Minute pancreatic adenocarcinoma presenting with stenosis of the main pancreatic duct.

abstract：:A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobect...

journal_title：Pathology international

authors： Zhang Z,Nonaka H,Nagayama T,Hatori T,Ihara F,Zhang L,Akima M,Shiba T

更新日期：2001-12-01 00:00:00

abstract：:Although mucinous carcinoma (MC) of the breast is considered to originate from ductal carcinoma, it is not known whether mucinous growth begins in the intraductal carcinoma or later in the invasive carcinoma. In this study, 33 MC (16 pure without any ductal components, 10 mixed Type I with an intraductal component, se...

journal_title：Pathology international

authors： Kato N,Endo Y,Tamura G,Katayama Y,Motoyama T

更新日期：1999-11-01 00:00:00

abstract：:The overexpression of p53 protein and the Ki67 proliferative index was evaluated in 96 hepatocellular carcinomas (HCC), 67 in cirrhotic livers and 29 in non-cirrhotic ones, and in 13 non-carcinomatous lesions, all surgically resected from Italian patients. Overexpression of p53 was detected only in carcinomatous lesio...

journal_title：Pathology international

authors： D'Errico A,Grigioni WF,Fiorentino M,Baccarini P,Grazi GL,Mancini AM

更新日期：1994-09-01 00:00:00

abstract：:A small proportion of patients with chronic lymphocytic leukemia (CLL) may progress to large cell lymphoma, or Richter syndrome (RS). The large cells of RS may arise through transformation of the original CLL clone (clonally related) or represent a new neoplasm (clonally unrelated), which might be Epstein-Barr virus (...

journal_title：Pathology international

authors： Chen YA,Wang RC,Yang Y,Chuang SS

更新日期：2016-07-01 00:00:00

abstract：:We report a case of cutaneous squamous cell carcinoma (CSCC), initially coexisting with invasive extramammary Paget's disease (EMPD), in the scrotum of an 84-year-old man. The patient initially had a rash and pruritus before presenting with a pedunculated scrotal mass surrounded by widespread erythema. He underwent to...

journal_title：Pathology international

authors： Kitano A,Izumi M,Tamura K,Tonegawa M,Etou T,Kishida Y

更新日期：2019-10-01 00:00:00

abstract：:Giant cell tumor (GCT) of bone is a primary osteolytic tumor that is characterized by the formation of osteoclast-like giant cells. In addition to GCT of bone, extraskeletal GCT are known to be formed in several soft tissues. Giant cells in GCT of bone were suggested to be identical to osteoclasts, but the characteriz...

journal_title：Pathology international

authors： Ikeda T,Seki S,Maki M,Noguchi N,Kawamura T,Arii S,Igari T,Koike M,Hirokawa K

更新日期：2003-07-01 00:00:00

abstract：:A cytometrical image analyzing method for nuclear protein was established using WinROOF, a commercially available, inexpensive software, to determine the status of both estrogen and progesterone receptors. Immunohistochemical evaluation of estrogen receptors (ER) and progesterone receptors (PR) was performed with the ...

journal_title：Pathology international

authors： Hatanaka Y,Hashizume K,Nitta K,Kato T,Itoh I,Tani Y

更新日期：2003-10-01 00:00:00

abstract：:In order to confirm the role of 14-3-3 sigma (sigma) as a tumor suppressor in breast carcinogenesis, we have studied the expression of 14-3-3sigma immunohistochemically in usual ductal hyperplasia (UDH), ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) breast lesions. Immunostaining for estrogen rec...

journal_title：Pathology international

authors： Simooka H,Oyama T,Sano T,Horiguchi J,Nakajima T

更新日期：2004-08-01 00:00:00

abstract：:We compared the c-erbB-2 protein overexpression status detected by the HercepTestTM (DAKO A/S, Grostrup, Denmark) with another conventional immunohistochemistry system using an anti-c-erbB-2 rabbit polyclonal antibody (Nichirei Co., Tokyo, Japan) and with the c-erbB-2 gene amplification status detected by Southern blo...

journal_title：Pathology international

authors： Tsuda H,Tani Y,Hasegawa T,Fukutomi T

更新日期：2001-01-01 00:00:00

abstract：:A case is reported of intra-abdominal desmoplastic small cell tumor (IDSCT) with biphasic histologic features in a patient with proximal spinal muscular atrophy. The tumor was composed of small epithelial cell nests with spindle cell sarcomatous areas. Both areas were surrounded by a desmoplastic stroma. Immunohistoch...

