Prognostic significance of gastric cancer metastasis in second-tier lymph nodes detected on reverse transcriptase-polymerase chain reaction and immunohistochemistry.

abstract：:The localization of glutathione peroxidase (GSH-PO) in the human arteriosclerotic lesions was investigated by immunohistochemical methods. GSH-PO is an enzyme that effectively reduces lipid peroxides. It is also known that its synthesis is significantly increased by lipid peroxides, the substrate of the enzyme. Accord...

journal_title：Pathology international

authors： Mori I,Yoshimura S,Watanabe K

更新日期：1995-05-01 00:00:00

abstract：:We compared the c-erbB-2 protein overexpression status detected by the HercepTestTM (DAKO A/S, Grostrup, Denmark) with another conventional immunohistochemistry system using an anti-c-erbB-2 rabbit polyclonal antibody (Nichirei Co., Tokyo, Japan) and with the c-erbB-2 gene amplification status detected by Southern blo...

journal_title：Pathology international

authors： Tsuda H,Tani Y,Hasegawa T,Fukutomi T

更新日期：2001-01-01 00:00:00

abstract：:Metallothionein (MT) has been reported to play important physiological roles in the human body, but the distribution and significance of MT is not fully understood. In order to analyze MT expression, three kinds of polyclonal MT fragment antibodies were developed against NH2-terminal, middle regional and COOH-terminal...

journal_title：Pathology international

authors： Nakazato K,Nakajima K,Kusakabe T,Suzuki K,Nagamine T

更新日期：2008-12-01 00:00:00

abstract：:Homozygous deletion of 9p21, the locus harboring the p16 gene, has been reported as one of the most common genetic alterations in malignant mesotheliomas (MMs). Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens. ...

journal_title：Pathology international

authors： Takeda M,Kasai T,Enomoto Y,Takano M,Morita K,Kadota E,Nonomura A

更新日期：2010-05-01 00:00:00

abstract：:Anomalous pancreaticobiliary junction (APBJ) is a congenital anomaly in which the pancreatic duct joins the common bile duct proximal to the sphincter of Oddi. Anatomical and immunohistochemical examination of the pancreas with APBJ has rarely been performed. A 72-year-old woman with gallbladder cancer and APBJ died o...

journal_title：Pathology international

authors： Tadokoro H,Takase M,Nobukawa B

更新日期：2008-08-01 00:00:00

abstract：:Myofibroblasts have ultrastructural and functional characteristics intermediate between fibroblasts and smooth muscle cells. Previous studies indicated that most myofibroblasts express actin and vimentin but not desmin immunophenotypes. Two benign intramuscular myofibroblastic tumors which displayed a desmin-positive ...

journal_title：Pathology international

authors： Yang P,Hirose T,Seki K,Hasegawa T,Hizawa K,Sano T

更新日期：1996-09-01 00:00:00

abstract：:We report a case of glomerular cystic kidney disease (GCKD) associated with tuberous sclerosis complex (TSC) in a neonate. The patient displayed progressive abdominal enlargement attributed to GCKD associated with TSC. After birth, the right kidney was resected because it compressed his liver and right lung, and possi...

journal_title：Pathology international

authors： Murakami A,Gomi K,Tanaka M,Ohyama M,Itani Y,Ishikawa H,Aida N,Furuya M,Tanaka Y

更新日期：2012-03-01 00:00:00

abstract：:This report presents a case of neural fibrolipoma arising from the superficial peroneal nerve in the ankle. A 28-year-old woman was referred with a soft tissue mass in the anterior aspect of the right ankle, which had been gradually enlarging for the past 10 years. Magnetic resonance imaging showed a mass lesion, meas...

journal_title：Pathology international

authors： Akisue T,Matsumoto K,Yamamoto T,Kizaki T,Fujita I,Yoshiya S,Kurosaka M

更新日期：2002-11-01 00:00:00

abstract：:Pulmonary alveolar proteinosis (PAP) is a rare condition in which pulmonary macrophages fail to clear surfactant, resulting in the alveolar accumulation of lipoproteinaceous debris. The histopathology of PAP is typified by diffuse filling of terminal airways with eosinophilic, PAS/diastase (PAS/D)-positive acellular m...

journal_title：Pathology international

authors： Nishino M,Medoff BD,Mark EJ,Matsubara O,O'Donnell WJ,Currier PF,Kradin RL

更新日期：2011-09-01 00:00:00

abstract：:The juxtaglomerular cell tumor (JGCT) of the kidney is a rare neoplasm which commonly secretes renin. This tumor often occurs in teenagers. This paper documents the 14th adult-onset (over 30-years-old) case with a giant JGCT which measured 9.0 x 8.0 x 7.5 cm. Histologically, this tumor was composed of both vascular an...

journal_title：Pathology international

authors： Kuroda N,Moriki T,Komatsu F,Miyazaki E,Hayashi Y,Naruse K,Nakayama H,Kiyoku H,Hiroi M,Shuin T,Enzan H

