Phaseolus vulgaris leukoagglutinating lectin-binding reactivity in human diffuse large B-cell lymphoma and its relevance to the patient's clinical outcome: lectin histochemistry and lectin blot analysis.

abstract：:Many human colorectal adenocarcinoma cell lines have been developed. However, differentiated type colorectal cancer cell lines, particularly, the goblet-cell differentiated type, are scarce. In the present study a novel colorectal adenocarcinoma cell line (designated as COLM-6) with predominant goblet-cell differentia...

journal_title：Pathology international

authors： Yamachika T,Nakanishi H,Yasui K,Ikehara Y,Niwa T,Wanibuchi H,Tatematsu M,Fukushima S

更新日期：2005-09-01 00:00:00

abstract：:An autopsy case of an 18 month old male infant with measles infection is reported. An autopsy revealed generalized lymphadenopathy, splenomegaly and hyperplastic thymus. Histologically, there were many Warthin-Finkeldey cells (WFC) in hyperplastic lymphoid tissues. Although viral particles and inclusions were not dete...

journal_title：Pathology international

authors： Nozawa Y,Ono N,Abe M,Sakuma H,Wakasa H

更新日期：1994-06-01 00:00:00

abstract：:Conditions of preserving DNA, RNA and protein in pathological specimens are of great importance as degradation of such macromolecules would critically affect results of molecular biological analysis. The feasibility of freeze-drying as a means of preserving pathological tissue samples for molecular analysis has previo...

journal_title：Pathology international

authors： Matsuo S,Sugiyama T,Okuyama T,Yoshikawa K,Honda K,Takahashi R,Maeda S

更新日期：1999-05-01 00:00:00

abstract：:The roles of Wnt protein in carcinogenesis have been well documented in human cancers. Wls is a key modulator for the secretion of Wnt protein. We previously found that Wls was aberrantly expressed in colorectal carcinomas. Studies have revealed that dysregulation of Wnt signal transduction plays an important role in ...

journal_title：Pathology international

authors： Zhang W,Tao H,Chen X,Sugimura H,Wang J,Zhou P

更新日期：2017-03-01 00:00:00

abstract：:According to the World Health Organization classification, neoplasms with perivascular epithelioid cell differentiation (PEComas) are mesenchymal tumors composed of histologically and immunohistochemically distinctive PEC. Generally, nearly all PEComas have immunoreactivity for both melanocytic (HMB-45 and/or melan A)...

journal_title：Pathology international

authors： Adachi Y,Horie Y,Kitamura Y,Nakamura H,Taniguchi Y,Miwa K,Fujioka S,Nishimura M,Hayashi K

更新日期：2008-03-01 00:00:00

abstract：:Recent studies imply that cancer cells possess the ability to reversibly change their properties between a drug sensitive state and a drug resistant state accompanied by epigenetic changes. This evidence indicates that better understanding of cancer epigenetics is important for efficient cancer therapies. Nevertheless...

journal_title：Pathology international

authors： Matsuda Y,Semi K,Yamada Y

更新日期：2014-07-01 00:00:00

abstract：:Although a seborrheic keratosis is not rare on the skin of the trunk, extremities, head and neck of an elderly person, it is uncommon to originate in the external ear canal. Even rarer, an irritated subtype may arise in this location. We report the case of a 63-year-old man with an irritated seborrheic keratosis arisi...

journal_title：Pathology international

authors： Konishi E,Nakashima Y,Manabe T,Mazaki T,Wada Y

更新日期：2003-09-01 00:00:00

abstract：:The copper and iron status in the liver of non-tumor bearing Long-Evans Cinnamon (LEC) rats (average age 17 months) was investigated. A direct quantitation of loosely-bound copper and iron was also investigated by using a chelating agent, nitrilotriacetic acid (NTA-chelatable free copper and iron). Besides the total c...

journal_title：Pathology international

authors： Ma Y,Zhang D,Kawabata T,Kiriu T,Toyokuni S,Uchida K,Okada S

更新日期：1997-04-01 00:00:00

abstract：:Pituicytoma is a rare low-grade glial neoplasm that originates in the neurohypophysis or infundibulum. Because of its rare occurrence, the morphology and differentiation of pituicytoma have not been fully clarified. Here, we report a case of pituicytoma with unusual histological features mimicking ependymoma, but exhi...

journal_title：Pathology international

authors： Kwon MJ,Suh YL

更新日期：2011-10-01 00:00:00

abstract：:Hydatid cysts of the liver are known to occasionally rupture into the bile ducts and cause cholangitis. The histological features of this complication have not been adequately described in the literature. Herein is reported a case of severe eosinophilic cholangitis of the left hepatic lobe, occurring in a 24-year-old ...

