

journal_title：Pathology international

authors： Kamio N,Kuramochi S,Wang RJ,Hirose S,Hosoda Y

更新日期：1996-07-01 00:00:00

abstract：:Epstein-Barr virus (EBV) infection is associated with pathogenesis of various cancers, including extranodal natural killer/T-cell lymphoma, nasal type (ENKL). ENKL tumor cells are positive for EBV-encoded RNA1 (EBER1), which is the most useful marker to identify ENKL tumor cells in histopathology. Currently, EBER1 in ...

journal_title：Pathology international

authors： Ito Y,Makita S,Maeshima AM,Hatta S,Yuda S,Suzuki T,Fukuhara S,Munakata W,Taniguchi H,Suzuki T,Maruyama D,Izutsu K

更新日期：2019-07-01 00:00:00

abstract：:A case of a 66-year-old Japanese woman with two synchronous urinary bladder tumors, namely verrucous carcinoma and poorly differentiated squamous cell carcinoma, is described. Both tumors were accompanied by widespread squamous metaplasia in the background and unassociated with bilharzial infection. The poorly differe...

journal_title：Pathology international

authors： Oida Y,Yasuda M,Kajiwara H,Onda H,Kawamura N,Osamura RY

更新日期：1997-09-01 00:00:00

abstract：:Pleomorphic lobular carcinoma (PLC) of the breast is a variant of lobular carcinoma, characterized by loss of E-cadherin expression and high-grade morphologies. Whether the pathogenesis of PLC is in the ductal or the lobular lineage has been discussed. In this report, a case of PLC combined with apocrine carcinoma is ...

journal_title：Pathology international

authors： Ishii A,Oishi T,Kakuda Y,Yasui H,Kawata T,Muramatsu K,Takahashi K,Sugino T

更新日期：2019-05-01 00:00:00

abstract：:A 56-year-old male treated for a gastric yolk sac tumor with an adenocarcinomatous component is described. A mixed area of reticular and glandular neoplastic components was morphologically identified in this tumor. Immunohistochemically, the yolk sac tumor expressed alpha-fetoprotein (AFP), placental alkaline phosphat...

journal_title：Pathology international

authors： Suzuki T,Kimura N,Shizawa S,Yabuki N,Yamaki T,Sasano H,Nagura H

更新日期：1999-06-01 00:00:00

abstract：:Tec is a novel non-receptor-type protein tyrosine kinase that was originally identified from a murine liver cDNA library. While the function of Tec remains unknown, it was shown recently that two Tec-related kinases are involved directly in the growth and differentiation of bone marrow stem cells. As the localization ...

journal_title：Pathology international

authors： Kazama A,Mano H,Morishita Y,Mori S

更新日期：1996-05-01 00:00:00

abstract：:The origin of histiocyte-like cells in malignant fibrous histiocytoma (MFH) remains controversial. To determine whether histiocyte-like cells and multinucleated giant cells show reactive or neoplastic proliferation, we transplanted human storiform-pleomorphic MFH to nude mice and investigated the origin of histiocyte-...

journal_title：Pathology international

authors： Hatano H,Tokunaga K,Ogose A,Imaizumi S,Hayami T,Yamagiwa H,Hotta T,Endo N,Takahashi HE,Naito M

更新日期：1999-01-01 00:00:00

abstract：:Angiomyxomas are a group of relatively rare mesenchymal myxoid tumors. Three types of angiomyxomas have been identified: superficial angiomyxoma, aggressive angiomyxoma and angiomyofibroblastoma. These tumors have a predilection for occurring in the perineum of middle-aged females and are often clinically diagnosed as...

journal_title：Pathology international

authors： Ustun C,Malazgirt Z,Kandemir B,Kocak I,Bolat I,Gumus S

更新日期：1998-12-01 00:00:00

abstract：:Cellular senescence is defined as irreversible cell arrest and could work as a safeguard against tumorigenesis. This mechanism was examined in chronic viral hepatitis-related hepatocarcinogenesis. By using surgical resected or wedge biopsied liver specimens from 87 chronic viral hepatitis patients in whom 35 neoplasti...

