Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible.

abstract：:Chronic active Epstein-Barr virus infection (CAEBV) is a syndrome that takes diverse clinical courses and is often associated with lymphoproliferative disorders of T/natural killer (NK)-cell lineage. We describe a patient with CAEBV associated with persistent pharyngeal ulcer, and with subsequent nasal T/NK-cell lymph...

journal_title：Pathology international

authors： Nagata H,Numata T,Konno A,Mikata I,Kurasawa K,Hara S,Nishimura M,Yamamoto K,Shimizu N

更新日期：2001-10-01 00:00:00

abstract：:The juxtaglomerular cell tumor (JGCT) of the kidney is a rare neoplasm which commonly secretes renin. This tumor often occurs in teenagers. This paper documents the 14th adult-onset (over 30-years-old) case with a giant JGCT which measured 9.0 x 8.0 x 7.5 cm. Histologically, this tumor was composed of both vascular an...

journal_title：Pathology international

authors： Kuroda N,Moriki T,Komatsu F,Miyazaki E,Hayashi Y,Naruse K,Nakayama H,Kiyoku H,Hiroi M,Shuin T,Enzan H

更新日期：2000-03-01 00:00:00

abstract：:Solitary fibrous tumor of the pleura (SFTP) is rare. A 73-year-old man, without past history of diabetes mellitus, was admitted to hospital with profound hypoglycemia, loss of consciousness and respiratory failure. CT indicated a huge heterogenous mass lesion (12 x 12 x 17 cm) at the right thoracic cavity with total a...

journal_title：Pathology international

authors： Chang JC,Su KY,Chao SF,Hsu YH,Yang GG,Chang BS

更新日期：2007-12-01 00:00:00

abstract：:Reported herein is a 57-year-old man infected by Sparganum mansoni, a kind of tapeworm, showing a solitary nodule of the middle lobe of the right lung. Because a transbronchial biopsy could not diagnose the nodule, a right middle lobectomy was performed on suspicion of malignant tumor. The lesion was diagnosed as spar...

journal_title：Pathology international

authors： Iwatani K,Kubota I,Hirotsu Y,Wakimoto J,Yoshioka M,Mori T,Ito T,Nomori H

更新日期：2006-11-01 00:00:00

abstract：:We investigated the diagnostic and prognostic value of p53 expression and proliferative activity, as indicated by the Ki-67, in endoscopic biopsy specimens. Specimens were immunologically stained with p53 and MIB-1 (Ki-67), and the MIB-1/Ki-67 labeling index (LI) was calculated. Classification of adenomas was based on...

journal_title：Pathology international

authors： Kubota K,Kakuta Y,Kawamura S,Saito S,Seki H,Kuniyoshi T

更新日期：2003-06-01 00:00:00

abstract：:Angioimmunoblastic T cell lymphoma (AITL) is characterized by the presence of atypical lymphocytes with clear cytoplasm and follicular dendritic cells, arborization of high endothelial blood vessels, and infiltration by inflammatory cells, such as epithelioid histiocytes, eosinophils, immunoblasts, and plasma cells. T...

journal_title：Pathology international

authors： Murakami Y,Shimada K,Kosugi H,Mori N

更新日期：2011-05-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) is a heterodimeric polypeptide growth factor that has pleiotropic roles, including those of mitogen, motogen and morphogen. The HGF receptor is characterized as a c-Met proto-oncogene product (c-Met), which is a heterodimeric tyrosine kinase receptor. Hepatocyte growth factor acts as a m...

journal_title：Pathology international

authors： Motoi T,Ishida T,Kuroda M,Horiuchi H,Oka T,Matsumoto K,Nakamura T,Machinami R

更新日期：1998-10-01 00:00:00

abstract：:Secondary (metastatic) neoplasms to the ovary often cause diagnostic problems, especially those tumors that produce large, symptomatic ovarian tumors that masquerade clinically and pathologically as primary ovarian tumors of surface epithelial type. Most of these tumors arise from organs of the digestive system. Excep...

journal_title：Pathology international

authors： Hart WR

更新日期：2005-05-01 00:00:00

abstract：:Homozygous deletion of 9p21, the locus harboring the p16 gene, has been reported as one of the most common genetic alterations in malignant mesotheliomas (MMs). Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens. ...

journal_title：Pathology international

authors： Takeda M,Kasai T,Enomoto Y,Takano M,Morita K,Kadota E,Nonomura A

更新日期：2010-05-01 00:00:00

abstract：:An unusual tumor in the spinal cord of a 57 year old man is reported. At the age of 42 years, the patient had had a pineal region tumor that subsequently disappeared completely after local radiation therapy only. Eleven and 15 years later, at the ages of 53 and 57 years, respectively, solitary spinal cord tumors were ...