journal_title：Pathology international

authors： Motoyama T,Maejima T,Aizawa K,Fukuda T,Watanabe H

更新日期：1996-01-01 00:00:00

abstract：:Infantile myofibromatosis (IM) is a rare disorder present at birth or in early infancy with a biphasic histological pattern. We present a neonatal-onset case of generalized IM with visceral (central nervous system, heart, lungs, liver, spleen, small intestine, kidneys and bones) and placental involvement, showing a mo...

journal_title：Pathology international

authors： Iwafuchi H,Tsuzuki T,Ito R,Miyake H,Okita H,Hamazaki M

更新日期：2015-08-01 00:00:00

abstract：:An unusual case of cystic renal cell carcinoma in a 70-year-old Japanese male is reported. He had had a simple renal cyst removed 1 year ago. On presentation the right kidney was surrounded by multiple translucent cysts, which varied in size from 1 to 50 mm. The cyst walls were lined by single-layered cuboidal epithel...

journal_title：Pathology international

authors： Shishikura Y,Furusato M,Aizawa S

更新日期：1998-08-01 00:00:00

abstract：:Malignant lymphoma arising in the stomach of a 23-year-old Japanese man with systemic sarcoidosis is presented. The patient was followed because of systemic sarcoidosis involving the lungs, eyes, and lymph nodes. Biopsy specimens from the stomach were repeated because of recurrent epigastralgia and multiple ulceration...

journal_title：Pathology international

authors： Fukuda T,Sato K,Tachikawa S,Ohnuki K,Ohtani H,Suzuki T

更新日期：1997-12-01 00:00:00

abstract：:Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec...

journal_title：Pathology international

authors： Sadahira Y,Moriya T,Shirabe T,Matsuno T,Manabe T

更新日期：1996-08-01 00:00:00

abstract：:An extremely rare case of malignant mesothelioma of the pericardium is reported. The tumor appeared to be the biphasic type of diffuse malignant mesothelioma which present many small to fine lipid droplets in the cytoplasm, particularly that of the epithelial cell, and a positive immunohistochemical reaction with anti...

journal_title：Pathology international

authors： Ohmori T,Arita N,Okada K,Kondo M,Tabei R

更新日期：1995-08-01 00:00:00

abstract：:Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare genetic disorder characterized by cutaneous and uterine leiomyomatosis with RCC. This disorder is caused by a germline mutation in the fumarate hydratase (FH) gene, which encodes an important enzyme of the tricarboxylic acid (TCA) cycle. This mutation d...

journal_title：Pathology international

authors： Matsumoto K,Udaka N,Hasumi H,Nakaigawa N,Nagashima Y,Tanaka R,Kato I,Yao M,Furuya M

更新日期：2018-05-24 00:00:00

abstract：:A rare case of a macrofollicular variant of papillary thyroid carcinoma occurring in an 18-year-old male is described. The extirpated tumor, 5.5 x 5.5 x 3.5 cm in size, was well demarcated and multinodular, and histopathologically showed a predominantly macrofollicular structure reminiscent of adenomatous goiter or ma...

journal_title：Pathology international

authors： Nakamura T,Moriyama S,Nariya S,Sano K,Shirota H,Kato R

更新日期：1998-06-01 00:00:00

abstract：:This report presents a case of neural fibrolipoma arising from the superficial peroneal nerve in the ankle. A 28-year-old woman was referred with a soft tissue mass in the anterior aspect of the right ankle, which had been gradually enlarging for the past 10 years. Magnetic resonance imaging showed a mass lesion, meas...

journal_title：Pathology international

authors： Akisue T,Matsumoto K,Yamamoto T,Kizaki T,Fujita I,Yoshiya S,Kurosaka M

更新日期：2002-11-01 00:00:00

abstract：:Nodular fasciitis (NF) is a self-limiting benign disease that is characterized by rapid proliferation of fibroblastic and myofibroblastic cells. The characteristic gene fusion containing the USP6 gene is a genetic hallmark of NF and MYH9-USP6 is the most frequent fusion, suggesting that NF is not a reactive condition ...

journal_title：Pathology international

authors： Teramura Y,Yamazaki Y,Tanaka M,Sugiura Y,Takazawa Y,Takeuchi K,Nakayama T,Kaneko T,Musha Y,Funauchi Y,Ae K,Matsumoto S,Nakamura T

更新日期：2019-12-01 00:00:00

abstract：:Recent studies imply that cancer cells possess the ability to reversibly change their properties between a drug sensitive state and a drug resistant state accompanied by epigenetic changes. This evidence indicates that better understanding of cancer epigenetics is important for efficient cancer therapies. Nevertheless...

