Abstract:
:Pilomyxoid astrocytoma, first described by Tihan et al., was recently included as an established variant of pilocytic astrocytoma in the World Health Organization classification of CNS tumors. Histologically, it much resembles pilocytic astrocytoma, but monomorphic myxoid tumor of pilocytic cells with prominent angiocentric growth pattern without Rosenthal fibers or eosinophilic granular bodies is characteristic of pilomyxoid astrocytoma. Pilomyxoid astrocytoma is thought to be more aggressive with more frequent local recurrence as well as cerebrospinal spread. The authors recently encountered a case of pilomyxoid astrocytoma, therefore the purpose of the present study was undertake a retrospective review of pilocytic astrocytomas previously diagnosed during the past 10 years. Consequently, two of them were found to have histological features suggestive of pilomyxoid astrocytoma and both involved multiple recurrence, suggesting aggressive behavior in comparison to pilocytic astrocytoma. Therefore, knowledge of this entity is essential to surgical pathologists and clinicians for patient management.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Amatya VJ,Akazawa R,Sumimoto Y,Takeshima Y,Inai Kdoi
10.1111/j.1440-1827.2008.02332.xsubject
Has Abstractpub_date
2009-02-01 00:00:00pages
80-5issue
2eissn
1320-5463issn
1440-1827pii
PIN2332journal_volume
59pub_type
杂志文章abstract::Infantile myofibromatosis (IM) is a rare disorder present at birth or in early infancy with a biphasic histological pattern. We present a neonatal-onset case of generalized IM with visceral (central nervous system, heart, lungs, liver, spleen, small intestine, kidneys and bones) and placental involvement, showing a mo...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12312
更新日期:2015-08-01 00:00:00
abstract::Senescence marker protein 30 (SMP 30) is preferentially expressed in the liver. One of its remarkable functions is the protection of cells against various injuries by enhancement of membrane calcium-pump activity. We analyzed the role of SMP 30 in hepatocyte proliferation. SMP 30 expression was decreased initially, th...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2001.01238.x
更新日期:2001-07-01 00:00:00
abstract::A multi-institutional study 'Pathobiological Determinants of Atherosclerosis in Youth' (PDAY) was initiated to document the natural history of atherosclerosis, its relationship to risk factors, and pathobiology of lesion development in young subjects. Pathology laboratories in nine centers collected arteries and tissu...
journal_title:Pathology international
pub_type: 杂志文章,多中心研究,评审
doi:10.1111/j.1440-1827.1995.tb03476.x
更新日期:1995-06-01 00:00:00
abstract::Epilepsy presenting early in childhood may be associated with a neurologically devastating clinical course and have significant implications for the child's development. There are limited published data regarding the clinicopathological features of patients who have undergone epilepsy surgery in the first year of life...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2000.01101.x
更新日期:2000-08-01 00:00:00
abstract::Bone morphogenetic proteins (BMPs) are multi-functional cytokines, which belong to the transforming growth factor-β (TGF-β) family. In some cancer tissues, aberrant expression of various BMP signal components has been detected. Here, we describe the divergent roles of BMPs during the progression of cancer. BMPs exhibi...
journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1111/pin.12067
更新日期:2013-06-01 00:00:00
abstract::Histiocytic necrotizing lymphadenitis is rare outside Japan, including Brazil, despite the many Japanese immigrants and descendants who live there. The authors describe the case of a 32 year old white female, who presented with cervical lymph node enlargement and severe anemia. Histological findings of the lymph node ...
journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1111/j.1440-1827.1994.tb02606.x
更新日期:1994-07-01 00:00:00
abstract::For the detection of chromosome translocations/chimeric genes and specific genetic abnormalities in soft tissue tumors, we conducted fluorescence in situ hybridization (FISH) analysis on 280 cases of soft tissue and other tumors using formalin-fixed paraffin-embedded tissue sections. The detection rate of the FISH spl...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2011.02739.x
更新日期:2012-01-01 00:00:00
abstract::The aluminum (AI) and iron (Fe) chelate complexes of nitrilotriacetate (NTA) cause renal insufficiency when they are administered intraperitoneally to rats. Their effects on bone metabolism were studied in 4 week old Wistar rats. Daily intraperitoneal administration of AI-NTA (3mg AI/kg for 11 weeks) induced osteomala...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1995.tb03375.x
更新日期:1995-01-01 00:00:00
abstract::Angiomyolipoma (AML) is a mixed mesenchymal tumor belonging to the family of perivascular epithelioid cell tumors. Concurrent development of AML and adult renal cell carcinoma (RCC) is very rare. Herein is presented a unique case in which RCC arose within a previously detected AML tumor mass. A 40-year-old woman had b...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2006.02075.x
更新日期:2007-03-01 00:00:00
abstract::An 18-year-old woman with abdominal pain was diagnosed as having splenic cysts by computed tomography scan. She had high serum levels of CA19-9 (2886.8 U/mL; normal value, <35 U/mL), CA125 (131.1 U/mL; normal value, <35 U/mL) and soluble IL-2 receptor (1490 U/mL; normal range, 220-530 U/mL). The resected spleen weighe...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2004.01630.x
更新日期:2004-05-01 00:00:00
abstract::Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare kidney neoplasm that almost exclusively occurs in perimenopausal women, and long-term estrogen replacement is relevant to its pathogenesis. Herein is described an atypical case of MESTK uncovered in a 12-year-old premenarcheal girl without a history of...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2005.01888.x
更新日期:2005-10-01 00:00:00
abstract::Angiomyxomas are a group of relatively rare mesenchymal myxoid tumors. Three types of angiomyxomas have been identified: superficial angiomyxoma, aggressive angiomyxoma and angiomyofibroblastoma. These tumors have a predilection for occurring in the perineum of middle-aged females and are often clinically diagnosed as...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1998.tb03867.x
更新日期:1998-12-01 00:00:00
abstract::The diagnosis of the rare neoplasm histiocytic sarcoma (HS) relies on morphology and the presence of immunophenotypic features of histiocytic lineage. More than 57 cases, including 16 cases involving the gastrointestinal (GI) tract, have been described since the World Health Organization issued its classification syst...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12032
更新日期:2013-02-01 00:00:00
abstract::Giant cell tumor (GCT) of bone is a primary osteolytic tumor that is characterized by the formation of osteoclast-like giant cells. In addition to GCT of bone, extraskeletal GCT are known to be formed in several soft tissues. Giant cells in GCT of bone were suggested to be identical to osteoclasts, but the characteriz...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2003.01503.x
更新日期:2003-07-01 00:00:00
abstract::Immunodeficient mice are widely used for xenografts of human cells and tissue. The purpose of the present study was to investigate the characteristics of xenograft human tumor models using engraftment of various non-hematopoietic tumors in the NOD/SCID/gamma(c) (null) mouse. For tumor models, human solid tumor tissues...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2008.02271.x
更新日期:2008-09-01 00:00:00
abstract::Homozygous deletion of 9p21, the locus harboring the p16 gene, has been reported as one of the most common genetic alterations in malignant mesotheliomas (MMs). Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens. ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2010.02534.x
更新日期:2010-05-01 00:00:00
abstract::Presented is the first Japanese case of ossifying renal tumor of infancy (ORTI), which is an extremely rare tumor and of which only nine cases have been reported in the literature. The patient was a four-month-old Japanese boy presenting as hematuria. A small nodular tumor (approximately 1 cm in size) protruded into t...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1998.tb03885.x
更新日期:1998-02-01 00:00:00
abstract::Leiomyomatosis peritonealis disseminata (LPD) is a rare clinicopathological entity typically observed in women of reproductive age. We report a case of LPD with malignant change in a man. A 77-year-old man presented with a mass measuring 10 cm in diameter at the terminal ileum and numerous peritoneal small nodules tha...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2003.01452.x
更新日期:2003-03-01 00:00:00
abstract::We have found that the MIB-1 grade, based on tumor differentiation/histological type, necrosis and Ki-67 (MIB-1) score, is a valid and reproducible prognostic system for adult soft-tissue sarcomas. However, there are limited data available on Ki-67 labeling indices (LI) from adult soft-tissue sarcomas for testing the ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2002.01378.x
更新日期:2002-07-01 00:00:00
abstract::Hepatic ultrasonic transient elastography (FibroScan) is a new diagnostic method for the assessment of hepatic fibrosis. There are limited data available on its use as a follow-up tool for patients with chronic hepatitis B. In this study, 134 patients were enrolled. Hepatic fibrosis was evaluated by liver stiffness me...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2010.02515.x
更新日期:2010-04-01 00:00:00
abstract::Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground-glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiologi...
