Three synchronous carcinomas of the papilla of Vater, common bile duct and pancreas.

abstract：:Several reports have demonstrated the use of whole-slide imaging (WSI) for primary pathological diagnosis, but no such studies have been published from Asia. We retrospectively collected 1070 WSI specimens from 900 biopsies and small surgeries conducted in nine hospitals. Nine pathologists, who participated in this st...

journal_title：Pathology international

authors： Tabata K,Mori I,Sasaki T,Itoh T,Shiraishi T,Yoshimi N,Maeda I,Harada O,Taniyama K,Taniyama D,Watanabe M,Mikami Y,Sato S,Kashima Y,Fujimura S,Fukuoka J

更新日期：2017-11-01 00:00:00

abstract：:Pilomyxoid astrocytoma, first described by Tihan et al., was recently included as an established variant of pilocytic astrocytoma in the World Health Organization classification of CNS tumors. Histologically, it much resembles pilocytic astrocytoma, but monomorphic myxoid tumor of pilocytic cells with prominent angioc...

journal_title：Pathology international

authors： Amatya VJ,Akazawa R,Sumimoto Y,Takeshima Y,Inai K

更新日期：2009-02-01 00:00:00

abstract：:The chemokine receptor CXCR4 belongs to the large superfamily of G protein-coupled receptors and has been identified to play a crucial role in a number of biological processes, including the trafficking and homeostasis of immune cells such as T lymphocytes. CXCR4 has also been found to be a prognostic marker in variou...

journal_title：Pathology international

authors： Furusato B,Mohamed A,Uhlén M,Rhim JS

更新日期：2010-07-01 00:00:00

abstract：:The factors conferring the increased malignancy on lung adenocarcinoma with micropapillary component (AC-MPC) remain to be elucidated. On proteomics based on 2-dimensional gel electrophoresis, 19 proteins differentially expressed by more than 1.5-fold between AC-MPC and conventional adenocarcinoma (CAC); in particular...

journal_title：Pathology international

authors： Nakashima H,Jiang SX,Sato Y,Hoshi K,Matsumoto T,Nagashio R,Kobayashi M,Matsuo Y,Shiomi K,Hayakawa K,Saegusa M,Satoh Y

更新日期：2015-04-01 00:00:00

abstract：:A case of a 66-year-old Japanese woman with two synchronous urinary bladder tumors, namely verrucous carcinoma and poorly differentiated squamous cell carcinoma, is described. Both tumors were accompanied by widespread squamous metaplasia in the background and unassociated with bilharzial infection. The poorly differe...

journal_title：Pathology international

authors： Oida Y,Yasuda M,Kajiwara H,Onda H,Kawamura N,Osamura RY

更新日期：1997-09-01 00:00:00

abstract：:Telomerase activity is thought to contribute to the immortality of cancers. Recently, some investigators described a correlation between the activity of telomerase and the proliferative activity of cancer cells. The aim of this study was to evaluate the correlation between the expression of telomerase-associated prote...

journal_title：Pathology international

authors： Ikeda S,Shibata T,Eishi Y,Takizawa T,Koike M

更新日期：2003-11-01 00:00:00

abstract：:Malignant lymphoma arising in the stomach of a 23-year-old Japanese man with systemic sarcoidosis is presented. The patient was followed because of systemic sarcoidosis involving the lungs, eyes, and lymph nodes. Biopsy specimens from the stomach were repeated because of recurrent epigastralgia and multiple ulceration...

journal_title：Pathology international

authors： Fukuda T,Sato K,Tachikawa S,Ohnuki K,Ohtani H,Suzuki T

更新日期：1997-12-01 00:00:00

abstract：:The aims of this study were to identity the roles of tumor vessels and hormone receptor status in normal, hyperplastic, and neoplastic endometrium, and to explore their relationships with other prognostic factors of endometrial adenocarcinoma. Endometrial curettage specimens of proliferative phase and secretory phase ...

journal_title：Pathology international

authors： Nunobiki O,Taniguchi E,Ishii A,Tang W,Utsunomiya H,Nakamura Y,Mori I,Kakudo K

更新日期：2003-12-01 00:00:00

abstract：:A cytometrical image analyzing method for nuclear protein was established using WinROOF, a commercially available, inexpensive software, to determine the status of both estrogen and progesterone receptors. Immunohistochemical evaluation of estrogen receptors (ER) and progesterone receptors (PR) was performed with the ...

journal_title：Pathology international

authors： Hatanaka Y,Hashizume K,Nitta K,Kato T,Itoh I,Tani Y

更新日期：2003-10-01 00:00:00

abstract：:Elastosis is the pathological finding of focal deposits of elastic fibers in abnormal amounts within tissue. It is well described in the case of infiltrating carcinoma of the breast, but elastosis in lung carcinoma has not been previously documented in detail. We investigated the characteristics of elastosis in lung c...

