A morphometric study to establish criteria for fetal and neonatal cerebellar hypoplasia: A special emphasis on trisomy 18.

abstract：:Soluble receptor-resistant mutant 7 (ssr7) is isolated from a highly neurovirulent mouse hepatitis virus (MHV) JHMV cl-2 strain (cl-2). srr7 exhibits lower virulence than its maternal strain in infected mice, which is typically manifested in a longer lifespan. In this study, during the course of infection with srr7, s...

journal_title：Pathology international

authors： Kashiwazaki H,Nomura R,Matsuyama S,Taguchi F,Watanabe R

更新日期：2011-04-01 00:00:00

abstract：:A 35-year-old Japanese man who had experienced hoarseness for 10 years presented with a vocal cord lesion. A gross examination revealed a left vocal cord polyp occupying two-thirds of the vocal space. The endoscopically resected lesion contained scattered atypical fibroblastic, stellate, or ganglion-like cells with mu...

journal_title：Pathology international

authors： Yorita K,Togashi Y,Nakagawa H,Miyazaki K,Sakata S,Baba S,Takeuchi K,Hayashi Y,Murakami I,Kuroda N,Oda Y,Kohashi K,Yamada Y,Kiyozawa D,Michal M,Michal M

更新日期：2019-06-01 00:00:00

abstract：:A very rare case of a double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver in a 65-year-old-man is discussed. The patient was hospitalized with epigastralgia in May 1997. Abdominal computed axial tomography revealed a tumor located in the left lobe of the liver and a left hepatic lobect...

journal_title：Pathology international

authors： Zhang Z,Nonaka H,Nagayama T,Hatori T,Ihara F,Zhang L,Akima M,Shiba T

更新日期：2001-12-01 00:00:00

abstract：:A rare case of an extragonadal teratoma, which occurred primarily in the uterus, is described. The tumor developed in the uterine cervix as a conventional cervical polyp, 3 months after an elective abortion in a 27-year-old woman. Microscopically, the solid 2.2 x 1.8 x 1.5 cm mass was a mature teratoma with exuberant ...

journal_title：Pathology international

authors： Lim SC,Kim YS,Lee YH,Lee MS,Lim JY

更新日期：2003-05-01 00:00:00

abstract：:An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells thr...

journal_title：Pathology international

authors： Motosugi U,Ichikawa T,Yamaguchi H,Nakazawa T,Katoh R,Itakura J,Fujii H,Sato T,Araki T,Shimizu M

更新日期：2009-10-01 00:00:00

abstract：:We investigated the diagnostic and prognostic value of p53 expression and proliferative activity, as indicated by the Ki-67, in endoscopic biopsy specimens. Specimens were immunologically stained with p53 and MIB-1 (Ki-67), and the MIB-1/Ki-67 labeling index (LI) was calculated. Classification of adenomas was based on...

journal_title：Pathology international

authors： Kubota K,Kakuta Y,Kawamura S,Saito S,Seki H,Kuniyoshi T

更新日期：2003-06-01 00:00:00

abstract：:An electron microscopic study of peripheral leukocytes obtained from a 39 year old woman with Hermansky-Pudlak syndrome was performed. Ceroid pigment granules were found within the lysosomes in 3.5% of monocytes and 5.4% of lymphocytes. Infrequently, pigment granules were also found in the parallel tubular arrays of l...

journal_title：Pathology international

authors： Sakuma T,Monma N,Satodate R,Satoh T,Takeda R,Kuriya S

更新日期：1995-11-01 00:00:00

abstract：:Circulating leukocytes, particularly neutrophils and monocytes, are important effector cells in the induction of many forms of glomerulonephritis. Adhesion molecules, especially selectins, are also thought to be critical for the development of this disease. We examined the possible suppressive effect of soluble E-sele...

journal_title：Pathology international

authors： Takahashi S,Araki K,Araki M,Ito MR,Nakatani K,Fujii H,Izui S,Vassalli P,Nose M

更新日期：2002-03-01 00:00:00

abstract：:The morphological expression of the immune response of palatine tonsils obtained from patients with pustulosis palmaris et plantaris (PPP) was investigated by morphometry in conjunction with immunohistochemistry. First, to differentiate the histological features of tonsils between PPP and habitual tonsillitis, each ex...

journal_title：Pathology international

authors： Sakai T,Kawaguchi M,Ishizawa S,Kaji T,Kitagawa K,Koizumi F

更新日期：1994-03-01 00:00:00

abstract：:The diagnosis of the rare neoplasm histiocytic sarcoma (HS) relies on morphology and the presence of immunophenotypic features of histiocytic lineage. More than 57 cases, including 16 cases involving the gastrointestinal (GI) tract, have been described since the World Health Organization issued its classification syst...

journal_title：Pathology international

authors： Miyazaki T,Arihiro S,Mitobe J,Aoki Y,Takikawa S,Saruta M,Matsuoka M,Koike K,Kato T,Kashiwagi H,Ikegami M,Tajiri H

