Clinicopathological and molecular characteristics of gastric and colorectal carcinomas in the elderly.

abstract：:We report 17 cases of the classic type of Kaposi's sarcoma in Xinjiang, which is located in the north-western area of China surrounded by Mongolia in the east, Russia in the north and Kazakhstan in the west. Fifteen of the patients were of the Uygur people. All patients were male and did not have acquired immunodefici...

journal_title：Pathology international

authors： Dilnur P,Katano H,Wang ZH,Osakabe Y,Kudo M,Sata T,Ebihara Y

更新日期：2001-11-01 00:00:00

abstract：:To test whether a subset of esophageal squamous cell carcinomas (SCC) develop through a deficiency in DNA mismatch repair, we examined microsatellite instability (MSI) using 11 microsatellite markers including BAT-26, hMLH1 protein expression by immunohistochemistry, and methylation status of the hMLH1 promoter by met...

journal_title：Pathology international

authors： Hayashi M,Tamura G,Jin Z,Kato I,Sato M,Shibuya Y,Yang S,Motoyama T

更新日期：2003-05-01 00:00:00

abstract：:An unusual case of cystic renal cell carcinoma in a 70-year-old Japanese male is reported. He had had a simple renal cyst removed 1 year ago. On presentation the right kidney was surrounded by multiple translucent cysts, which varied in size from 1 to 50 mm. The cyst walls were lined by single-layered cuboidal epithel...

journal_title：Pathology international

authors： Shishikura Y,Furusato M,Aizawa S

更新日期：1998-08-01 00:00:00

abstract：:The purpose of the present study was to clarify the difference of expression of two stem cell markers, nestin and c-kit, among various pancreatic epithelial tumors and evaluate their utility. Immunohistochemistry was done for 99 surgically resected pancreatic tumor specimens, including 20 ductal adenocarcinoma (DAC), ...

journal_title：Pathology international

authors： Ohike N,Sato M,Hisayuki T,Imataka H,Sato S,Wada Y,Saito K,Takahashi M,Tajiri T,Kunimura T,Morohoshi T

更新日期：2007-09-01 00:00:00

abstract：:Senescence marker protein 30 (SMP 30) is preferentially expressed in the liver. One of its remarkable functions is the protection of cells against various injuries by enhancement of membrane calcium-pump activity. We analyzed the role of SMP 30 in hepatocyte proliferation. SMP 30 expression was decreased initially, th...

journal_title：Pathology international

authors： Ishigami T,Fujita T,Simbula G,Columbano A,Kikuchi K,Ishigami A,Shimosawa T,Arakawa Y,Maruyama N

更新日期：2001-07-01 00:00:00

abstract：:An autopsy case of an 18 month old male infant with measles infection is reported. An autopsy revealed generalized lymphadenopathy, splenomegaly and hyperplastic thymus. Histologically, there were many Warthin-Finkeldey cells (WFC) in hyperplastic lymphoid tissues. Although viral particles and inclusions were not dete...

journal_title：Pathology international

authors： Nozawa Y,Ono N,Abe M,Sakuma H,Wakasa H

更新日期：1994-06-01 00:00:00

abstract：:A subcutaneous myopericytoma-type perivascular myoma arising in the elbow of a 61-year-old woman is described. The tumor was well demarcated and consisted microscopically of small ovoid and spindle cells arranged in a concentric fashion, surrounding small to medium-sized vessels and imparting a superficial resemblance...

journal_title：Pathology international

authors： Mikami Y,Shiomi T,Manabe T

更新日期：2002-01-01 00:00:00

abstract：:Presented herein are two unusual epithelioid angiomyolipomas (AML) displaying prominent stromal sclerosis. Both patients were middle-aged women without a clinical history of tuberous sclerosis. One patient (case 1) had a 2 cm lesion arising in the renal cortex, and another (case 2) had a pararenal retroperitoneal tumo...

journal_title：Pathology international

authors： Matsuyama A,Hisaoka M,Ichikawa K,Fujimori T,Udo K,Uchihashi K,Aoki S,Hashimoto H

更新日期：2008-05-01 00:00:00

abstract：:A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed. A small pleural nodule was incidentally found during a thoracic operation in a 54-year-old woman with esophageal cancer. The patient had no history of exposure to asbestos, and ...

journal_title：Pathology international

authors： Minato H,Nojima T,Kurose N,Kinoshita E

更新日期：2009-08-01 00:00:00

abstract：:Microscopic colitis (MC), encompassing collagenous colitis and lymphocytic colitis, is featured by chronic diarrhea, normal-looking endoscopic findings and unique microscopic appearance. After reviewing biopsied nonspecific colitis, we propose the third type of MC: colitis nucleomigrans (CN). Histopathological criteri...

