Microsatellite instability in esophageal squamous cell carcinoma is not associated with hMLH1 promoter hypermethylation.

abstract：:BAT-26 instability, a sensitive marker for the high-frequency microsatellite instability (MSI-H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI-H gastric cancer samples showed BAT-26 instability, as assessed using 12 dinucleotide microsatellite mar...

journal_title：Pathology international

authors： Jin Z,Tamura G,Satoh M,Meguro T,Miura T,Hayashi M,Osakabe M,Ohmura K,Ogata S,Endoh Y,Motoyama T

更新日期：2001-06-01 00:00:00

abstract：:Gonadotropin releasing hormone (GnRH) analogs can cause regression of hormone-dependent breast carcinomas via the specific GnRH receptor (GnRH-R). In an attempt to obtain a better understanding of GnRH actions in human breast carcinoma, the expression of GnRH-R was examined immunohistochemically in 58 invasive ductal ...

journal_title：Pathology international

authors： Moriya T,Suzuki T,Pilichowska M,Ariga N,Kimura N,Ouchi N,Nagura H,Sasano H

更新日期：2001-05-01 00:00:00

abstract：:To examine the relationship between the scavenger receptor A (SRA) index (the number of SRA+ cells observed in 10 high power fields of peripheral blood (PB) smear samples; normal upper limit <30) and coronary thrombus, 389 thrombi obtained from 393 patients with acute ST elevation myocardial infarction were examined. ...

journal_title：Pathology international

authors： Emura I,Usuda H,Fujita T,Ebe K,Nagai T

更新日期：2011-06-01 00:00:00

abstract：:A case of serous cystadenocarcinoma of the pancreas in an 85-year-old woman is reported. The tumor extensively involved the body and tail of the pancreas and contiguously invaded the spleen. The histopathology of the tumor was similar to that of serous cystadenoma, but mild nuclear hyperchromatism and atypism were not...

journal_title：Pathology international

authors： Shintaku M,Arimoto A,Sakita N

更新日期：2005-07-01 00:00:00

abstract：:A 70-year-old man with metastatic liver tumors showed carcinoid syndrome with clinical symptoms of facial flushing, palpitation, dyspnea, and an itching sensation. Regurgitation of the tricuspid and aortic valves was observed by echocardiography. An elevated serum level of serotonin and a high urine excretion of serot...

journal_title：Pathology international

authors： Sakai D,Murakami M,Kawazoe K,Tsutsumi Y

更新日期：2000-05-01 00:00:00

abstract：:Circulating leukocytes, particularly neutrophils and monocytes, are important effector cells in the induction of many forms of glomerulonephritis. Adhesion molecules, especially selectins, are also thought to be critical for the development of this disease. We examined the possible suppressive effect of soluble E-sele...

journal_title：Pathology international

authors： Takahashi S,Araki K,Araki M,Ito MR,Nakatani K,Fujii H,Izui S,Vassalli P,Nose M

更新日期：2002-03-01 00:00:00

abstract：:An electron microscopic study of peripheral leukocytes obtained from a 39 year old woman with Hermansky-Pudlak syndrome was performed. Ceroid pigment granules were found within the lysosomes in 3.5% of monocytes and 5.4% of lymphocytes. Infrequently, pigment granules were also found in the parallel tubular arrays of l...

journal_title：Pathology international

authors： Sakuma T,Monma N,Satodate R,Satoh T,Takeda R,Kuriya S

更新日期：1995-11-01 00:00:00

abstract：:Bronchiolitis obliterans (BO) is generally believed to be a marker of pulmonary manifestation of graft-versus-host disease (GVHD) in patients who have undergone bone marrow transplantation for hematological malignancy. Pulmonary manifestations reported as GVHD (other than BO) include lymphocytic bronchiolitis with cel...

journal_title：Pathology international

authors： Miyagawa-Hayashino A,Sonobe M,Kubo T,Yoshizawa A,Date H,Manabe T

更新日期：2010-02-01 00:00:00

abstract：:A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobect...

journal_title：Pathology international

authors： Zhang Z,Nonaka H,Nagayama T,Hatori T,Ihara F,Zhang L,Akima M,Shiba T

更新日期：2001-12-01 00:00:00

abstract：:Many new members of the S-100 genes are known to be associated with cell differentiation, malignant transformation, and cell cycle. Of the S-100 genes examined in the present study, calcyclin, calpactin I light chain and calvasculin were expressed in most human epithelial tumor cells, and their expression levels diffe...

