Abstract:
:A case is reported of intra-abdominal desmoplastic small cell tumor (IDSCT) with biphasic histologic features in a patient with proximal spinal muscular atrophy. The tumor was composed of small epithelial cell nests with spindle cell sarcomatous areas. Both areas were surrounded by a desmoplastic stroma. Immunohistochemical studies revealed reactivity for low molecular weight cytokeratin, epithelial membrane antigen, vimentin, desmin and Leu-7 in both areas. Electron microscopic examination demonstrated paranuclear aggregates of intermediate filaments, zonula adherens and basement membrane-like material in the epithelial cells, while spindle cells in the tumor had fewer intracytoplasmic organelles. However, intermediate or transitional forms of both types of tumor cells were frequently observed. Although IDSCT are known to express multi-phenotypes immunohistochemically, attention should be paid to the broad spectrum of cell morphology in these tumors.
journal_name
Pathol Intjournal_title
Pathology internationalauthors
Motoyama T,Maejima T,Aizawa K,Fukuda T,Watanabe Hdoi
10.1111/j.1440-1827.1996.tb03533.xsubject
Has Abstractpub_date
1996-01-01 00:00:00pages
54-9issue
1eissn
1320-5463issn
1440-1827journal_volume
46pub_type
杂志文章abstract::A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobect...
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journal_title:Pathology international
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journal_title:Pathology international
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journal_title:Pathology international
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journal_title:Pathology international
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