Mature teratoma of the uterine cervix with lymphoid hyperplasia.

Abstract:

:A rare case of an extragonadal teratoma, which occurred primarily in the uterus, is described. The tumor developed in the uterine cervix as a conventional cervical polyp, 3 months after an elective abortion in a 27-year-old woman. Microscopically, the solid 2.2 x 1.8 x 1.5 cm mass was a mature teratoma with exuberant lymphoid elements. It consisted of ectodermal, mesodermal and endodermal derivatives. The lymphoid elements may have been a lymphoid hyperplasia, a chronic inflammatory reaction or a component of the teratoma. However, as the lymphoid tissues had no spatial relation to the teratomatous components, the possibility of a teratomatous element was excluded. This could be regarded as a result of an immunological reaction to the tissues composing the tumor, rather than just a chronic inflammatory response because the lymphoid reaction was present in the tumor, the tumor-host interface and the perivascular areas. Because of the patient's history of an abortion and a lymphoid reaction, the possibility of fetal remnants implantation was raised, so DNA typing to compare the teratoma portion with a normal portion of the host was performed. We found the teratoma portions to be in accordance with that of the host, and hence ruled out fetal remnants implantation. This case showed that a mature teratoma of the uterine cervix may manifest as a feature of implanted fetal tissue. In addition, a real teratoma should be included in the differential diagnosis of uterine teratomatous lesion, even when detected in patients with a recent history of pregnancy and lymphoid hyperplasia.

journal_name

Pathol Int

journal_title

Pathology international

authors

Lim SC,Kim YS,Lee YH,Lee MS,Lim JY

doi

10.1046/j.1440-1827.2003.01468.x

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

327-31

issue

5

eissn

1320-5463

issn

1440-1827

pii

1468

journal_volume

53

pub_type

杂志文章
  • Desmoplastic reaction in biopsy specimens of early colorectal cancer: a Japanese prospective multicenter study.

    abstract::We previously reported that detection of desmoplastic reaction (DR) in pretreatment biopsy specimens was useful for predicting the depth of submucosal invasion (SM depth) in nonpedunculated early colorectal cancers (ECRCs) in a retrospective study. Here, we performed a prospective multicenter study for verification of...

    journal_title:Pathology international

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1440-1827.2012.02840.x

    authors: Kimura R,Fujimori T,Ichikawa K,Ajioka Y,Ueno H,Ohkura Y,Kashida H,Togashi K,Yao T,Wada R,Watanabe T,Ochiai A,Sugai T,Sugihara K,Igarashi Y

    更新日期:2012-08-01 00:00:00

  • Bile duct adenoma and von Meyenburg complex-like duct arising in hepatitis and cirrhosis: pathogenesis and histological characteristics.

    abstract::Morphologic features and neoplastic potentials of bile duct adenoma (BDA) and von Meyenburg complex (VMC)-like duct arising in chronic liver disease were unknown. Thirty-five BDAs and 12 VMC-like duct lesions were observed in 39 cases with chronic liver disease. BDAs were divided into the EMA-cytoplasmic type (n = 14)...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12209

    authors: Aishima S,Tanaka Y,Kubo Y,Shirabe K,Maehara Y,Oda Y

    更新日期:2014-11-01 00:00:00

  • Critical multi-organ emboli originating from collapsed, vulnerable caseous mitral annular calcification.

    abstract::Mitral annular calcification (MAC) is a generally asymptomatic abnormality found commonly in aged hearts. Some clinical studies have suggested that MAC should be considered an independent risk factor for stroke; however, whether the abnormality is indeed a risk factor remains controversial. We report a case in which d...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2012.02826.x

    authors: Matsuyama TA,Ishibashi-Ueda H,Ikeda Y,Nagatsuka K,Miyashita K,Amaki M,Kanzaki H,Kitakaze M

    更新日期:2012-07-01 00:00:00

  • Recommendations for the reporting of resected prostate carcinomas. Association of Directors of Anatomic and Surgical Pathology Agency.