journal_title：Pathology international

authors： Matsumoto T,Murao S,Kito K,Kihana T,Matsuura S,Ueda N

更新日期：1997-06-01 00:00:00

abstract：:Actinic cheilitis (AC) is an early keratocyte neoplasia with inflammation that occurs in the lip vermillion with the potential to develop into invasive squamous cell carcinoma (SCC). The expression of the intracellular enzyme indoleamine 2,3-dioxygenase (IDO) by antigen-presenting cells and/or tumor cells has been des...

journal_title：Pathology international

authors： von Bubnoff D,Zahn S,Wenzel J,Wilms H,Bieber T,Lüftl M

更新日期：2012-02-01 00:00:00

abstract：:An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells thr...

journal_title：Pathology international

authors： Motosugi U,Ichikawa T,Yamaguchi H,Nakazawa T,Katoh R,Itakura J,Fujii H,Sato T,Araki T,Shimizu M

更新日期：2009-10-01 00:00:00

abstract：:Rheumatoid nodule is a frequent and characteristic extra-articular manifestation of rheumatoid arthritis (RA). Its involvement of central nervous system is a rare occurrence with only a few reported cases. A 78-year-old man with severe arthritis showing the formation of rheumatoid nodule-like granulomas in the dura an...

journal_title：Pathology international

authors： Kamio N,Kuramochi S,Wang RJ,Hirose S,Hosoda Y

更新日期：1996-07-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare clinicopathological entity causing severe pulmonary hypertension. Its histological features include widespread tumor emboli along with fibrocellular intimal proliferation and thrombus formation in the small arteries and arterioles of the lungs. The result is ...

journal_title：Pathology international

authors： Chinen K,Kazumoto T,Ohkura Y,Matsubara O,Tsuchiya E

更新日期：2005-01-01 00:00:00

abstract：:We report a very rare case of combined thymic carcinomas: undifferentiated thymic carcinoma coexisting with type AB thymoma. The precise mechanism underlying the coexistence of these tumors remains unknown. Therefore, we used clonality analysis to ascertain whether the two tumors were clonally related. A 63-year-old w...

journal_title：Pathology international

authors： Karino F,Yokose T,Matsukuma S,Miyagi Y,Murakami S,Ito H,Nakayama H,Yamada K

更新日期：2016-07-01 00:00:00

abstract：:We report a case of intrarenal teratoma in a 6-year-old boy. Two years before his operation, multicystic masses had been found in the left side of his abdomen. In the operation, three main cystic masses were located in the upper and lower poles of the left kidney, which were removed in pieces. Histologically, the cyst...

journal_title：Pathology international

authors： Otani M,Tsujimoto S,Miura M,Nagashima Y

更新日期：2001-07-01 00:00:00

abstract：:Morphologic features and neoplastic potentials of bile duct adenoma (BDA) and von Meyenburg complex (VMC)-like duct arising in chronic liver disease were unknown. Thirty-five BDAs and 12 VMC-like duct lesions were observed in 39 cases with chronic liver disease. BDAs were divided into the EMA-cytoplasmic type (n = 14)...

journal_title：Pathology international

authors： Aishima S,Tanaka Y,Kubo Y,Shirabe K,Maehara Y,Oda Y

更新日期：2014-11-01 00:00:00

abstract：:Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare, recently recognized neoplasm occurring predominantly in the subcutaneous tissue of the lower limbs of adults. We report a case of PHAT in an 83-year-old woman who presented with a 5.0 x 5.0 x 2.0 cm mass in the soft part of her left thigh. Histologically, the...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T

更新日期：2002-10-01 00:00:00

abstract：:Many reports have suggested a strong correlation between certain lectin-binding patterns and biological behavior in various tumors. To clarify a relationship between lectin-binding reactivity and survival of patients with diffuse large B-cell lymphoma (B-DLCL), 57 cases with B-DLCL were analyzed by lectin histochemist...

journal_title：Pathology international

authors： Suzuki O,Nozawa Y,Kawaguchi T,Abe M

更新日期：1999-10-01 00:00:00

abstract：:Histological grading of prostate cancer is one of the most important tissue-based parameters for prediction of outcome and treatment response. Gleason grading remains the foundation of prostate cancer grading, but has undergone a series of changes in the past 30 years, often initiated by consensus conference decisions...

journal_title：Pathology international

authors： Egevad L,Delahunt B,Yaxley J,Samaratunga H

更新日期：2019-02-01 00:00:00

abstract：:Immunohistochemical and clinicopathological features of 58 gastrointestinal stromal tumors (GIST) were studied. One occurred in the esophagus, 41 in the stomach, nine in the small intestine, and seven in the large intestine. By using indirect immunoperoxidase staining for Cajal cell markers (c-kit protein and CD34), s...

