Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change.

abstract：:Morphologic, immunohistochemical and immunogenetic studies were performed on 28 cases of primary gastric lymphoma from fresh frozen tissue. Eight cases were diagnosed as diffuse large B-cell lymphoma, four as follicular center lymphoma (follicular), five as mucosa-associated lymphoid tissue (MALT) lymphoma, three as p...

journal_title：Pathology international

authors： Narita M,Yatabe Y,Asai J,Mori N

更新日期：1996-09-01 00:00:00

abstract：:The CDKN2 gene encodes two structurally different proteins: a cyclin-dependent kinase inhibitor, p16, which regulates retinoblastoma protein (pRb)-dependent G1 arrest, and a cell cycle inhibitor, p14ARF, which blocks MDM2-induced p53 degradation resulting in an increase in p53 levels that leads to cell cycle arrest. R...

journal_title：Pathology international

authors： Sano T,Masuda N,Oyama T,Nakajima T

更新日期：2002-05-01 00:00:00

abstract：:Adenosquamous carcinoma (ASC) is a rare malignant neoplasm of the head and neck regions. We elucidated the relationship between ASC and MUC molecule expression. We selected 14 cases of ASC in the head and neck, and examined them immunohistohcmically. Seven cases of tongue, 3 cases of larynx and 4 cases of hypopharynx ...

journal_title：Pathology international

authors： Kusafuka K,Muramatsu K,Iida Y,Mori K,Miki T,Suda T,Fuke T,Kamijo T,Onitsuka T,Nakajima T

更新日期：2014-03-01 00:00:00

abstract：:The authors investigated the protein expression of double-stranded RNA-activated protein kinase (PKR), which was identified by using a previous cDNA microarray study, to discover PKR's correlations with several pathological parameters and to elucidate its role in neoplastic transformation and progression of lung adeno...

journal_title：Pathology international

authors： Roh MS,Kwak JY,Kim SJ,Lee HW,Kwon HC,Hwang TH,Choi PJ,Hong YS

更新日期：2005-11-01 00:00:00

abstract：:Differentiation of malignant pleural mesothelioma (MPM) from benign mesothelial proliferation remains problematic. Loss of nuclear staining of BRCA1-associated protein 1 (BAP1; detected using immunohistochemistry (IHC)) and homozygous deletion (HD) of p16 (detected using fluorescence in situ hybridization (FISH)) are ...

journal_title：Pathology international

authors： Hida T,Hamasaki M,Matsumoto S,Sato A,Tsujimura T,Kawahara K,Iwasaki A,Okamoto T,Oda Y,Honda H,Nabeshima K

更新日期：2016-10-01 00:00:00

abstract：:The Association of Directors of Anatomic and Surgical Pathology have developed recommendations for the surgical pathology reporting of common malignant tumors. The recommendations for carcinomas of the urinary bladder are reported herein. ...

journal_title：Pathology international

authors：

更新日期：1997-05-01 00:00:00

abstract：:Cellular senescence is defined as irreversible cell arrest and could work as a safeguard against tumorigenesis. This mechanism was examined in chronic viral hepatitis-related hepatocarcinogenesis. By using surgical resected or wedge biopsied liver specimens from 87 chronic viral hepatitis patients in whom 35 neoplasti...

journal_title：Pathology international

authors： Ikeda H,Sasaki M,Sato Y,Harada K,Zen Y,Mitsui T,Nakanuma Y

更新日期：2009-07-01 00:00:00

abstract：:A case of ovarian fibrosarcoma producing multiple cytokines is presented. The tumor occurred in the left ovary of a Japanese woman with epigastralgia, remittent fever, leukocytosis and slight thrombocytosis with moderate increase of mast cells in bone marrow, but lack of hormonal abnormality. The resected tumor of the...

journal_title：Pathology international

authors： Fukuda T,Yamaguchi T,Yamaki T,Suzuki T

更新日期：2001-09-01 00:00:00

abstract：:Leiomyomatosis peritonealis disseminata (LPD) is a rare clinicopathological entity typically observed in women of reproductive age. We report a case of LPD with malignant change in a man. A 77-year-old man presented with a mass measuring 10 cm in diameter at the terminal ileum and numerous peritoneal small nodules tha...

journal_title：Pathology international

authors： Yamaguchi T,Imamura Y,Yamamoto T,Fukuda M

更新日期：2003-03-01 00:00:00

abstract：:Anomalous pancreaticobiliary junction (APBJ) is a congenital anomaly in which the pancreatic duct joins the common bile duct proximal to the sphincter of Oddi. Anatomical and immunohistochemical examination of the pancreas with APBJ has rarely been performed. A 72-year-old woman with gallbladder cancer and APBJ died o...

journal_title：Pathology international

authors： Tadokoro H,Takase M,Nobukawa B

更新日期：2008-08-01 00:00:00

abstract：:This study aims to evaluate the impact on the implementation of multiple strategies to improve medical student's pathology learning experience. In two consecutive years, medical students after a whole year of enrolling in pathology teaching, were invited to complete questionnaires rating and commenting on the personal...