    abstract::The Association of Directors of Anatomic and Surgical Pathology has developed recommendations for the surgical reporting of common malignant tumors. The recommendations for prostatic carcinoma are reported herein. ...

    journal_title:Pathology international

    pub_type: 指南,杂志文章

    doi:10.1111/j.1440-1827.1997.tb04491.x

    authors:

    更新日期:1997-04-01 00:00:00

  • Whole-slide imaging at primary pathological diagnosis: Validation of whole-slide imaging-based primary pathological diagnosis at twelve Japanese academic institutes.

    abstract::Several reports have demonstrated the use of whole-slide imaging (WSI) for primary pathological diagnosis, but no such studies have been published from Asia. We retrospectively collected 1070 WSI specimens from 900 biopsies and small surgeries conducted in nine hospitals. Nine pathologists, who participated in this st...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12590

    authors: Tabata K,Mori I,Sasaki T,Itoh T,Shiraishi T,Yoshimi N,Maeda I,Harada O,Taniyama K,Taniyama D,Watanabe M,Mikami Y,Sato S,Kashima Y,Fujimura S,Fukuoka J

    更新日期:2017-11-01 00:00:00

  • Presence of natural killer-cell clones with variable proliferative capacity in chronic active Epstein-Barr virus infection.

    abstract::Chronic active Epstein-Barr virus infection (CAEBV) is a syndrome that takes diverse clinical courses and is often associated with lymphoproliferative disorders of T/natural killer (NK)-cell lineage. We describe a patient with CAEBV associated with persistent pharyngeal ulcer, and with subsequent nasal T/NK-cell lymph...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2001.01276.x

    authors: Nagata H,Numata T,Konno A,Mikata I,Kurasawa K,Hara S,Nishimura M,Yamamoto K,Shimizu N

    更新日期:2001-10-01 00:00:00

  • Molecular analysis of isolated tumor glands from endometrial endometrioid adenocarcinomas.

    abstract::We studied the extensive molecular alterations of endometrial endometrioid adenocarcinoma (EEA) using a crypt isolation method. We analyzed copy number variation (CNV) using a single nucleotide polymorphism (SNP) array, genetic mutations (KRAS, BRAF, p53, PIK3CA), DNA methylation and microsatellite instability (MSI) s...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12274

    authors: Suga Y,Sugai T,Uesugi N,Kawasaki T,Fukagawa T,Yamamoto E,Ishida K,Suzuki H,Sugiyama T

    更新日期:2015-05-01 00:00:00

  • A morphometric study to establish criteria for fetal and neonatal cerebellar hypoplasia: A special emphasis on trisomy 18.

    abstract::Cerebellar hypoplasia (CH) is one of the congenital abnormalities of the central nervous system and is seen in several diseases and syndromes. This study was conducted in order to examine methods for evaluating CH in fetus and neonate because CH has been diagnosed without any morphometric criteria at autopsy. We sampl...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12371

    authors: Murakami A,Tanaka M,Ijiri R,Kato K,Yamashita S,Kurosawa K,Arai N,Aoki I,Tanaka Y

    更新日期:2016-01-01 00:00:00

  • Expression of bcl-6 protein in normal skin and epidermal neoplasms.

    abstract::Bcl-6 protein is a recently identified novel transcription factor whose deregulated expression is associated with diffuse large B cell lymphomas. It was recently shown by us that the protein is located in germinal center B cells and their neoplastic counterparts. In the present study, the expression of bcl-6 protein o...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1997.tb04548.x

    authors: Kanazawa N,Moriyama M,Onizuka T,Sugawara K,Mori S

    更新日期:1997-09-01 00:00:00

  • Inflammatory pseudotumor of the liver in a patient with chronic hepatitis C: difficulty in differentiating it from hepatocellular carcinoma.

    abstract::A case of an inflammatory pseudotumor of the liver in a 75-year-old female with chronic hepatitis C whose radiologic features simulated that of hepatocellular carcinoma (HCC) is presented. On imaging studies, hypervascularity by CO2 ultrasound (US) angiography, enhancement at an early phase and isodensity at a late ph...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.1999.00927.x

    authors: Kim SR,Hayashi Y,Kudo M,Matsuoka T,Imoto S,Sasaki K,Shintani S,Song KB,Park SY,Kim JH,Ando K,Koterazawa T,Kim KI,Ninomiya T