journal_title：Pathology international

authors： Ikeda H,Sasaki M,Sato Y,Harada K,Zen Y,Mitsui T,Nakanuma Y

更新日期：2009-07-01 00:00:00

abstract：:The KIT, epidermal growth factor receptor (EGFR) and HER-2 oncoproteins have tyrosine kinase activity and are molecular targets in human cancer therapy. To clarify the significance of KIT, EGFR, and HER-2 in undifferentiated thyroid carcinoma (UTC), the expression of these receptors and tyrosine phosphorylation was ex...

journal_title：Pathology international

authors： Murakawa T,Tsuda H,Tanimoto T,Tanabe T,Kitahara S,Matsubara O

更新日期：2005-12-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVGC) is defined as a neoplasm comprising monoclonal proliferation of EBV-infected gastric epithelial cells. Although the typical histology is gastric carcinoma with lymphoid stroma (GCLS), the histologic features of the tumor vary. We report herein the case of a...

journal_title：Pathology international

authors： Shimizu A,Takahashi T,Kushima R,Sentani K,Yasui W,Matsuno Y

更新日期：2018-01-01 00:00:00

abstract：:A bilateral ovarian tumor composed of mixed Brenner tumor and struma ovarii in the right ovary and mature cystic teratoma in the left ovary, is described. Mixed Brenner tumor and struma ovarii is rare; eight cases are reviewed. In this case, in addition to the typical Brenner tumor and struma ovarii, some nests compos...

journal_title：Pathology international

authors： Yoshida M,Obayashi C,Tachibana M,Minami R

更新日期：2004-10-01 00:00:00

abstract：:Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare, recently recognized neoplasm occurring predominantly in the subcutaneous tissue of the lower limbs of adults. We report a case of PHAT in an 83-year-old woman who presented with a 5.0 x 5.0 x 2.0 cm mass in the soft part of her left thigh. Histologically, the...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T

更新日期：2002-10-01 00:00:00

abstract：:A subcutaneous myopericytoma-type perivascular myoma arising in the elbow of a 61-year-old woman is described. The tumor was well demarcated and consisted microscopically of small ovoid and spindle cells arranged in a concentric fashion, surrounding small to medium-sized vessels and imparting a superficial resemblance...

journal_title：Pathology international

authors： Mikami Y,Shiomi T,Manabe T

更新日期：2002-01-01 00:00:00

abstract：:Ameloblastoma is an odontogenic tumor of the jaw. It most frequently occurs in the mandible, and less often in the maxilla. Mandibular ameloblastoma harbors a BRAF mutation that causes a valine (V) to glutamic acid (E) substitution at codon 600 (BRAFV600E ). We examined specimens from 32 Japanese patients to detect th...

journal_title：Pathology international

authors： Seki-Soda M,Sano T,Ito K,Yokoo S,Oyama T

更新日期：2020-04-01 00:00:00

abstract：:Teratoid Wilms' tumor is an unusual morphological entity characterized by a classic triphasic malignancy with predominantly heterologous tissue. The authors describe two cases of teratoid Wilms' tumor with an extrarenal site: one in a 13-year-old girl with vaginal spotting (patient 1) and another in a 1-day-old girl w...

journal_title：Pathology international

authors： Song JS,Kim IK,Kim YM,Khang SK,Kim KR,Lee Y

更新日期：2010-01-01 00:00:00

abstract：:Bronchiolitis obliterans (BO) is generally believed to be a marker of pulmonary manifestation of graft-versus-host disease (GVHD) in patients who have undergone bone marrow transplantation for hematological malignancy. Pulmonary manifestations reported as GVHD (other than BO) include lymphocytic bronchiolitis with cel...

journal_title：Pathology international

authors： Miyagawa-Hayashino A,Sonobe M,Kubo T,Yoshizawa A,Date H,Manabe T

更新日期：2010-02-01 00:00:00

abstract：:The alpha subunit of a GTP-binding protein, Go, was investigated in pulmonary neuroendocrine neoplasms and fetal tissues of the lung by an immunohistochemical method. Positive immunostaining for the alpha subunit of Go (Go alpha) was found predominantly on the cell membrane and found occasionally in the cytoplasm. Typ...

