Abstract:
:Mucinous cystic neoplasm (MCN) of the pancreas is characterized by mucin-producing columnar epithelium and an ovarian-type stroma. It occurs almost exclusively in women and is almost always located in the pancreatic body or tail. Here, we report a case of large MCN located in the pancreatic head but not in the body nor tail in a 32-year-old pregnant woman, which was thought to have grown rapidly during pregnancy. It was ruptured at 34 weeks of gestation and the patient was admitted to the emergency department of the University of Fukui Hospital with an acute abdomen. Emergency cesarean section followed by pancreaticoduodenectomy was performed. The tumor consisted of many small cysts lined by a single-layer of mucinous epithelium with papillary growth and partial solid parts showing invasive growth and sarcomatoid changes, indicating mucinous cystic neoplasm with an associated invasive carcinoma (previously referred as mucinous cystadenocarcinoma). Thickened septa revealed ovarian-type stroma strongly positive for α-inhibin and partly positive for progesterone receptor immunohistochemically. We also review and discuss previous reports of MCNs including those with an associated invasive carcinoma in pregnant patients.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Naganuma S,Honda K,Noriki S,Kimura S,Murakami M,Koneri K,Katayama K,Yamaguchi A,Itoh Hdoi
10.1111/j.1440-1827.2010.02609.xsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
28-33issue
1eissn
1320-5463issn
1440-1827journal_volume
61pub_type
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