journal_title:Pathology international
pub_type:
doi:10.1111/pin.12945
更新日期:2020-08-01 00:00:00
abstract::A 28-year-old woman complained of irregular menstruation. Abdominal ultrasound and magnetic resonance imaging (MRI) examinations revealed a cystic tumor in the left ovary. A histological examination of the resected ovary revealed that the lesion was a mature cystic teratoma. In this tumor, components such as skin with...
journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1046/j.1440-1827.2001.01288.x
更新日期:2001-11-01 00:00:00
abstract::Alterations in cell surface carbohydrates on human lymphoma cell lines with different spontaneous metastatic potential in the severe combined immunodeficiency (SCID) mouse model were analyzed. A difference in cell surface carbohydrates between high- (HBL-2, HBL-7 and HBL-8) and no- or low-(HBL-4, HBL-6, Daudi and Raji...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1996.tb03577.x
更新日期:1996-12-01 00:00:00
abstract::A case of lymphoid hyperplasia arising in the large intestine of a 54-year-old woman is described. Barium enema X-ray and colonoscopic examination revealed multiple small polyps in the right side of the colon. Pathological findings from forceps biopsy revealed similar features to a mucosa-associated lymphoid tissue (M...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2000.01107.x
更新日期:2000-09-01 00:00:00
abstract::Three cell systems (MINT1/2/3) derived from a melanotic neuroectodermal tumor of infancy (MNTI) arising in the mandible of a 1-month-old newborn boy have been established, and their cytological natures have been characterized. The cells had immunopositivities for pan-keratin, vimentin, neuron-specific enolase, S-100 p...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2005.01833.x
更新日期:2005-06-01 00:00:00
abstract::A case of a 9-year-old boy with fibrocartilaginous mesenchymoma located in the distal femur is presented. Fibrocartilaginous mesenchymoma is a rare tumor. There have been 17 cases reported since 1984. The presenting complaint was pain and local discomfort. Radiological examination showed lytic and sclerotic lesions lo...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2001.01247.x
更新日期:2001-08-01 00:00:00
abstract::A 15 month old female, who had suffered from ventricular tachycardia from the prenatal period, experienced cardiac arrest at home. Once she had recovered, ventricular tachycardia occurred repeatedly. She died 7 months after admission. At autopsy, the heart showed many yellowish white nodules in the endocardium. Histol...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1995.tb03396.x
更新日期:1995-10-01 00:00:00
abstract::Gonadotropin releasing hormone (GnRH) analogs can cause regression of hormone-dependent breast carcinomas via the specific GnRH receptor (GnRH-R). In an attempt to obtain a better understanding of GnRH actions in human breast carcinoma, the expression of GnRH-R was examined immunohistochemically in 58 invasive ductal ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2001.01210.x
更新日期:2001-05-01 00:00:00
abstract::Gastric lipomas are uncommon lesions, usually single and located in the antrum. Common symptoms include upper digestive bleeding, anemia, and intestinal obstruction. Alternatively, they may remain asymptomatic, and detectable only at autopsy. A case of a 72-year-old man, who died of myocardial infarction, was found at...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1997.tb04543.x
更新日期:1997-08-01 00:00:00
abstract::The purpose of the present paper was to examine the level of apoptosis and the relationships among apoptosis, apoptosis-associated proteins, and proliferating potential in lymphoma tissues to clarify the characteristics of apoptosis in diffuse large B-cell lymphomas (DLBCL) of the central nervous system (CNS). The for...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2005.01808.x
更新日期:2005-03-01 00:00:00