Immunohistochemical expression of gonadotropin releasing hormone receptor in human breast carcinoma.

abstract：:Angiomyxomas are a group of relatively rare mesenchymal myxoid tumors. Three types of angiomyxomas have been identified: superficial angiomyxoma, aggressive angiomyxoma and angiomyofibroblastoma. These tumors have a predilection for occurring in the perineum of middle-aged females and are often clinically diagnosed as...

journal_title：Pathology international

authors： Ustun C,Malazgirt Z,Kandemir B,Kocak I,Bolat I,Gumus S

更新日期：1998-12-01 00:00:00

abstract：:Differentiation of malignant pleural mesothelioma (MPM) from benign mesothelial proliferation remains problematic. Loss of nuclear staining of BRCA1-associated protein 1 (BAP1; detected using immunohistochemistry (IHC)) and homozygous deletion (HD) of p16 (detected using fluorescence in situ hybridization (FISH)) are ...

journal_title：Pathology international

authors： Hida T,Hamasaki M,Matsumoto S,Sato A,Tsujimura T,Kawahara K,Iwasaki A,Okamoto T,Oda Y,Honda H,Nabeshima K

更新日期：2016-10-01 00:00:00

abstract：:An autopsy case of giant cell myocarditis (GCM) in a 74-year-old woman is presented. She suffered from hepatic dysfunction, skin eruption and disseminated intravascular coagulation due to the side-effects of a non-steroidal anti-inflammatory drug. After admission, heart failure progressed rapidly, and the patient died...

journal_title：Pathology international

authors： Adachi Y,Yasumizu R,Hashimoto F,Otsuka Y,Okamura A,Kato Y,Oyaizu H,Ikebukuro K,Fukuhara S,Nakai Y,Ikehara S

更新日期：2001-02-01 00:00:00

abstract：:Reported herein is a case of medulloblastoma with myogenic differentiation in a 3-year-old girl who died 1 year after appearance of clinical signs. Magnetic resonance imaging indicated a mass lesion in the cerebellar vermis. She underwent total resection of the tumor, followed by chemotherapy and radiotherapy in the b...

journal_title：Pathology international

authors： Kido M,Ueno M,Onodera M,Matsumoto K,Imai T,Haba R,Tamiya T,Huang CL,Sakamoto H

更新日期：2009-04-01 00:00:00

abstract：:An extremely rare autopsy case of primary pulmonary choriocarcinoma combined with adenocarcinomatous components in a 77-year-old Japanese man is described. The patient died of rapidly progressive respiratory dysfunction without ante-mortem diagnosis. Autopsy revealed necro-hemorrhagic areas of the primary lung tumor w...

journal_title：Pathology international

authors： Yamamoto S,Tanaka H,Takeo H,Yasuda K,Mastukuma S

更新日期：2006-07-01 00:00:00

abstract：:Adenosquamous carcinoma (ASC) is a rare malignant neoplasm of the head and neck regions. We elucidated the relationship between ASC and MUC molecule expression. We selected 14 cases of ASC in the head and neck, and examined them immunohistohcmically. Seven cases of tongue, 3 cases of larynx and 4 cases of hypopharynx ...

journal_title：Pathology international

authors： Kusafuka K,Muramatsu K,Iida Y,Mori K,Miki T,Suda T,Fuke T,Kamijo T,Onitsuka T,Nakajima T

更新日期：2014-03-01 00:00:00

abstract：:An unusual case of adenoid cystic carcinoma arising from the palatal minor salivary gland in a 63-year-old Japanese female is reported. In addition to the characteristic histopathologic features of adenoid cystic carcinoma, spindle- and dendritic-shaped cells containing excessive amounts of melanin pigment were densel...

journal_title：Pathology international

authors： Takeda Y

更新日期：1996-06-01 00:00:00

abstract：:We have previously reported the frequent occurrence of bile duct invasion by liver metastases from colorectal cancer. We found that patients with macroscopic intrabiliary cancer growth survive longer after hepatectomy than those without this feature. In the present study, we analyzed the clinicopathological features o...

journal_title：Pathology international

authors： Kubo M,Sakamoto M,Fukushima N,Yachida S,Nakanishi Y,Shimoda T,Yamamoto J,Moriya Y,Hirohashi S

更新日期：2002-08-01 00:00:00

abstract：:A case of small intestinal extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with monoclonal cryoglobulinemia is described. The patient was a woman in her mid-sixties with purpura of the bilateral lower legs and abdominal pain. An immunoserological investigation showed expre...

journal_title：Pathology international

authors： Saito T,Tamaru J,Kishi H,Kayao J,Kuzuu Y,Wakita H,Adachi A,Itoyama S,Mikata I

更新日期：2004-09-01 00:00:00

abstract：:A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed. A small pleural nodule was incidentally found during a thoracic operation in a 54-year-old woman with esophageal cancer. The patient had no history of exposure to asbestos, and ...