journal_title：Pathology international

authors： Gopalan V,Kasem K,Pillai S,Olveda D,Ariana A,Leung M,Lam AKY

更新日期：2018-07-24 00:00:00

abstract：:Malignant myoepithelioma of soft tissue is extremely rare. Presented herein is a case arising in a 17-year-old man. The tumor was initially noticed as a painless deep soft-tissue mass in the right forearm when the patient was aged 3 years. Thereafter, it grew without remarkable symptoms, such as pain or tenderness, un...

journal_title：Pathology international

authors： Harada O,Ota H,Nakayama J

更新日期：2005-08-01 00:00:00

abstract：:Methotrexate (MTX) is currently used as first-line anchor drug for rheumatoid arthritis (RA). Therefore, the number of MTX-associated lymphoproliferative disorders, including Epstein-Barr virus-positive mucocutaneous ulcer (EBVMCU), has increased. Some aspects of MTX-associated EBVMCU (MTX-EBVMCU), particularly clinic...

journal_title：Pathology international

authors： Satou A,Banno S,Hanamura I,Takahashi E,Takahara T,Nobata H,Katsuno T,Takami A,Ito Y,Ueda R,Nakamura S,Tsuzuki T

更新日期：2019-01-01 00:00:00

abstract：:Eight hepatic atypical adenomatous hyperplasias (AH), 30 hepatocellular carcinomas (HCC) consisting of 11 well-, 13 moderately and six poorly differentiated HCC, and 10 intrahepatic cholangiocarcinomas (CC) were investigated immunohistochemically with anti-alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), CA19-...

journal_title：Pathology international

authors： Tsuji M,Kashihara T,Terada N,Mori H

更新日期：1999-04-01 00:00:00

abstract：:Infantile myofibromatosis (IM) is a rare disorder present at birth or in early infancy with a biphasic histological pattern. We present a neonatal-onset case of generalized IM with visceral (central nervous system, heart, lungs, liver, spleen, small intestine, kidneys and bones) and placental involvement, showing a mo...

journal_title：Pathology international

authors： Iwafuchi H,Tsuzuki T,Ito R,Miyake H,Okita H,Hamazaki M

更新日期：2015-08-01 00:00:00

abstract：:We established a dedifferentiated liposarcoma cell line (NDDLS-1) that produces interleukin-6 (IL-6) and granulocyte-colony stimulating factor (G-CSF). The parental tumor showed high leukemoid reactions. The NDDLS-1 cell line was established from a pleural effusion associated with a lung metastasis. Pleomorphic tumor ...

journal_title：Pathology international

authors： Ariizumi T,Ogose A,Kawashima H,Hotta T,Li G,Xu Y,Hirose T,Endo N

更新日期：2011-08-01 00:00:00

abstract：:The KIT, epidermal growth factor receptor (EGFR) and HER-2 oncoproteins have tyrosine kinase activity and are molecular targets in human cancer therapy. To clarify the significance of KIT, EGFR, and HER-2 in undifferentiated thyroid carcinoma (UTC), the expression of these receptors and tyrosine phosphorylation was ex...

journal_title：Pathology international

authors： Murakawa T,Tsuda H,Tanimoto T,Tanabe T,Kitahara S,Matsubara O

更新日期：2005-12-01 00:00:00

abstract：:Telomerase activity is thought to contribute to the immortality of cancers. Recently, some investigators described a correlation between the activity of telomerase and the proliferative activity of cancer cells. The aim of this study was to evaluate the correlation between the expression of telomerase-associated prote...

journal_title：Pathology international

authors： Ikeda S,Shibata T,Eishi Y,Takizawa T,Koike M

更新日期：2003-11-01 00:00:00

abstract：:Nodular fasciitis (NF) is a self-limiting benign disease that is characterized by rapid proliferation of fibroblastic and myofibroblastic cells. The characteristic gene fusion containing the USP6 gene is a genetic hallmark of NF and MYH9-USP6 is the most frequent fusion, suggesting that NF is not a reactive condition ...

journal_title：Pathology international

authors： Teramura Y,Yamazaki Y,Tanaka M,Sugiura Y,Takazawa Y,Takeuchi K,Nakayama T,Kaneko T,Musha Y,Funauchi Y,Ae K,Matsumoto S,Nakamura T

更新日期：2019-12-01 00:00:00

abstract：:Although a seborrheic keratosis is not rare on the skin of the trunk, extremities, head and neck of an elderly person, it is uncommon to originate in the external ear canal. Even rarer, an irritated subtype may arise in this location. We report the case of a 63-year-old man with an irritated seborrheic keratosis arisi...

journal_title：Pathology international

authors： Konishi E,Nakashima Y,Manabe T,Mazaki T,Wada Y

更新日期：2003-09-01 00:00:00

abstract：:Therapy related acute lymphoblastic leukemia (t-ALL) of B cell origin is rare and constitutes approximately 2% of all ALL. Previously compiled data on the complete cytogenetic analysis of 48 t-B-ALL cases suggested that MLL rearrangement at 11q23 gene locus is the most common abnormality. Philadelphia chromosome (Ph) ...

