Perivascular myoma: case report with immunohistochemical and ultrastructural studies.

abstract：:According to the World Health Organization classification, neoplasms with perivascular epithelioid cell differentiation (PEComas) are mesenchymal tumors composed of histologically and immunohistochemically distinctive PEC. Generally, nearly all PEComas have immunoreactivity for both melanocytic (HMB-45 and/or melan A)...

journal_title：Pathology international

authors： Adachi Y,Horie Y,Kitamura Y,Nakamura H,Taniguchi Y,Miwa K,Fujioka S,Nishimura M,Hayashi K

更新日期：2008-03-01 00:00:00

abstract：:We report a case of small intestinal type adenocarcinoma arising in retroperitoneal mature cystic teratoma in a young male. The patient initially experienced intermittent abdominal pain, and radiographic workup revealed an encapsulated retroperitoneal mass. A laparotomy was performed and the resected specimen represen...

journal_title：Pathology international

authors： Terado Y,Kurata A,Ishida T,Imamura T,Sakamoto A

更新日期：2010-10-01 00:00:00

abstract：:An electron microscopic study of peripheral leukocytes obtained from a 39 year old woman with Hermansky-Pudlak syndrome was performed. Ceroid pigment granules were found within the lysosomes in 3.5% of monocytes and 5.4% of lymphocytes. Infrequently, pigment granules were also found in the parallel tubular arrays of l...

journal_title：Pathology international

authors： Sakuma T,Monma N,Satodate R,Satoh T,Takeda R,Kuriya S

更新日期：1995-11-01 00:00:00

abstract：:To test whether a subset of esophageal squamous cell carcinomas (SCC) develop through a deficiency in DNA mismatch repair, we examined microsatellite instability (MSI) using 11 microsatellite markers including BAT-26, hMLH1 protein expression by immunohistochemistry, and methylation status of the hMLH1 promoter by met...

journal_title：Pathology international

authors： Hayashi M,Tamura G,Jin Z,Kato I,Sato M,Shibuya Y,Yang S,Motoyama T

更新日期：2003-05-01 00:00:00

abstract：:Multiple injections with a mouse monoclonal anti-rat Thy-1 antibody (five times, at weekly intervals) induced marked glomerular sclerotic lesions which are characterized by adhesion of glomerular capillaries to Bowman's capsule and persistent proteinuria in rats. Abnormal production of type I collagen and increased ac...

journal_title：Pathology international

authors： Yagi M,Yamamoto T,Kato S,Nagano N,Kihara I

更新日期：1998-07-01 00:00:00

abstract：:Two cases of endometrial low-grade stromal sarcoma with ovarian sex cord-like differentiation occurring in a 39-year-old woman and a 42-year-old woman are presented. Both tumors, which were intramyometrial and measured 7.5 cm and 7.0 cm in greatest diameter, respectively, showed a multinodular, ill-demarcated, and yel...

journal_title：Pathology international

authors： Fukunaga M,Miyazawa Y,Ushigome S

更新日期：1997-06-01 00:00:00

abstract：:The juxtaglomerular cell tumor (JGCT) of the kidney is a rare neoplasm which commonly secretes renin. This tumor often occurs in teenagers. This paper documents the 14th adult-onset (over 30-years-old) case with a giant JGCT which measured 9.0 x 8.0 x 7.5 cm. Histologically, this tumor was composed of both vascular an...

journal_title：Pathology international

authors： Kuroda N,Moriki T,Komatsu F,Miyazaki E,Hayashi Y,Naruse K,Nakayama H,Kiyoku H,Hiroi M,Shuin T,Enzan H

更新日期：2000-03-01 00:00:00

abstract：:The great majority of the cases clinically diagnosed as primary aldosteronism (PA) have been caused by aldosterone-producing adenoma (APA) or idiopathic hyperaldosteronism (IHA). The differential diagnosis of both subtypes of PA is important due to the different therapeutic modes but clinically it is sometimes difficu...

journal_title：Pathology international

authors： Nakamura Y,Felizola SJ,Satoh F,Konosu-Fukaya S,Sasano H

更新日期：2014-10-01 00:00:00

abstract：:A case of an inflammatory pseudotumor of the liver in a 75-year-old female with chronic hepatitis C whose radiologic features simulated that of hepatocellular carcinoma (HCC) is presented. On imaging studies, hypervascularity by CO2 ultrasound (US) angiography, enhancement at an early phase and isodensity at a late ph...

journal_title：Pathology international

authors： Kim SR,Hayashi Y,Kudo M,Matsuoka T,Imoto S,Sasaki K,Shintani S,Song KB,Park SY,Kim JH,Ando K,Koterazawa T,Kim KI,Ninomiya T

更新日期：1999-08-01 00:00:00

abstract：:Gastric lipomas are uncommon lesions, usually single and located in the antrum. Common symptoms include upper digestive bleeding, anemia, and intestinal obstruction. Alternatively, they may remain asymptomatic, and detectable only at autopsy. A case of a 72-year-old man, who died of myocardial infarction, was found at...