journal_title：Pathology international

authors： Tachibana M,Hanaoka T,Watanabe S,Matsushita M,Isono T,Tsutsumi Y

更新日期：2020-10-01 00:00:00

abstract：:Computerized morphometrical measurements were made of liver cells and their nuclei taken from biopsy specimens of primary biliary cirrhosis (PBC), alcoholic cirrhosis, posthepatitic cirrhosis (HBV-related), and hepatocellular carcinoma (HCC). The specimens were stained with hematoxylin-eosin (HE), Mallory's stain for ...

journal_title：Pathology international

authors： Rahman SM,Itakura H,Motoda A

更新日期：1996-04-01 00:00:00

abstract：:The clinical and pathological significance of intratumoral lymphangiogenesis (ITL) with human esophageal squamous cell carcinomas (ESCC) remains unclear, as does the role of signaling molecules such as vascular endothelial growth factor (VEGF)-A,C, platelet-derived growth factor (PDGF)-A, and p53, in the regulation of...

journal_title：Pathology international

authors： Inoue A,Moriya H,Katada N,Tanabe S,Kobayashi N,Watanabe M,Okayasu I,Ohbu M

更新日期：2008-10-01 00:00:00

abstract：:An electron microscopic study of peripheral leukocytes obtained from a 39 year old woman with Hermansky-Pudlak syndrome was performed. Ceroid pigment granules were found within the lysosomes in 3.5% of monocytes and 5.4% of lymphocytes. Infrequently, pigment granules were also found in the parallel tubular arrays of l...

journal_title：Pathology international

authors： Sakuma T,Monma N,Satodate R,Satoh T,Takeda R,Kuriya S

更新日期：1995-11-01 00:00:00

abstract：:A cytometrical image analyzing method for nuclear protein was established using WinROOF, a commercially available, inexpensive software, to determine the status of both estrogen and progesterone receptors. Immunohistochemical evaluation of estrogen receptors (ER) and progesterone receptors (PR) was performed with the ...

journal_title：Pathology international

authors： Hatanaka Y,Hashizume K,Nitta K,Kato T,Itoh I,Tani Y

更新日期：2003-10-01 00:00:00

abstract：:Microscopic pulmonary tumor embolism is difficult to diagnose. Herein is presented the case of a patient who suffered from acute dyspnea and breast cancer on the right side. Two weeks after the breast cancer diagnosis the patient began to experience dyspnea. After 2 weeks of dyspnea, the patient died without an accura...

journal_title：Pathology international

authors： Kawasaki H,Ogura H,Arai Y,Baba S,Kosugi I,Tsutsui Y,Iwashita T

更新日期：2010-03-01 00:00:00

abstract：:Reported herein is a case of benign clear cell tumor of the lung in a 60-year-old man. Chest X-ray and CT examination revealed an abnormal nodule with homogenous density and a clear margin in the lower lobe of the left lung. The resected tumor was 13 mm in size, well-circumscribed and was graysh-white on cut surface. ...

journal_title：Pathology international

authors： Adachi Y,Kitamura Y,Nakamura H,Taniguchi Y,Miwa K,Horie Y,Hayashi K

更新日期：2006-08-01 00:00:00

abstract：:Therapy related acute lymphoblastic leukemia (t-ALL) of B cell origin is rare and constitutes approximately 2% of all ALL. Previously compiled data on the complete cytogenetic analysis of 48 t-B-ALL cases suggested that MLL rearrangement at 11q23 gene locus is the most common abnormality. Philadelphia chromosome (Ph) ...

journal_title：Pathology international

authors： Matnani R,Parekh V,Borate U,Brazelton J,Reddy V,Peker D

更新日期：2015-10-01 00:00:00

abstract：:Ovarian non-gestational choriocarcinomas co-existing with adenocarcinoma are extremely rare and have been reported as epithelial ovarian carcinomas of a "non-germ cell origin" with "choriocarcinomatous differentiation". Although the cellular origin of non-gestational choriocarcinoma may be post-meiotic ovarian germ ce...

journal_title：Pathology international

authors： Koyanagi T,Fujiwara H,Usui H,Ariga H,Machida S,Takei Y,Saga Y,Shozu M,Fukushima N,Niki T,Matsubara S,Suzuki M

更新日期：2016-09-01 00:00:00

abstract：:Twenty-eight moderately differentiated adenocarcinomas invading beyond the muscularis propria of the colorectum were subclassified as 13 moderate- and 15 poor-subtype tumors based on the histology at the deeply infiltrating sites. Moderately differentiated cancer cells were correlated with liver metastasis and p53 imm...

journal_title：Pathology international

authors： Taniyama K,Sasaki N,Wada S,Sasaki M,Miyoshi N,Nakai H,Kodama S,Nakatsuka H,Tahara E

更新日期：1996-03-01 00:00:00

abstract：:Angiomyolipoma (AML) is a mixed mesenchymal tumor belonging to the family of perivascular epithelioid cell tumors. Concurrent development of AML and adult renal cell carcinoma (RCC) is very rare. Herein is presented a unique case in which RCC arose within a previously detected AML tumor mass. A 40-year-old woman had b...

