Immunohistochemistry of gliosarcoma with liposarcomatous differentiation.

abstract：:Autosomal recessive polycystic kidney disease (ARPKD) is caused by genetic mutations of the gene encoding fibrocystin, and is characterized by the collecting duct cysts and congenital hepatic fibrosis. We report an autopsy-proven case of ARPKD in a 77-year-old male who presented with rapidly progressive renal and live...

journal_title：Pathology international

authors： Taneda S,Honda K,Aoki A,Nitta K,Tamura T,Yoshioka Y,Oda H

更新日期：2012-12-01 00:00:00

abstract：:A case of squamous cell carcinoma arising within an acquired seminal vesicular cyst is described. A 61-year-old man was hospitalized because of hemospermia and dysuria. Under the diagnosis of a left seminal vesicular cyst, surgical resection was performed. Pathological examination revealed squamous cell carcinoma with...

journal_title：Pathology international

authors： Yanagisawa N,Saegusa M,Yoshida T,Okayasu I

更新日期：2002-03-01 00:00:00

abstract：:We report a case of a 57-year-old man who developed a fibrosclerosing lesion in the submandibular gland and idiopathic retroperitoneal fibrosis (IRF) involving the unilateral periureteral region within a year. Both lesions were resected surgically because of the suspicion of neoplasm. Pathologic examination revealed s...

journal_title：Pathology international

authors： Sekine S,Nagata M,Watanabe T

更新日期：1999-07-01 00:00:00

abstract：:A case of small cell carcinoma of the gall-bladder is described. Immunohistochemically, the tumor cells were positive for chromogranin A, synaptophysin and neuronspecific enolase, which suggests that they derived from neuroendocrine cells. The overlying and surrounding epithelium of the tumor showed intestinal metapla...

journal_title：Pathology international

authors： Kuwabara H,Uda H

更新日期：1998-04-01 00:00:00

abstract：:An association between autoimmune pancreatitis (AIP) and inflammatory abdominal aortic aneurysm (AAA) has never been reported. Reported herein is a case of IgG4-related inflammatory AAA accompanying metachronous AIP. A 77-year-old man presented with malaise and intermittent lower abdominal pain. Radiological examinati...

journal_title：Pathology international

authors： Ito H,Kaizaki Y,Noda Y,Fujii S,Yamamoto S

更新日期：2008-07-01 00:00:00

abstract：:The purpose of the present paper was to examine the level of apoptosis and the relationships among apoptosis, apoptosis-associated proteins, and proliferating potential in lymphoma tissues to clarify the characteristics of apoptosis in diffuse large B-cell lymphomas (DLBCL) of the central nervous system (CNS). The for...

journal_title：Pathology international

authors： Arai M,Sasaki A,Saito N,Nakazato Y

更新日期：2005-03-01 00:00:00

abstract：:beta-Catenin has multiple functions both in intercellular adhesion and in signal transduction. As a signaling molecule, mutations in exon 3 of the beta-catenin gene stabilize this protein in the cytoplasm. Subsequently, accumulated beta-catenin protein translocates to nuclei with T-cell factor-4, and upregulates trans...

journal_title：Pathology international

authors： Miyake N,Maeta H,Horie S,Kitamura Y,Nanba E,Kobayashi K,Terada T

更新日期：2001-09-01 00:00:00

abstract：:We have reported that the function of histamine and its receptors (HRs) has a close relationship with the development of nonalcoholic fatty liver disease (NAFLD). However, much less is known regarding its pathogenic and molecular mechanism(s), including the early stage of hepatic and intestinal function for lipid and ...

journal_title：Pathology international

authors： Yamada S,Guo X,Wang KY,Tanimoto A,Sasaguri Y

更新日期：2016-07-01 00:00:00

abstract：:High-grade transformation (HGT)/dedifferentiation is an unusual phenomenon in salivary gland carcinomas. Here we report a case of adenoid cystic carcinoma (ACC) with HGT/dedifferentiation to myoepithelial carcinoma, occurring in the epipharynx of a 42-year-old woman. The surgically resected tumor was a pedunculated ma...

journal_title：Pathology international

authors： Tando S,Nagao T,Kayano K,Fushiki S,Itoh K

更新日期：2018-02-01 00:00:00

abstract：:BRN2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. We investigated the importance of BRN2 in the expression of the lineage-specific transcription factors (achaete-scute homolog-like 1 (ASCL1) and NeuroD1 (ND1)) and neural/neuroendocrine marker mo...

journal_title：Pathology international

authors： Ishii J,Sato H,Sakaeda M,Shishido-Hara Y,Hiramatsu C,Kamma H,Shimoyamada H,Fujiwara M,Endo T,Aoki I,Yazawa T