更新日期：2000-03-01 00:00:00

abstract：:Herein is presented a case of carcinosarcoma of the pancreas in an 82-year-old woman, analyzed on immunohistochemistry and K-ras sequence. The tumor, which arose in the pancreas head, was removed on pancreaticoduodenectomy. The patient died, however, of disseminated intravascular coagulation syndrome from postoperativ...

journal_title：Pathology international

authors： Nakano T,Sonobe H,Usui T,Yamanaka K,Ishizuka T,Nishimura E,Hanazaki K

更新日期：2008-10-01 00:00:00

abstract：:The clinicopathological significance of colonic and small-intestinal phenotypes has hitherto remained unclear in gastric cancers. The purpose of the present study was therefore to examine 86 gastric carcinomas histologically and phenotypically using several phenotypic markers, including colon-specific carbonic anhydra...

journal_title：Pathology international

authors： Mizoshita T,Tsukamoto T,Tanaka H,Takenaka Y,Kato S,Cao X,Joh T,Tatematsu M

更新日期：2005-10-01 00:00:00

abstract：:To examine the relationship between the scavenger receptor A (SRA) index (the number of SRA+ cells observed in 10 high power fields of peripheral blood (PB) smear samples; normal upper limit <30) and coronary thrombus, 389 thrombi obtained from 393 patients with acute ST elevation myocardial infarction were examined. ...

journal_title：Pathology international

authors： Emura I,Usuda H,Fujita T,Ebe K,Nagai T

更新日期：2011-06-01 00:00:00

abstract：:One hundred and fifteen patients with chronic hepatitis C were administered interferon (IFN) and classed into two groups: (i) complete responders (CR), HCV-RNA continuously negative 1 year after treatment; and (ii) non-responders (NR), positive 1 year after treatment. Multivariate analysis comprised eight variables: a...

journal_title：Pathology international

authors： Kim SR,Hayashi Y,Yoon S,Taniguchi M,Yang MK,Kim KI,Kim MM,Saeki K,Nukata I,Imoto S

更新日期：1998-03-01 00:00:00

abstract：:Cellular senescence is defined as irreversible cell arrest and could work as a safeguard against tumorigenesis. This mechanism was examined in chronic viral hepatitis-related hepatocarcinogenesis. By using surgical resected or wedge biopsied liver specimens from 87 chronic viral hepatitis patients in whom 35 neoplasti...

journal_title：Pathology international

authors： Ikeda H,Sasaki M,Sato Y,Harada K,Zen Y,Mitsui T,Nakanuma Y

更新日期：2009-07-01 00:00:00

abstract：:Nuclear pseudoinclusions (NPIs) are classically found in papillary thyroid carcinoma and meningioma. Although NPIs have been described in melanocytic lesions, there is no systematic analysis of potential relationship between NPIs and other clinicopathological characteristics of melanoma. We examined the presence of NP...

journal_title：Pathology international

authors： Donizy P,Kaczorowski M,Biecek P,Halon A,Matkowski R

更新日期：2018-02-01 00:00:00

abstract：:A 53-year-old woman presented with Cushing's syndrome resulting from an adrenocortical adenoma, 6.5 cm in diameter and 75 g in weight, which is larger than usual. Endocrinological data of this patient showed adrenocorticotropin (ACTH)-independent hypercortisolemia. A computed tomography scan of the adrenal glands reve...

journal_title：Pathology international

authors： Karasawa R,Hotta M,Aiba M,Takano K

更新日期：2004-04-01 00:00:00

abstract：:We previously reported that detection of desmoplastic reaction (DR) in pretreatment biopsy specimens was useful for predicting the depth of submucosal invasion (SM depth) in nonpedunculated early colorectal cancers (ECRCs) in a retrospective study. Here, we performed a prospective multicenter study for verification of...

journal_title：Pathology international

authors： Kimura R,Fujimori T,Ichikawa K,Ajioka Y,Ueno H,Ohkura Y,Kashida H,Togashi K,Yao T,Wada R,Watanabe T,Ochiai A,Sugai T,Sugihara K,Igarashi Y

更新日期：2012-08-01 00:00:00

abstract：:Secondary (metastatic) neoplasms to the ovary often cause diagnostic problems, especially those tumors that produce large, symptomatic ovarian tumors that masquerade clinically and pathologically as primary ovarian tumors of surface epithelial type. Most of these tumors arise from organs of the digestive system. Excep...

journal_title：Pathology international

authors： Hart WR

更新日期：2005-05-01 00:00:00

abstract：:The aim of the present study was to clarify protein profiling in small cell lung carcinoma (SCLC) and pulmonary large cell neuroendocrine carcinoma (LCNEC). The proteomic approach was used, and involved cell lysate from two cell lines (N231 derived from SCLC and LCN1 derived from LCNEC), with 2-D gel electrophoresis (...