journal_title：Pathology international

authors： Inomoto C,Umemura S,Sasaki Y,Yasuda M,Terachi T,Osamura RY

更新日期：2007-03-01 00:00:00

abstract：:The findings of a 20 year old woman with lymphadenopathy that was probably caused by an acute human herpesvirus-6 (HHV-6) infection are reported. She clinically demonstrated various signs of acute infection such as a high fever, skin rash, liver dysfunction, leukocytosis, an elevation of the erythrocyte sedimentation ...

journal_title：Pathology international

authors： Sumiyoshi Y,Kikuchi M,Ohshima K,Takeshita M,Eizuru Y,Minamishima Y

更新日期：1995-12-01 00:00:00

abstract：:BAT-26 instability, a sensitive marker for the high-frequency microsatellite instability (MSI-H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI-H gastric cancer samples showed BAT-26 instability, as assessed using 12 dinucleotide microsatellite mar...

journal_title：Pathology international

authors： Jin Z,Tamura G,Satoh M,Meguro T,Miura T,Hayashi M,Osakabe M,Ohmura K,Ogata S,Endoh Y,Motoyama T

更新日期：2001-06-01 00:00:00

abstract：:The incidence of lymphoma has rapidly increased over the last 40 years in Japan, following a trend that is very similar to that of breast cancer. In particular, the relative frequency of follicular lymphoma (FL) has reached that in Western countries. Given its indolence, a "watch-and-wait" approach is often applied to...

journal_title：Pathology international

authors： Yoshino T,Takata K,Tanaka T,Sato Y,Tari A,Okada H

更新日期：2018-12-01 00:00:00

abstract：:We report a rare case of hepatocellular carcinoma (HCC) with an unusual neuroendocrine component. During a follow-up study for chronic hepatitis C in a 71-year-old man, a nodular lesion showed rapid growth from 1 cm to 4 cm in diameter within 3 months. Histologically, the tumor was consistent with moderately different...

journal_title：Pathology international

authors： Yamaguchi R,Nakashima O,Ogata T,Hanada K,Kumabe T,Kojiro M

更新日期：2004-11-01 00:00:00

abstract：:A 79-year-old man presented with back pain. Chest CT scan showed elevated nodular lesions in the right parietal pleurae with pleural effusion. There were no intrapulmonary or mediastinal abnormalities. Under local anesthesia, right thoracoscopy and subsequent thoracoscopic pleural resection were performed using an ins...

journal_title：Pathology international

authors： Kawahara K,Sasada S,Nagano T,Suzuki H,Kobayashi M,Matsui K,Takata K,Yoshino T,Michida T,Iwasaki T

更新日期：2008-04-01 00:00:00

abstract：:Secondary (metastatic) neoplasms to the ovary often cause diagnostic problems, especially those tumors that produce large, symptomatic ovarian tumors that masquerade clinically and pathologically as primary ovarian tumors of surface epithelial type. Most of these tumors arise from organs of the digestive system. Excep...

journal_title：Pathology international

authors： Hart WR

更新日期：2005-05-01 00:00:00

abstract：:A small proportion of patients with chronic lymphocytic leukemia (CLL) may progress to large cell lymphoma, or Richter syndrome (RS). The large cells of RS may arise through transformation of the original CLL clone (clonally related) or represent a new neoplasm (clonally unrelated), which might be Epstein-Barr virus (...

journal_title：Pathology international

authors： Chen YA,Wang RC,Yang Y,Chuang SS

更新日期：2016-07-01 00:00:00

abstract：:To determine the prognostic significance of the methods used to determine the presence of metastasis in second-tier lymph nodes of patients with gastric cancer, the authors studied lymph nodes surgically removed from 100 patients with gastric cancer (55 with early cancer, 45 with progressive). The results of HE staini...

journal_title：Pathology international

authors： Ikeda S,Funakoshi N,Usui S,Takiguchi N,Hiranuma S,Shibata T

更新日期：2008-01-01 00:00:00

abstract：:A case of renal adenomatosis of the left kidney associated with a carcinoma of the ipsilateral ureter in a 49-year-old man is examined. One hundred and eight adenomas, which were smaller than 15 mm in diameter, and a single microcarcinoma, which measured 1 mm in diameter, were found in the kidney. Further, there were ...

journal_title：Pathology international

authors： Kizaki T,Ugai K,Hirano H,Gohji K,Fujii A

更新日期：1999-03-01 00:00:00

abstract：:Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited cancer predisposition syndrome, characterized by development of a variety of neoplasms in multiple organs. Central nervous system hemangioblastoma (CHB) is the most common manifestation of VHL disease. The germline mutations in the VHL tumor suppressor...

journal_title：Pathology international

authors： Zhou J,Wang J,Li N,Zhang X,Zhou H,Zhang R,Ma H,Zhou X

更新日期：2010-06-01 00:00:00