journal_title：Pathology international

authors： Ito T,Takahashi H,Ikuta F,Sato H

更新日期：1994-12-01 00:00:00

abstract：:An 80-year-old woman with a pleomorphic carcinoma (PC) producing hCG was admitted to Nippon Steel Hirohata Hospital because of an abnormal shadow on CT seen during a follow-up examination after surgery for breast cancer. A right upper lobectomy was performed due to rapid growth of the shadow 3 months later. Macroscopi...

journal_title：Pathology international

authors： Hirano H,Yoshida T,Sakamoto T,Yoshimura H,Fukuoka M,Tachibana S,Saito H,Ohkubo E,Nakasho K,Nishigami T

更新日期：2007-10-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are multi-functional cytokines, which belong to the transforming growth factor-β (TGF-β) family. In some cancer tissues, aberrant expression of various BMP signal components has been detected. Here, we describe the divergent roles of BMPs during the progression of cancer. BMPs exhibi...

journal_title：Pathology international

authors： Ehata S,Yokoyama Y,Takahashi K,Miyazono K

更新日期：2013-06-01 00:00:00

abstract：:It has been reported that N-myc downstream regulated gene 1 (NDRG1) is related to the prognosis of non-small cell lung cancer (NSCLC), and associated with c-Myc degradation in NSCLC cell lines. However, the relationship of NDRG1 to prognosis or c-Myc expression in lung adenocarcinoma has not been well clarified. The p...

journal_title：Pathology international

authors： Dai T,Dai Y,Murata Y,Husni RE,Nakano N,Sakashita S,Noguchi M

更新日期：2018-04-01 00:00:00

abstract：:The morphological expression of the immune response of palatine tonsils obtained from patients with pustulosis palmaris et plantaris (PPP) was investigated by morphometry in conjunction with immunohistochemistry. First, to differentiate the histological features of tonsils between PPP and habitual tonsillitis, each ex...

journal_title：Pathology international

authors： Sakai T,Kawaguchi M,Ishizawa S,Kaji T,Kitagawa K,Koizumi F

更新日期：1994-03-01 00:00:00

abstract：:A 15 month old female, who had suffered from ventricular tachycardia from the prenatal period, experienced cardiac arrest at home. Once she had recovered, ventricular tachycardia occurred repeatedly. She died 7 months after admission. At autopsy, the heart showed many yellowish white nodules in the endocardium. Histol...

journal_title：Pathology international

authors： Otani M,Hoshida H,Saji T,Matsuo N,Kawamura S

更新日期：1995-10-01 00:00:00

abstract：:The purpose of the present study was to clarify the difference of expression of two stem cell markers, nestin and c-kit, among various pancreatic epithelial tumors and evaluate their utility. Immunohistochemistry was done for 99 surgically resected pancreatic tumor specimens, including 20 ductal adenocarcinoma (DAC), ...

journal_title：Pathology international

authors： Ohike N,Sato M,Hisayuki T,Imataka H,Sato S,Wada Y,Saito K,Takahashi M,Tajiri T,Kunimura T,Morohoshi T

更新日期：2007-09-01 00:00:00

abstract：:Multiple injections with a mouse monoclonal anti-rat Thy-1 antibody (five times, at weekly intervals) induced marked glomerular sclerotic lesions which are characterized by adhesion of glomerular capillaries to Bowman's capsule and persistent proteinuria in rats. Abnormal production of type I collagen and increased ac...

journal_title：Pathology international

authors： Yagi M,Yamamoto T,Kato S,Nagano N,Kihara I

更新日期：1998-07-01 00:00:00

abstract：:Calcifying fibrous tumor (CFT) is an uncommon lesion of uncertain cause and pathogenesis that has a unique histological appearance. These lesions are described mainly in the subcutaneous or deep soft tissues, followed by subserosal locations. Intrinsic visceral CFT is extremely rare. Herein is described a rare case of...

journal_title：Pathology international

authors： Elpek GO,Küpesiz GY,Ogüs M

更新日期：2006-04-01 00:00:00

abstract：:We compared the c-erbB-2 protein overexpression status detected by the HercepTestTM (DAKO A/S, Grostrup, Denmark) with another conventional immunohistochemistry system using an anti-c-erbB-2 rabbit polyclonal antibody (Nichirei Co., Tokyo, Japan) and with the c-erbB-2 gene amplification status detected by Southern blo...

journal_title：Pathology international

authors： Tsuda H,Tani Y,Hasegawa T,Fukutomi T

更新日期：2001-01-01 00:00:00

abstract：:Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare kidney neoplasm that almost exclusively occurs in perimenopausal women, and long-term estrogen replacement is relevant to its pathogenesis. Herein is described an atypical case of MESTK uncovered in a 12-year-old premenarcheal girl without a history of...

