Abstract:
:This report presents a case of neural fibrolipoma arising from the superficial peroneal nerve in the ankle. A 28-year-old woman was referred with a soft tissue mass in the anterior aspect of the right ankle, which had been gradually enlarging for the past 10 years. Magnetic resonance imaging showed a mass lesion, measuring approximately 8 x 3 x 2 cm, with high to partially low signal intensity on both T1- and T2-weighted images. A band of low signal intensity within the lesion, which is indicative of coexistence with the tumor and the superficial peroneal nerve, could be detected on both T1- and T2-weighted images. The patient underwent an excisional biopsy. The specimen microscopically consisted of nerve bundles and fibro-fatty proliferation with abundant collagen fibers. Immunoreactivity for CD34 antigen antibody was detected in fibrous spindle cells. This is the first report to present an immunohistochemical profile of neural fibrolipoma. Neural fibrolipoma should be considered as a differential diagnosis when a lipomatous lesion is encountered in the foot or ankle as well as in the upper extremities.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Akisue T,Matsumoto K,Yamamoto T,Kizaki T,Fujita I,Yoshiya S,Kurosaka Mdoi
10.1046/j.1440-1827.2002.01412.xsubject
Has Abstractpub_date
2002-11-01 00:00:00pages
730-3issue
11eissn
1320-5463issn
1440-1827journal_volume
52pub_type
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