journal_title：Pathology international

authors： Fukushima M,Fukuda Y,Kawamoto M,Yamanaka N

更新日期：2000-12-01 00:00:00

abstract：:A 15 month old female, who had suffered from ventricular tachycardia from the prenatal period, experienced cardiac arrest at home. Once she had recovered, ventricular tachycardia occurred repeatedly. She died 7 months after admission. At autopsy, the heart showed many yellowish white nodules in the endocardium. Histol...

journal_title：Pathology international

authors： Otani M,Hoshida H,Saji T,Matsuo N,Kawamura S

更新日期：1995-10-01 00:00:00

abstract：:In the present study, 62 cases of ocular adnexal lymphoproliferative disorders were reviewed clinicopathologically. Of them, 51 were extranodal marginal zone B-cell lymphoma (MALT lymphoma), five were diffuse large B-cell lymphoma (DLBCL), one was peripheral T-cell lymphoma, one was NK/T cell lymphoma, nasal type, and...

journal_title：Pathology international

authors： Adachi A,Tamaru J,Kaneko K,Kuroda H,Miura I,Kojima T,Hoshino S,Ichinohasama R,Itoyama S

更新日期：2004-01-01 00:00:00

abstract：:A case of low-grade endometrial stromal sarcoma with extensive epithelial-like element (ELE) is reported. This tumor was composed of classical endometrial stromal sarcoma (CESS) showing diffuse proliferation, and ELE occupying approximately 72% of the tumor mass. On immunohistochemistry, ELE was negative for sex-cord ...

journal_title：Pathology international

authors： Ohta Y,Suzuki T,Kojima M,Shiokawa A,Mitsuya T

更新日期：2003-04-01 00:00:00

abstract：:Reported herein is a 57-year-old man infected by Sparganum mansoni, a kind of tapeworm, showing a solitary nodule of the middle lobe of the right lung. Because a transbronchial biopsy could not diagnose the nodule, a right middle lobectomy was performed on suspicion of malignant tumor. The lesion was diagnosed as spar...

journal_title：Pathology international

authors： Iwatani K,Kubota I,Hirotsu Y,Wakimoto J,Yoshioka M,Mori T,Ito T,Nomori H

更新日期：2006-11-01 00:00:00

abstract：:A unique case of duodenal stromal tumor in a 51-year-old man is reported. The tumor histologically showed spindle cell proliferation and numerous eosinophilic globules. Most globules were composed of tangled 45 nm thick fibrils, which were ultrastructurally identical to 'skeinoid fibers'. The presence of glycogen gran...

journal_title：Pathology international

authors： Matsukuma S,Doi M,Suzuki M,Ikegawa K,Sato K,Kuwabara N

更新日期：1997-11-01 00:00:00

abstract：:Cellular senescence is defined as irreversible cell arrest and could work as a safeguard against tumorigenesis. This mechanism was examined in chronic viral hepatitis-related hepatocarcinogenesis. By using surgical resected or wedge biopsied liver specimens from 87 chronic viral hepatitis patients in whom 35 neoplasti...

journal_title：Pathology international

authors： Ikeda H,Sasaki M,Sato Y,Harada K,Zen Y,Mitsui T,Nakanuma Y

更新日期：2009-07-01 00:00:00

abstract：:Pituicytoma is a rare low-grade glial neoplasm that originates in the neurohypophysis or infundibulum. Because of its rare occurrence, the morphology and differentiation of pituicytoma have not been fully clarified. Here, we report a case of pituicytoma with unusual histological features mimicking ependymoma, but exhi...

journal_title：Pathology international

authors： Kwon MJ,Suh YL

更新日期：2011-10-01 00:00:00

abstract：:A 28-year-old woman complained of irregular menstruation. Abdominal ultrasound and magnetic resonance imaging (MRI) examinations revealed a cystic tumor in the left ovary. A histological examination of the resected ovary revealed that the lesion was a mature cystic teratoma. In this tumor, components such as skin with...

journal_title：Pathology international

authors： Kuroda N,Hirano K,Inui Y,Yamasaki Y,Toi M,Nakayama H,Hiroi M,Enzan H

更新日期：2001-11-01 00:00:00

abstract：:A case of a 9-year-old boy with fibrocartilaginous mesenchymoma located in the distal femur is presented. Fibrocartilaginous mesenchymoma is a rare tumor. There have been 17 cases reported since 1984. The presenting complaint was pain and local discomfort. Radiological examination showed lytic and sclerotic lesions lo...

