Primary gastric lymphomas: morphologic, immunohistochemical and immunogenetic analyses.

abstract：:A 56-year-old male treated for a gastric yolk sac tumor with an adenocarcinomatous component is described. A mixed area of reticular and glandular neoplastic components was morphologically identified in this tumor. Immunohistochemically, the yolk sac tumor expressed alpha-fetoprotein (AFP), placental alkaline phosphat...

journal_title：Pathology international

authors： Suzuki T,Kimura N,Shizawa S,Yabuki N,Yamaki T,Sasano H,Nagura H

更新日期：1999-06-01 00:00:00

abstract：:Of the idiopathic interstitial pneumonias (IIPs), usual interstitial pneumonia (UIP) and diffuse alveolar damage (DAD) usually have poor prognoses. The prognoses of cryptogenic organizing pneumonia (COP) and nonspecific interstitial pneumonia (NSIP) are usually more favorable. Although several reports have described n...

journal_title：Pathology international

authors： Takahashi M,Kunugi S,Terasaki Y,Terasaki M,Urushiyama H,Kuwahara N,Wakamatsu K,Nakayama T,Fukuda Y

更新日期：2013-05-01 00:00:00

abstract：:Autosomal recessive polycystic kidney disease (ARPKD) is caused by genetic mutations of the gene encoding fibrocystin, and is characterized by the collecting duct cysts and congenital hepatic fibrosis. We report an autopsy-proven case of ARPKD in a 77-year-old male who presented with rapidly progressive renal and live...

journal_title：Pathology international

authors： Taneda S,Honda K,Aoki A,Nitta K,Tamura T,Yoshioka Y,Oda H

更新日期：2012-12-01 00:00:00

abstract：:We describe a rare case of dedifferentiated liposarcoma with features resembling chondroblastic osteosarcoma in the dedifferentiated component. The tumor was removed from the left thigh in a 78-year-old male. It consisted of a well-differentiated liposarcoma and an anaplastic component that contained numerous osteoid ...

journal_title：Pathology international

authors： Yamamoto T,Matsushita T,Marui T,Mizuno K,Minami R,Hayashi Y,Hanioka K

更新日期：2000-07-01 00:00:00

abstract：:Calcifying fibrous tumor (CFT) is an uncommon lesion of uncertain cause and pathogenesis that has a unique histological appearance. These lesions are described mainly in the subcutaneous or deep soft tissues, followed by subserosal locations. Intrinsic visceral CFT is extremely rare. Herein is described a rare case of...

journal_title：Pathology international

authors： Elpek GO,Küpesiz GY,Ogüs M

更新日期：2006-04-01 00:00:00

abstract：:Humoral factors from cancer-associated fibroblasts (CAFs) reportedly affect epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance in cancer cells with EGFR mutations. The aim of this study was to identify the robust humoral factors secreted from CAFs that induce the primary resistance to EGF...

journal_title：Pathology international

authors： Suzuki E,Yamazaki S,Naito T,Hashimoto H,Okubo S,Udagawa H,Goto K,Tsuboi M,Ochiai A,Ishii G

更新日期：2019-08-01 00:00:00

abstract：:Alterations in cell surface carbohydrates on human lymphoma cell lines with different spontaneous metastatic potential in the severe combined immunodeficiency (SCID) mouse model were analyzed. A difference in cell surface carbohydrates between high- (HBL-2, HBL-7 and HBL-8) and no- or low-(HBL-4, HBL-6, Daudi and Raji...

journal_title：Pathology international

authors： Abe M,Suzuki O,Tasaki K,Tominaga K,Wakasa H

更新日期：1996-12-01 00:00:00

abstract：:This study aims to evaluate the impact on the implementation of multiple strategies to improve medical student's pathology learning experience. In two consecutive years, medical students after a whole year of enrolling in pathology teaching, were invited to complete questionnaires rating and commenting on the personal...

journal_title：Pathology international

authors： Gopalan V,Kasem K,Pillai S,Olveda D,Ariana A,Leung M,Lam AKY

更新日期：2018-07-24 00:00:00

abstract：:A rare case of an extragonadal teratoma, which occurred primarily in the uterus, is described. The tumor developed in the uterine cervix as a conventional cervical polyp, 3 months after an elective abortion in a 27-year-old woman. Microscopically, the solid 2.2 x 1.8 x 1.5 cm mass was a mature teratoma with exuberant ...

journal_title：Pathology international

authors： Lim SC,Kim YS,Lee YH,Lee MS,Lim JY

更新日期：2003-05-01 00:00:00

abstract：:Hepatic ultrasonic transient elastography (FibroScan) is a new diagnostic method for the assessment of hepatic fibrosis. There are limited data available on its use as a follow-up tool for patients with chronic hepatitis B. In this study, 134 patients were enrolled. Hepatic fibrosis was evaluated by liver stiffness me...