journal_title：Pathology international

authors： Raptou G,Pliakos I,Hytiroglou P,Papavramidis S,Karkavelas G

更新日期：2009-06-01 00:00:00

abstract：:Reported herein is a case of medulloblastoma with myogenic differentiation in a 3-year-old girl who died 1 year after appearance of clinical signs. Magnetic resonance imaging indicated a mass lesion in the cerebellar vermis. She underwent total resection of the tumor, followed by chemotherapy and radiotherapy in the b...

journal_title：Pathology international

authors： Kido M,Ueno M,Onodera M,Matsumoto K,Imai T,Haba R,Tamiya T,Huang CL,Sakamoto H

更新日期：2009-04-01 00:00:00

abstract：:Immunodeficient mice are widely used for xenografts of human cells and tissue. The purpose of the present study was to investigate the characteristics of xenograft human tumor models using engraftment of various non-hematopoietic tumors in the NOD/SCID/gamma(c) (null) mouse. For tumor models, human solid tumor tissues...

journal_title：Pathology international

authors： Fujii E,Suzuki M,Matsubara K,Watanabe M,Chen YJ,Adachi K,Ohnishi Y,Tanigawa M,Tsuchiya M,Tamaoki N

更新日期：2008-09-01 00:00:00

abstract：:A case of squamous cell carcinoma arising within an acquired seminal vesicular cyst is described. A 61-year-old man was hospitalized because of hemospermia and dysuria. Under the diagnosis of a left seminal vesicular cyst, surgical resection was performed. Pathological examination revealed squamous cell carcinoma with...

journal_title：Pathology international

authors： Yanagisawa N,Saegusa M,Yoshida T,Okayasu I

更新日期：2002-03-01 00:00:00

abstract：:Changes in cerebrospinal fluid (CSF) composition have been shown to accurately reflect pathological processes in the CNS, and are potential indicators of abnormal CNS states, such as tumor growth. To detect biomarkers in high-grade astrocytomas, the differential expression of proteins in the cerebrospinal fluid was an...

journal_title：Pathology international

authors： Ohnishi M,Matsumoto T,Nagashio R,Kageyama T,Utsuki S,Oka H,Okayasu I,Sato Y

更新日期：2009-11-01 00:00:00

abstract：:An unusual case of uterine clear cell tumor is reported in a 56-year-old woman. The neoplasm was identified as a peculiar low-grade leiomyosarcoma, composed mainly of watery, clear large cells with round, fairly regular nuclei. No appreciable pleomorphism or high mitotic activity was noted. There was no necrosis. The ...

journal_title：Pathology international

authors： Karpuz V,Joris F,Letovanec N,Branchmanski F,Kapanci Y

更新日期：1998-01-01 00:00:00

abstract：:Accurate diagnosis of lymphoma includes the assessment of lineage-specific markers. Hematopoietic and lymphoid tissues express PAX5 exclusively in pro-B-cell to mature B-cell stages. However, some mature PAX5+ T-cell lymphomas have been reported. We report three cases of primary cutaneous CD30+ T-cell lymphoproliferat...

journal_title：Pathology international

authors： Hagiwara M,Tomita A,Takata K,Shimoyama Y,Yoshino T,Tomita Y,Nakamura S

更新日期：2012-04-01 00:00:00

abstract：:A case of small intestinal extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with monoclonal cryoglobulinemia is described. The patient was a woman in her mid-sixties with purpura of the bilateral lower legs and abdominal pain. An immunoserological investigation showed expre...

journal_title：Pathology international

authors： Saito T,Tamaru J,Kishi H,Kayao J,Kuzuu Y,Wakita H,Adachi A,Itoyama S,Mikata I

更新日期：2004-09-01 00:00:00

abstract：:Angioimmunoblastic T cell lymphoma (AITL) is characterized by the presence of atypical lymphocytes with clear cytoplasm and follicular dendritic cells, arborization of high endothelial blood vessels, and infiltration by inflammatory cells, such as epithelioid histiocytes, eosinophils, immunoblasts, and plasma cells. T...

journal_title：Pathology international

authors： Murakami Y,Shimada K,Kosugi H,Mori N

更新日期：2011-05-01 00:00:00

abstract：:The morphological expression of the immune response of palatine tonsils obtained from patients with pustulosis palmaris et plantaris (PPP) was investigated by morphometry in conjunction with immunohistochemistry. First, to differentiate the histological features of tonsils between PPP and habitual tonsillitis, each ex...

journal_title：Pathology international

authors： Sakai T,Kawaguchi M,Ishizawa S,Kaji T,Kitagawa K,Koizumi F

更新日期：1994-03-01 00:00:00

abstract：:Ameloblastoma is an odontogenic tumor of the jaw. It most frequently occurs in the mandible, and less often in the maxilla. Mandibular ameloblastoma harbors a BRAF mutation that causes a valine (V) to glutamic acid (E) substitution at codon 600 (BRAFV600E ). We examined specimens from 32 Japanese patients to detect th...