journal_title：Pathology international

authors： Gedikoglu G,Aksoy MC,Ruacan S

更新日期：2001-08-01 00:00:00

abstract：:Angioleiomyoma is a solitary subcutaneous tumor characterized by pain in about half of patients with this tumor, and the pathogenesis of this pain has been a cause of much debate. To clarify the mechanism of pain and cytoskeletal property of tumor cells, 50 angioleiomyomas were studied clinicopathologically and immuno...

journal_title：Pathology international

authors： Hasegawa T,Seki K,Yang P,Hirose T,Hizawa K

更新日期：1994-01-01 00:00:00

abstract：:We present a case of uterine intravenous leiomyomatosis associated with multiple pulmonary metastases with bullae-like cystic change. A 53-year-old woman who had undergone hysterectomy 5 years previously underwent an operation for multiple pulmonary nodules with bullae formation. After resection of several large bulla...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T,Hisayoshi T,Asano G

更新日期：2001-05-01 00:00:00

abstract：:Changes in cerebrospinal fluid (CSF) composition have been shown to accurately reflect pathological processes in the CNS, and are potential indicators of abnormal CNS states, such as tumor growth. To detect biomarkers in high-grade astrocytomas, the differential expression of proteins in the cerebrospinal fluid was an...

journal_title：Pathology international

authors： Ohnishi M,Matsumoto T,Nagashio R,Kageyama T,Utsuki S,Oka H,Okayasu I,Sato Y

更新日期：2009-11-01 00:00:00

abstract：:A case of multiple myeloma, who died of congestive heart failure of unknown cause, is presented. Microscopically, Anitschkow cells with caterpillar and owl-eyed nuclei were scattered in the interstitium of the myocardium. To know the pathological significance of their appearance, histological observations of normal, d...

journal_title：Pathology international

authors： Satoh F,Tsutsumi Y

更新日期：1999-01-01 00:00:00

abstract：:Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground-glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiologi...

journal_title：Pathology international

authors： Hashimoto H,Matsumoto J,Murakami M,Hiyama N,Yamaguchi H,Kusakabe M,Horiuchi H,Morikawa T

更新日期：2020-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV) has been implicated as a causal virus of gastric cancer with episomal monoclonality, elevated antibodies and a unique morphologic expression in the early intramucosal stage, but the infection mechanisms have not been demonstrated. EBV has been shown only in the cancerous lesions by the highly ...

journal_title：Pathology international

authors： Arikawa J,Tokunaga M,Tashiro Y,Tanaka S,Sato E,Haraguchi K,Yamamoto A,Toyohira O,Tsuchimochi A

更新日期：1997-10-01 00:00:00

abstract：:One of the striking microscopic appearances of breast carcinoma is malignant transformation of the epithelium of an entire lobule, although the lobular architecture is still preserved. We termed this pathological feature 'lobular involvement'. An investigation was carried out to determine whether lobular involvement w...

journal_title：Pathology international

authors： Ishige H,Kondo Y,Yagata H,Onoki J,Suzuki M,Oshida M,Nagashima T,Hashimoto H,Nakajima N

更新日期：1999-06-01 00:00:00

abstract：:To determine the prognostic significance of the methods used to determine the presence of metastasis in second-tier lymph nodes of patients with gastric cancer, the authors studied lymph nodes surgically removed from 100 patients with gastric cancer (55 with early cancer, 45 with progressive). The results of HE staini...

journal_title：Pathology international

authors： Ikeda S,Funakoshi N,Usui S,Takiguchi N,Hiranuma S,Shibata T

更新日期：2008-01-01 00:00:00

abstract：:High-grade transformation (HGT)/dedifferentiation is an unusual phenomenon in salivary gland carcinomas. Here we report a case of adenoid cystic carcinoma (ACC) with HGT/dedifferentiation to myoepithelial carcinoma, occurring in the epipharynx of a 42-year-old woman. The surgically resected tumor was a pedunculated ma...

journal_title：Pathology international

authors： Tando S,Nagao T,Kayano K,Fushiki S,Itoh K

更新日期：2018-02-01 00:00:00

abstract：:A surgical case of inflammatory myofibroblastic tumor arising in the uterine corpus and exhibiting prominent myxoid change of the stroma is reported. The patient was a 63-year-old woman with a large tumor mass that filled the uterine cavity and measured 11 cm in maximal dimension. The tumor had a gelatinous appearance...

journal_title：Pathology international

authors： Shintaku M,Fukushima A

更新日期：2006-10-01 00:00:00

abstract：:Patients with pulmonary small cell carcinoma are well known to have a poor prognosis. However, predictors of prognosis and treatment outcome have not been reported for this type of cancer. We examined whether excision repair cross-complementation group 1 (ERCC1), phosphorylated Akt (p-Akt), phosphorylated mammalian ta...

journal_title：Pathology international

authors： Ikeda S,Takabe K,Inagaki M,Suzuki K

更新日期：2010-11-01 00:00:00