journal_title：Pathology international

authors： Zhang YG,Wang BE,Wang TL,Ou XJ

更新日期：2010-04-01 00:00:00

abstract：:A complete spontaneous regression of diffuse large B cell lymphoma involving the right breast, confirmed by aspiration cytology, is reported. The patient visited a hospital due to the rapid growth of a tumor in the right breast. Five years previously she underwent a craniotomy for a brain tumor, diagnosed as B-cell ma...

journal_title：Pathology international

authors： Iihara K,Yamaguchi K,Nishimura Y,Iwasaki T,Suzuki K,Hirabayashi Y

更新日期：2004-07-01 00:00:00

abstract：:We have found that the MIB-1 grade, based on tumor differentiation/histological type, necrosis and Ki-67 (MIB-1) score, is a valid and reproducible prognostic system for adult soft-tissue sarcomas. However, there are limited data available on Ki-67 labeling indices (LI) from adult soft-tissue sarcomas for testing the ...

journal_title：Pathology international

authors： Hasegawa T,Yamamoto S,Matsuno Y

更新日期：2002-07-01 00:00:00

abstract：:Herein is presented a case of carcinosarcoma of the pancreas in an 82-year-old woman, analyzed on immunohistochemistry and K-ras sequence. The tumor, which arose in the pancreas head, was removed on pancreaticoduodenectomy. The patient died, however, of disseminated intravascular coagulation syndrome from postoperativ...

journal_title：Pathology international

authors： Nakano T,Sonobe H,Usui T,Yamanaka K,Ishizuka T,Nishimura E,Hanazaki K

更新日期：2008-10-01 00:00:00

abstract：:A case of primary esophageal adenocarcinoma in a 64-year-old man is reported. An ulcerating tumor was located in the middle intrathoracic esophagus. Histopathological examination revealed a moderately differentiated adenocarcinoma, which had invaded down to the adventitia. The cancerous tubuli were lined by flattened ...

journal_title：Pathology international

authors： Endoh Y,Miyawaki M,Tamura G,Watanabe H,Motoyama T

更新日期：1999-02-01 00:00:00

abstract：:A 54-year-old Japanese woman was referred with a gallbladder tumor. Based on the results of the computed tomography scan, endoscopic retrograde cholangiopancreatography, and magnetic resonance cholangiopancreatography, a mucin-producing neoplasm of the gallbladder associated with pancreaticobiliary maljunction was dia...

journal_title：Pathology international

authors： Meguro Y,Fukushima N,Koizumi M,Kasahara N,Hydo M,Morishima K,Sata N,Lefor AT,Yasuda Y

更新日期：2014-09-01 00:00:00

abstract：:Stenosing flexor tenosynovitis, trigger finger, is a common clinical disorder causing painful locking or contracture of the involved digits, and most instances are idiopathic. This problem is generally caused by a size mismatch between the swollen flexor tendon and the thickened first annular pulley. Although hypertro...

journal_title：Pathology international

authors： Uchihashi K,Tsuruta T,Mine H,Aoki S,Nishijima-Matsunobu A,Yamamoto M,Kuraoka A,Toda S

更新日期：2014-06-01 00:00:00

abstract：:Changes in cerebrospinal fluid (CSF) composition have been shown to accurately reflect pathological processes in the CNS, and are potential indicators of abnormal CNS states, such as tumor growth. To detect biomarkers in high-grade astrocytomas, the differential expression of proteins in the cerebrospinal fluid was an...

journal_title：Pathology international

authors： Ohnishi M,Matsumoto T,Nagashio R,Kageyama T,Utsuki S,Oka H,Okayasu I,Sato Y

更新日期：2009-11-01 00:00:00

abstract：:CpG island methylator phenotype (CIMP) is a recently described subset of colorectal cancers (CRC) with widespread methylation of multiple promoter CpG islands. But the prognostic implication of CIMP in CRC has not been clarified. Thus, the aim of the present study was to differentiate the unique characteristics of CIM...

journal_title：Pathology international

authors： Lee S,Cho NY,Choi M,Yoo EJ,Kim JH,Kang GH

更新日期：2008-02-01 00:00:00

abstract：:Reported herein is a case of benign clear cell tumor of the lung in a 60-year-old man. Chest X-ray and CT examination revealed an abnormal nodule with homogenous density and a clear margin in the lower lobe of the left lung. The resected tumor was 13 mm in size, well-circumscribed and was graysh-white on cut surface. ...

journal_title：Pathology international

authors： Adachi Y,Kitamura Y,Nakamura H,Taniguchi Y,Miwa K,Horie Y,Hayashi K

更新日期：2006-08-01 00:00:00

abstract：:A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobect...