journal_title：Pathology international

authors： Minato H,Nojima T,Kurose N,Kinoshita E

更新日期：2009-08-01 00:00:00

abstract：:A bilateral ovarian tumor composed of mixed Brenner tumor and struma ovarii in the right ovary and mature cystic teratoma in the left ovary, is described. Mixed Brenner tumor and struma ovarii is rare; eight cases are reviewed. In this case, in addition to the typical Brenner tumor and struma ovarii, some nests compos...

journal_title：Pathology international

authors： Yoshida M,Obayashi C,Tachibana M,Minami R

更新日期：2004-10-01 00:00:00

abstract：:A case of renal adenomatosis of the left kidney associated with a carcinoma of the ipsilateral ureter in a 49-year-old man is examined. One hundred and eight adenomas, which were smaller than 15 mm in diameter, and a single microcarcinoma, which measured 1 mm in diameter, were found in the kidney. Further, there were ...

journal_title：Pathology international

authors： Kizaki T,Ugai K,Hirano H,Gohji K,Fujii A

更新日期：1999-03-01 00:00:00

abstract：:A 56-year-old male treated for a gastric yolk sac tumor with an adenocarcinomatous component is described. A mixed area of reticular and glandular neoplastic components was morphologically identified in this tumor. Immunohistochemically, the yolk sac tumor expressed alpha-fetoprotein (AFP), placental alkaline phosphat...

journal_title：Pathology international

authors： Suzuki T,Kimura N,Shizawa S,Yabuki N,Yamaki T,Sasano H,Nagura H

更新日期：1999-06-01 00:00:00

abstract：:Leiomyomatosis peritonealis disseminata (LPD) is a rare clinicopathological entity typically observed in women of reproductive age. We report a case of LPD with malignant change in a man. A 77-year-old man presented with a mass measuring 10 cm in diameter at the terminal ileum and numerous peritoneal small nodules tha...

journal_title：Pathology international

authors： Yamaguchi T,Imamura Y,Yamamoto T,Fukuda M

更新日期：2003-03-01 00:00:00

abstract：:Bcl-6 protein is a recently identified novel transcription factor whose deregulated expression is associated with diffuse large B cell lymphomas. It was recently shown by us that the protein is located in germinal center B cells and their neoplastic counterparts. In the present study, the expression of bcl-6 protein o...

journal_title：Pathology international

authors： Kanazawa N,Moriyama M,Onizuka T,Sugawara K,Mori S

更新日期：1997-09-01 00:00:00

abstract：:We have reported that the function of histamine and its receptors (HRs) has a close relationship with the development of nonalcoholic fatty liver disease (NAFLD). However, much less is known regarding its pathogenic and molecular mechanism(s), including the early stage of hepatic and intestinal function for lipid and ...

journal_title：Pathology international

authors： Yamada S,Guo X,Wang KY,Tanimoto A,Sasaguri Y

更新日期：2016-07-01 00:00:00

abstract：:The incidence of lymphoma has rapidly increased over the last 40 years in Japan, following a trend that is very similar to that of breast cancer. In particular, the relative frequency of follicular lymphoma (FL) has reached that in Western countries. Given its indolence, a "watch-and-wait" approach is often applied to...

journal_title：Pathology international

authors： Yoshino T,Takata K,Tanaka T,Sato Y,Tari A,Okada H

更新日期：2018-12-01 00:00:00

abstract：:We compared the c-erbB-2 protein overexpression status detected by the HercepTestTM (DAKO A/S, Grostrup, Denmark) with another conventional immunohistochemistry system using an anti-c-erbB-2 rabbit polyclonal antibody (Nichirei Co., Tokyo, Japan) and with the c-erbB-2 gene amplification status detected by Southern blo...

journal_title：Pathology international

authors： Tsuda H,Tani Y,Hasegawa T,Fukutomi T

更新日期：2001-01-01 00:00:00

abstract：:Presented herein are two unusual epithelioid angiomyolipomas (AML) displaying prominent stromal sclerosis. Both patients were middle-aged women without a clinical history of tuberous sclerosis. One patient (case 1) had a 2 cm lesion arising in the renal cortex, and another (case 2) had a pararenal retroperitoneal tumo...

journal_title：Pathology international

authors： Matsuyama A,Hisaoka M,Ichikawa K,Fujimori T,Udo K,Uchihashi K,Aoki S,Hashimoto H

更新日期：2008-05-01 00:00:00

abstract：:This is the first report of segmental arterial mediolysis (SAM) accompanied with polyarteritis nodosa (PN), and manifesting aneurysms of the renal arteries. A 73-year-old woman was admitted to hospital because of a high fever. Laboratory tests showed leukocytosis with increased CRP level in the serum. Myeloperoxidase-...

journal_title：Pathology international

authors： Soga Y,Nose M,Arita N,Komori H,Miyazaki T,Maeda T,Furuya K

更新日期：2009-03-01 00:00:00

abstract：:Eosinophilic hyaline inclusions were consistently seen in the perinuclear cytoplasm of suprabasal keratinocytes in lichen amyloidosus. The inclusions, negative with amyloid staining, were immunoreactive for ubiquitin and cytokeratin, and ultrastructurally showed aggregations of fine filaments of two sizes (central thi...