journal_title：Pathology international

authors： Matnani R,Parekh V,Borate U,Brazelton J,Reddy V,Peker D

更新日期：2015-10-01 00:00:00

abstract：:Pulmonary papillary adenoma is a rare tumor. We analyzed a tumor which appeared in a 16-year-old Japanese woman. The tumor histologically showed papillary proliferation of one-layered tumor cells coating inflammatory fibrovascular cores. At the periphery of the tumor, the tumor cells grew in a lepidic fashion. The tum...

journal_title：Pathology international

authors： Masunaga A,Nagashio R,Iwamoto S,Takeyama N,Sato Y,Miyazaki A,Mitsuya T

更新日期：2012-09-01 00:00:00

abstract：:In papillary thyroid carcinoma (PTC) in cytological and surgical specimens, fine chromatin, nuclear grooves and nuclear pseudoinclusions are the hallmarks of diagnosis. We investigated the significance of these nuclear changes in neoplastic non-PTC lesions. Fine needle aspiration biopsies (FNAB) of thyroid lesions wer...

journal_title：Pathology international

authors： Mai KT,Yazdi HM,Commons AS,Perkins DG,MacDonald L

更新日期：1999-07-01 00:00:00

abstract：:The aim of the present study was to clarify protein profiling in small cell lung carcinoma (SCLC) and pulmonary large cell neuroendocrine carcinoma (LCNEC). The proteomic approach was used, and involved cell lysate from two cell lines (N231 derived from SCLC and LCN1 derived from LCNEC), with 2-D gel electrophoresis (...

journal_title：Pathology international

authors： Nagashio R,Sato Y,Matsumoto T,Kageyama T,Satoh Y,Ryuge S,Masuda N,Jiang SX,Okayasu I

更新日期：2010-02-01 00:00:00

abstract：:An extremely rare case of malignant mesothelioma of the pericardium is reported. The tumor appeared to be the biphasic type of diffuse malignant mesothelioma which present many small to fine lipid droplets in the cytoplasm, particularly that of the epithelial cell, and a positive immunohistochemical reaction with anti...

journal_title：Pathology international

authors： Ohmori T,Arita N,Okada K,Kondo M,Tabei R

更新日期：1995-08-01 00:00:00

abstract：:The biologic behavior of gastrointestinal stromal tumors is difficult to predict, and they can be best studied in a site-specific fashion. The aims of this study are to analyze the clinicopathologic parameters and assess the prognostic value of p53 (DO-7) and Ki-67 (MIB-1) immunoreactivities in small intestinal stroma...

journal_title：Pathology international

authors： Chang MS,Choe G,Kim WH,Kim YI

更新日期：1998-05-01 00:00:00

abstract：:The role of chemokines, especially CXCL10/interferon-gamma-inducible protein 10 kDa (IP-10), a chemokine to attract CXCR3(+) T-helper 1-type CD4(+) T cells, is largely unknown in the pathophysiology of inflammatory bowel disease; ulcerative colitis and Crohn's disease. The authors have earlier shown that IP-10 neutral...

journal_title：Pathology international

authors： Suzuki K,Kawauchi Y,Palaniyandi SS,Veeraveedu PT,Fujii M,Yamagiwa S,Yoneyama H,Han GD,Kawachi H,Okada Y,Ajioka Y,Watanabe K,Hosono M,Asakura H,Aoyagi Y,Narumi S

更新日期：2007-07-01 00:00:00

abstract：:We report a case of glomerular cystic kidney disease (GCKD) associated with tuberous sclerosis complex (TSC) in a neonate. The patient displayed progressive abdominal enlargement attributed to GCKD associated with TSC. After birth, the right kidney was resected because it compressed his liver and right lung, and possi...

journal_title：Pathology international

authors： Murakami A,Gomi K,Tanaka M,Ohyama M,Itani Y,Ishikawa H,Aida N,Furuya M,Tanaka Y

更新日期：2012-03-01 00:00:00

abstract：:Multiple myeloma (MM) is a plasma-cell neoplasm that can cause renal disorders. Renal lesions in MM can present with a very rare pathological manifestation involving a specific monoclonal immunoglobulin (Ig). We report the case of a 33-year-old woman who had edema, fatigue, elevated serum creatinine levels, hypoalbumi...

journal_title：Pathology international

authors： Watanabe H,Osawa Y,Goto S,Habuka M,Imai N,Ito Y,Hirose T,Chou T,Ohashi R,Shimizu A,Ehara T,Shimotori T,Narita I

更新日期：2015-01-01 00:00:00

abstract：:A 70-year-old man with metastatic liver tumors showed carcinoid syndrome with clinical symptoms of facial flushing, palpitation, dyspnea, and an itching sensation. Regurgitation of the tricuspid and aortic valves was observed by echocardiography. An elevated serum level of serotonin and a high urine excretion of serot...

journal_title：Pathology international

authors： Sakai D,Murakami M,Kawazoe K,Tsutsumi Y

更新日期：2000-05-01 00:00:00