journal_title：Pathology international

authors： Kawano N,Ito T,Kitamura H,Shibagaki T,Kameda Y,Nakamura N,Kanisawa M

更新日期：1996-06-01 00:00:00

abstract：:BAT-26 instability, a sensitive marker for the high-frequency microsatellite instability (MSI-H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI-H gastric cancer samples showed BAT-26 instability, as assessed using 12 dinucleotide microsatellite mar...

journal_title：Pathology international

authors： Jin Z,Tamura G,Satoh M,Meguro T,Miura T,Hayashi M,Osakabe M,Ohmura K,Ogata S,Endoh Y,Motoyama T

更新日期：2001-06-01 00:00:00

abstract：:We report a case of cutaneous squamous cell carcinoma (CSCC), initially coexisting with invasive extramammary Paget's disease (EMPD), in the scrotum of an 84-year-old man. The patient initially had a rash and pruritus before presenting with a pedunculated scrotal mass surrounded by widespread erythema. He underwent to...

journal_title：Pathology international

authors： Kitano A,Izumi M,Tamura K,Tonegawa M,Etou T,Kishida Y

更新日期：2019-10-01 00:00:00

abstract：:An intrathoracic mass was discovered on magnetic resonance imaging (MRI) of the spine in a 37-year-old Caucasian man with a 1 year history of progressively severe upper back pain. A subsequent chest CT scan indicated a 4 cm left hilar mass, extending to the apex and encasing a portion of the left bronchus and pulmonar...

journal_title：Pathology international

authors： Bahrami A,Allen TC,Cagle PT

更新日期：2008-11-01 00:00:00

abstract：:We present a case of uterine intravenous leiomyomatosis associated with multiple pulmonary metastases with bullae-like cystic change. A 53-year-old woman who had undergone hysterectomy 5 years previously underwent an operation for multiple pulmonary nodules with bullae formation. After resection of several large bulla...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T,Hisayoshi T,Asano G

更新日期：2001-05-01 00:00:00

abstract：:Several short forms of alternatively spliced Murine double minute 2 (MDM2) transcripts have recently been shown to correlate with high-grade malignancy in a number of human tumors. We examined the frequency of splice variants and their correlation with clinicopathological features in 60 cases of human breast cancer. S...

journal_title：Pathology international

authors： Hori M,Shimazaki J,Inagawa S,Itabashi M,Hori M

更新日期：2000-10-01 00:00:00

abstract：:Resistance to retroviral infection is often regulated by multiple genes that control different aspects of the host-virus interaction. Genetically distinct inbred strains of mice differ in their susceptibility to retrovirus and have allowed the identification of several host-resistant loci that regulate the host defens...

journal_title：Pathology international

authors： Kitagawa M,Aizawa S,Ikeda H,Hirokawa K

更新日期：1996-10-01 00:00:00

abstract：:The etiological role of human papillomavirus (HPV) in esophageal carcinoma (EC) in relation to p53, mdm2, p21(waf), c-erbB2 and the overall survival (OS) rate was investigated. Tumor and normal tissues from 50 EC were evaluated by polymerase chain reaction and InnoLiPA for HPV. Single strand conformation polymorphism/...

journal_title：Pathology international

authors： Bahnassy AA,Zekri AR,Abdallah S,El-Shehaby AM,Sherif GM

更新日期：2005-02-01 00:00:00

abstract：:Desminopathy is a familial or sporadic skeletal and cardiac muscular dystrophy caused by mutation in the desmin gene. Desmin-reactive deposits in the affected muscles are the morphological hallmarks of this disease. Herein is reported an autopsy case of a 57-year-old Japanese man with adult-onset skeletal muscle weakn...

journal_title：Pathology international

authors： Yuri T,Miki K,Tsukamoto R,Shinde A,Kusaka H,Tsubura A

更新日期：2007-01-01 00:00:00