journal_title：Pathology international

authors： Akamatsu M,Hori S,Tsutsumi Y,Osamura RY,Ohkido M

更新日期：1995-02-01 00:00:00

abstract：:Diffuse pulmonary ossification (DPO) is a rare condition characterized by diffuse metaplastic bone formation in the lungs. Two patterns have been described: dendriform, with a coral-like network of bone spiculae along the alveolar septa; and nodular, with lobulated fragments in the alveolar spaces. Dendriform DPO is f...

journal_title：Pathology international

authors： Porzionato A,Macchi V,Da Broi U,Giraudo C,Miotto D,Rodriguez D,Moreschi C,De Caro R

更新日期：2015-01-01 00:00:00

abstract：:A case of lymphoid hyperplasia arising in the large intestine of a 54-year-old woman is described. Barium enema X-ray and colonoscopic examination revealed multiple small polyps in the right side of the colon. Pathological findings from forceps biopsy revealed similar features to a mucosa-associated lymphoid tissue (M...

journal_title：Pathology international

authors： Nagaoka S,Bandoh T,Takemura T

更新日期：2000-09-01 00:00:00

abstract：:Morphologic features and neoplastic potentials of bile duct adenoma (BDA) and von Meyenburg complex (VMC)-like duct arising in chronic liver disease were unknown. Thirty-five BDAs and 12 VMC-like duct lesions were observed in 39 cases with chronic liver disease. BDAs were divided into the EMA-cytoplasmic type (n = 14)...

journal_title：Pathology international

authors： Aishima S,Tanaka Y,Kubo Y,Shirabe K,Maehara Y,Oda Y

更新日期：2014-11-01 00:00:00

abstract：:Chronic active Epstein-Barr virus infection (CAEBV) is a syndrome that takes diverse clinical courses and is often associated with lymphoproliferative disorders of T/natural killer (NK)-cell lineage. We describe a patient with CAEBV associated with persistent pharyngeal ulcer, and with subsequent nasal T/NK-cell lymph...

journal_title：Pathology international

authors： Nagata H,Numata T,Konno A,Mikata I,Kurasawa K,Hara S,Nishimura M,Yamamoto K,Shimizu N

更新日期：2001-10-01 00:00:00

abstract：:We report a rare case of hepatocellular carcinoma (HCC) with an unusual neuroendocrine component. During a follow-up study for chronic hepatitis C in a 71-year-old man, a nodular lesion showed rapid growth from 1 cm to 4 cm in diameter within 3 months. Histologically, the tumor was consistent with moderately different...

journal_title：Pathology international

authors： Yamaguchi R,Nakashima O,Ogata T,Hanada K,Kumabe T,Kojiro M

更新日期：2004-11-01 00:00:00

abstract：:Infantile myofibromatosis (IM) is a rare disorder present at birth or in early infancy with a biphasic histological pattern. We present a neonatal-onset case of generalized IM with visceral (central nervous system, heart, lungs, liver, spleen, small intestine, kidneys and bones) and placental involvement, showing a mo...

journal_title：Pathology international

authors： Iwafuchi H,Tsuzuki T,Ito R,Miyake H,Okita H,Hamazaki M

更新日期：2015-08-01 00:00:00

abstract：:We have found that the MIB-1 grade, based on tumor differentiation/histological type, necrosis and Ki-67 (MIB-1) score, is a valid and reproducible prognostic system for adult soft-tissue sarcomas. However, there are limited data available on Ki-67 labeling indices (LI) from adult soft-tissue sarcomas for testing the ...

journal_title：Pathology international

authors： Hasegawa T,Yamamoto S,Matsuno Y

更新日期：2002-07-01 00:00:00

abstract：:Epithelioid angiomyolipoma (eAMLoma) is an uncommon renal mesenchymal tumor with malignant potential and is frequently associated with tuberous sclerosis (TSC). It is composed of polygonal large-sized tumor cells arranged in an epithelioid manner. Differential diagnosis from renal cell carcinoma (RCC) is often challen...

journal_title：Pathology international

authors： Kato I,Inayama Y,Yamanaka S,Ohshiro H,Gomi K,Shirai S,Aoki I,Uemura H,Miyoshi Y,Kubota Y,Yao M,Nagashima Y

更新日期：2009-01-01 00:00:00

abstract：:We investigated the diagnostic and prognostic value of p53 expression and proliferative activity, as indicated by the Ki-67, in endoscopic biopsy specimens. Specimens were immunologically stained with p53 and MIB-1 (Ki-67), and the MIB-1/Ki-67 labeling index (LI) was calculated. Classification of adenomas was based on...

journal_title：Pathology international

authors： Kubota K,Kakuta Y,Kawamura S,Saito S,Seki H,Kuniyoshi T

更新日期：2003-06-01 00:00:00