    更新日期:1999-08-01 00:00:00

  • Expression of p73 in normal skin and proliferative skin lesions.

    abstract::The p73 gene is a member of the p53 gene family and the structure and functions of p73 protein are similar to those of p53. However, these two proteins have different roles. In the present study, p73 protein was found immunohistochemically to be distributed in the basal cells of the epidermis, columnar basal cells in ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2004.01777.x

    authors: Kamiya M,Takeuchi Y,Katho M,Yokoo H,Sasaki A,Nakazato Y

    更新日期:2004-12-01 00:00:00

  • Primary leiomyosarcoma of the vertebra: Case report and review of the literature.

    abstract::A case of primary leiomyosarcoma of a thoracic vertebra associated with a compression fracture in a 75-year-old woman was preoperatively thought to be granulation tissue. Surgical decompression was performed and the histological and immunohistochemical studies established the diagnosis of leiomyosarcoma. Based on the ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2004.01582.x

    authors: Sasaguri T,Tanimoto A,Kimura S,Kohno Y,Hirasawa M,Matsuki Y,Abe K,Hashimoto H,Hamada T,Sasaguri Y

    更新日期:2004-01-01 00:00:00

  • Duct-acinar-islet cell tumor of the pancreas.

    abstract::A case of a rare pancreatic tumor, duct-acinar-islet cell tumor is presented. The tumor was incidentally found in the pancreatic body on computed tomography of a 21 year old male suffering from mumps. It was well demarcated from surrounding pancreas, and spherical in shape, measured 2.5 cm in diameter. Histologic and ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1995.tb03520.x

    authors: Okada Y,Mori H,Tsutsumi A

    更新日期:1995-09-01 00:00:00

  • Human papillomavirus infection in Egyptian esophageal carcinoma: correlation with p53, p21, mdm2, C-erbB2 and impact on survival.

    abstract::The etiological role of human papillomavirus (HPV) in esophageal carcinoma (EC) in relation to p53, mdm2, p21(waf), c-erbB2 and the overall survival (OS) rate was investigated. Tumor and normal tissues from 50 EC were evaluated by polymerase chain reaction and InnoLiPA for HPV. Single strand conformation polymorphism/...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2005.01804.x

    authors: Bahnassy AA,Zekri AR,Abdallah S,El-Shehaby AM,Sherif GM

    更新日期:2005-02-01 00:00:00

  • Expression of double-stranded RNA-activated protein kinase in small-size peripheral adenocarcinoma of the lung.

    abstract::The authors investigated the protein expression of double-stranded RNA-activated protein kinase (PKR), which was identified by using a previous cDNA microarray study, to discover PKR's correlations with several pathological parameters and to elucidate its role in neoplastic transformation and progression of lung adeno...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2005.01892.x

    authors: Roh MS,Kwak JY,Kim SJ,Lee HW,Kwon HC,Hwang TH,Choi PJ,Hong YS

    更新日期:2005-11-01 00:00:00

  • Metastatic pineocytoma of the spinal cord after long-term dormancy.

    abstract::An unusual tumor in the spinal cord of a 57 year old man is reported. At the age of 42 years, the patient had had a pineal region tumor that subsequently disappeared completely after local radiation therapy only. Eleven and 15 years later, at the ages of 53 and 57 years, respectively, solitary spinal cord tumors were ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1994.tb01685.x

    authors: Ito T,Takahashi H,Ikuta F,Sato H

    更新日期:1994-12-01 00:00:00

  • Long-term observation of glomerulonephritis induced by multiple injections with anti-Thy-1 antibody in rats.