journal_title：Pathology international

authors： Hara N,Kawaguchi M,Murayama S,Maruyama R,Tanikawa T,Takahashi K

更新日期：2005-10-01 00:00:00

abstract：:We report a very rare case of combined thymic carcinomas: undifferentiated thymic carcinoma coexisting with type AB thymoma. The precise mechanism underlying the coexistence of these tumors remains unknown. Therefore, we used clonality analysis to ascertain whether the two tumors were clonally related. A 63-year-old w...

journal_title：Pathology international

authors： Karino F,Yokose T,Matsukuma S,Miyagi Y,Murakami S,Ito H,Nakayama H,Yamada K

更新日期：2016-07-01 00:00:00

abstract：:Under the condition of obvious iron-overload, there is a zonal hemosiderin (iron) deposition in hepatic lobules. The deposition is heaviest in the periportal (zone 1) and lightest in the perivenous (zone 3) hepatocytes. However, the mechanism for this pattern of iron deposition is obscure. Hepatic tissues from control...

journal_title：Pathology international

authors： Lu JP,Hayashi K

更新日期：1995-03-01 00:00:00

abstract：:The present study attempted to clarify the significance of aberrant expression of beta-catenin protein and mutation of exon 3 of the beta-catenin gene in renal and urothelial carcinogenesis. beta-Catenin expression was examined immunohistochemically and mutation of the beta-catenin gene was analyzed by polymerase chai...

journal_title：Pathology international

authors： Zhu X,Kanai Y,Saito A,Kondo Y,Hirohashi S

更新日期：2000-12-01 00:00:00

abstract：:Although a seborrheic keratosis is not rare on the skin of the trunk, extremities, head and neck of an elderly person, it is uncommon to originate in the external ear canal. Even rarer, an irritated subtype may arise in this location. We report the case of a 63-year-old man with an irritated seborrheic keratosis arisi...

journal_title：Pathology international

authors： Konishi E,Nakashima Y,Manabe T,Mazaki T,Wada Y

更新日期：2003-09-01 00:00:00

abstract：:An unusual case of cystic renal cell carcinoma in a 70-year-old Japanese male is reported. He had had a simple renal cyst removed 1 year ago. On presentation the right kidney was surrounded by multiple translucent cysts, which varied in size from 1 to 50 mm. The cyst walls were lined by single-layered cuboidal epithel...

journal_title：Pathology international

authors： Shishikura Y,Furusato M,Aizawa S

更新日期：1998-08-01 00:00:00

abstract：:Nestin is an intermediate filament that was first identified in neural progenitor cells. It is expressed in various cell types in the nervous system as well as in other systems. In the present study, we investigated nestin expression in non-neoplastic salivary gland tissue and in salivary gland tumors. In non-neoplast...

journal_title：Pathology international

authors： Yanai H,Sato Y,Nagatsuka H,Yoshino T

更新日期：2013-10-01 00:00:00

abstract：:The p73 gene is a member of the p53 gene family and the structure and functions of p73 protein are similar to those of p53. However, these two proteins have different roles. In the present study, p73 protein was found immunohistochemically to be distributed in the basal cells of the epidermis, columnar basal cells in ...

journal_title：Pathology international

authors： Kamiya M,Takeuchi Y,Katho M,Yokoo H,Sasaki A,Nakazato Y

更新日期：2004-12-01 00:00:00

abstract：:We report a case of cutaneous squamous cell carcinoma (CSCC), initially coexisting with invasive extramammary Paget's disease (EMPD), in the scrotum of an 84-year-old man. The patient initially had a rash and pruritus before presenting with a pedunculated scrotal mass surrounded by widespread erythema. He underwent to...

journal_title：Pathology international

authors： Kitano A,Izumi M,Tamura K,Tonegawa M,Etou T,Kishida Y

更新日期：2019-10-01 00:00:00

abstract：:Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec...

journal_title：Pathology international

authors： Sadahira Y,Moriya T,Shirabe T,Matsuno T,Manabe T

更新日期：1996-08-01 00:00:00

abstract：:Phyllodes tumor is a very rare neoplasm which accounts for 2.5% of all fibroepithelial lesions of the breast. The mesenchymal component of a malignant phyllodes tumor frequently contains heterologous components. We report a case of malignant phyllodes tumor. The patient was a 40-year-old woman with a lump on the left ...

journal_title：Pathology international

authors： Kuroda N,Sugimoto T,Ueda S,Takahashi T,Moriki T,Sonobe H,Miyazaki E,Hayashi Y,Toi M,Hiroi M,Enzan H

更新日期：2001-04-01 00:00:00