journal_title：Pathology international

authors： Zhang Z,Nonaka H,Nagayama T,Hatori T,Ihara F,Zhang L,Akima M,Shiba T

更新日期：2001-12-01 00:00:00

abstract：:The occurrence of malignant neoplasms increases with advancing age. Although aging and carcinogenesis are basically different processes, there are phenomena common to each such as accumulation of DNA damage and abnormal proteins. Gastric and colorectal carcinomas are representative tumors in which the prevalence and t...

journal_title：Pathology international

authors： Arai T,Takubo K

更新日期：2007-06-01 00:00:00

abstract：:The purpose of the present study was to determine whether the amount and the location of residual tumor are associated with outcome in surgically treated rectal cancer patients who receive preoperative chemoradiation therapy. Forty-three rectal cancer patients who underwent sphincter-saving operations after preoperati...

journal_title：Pathology international

authors： Kojima M,Ishii G,Yamane Y,Nishizawa Y,Saito N,Ochiai A

更新日期：2009-12-01 00:00:00

abstract：:So-called 'hybrid' lesion of ameloblastoma, which is composed of desmoplastic ameloblastoma and conventional follicular/plexiform ameloblastoma, is an unusual variant of ameloblastoma and only eight cases of 'hybrid' lesion have been published in the English literature. To enhance knowledge of this interesting tumor, ...

journal_title：Pathology international

authors： Takata T,Miyauchi M,Ogawa I,Zhao M,Kudo Y,Sato S,Takekoshi T,Nikai H,Tanimoto K

更新日期：1999-11-01 00:00:00

abstract：:The effects of traditional Chinese medicine (Sairei-to) on experimental glomerulonephritis induced in rats by monoclonal antibody (mAb) 1-22-3 injection was examined. The level of proteinuria in the Sairei-to-treated group was significantly lower than that in the PBS treated group. This suppressive effect was caused b...

journal_title：Pathology international

authors： Li P,Kawachi H,Morioka T,Orikasa M,Oite T,Shi ZS,Shimizu F

更新日期：1997-07-01 00:00:00

abstract：:YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...

journal_title：Pathology international

authors： Fukuda T,Kamishima T,Kakihara T,Yamada T,Matsumoto K,Uchiyama M,Suzuki T

更新日期：1997-08-01 00:00:00

abstract：:Tec is a novel non-receptor-type protein tyrosine kinase that was originally identified from a murine liver cDNA library. While the function of Tec remains unknown, it was shown recently that two Tec-related kinases are involved directly in the growth and differentiation of bone marrow stem cells. As the localization ...

journal_title：Pathology international

authors： Kazama A,Mano H,Morishita Y,Mori S

更新日期：1996-05-01 00:00:00

abstract：:Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare genetic disorder characterized by cutaneous and uterine leiomyomatosis with RCC. This disorder is caused by a germline mutation in the fumarate hydratase (FH) gene, which encodes an important enzyme of the tricarboxylic acid (TCA) cycle. This mutation d...

journal_title：Pathology international

authors： Matsumoto K,Udaka N,Hasumi H,Nakaigawa N,Nagashima Y,Tanaka R,Kato I,Yao M,Furuya M

更新日期：2018-05-24 00:00:00

abstract：:Solitary fibrous tumor of the pleura (SFTP) is rare. A 73-year-old man, without past history of diabetes mellitus, was admitted to hospital with profound hypoglycemia, loss of consciousness and respiratory failure. CT indicated a huge heterogenous mass lesion (12 x 12 x 17 cm) at the right thoracic cavity with total a...

journal_title：Pathology international

authors： Chang JC,Su KY,Chao SF,Hsu YH,Yang GG,Chang BS

更新日期：2007-12-01 00:00:00

abstract：:The chemokine receptor CXCR4 belongs to the large superfamily of G protein-coupled receptors and has been identified to play a crucial role in a number of biological processes, including the trafficking and homeostasis of immune cells such as T lymphocytes. CXCR4 has also been found to be a prognostic marker in variou...

journal_title：Pathology international

authors： Furusato B,Mohamed A,Uhlén M,Rhim JS

更新日期：2010-07-01 00:00:00

abstract：:An 18-year-old man who suffered from panniculitis involving the entire left lower limb after exertional rhabdomyolysis is reported. A high fever (>39 degrees C) and leukocytosis (>20,000/microL) persisted for 1 week, and his general status deteriorated rapidly into pre-disseminated intravascular coagulation, complicat...

journal_title：Pathology international

authors： Kanai Y,Iwaya K,Kuroda M,Harada M,Hirata F,Mukai K

更新日期：2000-10-01 00:00:00