    abstract::Multiple injections with a mouse monoclonal anti-rat Thy-1 antibody (five times, at weekly intervals) induced marked glomerular sclerotic lesions which are characterized by adhesion of glomerular capillaries to Bowman's capsule and persistent proteinuria in rats. Abnormal production of type I collagen and increased ac...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1998.tb03939.x

    authors: Yagi M,Yamamoto T,Kato S,Nagano N,Kihara I

    更新日期:1998-07-01 00:00:00

  • Less aggressive features of colorectal cancer with liver metastases showing macroscopic intrabiliary extension.

    abstract::We have previously reported the frequent occurrence of bile duct invasion by liver metastases from colorectal cancer. We found that patients with macroscopic intrabiliary cancer growth survive longer after hepatectomy than those without this feature. In the present study, we analyzed the clinicopathological features o...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2002.01382.x

    authors: Kubo M,Sakamoto M,Fukushima N,Yachida S,Nakanishi Y,Shimoda T,Yamamoto J,Moriya Y,Hirohashi S

    更新日期:2002-08-01 00:00:00

  • Evolution, controversies and the future of prostate cancer grading.

    abstract::Histological grading of prostate cancer is one of the most important tissue-based parameters for prediction of outcome and treatment response. Gleason grading remains the foundation of prostate cancer grading, but has undergone a series of changes in the past 30 years, often initiated by consensus conference decisions...

    journal_title:Pathology international

    pub_type: 杂志文章,评审

    doi:10.1111/pin.12761

    authors: Egevad L,Delahunt B,Yaxley J,Samaratunga H

    更新日期:2019-02-01 00:00:00

  • Numerous eosinophilic globules (skeinoid fibers) in a duodenal stromal tumor: an exceptional case showing smooth muscle differentiation.

    abstract::A unique case of duodenal stromal tumor in a 51-year-old man is reported. The tumor histologically showed spindle cell proliferation and numerous eosinophilic globules. Most globules were composed of tangled 45 nm thick fibrils, which were ultrastructurally identical to 'skeinoid fibers'. The presence of glycogen gran...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1997.tb04459.x

    authors: Matsukuma S,Doi M,Suzuki M,Ikegawa K,Sato K,Kuwabara N

    更新日期:1997-11-01 00:00:00

  • Three synchronous carcinomas of the papilla of Vater, common bile duct and pancreas.

    abstract::Multiple carcinomas of the pancreatico-biliary tree are rare. A 53 year old Japanese man was diagnosed as having an adenocarcinoma in the papilla of Vater. During the operation, he was also found to have a polypoid mass in the common bile duct. While cutting the operative specimen into stepwise sections, a small tumor...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1994.tb03371.x

    authors: Nishihara K,Tsuneyoshi M,Shimura H,Yasunami Y

    更新日期:1994-04-01 00:00:00

  • Abnormalities in chromosome 17 and p53 in lung carcinoma cells detected by fluorescence in situ hybridization.

    abstract::The value of fluorescence in situ hybridization (FISH) as an aid to deciding the prognosis for lung carcinoma patients, comparing quantitatively the signal from the p53 gene (17p13.1) on chromosome 17, was studied. A dual-labeling technique was used, using probes for the centromeric region of chromosome 17 and for the...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2004.01635.x

    authors: Kawai T,Hiroi S,Nakanishi K,Sakurai Y,Torikata C

    更新日期:2004-06-01 00:00:00

  • Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible.

    abstract::Three cell systems (MINT1/2/3) derived from a melanotic neuroectodermal tumor of infancy (MNTI) arising in the mandible of a 1-month-old newborn boy have been established, and their cytological natures have been characterized. The cells had immunopositivities for pan-keratin, vimentin, neuron-specific enolase, S-100 p...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2005.01833.x

    authors: Metwaly H,Cheng J,Maruyama S,Ohshiro K,Suzuki I,Hoshina Y,Saku T

    更新日期:2005-06-01 00:00:00

  • Immunoexpression of the alpha subunit of a guanine nucleotide-binding protein (Go) in pulmonary neuroendocrine cells and neoplasms.