journal_title：Pathology international

authors： Ventura L,Leocata P,Guadagni S,Ventura T

更新日期：1997-08-01 00:00:00

abstract：:Angioimmunoblastic T cell lymphoma (AITL) is characterized by the presence of atypical lymphocytes with clear cytoplasm and follicular dendritic cells, arborization of high endothelial blood vessels, and infiltration by inflammatory cells, such as epithelioid histiocytes, eosinophils, immunoblasts, and plasma cells. T...

journal_title：Pathology international

authors： Murakami Y,Shimada K,Kosugi H,Mori N

更新日期：2011-05-01 00:00:00

abstract：:The chemokine receptor CXCR4 belongs to the large superfamily of G protein-coupled receptors and has been identified to play a crucial role in a number of biological processes, including the trafficking and homeostasis of immune cells such as T lymphocytes. CXCR4 has also been found to be a prognostic marker in variou...

journal_title：Pathology international

authors： Furusato B,Mohamed A,Uhlén M,Rhim JS

更新日期：2010-07-01 00:00:00

abstract：:YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...

journal_title：Pathology international

authors： Fukuda T,Kamishima T,Kakihara T,Yamada T,Matsumoto K,Uchiyama M,Suzuki T

更新日期：1997-08-01 00:00:00

abstract：:The purpose of the present paper was to examine the level of apoptosis and the relationships among apoptosis, apoptosis-associated proteins, and proliferating potential in lymphoma tissues to clarify the characteristics of apoptosis in diffuse large B-cell lymphomas (DLBCL) of the central nervous system (CNS). The for...

journal_title：Pathology international

authors： Arai M,Sasaki A,Saito N,Nakazato Y

更新日期：2005-03-01 00:00:00

abstract：:Malignant lymphoma arising in the stomach of a 23-year-old Japanese man with systemic sarcoidosis is presented. The patient was followed because of systemic sarcoidosis involving the lungs, eyes, and lymph nodes. Biopsy specimens from the stomach were repeated because of recurrent epigastralgia and multiple ulceration...

journal_title：Pathology international

authors： Fukuda T,Sato K,Tachikawa S,Ohnuki K,Ohtani H,Suzuki T

更新日期：1997-12-01 00:00:00

abstract：:Myofibroblasts have ultrastructural and functional characteristics intermediate between fibroblasts and smooth muscle cells. Previous studies indicated that most myofibroblasts express actin and vimentin but not desmin immunophenotypes. Two benign intramuscular myofibroblastic tumors which displayed a desmin-positive ...

journal_title：Pathology international

authors： Yang P,Hirose T,Seki K,Hasegawa T,Hizawa K,Sano T

更新日期：1996-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVGC) is defined as a neoplasm comprising monoclonal proliferation of EBV-infected gastric epithelial cells. Although the typical histology is gastric carcinoma with lymphoid stroma (GCLS), the histologic features of the tumor vary. We report herein the case of a...

journal_title：Pathology international

authors： Shimizu A,Takahashi T,Kushima R,Sentani K,Yasui W,Matsuno Y

更新日期：2018-01-01 00:00:00

abstract：:Adenomyoma of the small intestine is a rare tumor-like lesion composed of exocrine-type ducts and hypertrophic smooth muscle. We describe two cases of adenomyoma of the small intestine. One was an ileal adenomyoma that presented with intussusception occurring in a 7-month-old boy. The other was a jejunal adenomyoma fo...

journal_title：Pathology international

authors： Park HS,Lee SO,Lee JM,Kang MJ,Lee DG,Chung MJ

更新日期：2003-02-01 00:00:00

abstract：:Alopecia was induced in male and female neonatal C57BL mice by a single intraperitoneal injection of 60 mg/kg N-methyl-N-nitrosourea (MNU). MNU administration was most effective in the 8-day-old mice and less effective in the 5-day-old mice (at active and early anagen stages of the first hair cycle, respectively). No ...

journal_title：Pathology international

authors： Yoshizawa K,Nambu H,Yamamoto D,Yang J,Kiyozuka Y,Shikata N,Tsubura A

更新日期：2000-03-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare clinicopathological entity causing severe pulmonary hypertension. Its histological features include widespread tumor emboli along with fibrocellular intimal proliferation and thrombus formation in the small arteries and arterioles of the lungs. The result is ...

journal_title：Pathology international

authors： Chinen K,Kazumoto T,Ohkura Y,Matsubara O,Tsuchiya E

更新日期：2005-01-01 00:00:00

abstract：:Under the condition of obvious iron-overload, there is a zonal hemosiderin (iron) deposition in hepatic lobules. The deposition is heaviest in the periportal (zone 1) and lightest in the perivenous (zone 3) hepatocytes. However, the mechanism for this pattern of iron deposition is obscure. Hepatic tissues from control...