journal_title：Pathology international

authors： Nagashio R,Sato Y,Matsumoto T,Kageyama T,Satoh Y,Ryuge S,Masuda N,Jiang SX,Okayasu I

更新日期：2010-02-01 00:00:00

abstract：:We report a case of a 57-year-old man who developed a fibrosclerosing lesion in the submandibular gland and idiopathic retroperitoneal fibrosis (IRF) involving the unilateral periureteral region within a year. Both lesions were resected surgically because of the suspicion of neoplasm. Pathologic examination revealed s...

journal_title：Pathology international

authors： Sekine S,Nagata M,Watanabe T

更新日期：1999-07-01 00:00:00

abstract：:Infarction of a breast fibroadenoma usually occurs in young females during pregnancy or lactation. This report describes a rare case of the total infarction of a fibroadenoma in a 58 year old postmenopausal woman. The chief complaint was a rapidly enlarged, slightly painful lump. Medullary carcinoma was suspected on p...

journal_title：Pathology international

authors： Ichihara S,Matsuyama T,Kubo K,Tamura Z,Aoyama H

更新日期：1994-05-01 00:00:00

abstract：:Changes in cerebrospinal fluid (CSF) composition have been shown to accurately reflect pathological processes in the CNS, and are potential indicators of abnormal CNS states, such as tumor growth. To detect biomarkers in high-grade astrocytomas, the differential expression of proteins in the cerebrospinal fluid was an...

journal_title：Pathology international

authors： Ohnishi M,Matsumoto T,Nagashio R,Kageyama T,Utsuki S,Oka H,Okayasu I,Sato Y

更新日期：2009-11-01 00:00:00

abstract：:A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed. A small pleural nodule was incidentally found during a thoracic operation in a 54-year-old woman with esophageal cancer. The patient had no history of exposure to asbestos, and ...

journal_title：Pathology international

authors： Minato H,Nojima T,Kurose N,Kinoshita E

更新日期：2009-08-01 00:00:00

abstract：:The factors conferring the increased malignancy on lung adenocarcinoma with micropapillary component (AC-MPC) remain to be elucidated. On proteomics based on 2-dimensional gel electrophoresis, 19 proteins differentially expressed by more than 1.5-fold between AC-MPC and conventional adenocarcinoma (CAC); in particular...

journal_title：Pathology international

authors： Nakashima H,Jiang SX,Sato Y,Hoshi K,Matsumoto T,Nagashio R,Kobayashi M,Matsuo Y,Shiomi K,Hayakawa K,Saegusa M,Satoh Y

更新日期：2015-04-01 00:00:00

abstract：:Epilepsy presenting early in childhood may be associated with a neurologically devastating clinical course and have significant implications for the child's development. There are limited published data regarding the clinicopathological features of patients who have undergone epilepsy surgery in the first year of life...

journal_title：Pathology international

authors： Prayson RA

更新日期：2000-08-01 00:00:00

abstract：:A 51-year-old woman with a history of eating raw fish over a period of 2 weeks developed a progressive abdominal pain and leukocytosis with signs of small bowel obstruction. Eosinophilia was not detected in the peripheral blood. The patient underwent surgery to clarify the possibility of ileus. Partial small bowel nea...

journal_title：Pathology international

authors： Masui N,Fujima N,Hasegawa T,Kigawa S,Kagei N,Nagashima K,Shimizu Y

更新日期：2006-06-01 00:00:00

abstract：:BRCA1-associated protein 1 (BAP1) or methylthioadenosine phosphorylase (MTAP) immunohistochemistry (IHC) or 9p21 fluorescence in situ hybridization (FISH) are useful for the diagnosis of malignant pleural mesothelioma (MPM). However, the effect of these assays on the diagnostic yield of effusion cytology in MPM cases ...

journal_title：Pathology international

authors： Kinoshita Y,Hamasaki M,Matsumoto S,Yoshimura M,Sato A,Tsujimura T,Kamei T,Kawahara K,Nabeshima K

更新日期：2020-09-01 00:00:00

abstract：:The histology of basaloid squamous cell carcinoma (BSCC) can resemble that of adenoid cystic carcinoma (AdCC). Herein, we report two cases of BSCC with adenoid cystic-like features (BSCC-AdC). We collected cases of AdCC and BSCC of the head and neck region, extracted two cases with unusual histology, and reexamined th...

journal_title：Pathology international

authors： Kusafuka K,Yagi H,Baba S,Inagaki H,Tsuchiya C,Hirata K,Muramatsu A,Suzuki M,Arai K,Terada T

更新日期：2020-10-01 00:00:00

abstract：:Malignant transformation of ovarian mature cystic teratomas is reported to occur in about 1% of cases. The most common malignant evolution is that of squamous cell carcinoma and one of the least common is that of small cell carcinoma. We report a case of distant metastasis from a small cell carcinoma arising in a matu...

journal_title：Pathology international

authors： Lim SC,Choi SJ,Suh CH

更新日期：1998-10-01 00:00:00