    abstract::The alpha subunit of a GTP-binding protein, Go, was investigated in pulmonary neuroendocrine neoplasms and fetal tissues of the lung by an immunohistochemical method. Positive immunostaining for the alpha subunit of Go (Go alpha) was found predominantly on the cell membrane and found occasionally in the cytoplasm. Typ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1996.tb03629.x

    authors: Kawano N,Ito T,Kitamura H,Shibagaki T,Kameda Y,Nakamura N,Kanisawa M

    更新日期:1996-06-01 00:00:00

  • An immunohistochemical and genetic study of BRAFV600E mutation in Japanese patients with ameloblastoma.

    abstract::Ameloblastoma is an odontogenic tumor of the jaw. It most frequently occurs in the mandible, and less often in the maxilla. Mandibular ameloblastoma harbors a BRAF mutation that causes a valine (V) to glutamic acid (E) substitution at codon 600 (BRAFV600E ). We examined specimens from 32 Japanese patients to detect th...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12899

    authors: Seki-Soda M,Sano T,Ito K,Yokoo S,Oyama T

    更新日期:2020-04-01 00:00:00

  • A rare case of pulmonary typical carcinoid with prominent acinic cell differentiation, resembling acinic cell carcinoma.

    abstract::We herein describe a rare case of low-grade endobronchial tumor that exhibited two distinct features of typical carcinoid and acinic cell carcinoma (ACC) by immunohistochemical and ultrastructure study. ACC was suspected on transbronchial biopsy. The resected specimen showed that the tumor surface comprised an acinic ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/pin.12869

    authors: Watanabe H,Miyagawa-Hayashino A,Imabayashi T,Kishimoto M,Shimomura M,Honda K,Omatsu I,Shimada E,Inoue M,Takayama K,Konishi E

    更新日期:2019-12-01 00:00:00

  • Clinicopathological significance of invasive micropapillary carcinoma component in invasive breast carcinoma.

    abstract::Invasive micropapillary carcinoma (IMP) of the breast is a rare variant of invasive breast carcinoma and most cases of IMP are associated with nodal metastasis and lymphatic invasion. Lesions composed of an IMP component alone are rare and almost always coexist with other pathological components. However, few reports ...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.2011.02735.x

    authors: Ide Y,Horii R,Osako T,Ogura K,Yoshida R,Iwase T,Akiyama F

    更新日期:2011-12-01 00:00:00

  • Transferrin receptor distribution and iron deposition in the hepatic lobule of iron-overloaded rats.

    abstract::Under the condition of obvious iron-overload, there is a zonal hemosiderin (iron) deposition in hepatic lobules. The deposition is heaviest in the periportal (zone 1) and lightest in the perivenous (zone 3) hepatocytes. However, the mechanism for this pattern of iron deposition is obscure. Hepatic tissues from control...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1995.tb03443.x

    authors: Lu JP,Hayashi K

    更新日期:1995-03-01 00:00:00

  • Small cell carcinoma arising from the outer urethral orifice: a case report examined by histologic, ultrastructural and immunohistochemical methods.

    abstract::A case of small cell carcinoma arising in the outer urethral orifice is presented. The resected tumor showed a proliferation of small round or fusiform neoplastic cells in the submucosa. Tumor cells were arranged in sheets or a trabecular manner and possessed markedly hyperchromatic nuclei with a high N:C ratio, close...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1111/j.1440-1827.1997.tb04530.x

    authors: Fukuda T,Kamishima T,Saito T,Itoh S,Suzuki T

    更新日期:1997-07-01 00:00:00

  • Sebaceous carcinoma of the breast.

    abstract::We report on a rare distinctive variant of infiltrating ductal carcinoma characterized by sebaceous differentiation of tumor cells. The neoplasm was identified in a lumpectomy specimen from a 45-year-old woman with extensive metastatic disease. In addition to conventional in situ and invasive ductal components, approx...

    journal_title:Pathology international

    pub_type: 杂志文章

    doi:10.1046/j.1440-1827.2000.01003.x

    authors: Varga Z,Kolb SA,Flury R,Burkhard R,Caduff R

    更新日期:2000-01-01 00:00:00