journal_title：Pathology international

authors： Lu JP,Hayashi K

更新日期：1995-03-01 00:00:00

abstract：:In papillary thyroid carcinoma (PTC) in cytological and surgical specimens, fine chromatin, nuclear grooves and nuclear pseudoinclusions are the hallmarks of diagnosis. We investigated the significance of these nuclear changes in neoplastic non-PTC lesions. Fine needle aspiration biopsies (FNAB) of thyroid lesions wer...

journal_title：Pathology international

authors： Mai KT,Yazdi HM,Commons AS,Perkins DG,MacDonald L

更新日期：1999-07-01 00:00:00

abstract：:Reported herein is a 57-year-old man infected by Sparganum mansoni, a kind of tapeworm, showing a solitary nodule of the middle lobe of the right lung. Because a transbronchial biopsy could not diagnose the nodule, a right middle lobectomy was performed on suspicion of malignant tumor. The lesion was diagnosed as spar...

journal_title：Pathology international

authors： Iwatani K,Kubota I,Hirotsu Y,Wakimoto J,Yoshioka M,Mori T,Ito T,Nomori H

更新日期：2006-11-01 00:00:00

abstract：:A cytometrical image analyzing method for nuclear protein was established using WinROOF, a commercially available, inexpensive software, to determine the status of both estrogen and progesterone receptors. Immunohistochemical evaluation of estrogen receptors (ER) and progesterone receptors (PR) was performed with the ...

journal_title：Pathology international

authors： Hatanaka Y,Hashizume K,Nitta K,Kato T,Itoh I,Tani Y

更新日期：2003-10-01 00:00:00

abstract：:The alpha subunit of a GTP-binding protein, Go, was investigated in pulmonary neuroendocrine neoplasms and fetal tissues of the lung by an immunohistochemical method. Positive immunostaining for the alpha subunit of Go (Go alpha) was found predominantly on the cell membrane and found occasionally in the cytoplasm. Typ...

journal_title：Pathology international

authors： Kawano N,Ito T,Kitamura H,Shibagaki T,Kameda Y,Nakamura N,Kanisawa M

更新日期：1996-06-01 00:00:00

abstract：:Nodular fasciitis (NF) is a self-limiting benign disease that is characterized by rapid proliferation of fibroblastic and myofibroblastic cells. The characteristic gene fusion containing the USP6 gene is a genetic hallmark of NF and MYH9-USP6 is the most frequent fusion, suggesting that NF is not a reactive condition ...

journal_title：Pathology international

authors： Teramura Y,Yamazaki Y,Tanaka M,Sugiura Y,Takazawa Y,Takeuchi K,Nakayama T,Kaneko T,Musha Y,Funauchi Y,Ae K,Matsumoto S,Nakamura T

更新日期：2019-12-01 00:00:00

abstract：:The factors conferring the increased malignancy on lung adenocarcinoma with micropapillary component (AC-MPC) remain to be elucidated. On proteomics based on 2-dimensional gel electrophoresis, 19 proteins differentially expressed by more than 1.5-fold between AC-MPC and conventional adenocarcinoma (CAC); in particular...

journal_title：Pathology international

authors： Nakashima H,Jiang SX,Sato Y,Hoshi K,Matsumoto T,Nagashio R,Kobayashi M,Matsuo Y,Shiomi K,Hayakawa K,Saegusa M,Satoh Y

更新日期：2015-04-01 00:00:00

abstract：:Presented herein are two unusual epithelioid angiomyolipomas (AML) displaying prominent stromal sclerosis. Both patients were middle-aged women without a clinical history of tuberous sclerosis. One patient (case 1) had a 2 cm lesion arising in the renal cortex, and another (case 2) had a pararenal retroperitoneal tumo...

journal_title：Pathology international

authors： Matsuyama A,Hisaoka M,Ichikawa K,Fujimori T,Udo K,Uchihashi K,Aoki S,Hashimoto H

更新日期：2008-05-01 00:00:00

abstract：:A quantitative model was devised for the purpose of evaluating interobserver agreement in the judgment of the nuclear atypia score of cancer cells in protocol studies. In this model, the mean nuclear atypia score (mu) among observers was considered to approximate the 'true' nuclear atypia score of the tumor, and with ...

journal_title：Pathology international

authors： Tsuda H,Akiyama F,Kurosumi M,Sakamoto G,Watanabe T

更新日期：2000-02-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are multi-functional cytokines, which belong to the transforming growth factor-β (TGF-β) family. In some cancer tissues, aberrant expression of various BMP signal components has been detected. Here, we describe the divergent roles of BMPs during the progression of cancer. BMPs exhibi...

journal_title：Pathology international

authors： Ehata S,Yokoyama Y,Takahashi K,Miyazono K

更新日期：2013-06-01 00:00:00