journal_title：Pathology international

authors： Tazawa K,Tsukada K,Makuuchi H,Tsutsumi Y

更新日期：1999-09-01 00:00:00

abstract：:A unique case of duodenal stromal tumor in a 51-year-old man is reported. The tumor histologically showed spindle cell proliferation and numerous eosinophilic globules. Most globules were composed of tangled 45 nm thick fibrils, which were ultrastructurally identical to 'skeinoid fibers'. The presence of glycogen gran...

journal_title：Pathology international

authors： Matsukuma S,Doi M,Suzuki M,Ikegawa K,Sato K,Kuwabara N

更新日期：1997-11-01 00:00:00

abstract：:A multi-institutional study 'Pathobiological Determinants of Atherosclerosis in Youth' (PDAY) was initiated to document the natural history of atherosclerosis, its relationship to risk factors, and pathobiology of lesion development in young subjects. Pathology laboratories in nine centers collected arteries and tissu...

journal_title：Pathology international

authors： Strong JP,Malcom GT,Oalmann MC

更新日期：1995-06-01 00:00:00

abstract：:Nuclear pseudoinclusions (NPIs) are classically found in papillary thyroid carcinoma and meningioma. Although NPIs have been described in melanocytic lesions, there is no systematic analysis of potential relationship between NPIs and other clinicopathological characteristics of melanoma. We examined the presence of NP...

journal_title：Pathology international

authors： Donizy P,Kaczorowski M,Biecek P,Halon A,Matkowski R

更新日期：2018-02-01 00:00:00

abstract：:A 51-year-old woman with a history of eating raw fish over a period of 2 weeks developed a progressive abdominal pain and leukocytosis with signs of small bowel obstruction. Eosinophilia was not detected in the peripheral blood. The patient underwent surgery to clarify the possibility of ileus. Partial small bowel nea...

journal_title：Pathology international

authors： Masui N,Fujima N,Hasegawa T,Kigawa S,Kagei N,Nagashima K,Shimizu Y

更新日期：2006-06-01 00:00:00

abstract：:Reported herein are seven cases of a histologically distinct oncocytic papillary renal cell carcinoma (OPRCC) with an inverted nuclear pattern. To define its prognostic significance, the clinicopathological features of OPRCC were compared to those of types 1 and 2 PRCC. The median age of the seven patients was 67 year...

journal_title：Pathology international

authors： Park BH,Ro JY,Park WS,Jee KJ,Kim K,Gong G,Cho YM

更新日期：2009-03-01 00:00:00

abstract：:Conditions of preserving DNA, RNA and protein in pathological specimens are of great importance as degradation of such macromolecules would critically affect results of molecular biological analysis. The feasibility of freeze-drying as a means of preserving pathological tissue samples for molecular analysis has previo...

journal_title：Pathology international

authors： Matsuo S,Sugiyama T,Okuyama T,Yoshikawa K,Honda K,Takahashi R,Maeda S

更新日期：1999-05-01 00:00:00

abstract：:We have reported that the function of histamine and its receptors (HRs) has a close relationship with the development of nonalcoholic fatty liver disease (NAFLD). However, much less is known regarding its pathogenic and molecular mechanism(s), including the early stage of hepatic and intestinal function for lipid and ...

journal_title：Pathology international

authors： Yamada S,Guo X,Wang KY,Tanimoto A,Sasaguri Y

更新日期：2016-07-01 00:00:00

abstract：:An unusual case of adenoid cystic carcinoma arising from the palatal minor salivary gland in a 63-year-old Japanese female is reported. In addition to the characteristic histopathologic features of adenoid cystic carcinoma, spindle- and dendritic-shaped cells containing excessive amounts of melanin pigment were densel...

journal_title：Pathology international

authors： Takeda Y

更新日期：1996-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV) infection is associated with pathogenesis of various cancers, including extranodal natural killer/T-cell lymphoma, nasal type (ENKL). ENKL tumor cells are positive for EBV-encoded RNA1 (EBER1), which is the most useful marker to identify ENKL tumor cells in histopathology. Currently, EBER1 in ...

journal_title：Pathology international

authors： Ito Y,Makita S,Maeshima AM,Hatta S,Yuda S,Suzuki T,Fukuhara S,Munakata W,Taniguchi H,Suzuki T,Maruyama D,Izutsu K

更新日期：2019-07-01 00:00:00