journal_title：Pathology international

authors： Matsuda Y,Semi K,Yamada Y

更新日期：2014-07-01 00:00:00

abstract：:Schwarz and Benditt found clustering of replicating cells in aortic endothelium in 1976 and discussed how homeostasis of the arterial wall is maintained through this nonrandom distribution of replicating cells. However, it is still unclear how cells of vascular walls turnover. In order to address this issue, we evalua...

journal_title：Pathology international

authors： Takahashi M,Masuda H,Yoshida M,Ito Y,Nanjo H,Sugiyama T,Maeda D,Goto A

更新日期：2015-11-01 00:00:00

abstract：:A 54-year-old Japanese woman was referred with a gallbladder tumor. Based on the results of the computed tomography scan, endoscopic retrograde cholangiopancreatography, and magnetic resonance cholangiopancreatography, a mucin-producing neoplasm of the gallbladder associated with pancreaticobiliary maljunction was dia...

journal_title：Pathology international

authors： Meguro Y,Fukushima N,Koizumi M,Kasahara N,Hydo M,Morishima K,Sata N,Lefor AT,Yasuda Y

更新日期：2014-09-01 00:00:00

abstract：:CpG island methylator phenotype (CIMP) is a recently described subset of colorectal cancers (CRC) with widespread methylation of multiple promoter CpG islands. But the prognostic implication of CIMP in CRC has not been clarified. Thus, the aim of the present study was to differentiate the unique characteristics of CIM...

journal_title：Pathology international

authors： Lee S,Cho NY,Choi M,Yoo EJ,Kim JH,Kang GH

更新日期：2008-02-01 00:00:00

abstract：:Many reports have suggested a strong correlation between certain lectin-binding patterns and biological behavior in various tumors. To clarify a relationship between lectin-binding reactivity and survival of patients with diffuse large B-cell lymphoma (B-DLCL), 57 cases with B-DLCL were analyzed by lectin histochemist...

journal_title：Pathology international

authors： Suzuki O,Nozawa Y,Kawaguchi T,Abe M

更新日期：1999-10-01 00:00:00

abstract：:In pulmonary fibrosis, it is known that fibrotic changes develop in the intra-alveolar spaces and that intra-alveolar fibrosis can be classified into three patterns, namely intra-alveolar buds, mural incorporation and obliterative changes. In order to clarify the evolution of intra-alveolar fibrosis, immunohistochemic...

journal_title：Pathology international

authors： Usuki J,Fukuda Y

更新日期：1995-08-01 00:00:00

abstract：:A 56-year-old male treated for a gastric yolk sac tumor with an adenocarcinomatous component is described. A mixed area of reticular and glandular neoplastic components was morphologically identified in this tumor. Immunohistochemically, the yolk sac tumor expressed alpha-fetoprotein (AFP), placental alkaline phosphat...

journal_title：Pathology international

authors： Suzuki T,Kimura N,Shizawa S,Yabuki N,Yamaki T,Sasano H,Nagura H

更新日期：1999-06-01 00:00:00

abstract：:The chemokine receptor CXCR4 belongs to the large superfamily of G protein-coupled receptors and has been identified to play a crucial role in a number of biological processes, including the trafficking and homeostasis of immune cells such as T lymphocytes. CXCR4 has also been found to be a prognostic marker in variou...

journal_title：Pathology international

authors： Furusato B,Mohamed A,Uhlén M,Rhim JS

更新日期：2010-07-01 00:00:00

abstract：:Under the condition of obvious iron-overload, there is a zonal hemosiderin (iron) deposition in hepatic lobules. The deposition is heaviest in the periportal (zone 1) and lightest in the perivenous (zone 3) hepatocytes. However, the mechanism for this pattern of iron deposition is obscure. Hepatic tissues from control...

journal_title：Pathology international

authors： Lu JP,Hayashi K

更新日期：1995-03-01 00:00:00

abstract：:An association between autoimmune pancreatitis (AIP) and inflammatory abdominal aortic aneurysm (AAA) has never been reported. Reported herein is a case of IgG4-related inflammatory AAA accompanying metachronous AIP. A 77-year-old man presented with malaise and intermittent lower abdominal pain. Radiological examinati...

journal_title：Pathology international

authors： Ito H,Kaizaki Y,Noda Y,Fujii S,Yamamoto S

更新日期：2008-07-01 00:00:00

abstract：:The Association of Directors of Anatomic and Surgical Pathology has developed recommendations for the surgical reporting of common malignant tumors. The recommendations for prostatic carcinoma are reported herein. ...

journal_title：Pathology international

authors：

更新日期：1997-04-01 00:00:00