更新日期：2013-03-01 00:00:00

abstract：:Adenomyoma of the small intestine is a rare tumor-like lesion composed of exocrine-type ducts and hypertrophic smooth muscle. We describe two cases of adenomyoma of the small intestine. One was an ileal adenomyoma that presented with intussusception occurring in a 7-month-old boy. The other was a jejunal adenomyoma fo...

journal_title：Pathology international

authors： Park HS,Lee SO,Lee JM,Kang MJ,Lee DG,Chung MJ

更新日期：2003-02-01 00:00:00

abstract：:In order to confirm the role of 14-3-3 sigma (sigma) as a tumor suppressor in breast carcinogenesis, we have studied the expression of 14-3-3sigma immunohistochemically in usual ductal hyperplasia (UDH), ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) breast lesions. Immunostaining for estrogen rec...

journal_title：Pathology international

authors： Simooka H,Oyama T,Sano T,Horiguchi J,Nakajima T

更新日期：2004-08-01 00:00:00

abstract：:A multi-institutional study 'Pathobiological Determinants of Atherosclerosis in Youth' (PDAY) was initiated to document the natural history of atherosclerosis, its relationship to risk factors, and pathobiology of lesion development in young subjects. Pathology laboratories in nine centers collected arteries and tissu...

journal_title：Pathology international

authors： Strong JP,Malcom GT,Oalmann MC

更新日期：1995-06-01 00:00:00

abstract：:The aim of the present study was to clarify protein profiling in small cell lung carcinoma (SCLC) and pulmonary large cell neuroendocrine carcinoma (LCNEC). The proteomic approach was used, and involved cell lysate from two cell lines (N231 derived from SCLC and LCN1 derived from LCNEC), with 2-D gel electrophoresis (...

journal_title：Pathology international

authors： Nagashio R,Sato Y,Matsumoto T,Kageyama T,Satoh Y,Ryuge S,Masuda N,Jiang SX,Okayasu I

更新日期：2010-02-01 00:00:00

abstract：:Many new members of the S-100 genes are known to be associated with cell differentiation, malignant transformation, and cell cycle. Of the S-100 genes examined in the present study, calcyclin, calpactin I light chain and calvasculin were expressed in most human epithelial tumor cells, and their expression levels diffe...

journal_title：Pathology international

authors： Matsumoto T,Murao S,Kito K,Kihana T,Matsuura S,Ueda N

更新日期：1997-06-01 00:00:00

abstract：:So-called 'hybrid' lesion of ameloblastoma, which is composed of desmoplastic ameloblastoma and conventional follicular/plexiform ameloblastoma, is an unusual variant of ameloblastoma and only eight cases of 'hybrid' lesion have been published in the English literature. To enhance knowledge of this interesting tumor, ...

journal_title：Pathology international

authors： Takata T,Miyauchi M,Ogawa I,Zhao M,Kudo Y,Sato S,Takekoshi T,Nikai H,Tanimoto K

更新日期：1999-11-01 00:00:00

abstract：:Two cases of carcinosarcoma of the esophagus are reported. Both were polypoid tumors occurring in the middle of the intrathoracic esophagus. The tumors were predominantly composed of spindle-shaped sarcoma cells with some squamous cell carcinomas (SCC). One tumor showed many bizarre giant cells with filamentous materi...

journal_title：Pathology international

authors： Taniyama K,Sasaki N,Mukai T,Uemura N,Miyoshi N,Nakai H,Nakayama H,Tahara E

更新日期：1995-04-01 00:00:00

abstract：:A case of primary esophageal adenocarcinoma in a 64-year-old man is reported. An ulcerating tumor was located in the middle intrathoracic esophagus. Histopathological examination revealed a moderately differentiated adenocarcinoma, which had invaded down to the adventitia. The cancerous tubuli were lined by flattened ...

journal_title：Pathology international

authors： Endoh Y,Miyawaki M,Tamura G,Watanabe H,Motoyama T

更新日期：1999-02-01 00:00:00

abstract：:The etiological role of human papillomavirus (HPV) in esophageal carcinoma (EC) in relation to p53, mdm2, p21(waf), c-erbB2 and the overall survival (OS) rate was investigated. Tumor and normal tissues from 50 EC were evaluated by polymerase chain reaction and InnoLiPA for HPV. Single strand conformation polymorphism/...

journal_title：Pathology international

authors： Bahnassy AA,Zekri AR,Abdallah S,El-Shehaby AM,Sherif GM

更新日期：2005-02-01 00:00:00

abstract：:Thymidine phosphorylase (dThdPase)/platelet-derived endothelial cell growth factor, is expressed at higher levels in tumor tissues compared to the adjacent normal tissues in a variety of human carcinomas. The higher expression is associated with an increase of intratumoral microvessel density (IMVD) and an unfavorable...

journal_title：Pathology international

authors： Okamoto E,Osaki M,Kase S,Adachi H,Kaibara N,Ito H

更新日期：2001-03-01 00:00:00

abstract：:Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground-glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiologi...