journal_title：Pathology international

authors： Seki-Soda M,Sano T,Ito K,Yokoo S,Oyama T

更新日期：2020-04-01 00:00:00

abstract：:Microscopic pulmonary tumor embolism is difficult to diagnose. Herein is presented the case of a patient who suffered from acute dyspnea and breast cancer on the right side. Two weeks after the breast cancer diagnosis the patient began to experience dyspnea. After 2 weeks of dyspnea, the patient died without an accura...

journal_title：Pathology international

authors： Kawasaki H,Ogura H,Arai Y,Baba S,Kosugi I,Tsutsui Y,Iwashita T

更新日期：2010-03-01 00:00:00

abstract：:A report of a 65-year-old male with a tumor arising from synovial tissue of the radio-ulnar joint. On magnetic resonance imaging, the tumor was demonstrated as a heterogeneous and lobulated mass with a low signal intensity both in T1- and T2-weighted images. Histological findings of the tumor were identical to those o...

journal_title：Pathology international

authors： Misawa A,Okada K,Hirano Y,Sageshima M

更新日期：1999-12-01 00:00:00

abstract：:Elderly patients with Epstein-Barr virus (EBV) infection are at increased risk for developing B-cell lymphoproliferative disorder (B-LPD) due to immunosenescence. Here, we describe a case of a 75-year-old man who developed an EBV-positive (EBV+) mucocutaneous ulcer (EBVMCU) in the gingiva with spontaneous regression. ...

journal_title：Pathology international

authors： Daroontum T,Kohno K,Inaguma Y,Okamoto A,Okamoto M,Kimura Y,Nagahama M,Sakakibara A,Satou A,Nakamura S

更新日期：2019-01-01 00:00:00

abstract：:The p73 gene is a member of the p53 gene family and the structure and functions of p73 protein are similar to those of p53. However, these two proteins have different roles. In the present study, p73 protein was found immunohistochemically to be distributed in the basal cells of the epidermis, columnar basal cells in ...

journal_title：Pathology international

authors： Kamiya M,Takeuchi Y,Katho M,Yokoo H,Sasaki A,Nakazato Y

更新日期：2004-12-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) is a heterodimeric polypeptide growth factor that has pleiotropic roles, including those of mitogen, motogen and morphogen. The HGF receptor is characterized as a c-Met proto-oncogene product (c-Met), which is a heterodimeric tyrosine kinase receptor. Hepatocyte growth factor acts as a m...

journal_title：Pathology international

authors： Motoi T,Ishida T,Kuroda M,Horiuchi H,Oka T,Matsumoto K,Nakamura T,Machinami R

更新日期：1998-10-01 00:00:00

abstract：:Interactions among p53, bcl-2 and Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in nasopharyngeal carcinoma (NPC) cells were evaluated by gene cotransfections. The data showed that bcl-2 expression was not only able to prevent the growth suppression induced by wild-type p53 but was also paradoxically able ...

journal_title：Pathology international

authors： Sheu LF,Chen A,Lee HS,Hsu HY,Yu DS

更新日期：2004-07-01 00:00:00

abstract：:This report describes a case of an immunocompetent 77-year-old male with Epstein-Barr virus (EBV)-positive lymphoproliferative disorder associated with calcified chronic subdural hematoma (CSH). On the day prior to consultation in our outpatient clinic, the patient fell from his bed, striking his frontal head on the f...

journal_title：Pathology international

authors： Sugita Y,Ohta M,Ohshima K,Niino D,Nakamura Y,Okada Y,Nakashima S

更新日期：2012-06-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy is an unusual malignancy-related respiratory complication characterized by multiple microthrombi and intimal myofibroblast proliferation. Its clinical manifestation is subacute respiratory failure with pulmonary hypertension. Herein is reported a case of pulmonary tumor throm...

journal_title：Pathology international

authors： Sakashita N,Yokose C,Fujii K,Matsumoto M,Ohnishi K,Takeya M

更新日期：2007-06-01 00:00:00

abstract：:Pleomorphic lobular carcinoma (PLC) of the breast is a variant of lobular carcinoma, characterized by loss of E-cadherin expression and high-grade morphologies. Whether the pathogenesis of PLC is in the ductal or the lobular lineage has been discussed. In this report, a case of PLC combined with apocrine carcinoma is ...

journal_title：Pathology international

authors： Ishii A,Oishi T,Kakuda Y,Yasui H,Kawata T,Muramatsu K,Takahashi K,Sugino T

更新日期：2019-05-01 00:00:00

abstract：:Humoral factors from cancer-associated fibroblasts (CAFs) reportedly affect epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance in cancer cells with EGFR mutations. The aim of this study was to identify the robust humoral factors secreted from CAFs that induce the primary resistance to EGF...

journal_title：Pathology international

authors： Suzuki E,Yamazaki S,Naito T,Hashimoto H,Okubo S,Udagawa H,Goto K,Tsuboi M,Ochiai A,Ishii G

更新日期：2019-08-01 00:00:00