Abstract:
:One of the striking microscopic appearances of breast carcinoma is malignant transformation of the epithelium of an entire lobule, although the lobular architecture is still preserved. We termed this pathological feature 'lobular involvement'. An investigation was carried out to determine whether lobular involvement would be a useful prognostic indicator for invasive ductal carcinoma. One hundred and fifty cases of invasive ductal carcinoma were included in this study. The lobular involvement, as well as the conventional prognostic factors, was evaluated to find out the correlation with the overall and relapse-free survivals by univariate and multivariate analyses. The lobular involvement was identified in 31 of 150 patients (20.6%). Of the patients with lobular involvement, two had experienced recurrence (6.5%) and one had died (3.2%). The lobular involvement and lymph node metastases were significantly and independently correlated with the overall and relapse-free survivals. The presence of lobular involvement was statistically correlated with the favorable outcome. Lobular involvement can be assumed as a new prognostic indicator for invasive ductal carcinoma.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Ishige H,Kondo Y,Yagata H,Onoki J,Suzuki M,Oshida M,Nagashima T,Hashimoto H,Nakajima Ndoi
10.1046/j.1440-1827.1999.00899.xsubject
Has Abstractpub_date
1999-06-01 00:00:00pages
485-90issue
6eissn
1320-5463issn
1440-1827pii
pin899journal_volume
49pub_type
杂志文章abstract::Methotrexate (MTX) is currently used as first-line anchor drug for rheumatoid arthritis (RA). Therefore, the number of MTX-associated lymphoproliferative disorders, including Epstein-Barr virus-positive mucocutaneous ulcer (EBVMCU), has increased. Some aspects of MTX-associated EBVMCU (MTX-EBVMCU), particularly clinic...
journal_title:Pathology international
pub_type: 杂志文章
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journal_title:Pathology international
pub_type: 杂志文章
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journal_title:Pathology international
pub_type: 杂志文章
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abstract::The aim of the present study is to clarify the clinicopathological correlation of childhood IgA glomerulonephritis (GN) presenting diffuse endocapillary proliferation. Twenty-seven patients were used in the present study. The 27 patients were divided into three groups (mild, moderate and severe) according to the perce...
journal_title:Pathology international
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journal_title:Pathology international
pub_type: 杂志文章
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journal_title:Pathology international
pub_type: 杂志文章
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journal_title:Pathology international
pub_type: 杂志文章
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.2007.02206.x
更新日期:2008-03-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/pin.12048
更新日期:2013-04-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:2004-05-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.1999.00877.x
更新日期:1999-05-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章,评审
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更新日期:2002-04-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:2009-02-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1994.tb02591.x
更新日期:1994-03-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1997.tb03720.x
更新日期:1997-12-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.1999.00865.x
更新日期:1999-04-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章,评审
doi:10.1111/j.1440-1827.1995.tb03386.x
更新日期:1995-10-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:1997-10-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:2013-10-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1046/j.1440-1827.2001.01247.x
更新日期:2001-08-01 00:00:00
abstract::An unusual tumor in the spinal cord of a 57 year old man is reported. At the age of 42 years, the patient had had a pineal region tumor that subsequently disappeared completely after local radiation therapy only. Eleven and 15 years later, at the ages of 53 and 57 years, respectively, solitary spinal cord tumors were ...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1994.tb01685.x
更新日期:1994-12-01 00:00:00
abstract::Reported herein is a 57-year-old man infected by Sparganum mansoni, a kind of tapeworm, showing a solitary nodule of the middle lobe of the right lung. Because a transbronchial biopsy could not diagnose the nodule, a right middle lobectomy was performed on suspicion of malignant tumor. The lesion was diagnosed as spar...
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pub_type: 杂志文章
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更新日期:2006-11-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
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更新日期:2002-09-01 00:00:00
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journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1994.tb02589.x
更新日期:1994-01-01 00:00:00
abstract::In order to clarify the relationship between cyclin D1 and D2 (CD1/CD2) overexpression and progression, 191 gastric cancer cases (81 early and 110 advanced cancers) were investigated using the 5D4 monoclonal antibody for both CD1/CD2 in immunohistochemistry. 5D4 immunoreactivity was noted in 68 (35.6%) cases, staining...
journal_title:Pathology international
pub_type: 杂志文章
doi:10.1111/j.1440-1827.1998.tb03972.x
更新日期:1998-09-01 00:00:00
abstract::The value of fluorescence in situ hybridization (FISH) as an aid to deciding the prognosis for lung carcinoma patients, comparing quantitatively the signal from the p53 gene (17p13.1) on chromosome 17, was studied. A dual-labeling technique was used, using probes for the centromeric region of chromosome 17 and for the...
journal_title:Pathology international
pub_type: 杂志文章
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更新日期:2004-06-01 00:00:00