Abstract:
:An autopsy case of giant cell myocarditis (GCM) in a 74-year-old woman is presented. She suffered from hepatic dysfunction, skin eruption and disseminated intravascular coagulation due to the side-effects of a non-steroidal anti-inflammatory drug. After admission, heart failure progressed rapidly, and the patient died suddenly. At autopsy, her heart was slightly enlarged and the heart muscle was thickened with many small whitish nodules. She was diagnosed with GCM because of the infiltration of multinuclear giant cells, histiocytes, eosinophils and lymphocytes into the heart. We did not find any similar lesions in any other organs. Giant cell myocarditis, the etiology of which is not defined, is a rare disease with unfavorable prognosis. This case suggests the possibility of drug-induced GCM.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Adachi Y,Yasumizu R,Hashimoto F,Otsuka Y,Okamura A,Kato Y,Oyaizu H,Ikebukuro K,Fukuhara S,Nakai Y,Ikehara Sdoi
10.1046/j.1440-1827.2001.01166.xsubject
Has Abstractpub_date
2001-02-01 00:00:00pages
113-7issue
2eissn
1320-5463issn
1440-1827pii
pin1166journal_volume
51pub_type
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