journal_title：Pathology international

authors： Hashimoto H,Matsumoto J,Murakami M,Hiyama N,Yamaguchi H,Kusakabe M,Horiuchi H,Morikawa T

更新日期：2020-08-01 00:00:00

abstract：:Two cases of endometrial low-grade stromal sarcoma with ovarian sex cord-like differentiation occurring in a 39-year-old woman and a 42-year-old woman are presented. Both tumors, which were intramyometrial and measured 7.5 cm and 7.0 cm in greatest diameter, respectively, showed a multinodular, ill-demarcated, and yel...

journal_title：Pathology international

authors： Fukunaga M,Miyazawa Y,Ushigome S

更新日期：1997-06-01 00:00:00

abstract：:A 35-year-old Japanese man who had experienced hoarseness for 10 years presented with a vocal cord lesion. A gross examination revealed a left vocal cord polyp occupying two-thirds of the vocal space. The endoscopically resected lesion contained scattered atypical fibroblastic, stellate, or ganglion-like cells with mu...

journal_title：Pathology international

authors： Yorita K,Togashi Y,Nakagawa H,Miyazaki K,Sakata S,Baba S,Takeuchi K,Hayashi Y,Murakami I,Kuroda N,Oda Y,Kohashi K,Yamada Y,Kiyozawa D,Michal M,Michal M

更新日期：2019-06-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy is an unusual malignancy-related respiratory complication characterized by multiple microthrombi and intimal myofibroblast proliferation. Its clinical manifestation is subacute respiratory failure with pulmonary hypertension. Herein is reported a case of pulmonary tumor throm...

journal_title：Pathology international

authors： Sakashita N,Yokose C,Fujii K,Matsumoto M,Ohnishi K,Takeya M

更新日期：2007-06-01 00:00:00

abstract：:Ovarian non-gestational choriocarcinomas co-existing with adenocarcinoma are extremely rare and have been reported as epithelial ovarian carcinomas of a "non-germ cell origin" with "choriocarcinomatous differentiation". Although the cellular origin of non-gestational choriocarcinoma may be post-meiotic ovarian germ ce...

journal_title：Pathology international

authors： Koyanagi T,Fujiwara H,Usui H,Ariga H,Machida S,Takei Y,Saga Y,Shozu M,Fukushima N,Niki T,Matsubara S,Suzuki M

更新日期：2016-09-01 00:00:00

abstract：:Reported herein is a case of medulloblastoma with myogenic differentiation in a 3-year-old girl who died 1 year after appearance of clinical signs. Magnetic resonance imaging indicated a mass lesion in the cerebellar vermis. She underwent total resection of the tumor, followed by chemotherapy and radiotherapy in the b...

journal_title：Pathology international

authors： Kido M,Ueno M,Onodera M,Matsumoto K,Imai T,Haba R,Tamiya T,Huang CL,Sakamoto H

更新日期：2009-04-01 00:00:00

abstract：:We describe a case of minute pancreatic ductal adenocarcinoma featuring stenosis of the main pancreatic duct (MPD) and associated with histological findings of periductal elastosis and fibroblast proliferation. A 53-year-old Japanese man with preoperative radiological evidence of MPD stricture and dilation of the dist...

journal_title：Pathology international

authors： Yachida S,Fukushima N,Nakanishi K,Shimada K,Kosuge T,Sakamoto M

更新日期：2002-09-01 00:00:00

abstract：:Collagenous fibroma (desmoplastic fibroblastoma) is a distinctive benign fibrous soft tissue tumor that typically occurs in the subcutaneous tissue or skeletal muscle in adults. We describe a case of collagenous fibroma in a 7-year-old boy who presented with a 1-cm solitary, firm nodule on the volar aspect of the meta...

journal_title：Pathology international

authors： Nishio J,Iwasaki H,Nishijima T,Kikuchi M

更新日期：2002-04-01 00:00:00

abstract：:A report of a 65-year-old male with a tumor arising from synovial tissue of the radio-ulnar joint. On magnetic resonance imaging, the tumor was demonstrated as a heterogeneous and lobulated mass with a low signal intensity both in T1- and T2-weighted images. Histological findings of the tumor were identical to those o...

journal_title：Pathology international

authors： Misawa A,Okada K,Hirano Y,Sageshima M

更新日期：1999-12-01 00:00:00

abstract：:Resistance to retroviral infection is often regulated by multiple genes that control different aspects of the host-virus interaction. Genetically distinct inbred strains of mice differ in their susceptibility to retrovirus and have allowed the identification of several host-resistant loci that regulate the host defens...

journal_title：Pathology international

authors： Kitagawa M,Aizawa S,Ikeda H,Hirokawa K

更新日期：1996-10-01 00:00:00