更新日期：2013-02-01 00:00:00

abstract：:A complete spontaneous regression of diffuse large B cell lymphoma involving the right breast, confirmed by aspiration cytology, is reported. The patient visited a hospital due to the rapid growth of a tumor in the right breast. Five years previously she underwent a craniotomy for a brain tumor, diagnosed as B-cell ma...

journal_title：Pathology international

authors： Iihara K,Yamaguchi K,Nishimura Y,Iwasaki T,Suzuki K,Hirabayashi Y

更新日期：2004-07-01 00:00:00

abstract：:A pulmonary Langerhans cell histiocytosis is presented in a 40 year-old woman two years after bilateral lung transplantation for emphysema without any signs of Langerhans cells proliferation in the explanted lungs. A microsatellite molecular analysis showed the proliferating cells were generated in a recipient cellula...

journal_title：Pathology international

authors： Gómez-Román J,Zarrabeitia MT,Santurtún A,Parra JA,Azueta Etxebarría A,Cifrian JM,Freire Salinas J

更新日期：2017-12-01 00:00:00

abstract：:BRN2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. We investigated the importance of BRN2 in the expression of the lineage-specific transcription factors (achaete-scute homolog-like 1 (ASCL1) and NeuroD1 (ND1)) and neural/neuroendocrine marker mo...

journal_title：Pathology international

authors： Ishii J,Sato H,Sakaeda M,Shishido-Hara Y,Hiramatsu C,Kamma H,Shimoyamada H,Fujiwara M,Endo T,Aoki I,Yazawa T

更新日期：2013-03-01 00:00:00

abstract：:Pituicytoma is a rare low-grade glial neoplasm that originates in the neurohypophysis or infundibulum. Because of its rare occurrence, the morphology and differentiation of pituicytoma have not been fully clarified. Here, we report a case of pituicytoma with unusual histological features mimicking ependymoma, but exhi...

journal_title：Pathology international

authors： Kwon MJ,Suh YL

更新日期：2011-10-01 00:00:00

abstract：:We report a case of ALK-positive renal cell carcinoma coincident with Hodgkin lymphoma. The patient was a 19 year-old-girl without sickle cell trait. The right renal tumor was discovered concomitantly with Hodgkin lymphoma (HL). After chemotherapy for HL, right nephrectomy was performed. Microscopically, the tumor sho...

journal_title：Pathology international

authors： Oyama Y,Nishida H,Kusaba T,Kadowaki H,Arakane M,Daa T,Watanabe D,Akita Y,Sato F,Mimata H,Yokoyama S

更新日期：2017-12-01 00:00:00

abstract：:The chemokine receptor CXCR4 belongs to the large superfamily of G protein-coupled receptors and has been identified to play a crucial role in a number of biological processes, including the trafficking and homeostasis of immune cells such as T lymphocytes. CXCR4 has also been found to be a prognostic marker in variou...

journal_title：Pathology international

authors： Furusato B,Mohamed A,Uhlén M,Rhim JS

更新日期：2010-07-01 00:00:00

abstract：:An extremely rare case of unilateral gonadoblastoma with mixed germ cell tumor arising in the ovary of a 27-year-old woman with 46,XX karyotype and two successful pregnancies is reported. The mixed germ cell tumor was composed of choriocarcinoma, embryonal carcinoma, yolk sac tumor, immature teratoma and dysgerminoma....

journal_title：Pathology international

authors： Zhao S,Kato N,Endoh Y,Jin Z,Ajioka Y,Motoyama T

更新日期：2000-04-01 00:00:00

abstract：:Metallothionein (MT) has been reported to play important physiological roles in the human body, but the distribution and significance of MT is not fully understood. In order to analyze MT expression, three kinds of polyclonal MT fragment antibodies were developed against NH2-terminal, middle regional and COOH-terminal...

journal_title：Pathology international

authors： Nakazato K,Nakajima K,Kusakabe T,Suzuki K,Nagamine T

更新日期：2008-12-01 00:00:00

abstract：:Giant cell tumor (GCT) of bone is a primary osteolytic tumor that is characterized by the formation of osteoclast-like giant cells. In addition to GCT of bone, extraskeletal GCT are known to be formed in several soft tissues. Giant cells in GCT of bone were suggested to be identical to osteoclasts, but the characteriz...

journal_title：Pathology international

authors： Ikeda T,Seki S,Maki M,Noguchi N,Kawamura T,Arii S,Igari T,Koike M,Hirokawa K

更新日期：2003-07-01 00:00:00

abstract：:Esophageal squamous cell carcinoma in situ (SCCIS) with diffuse pagetoid features is a recently recognized rare variant of squamous cell carcinoma. A histopathological study of a specimen from a 70-year-old male Japanese patient is reported. The patient died of respiratory failure due to rapidly progressing metastatic...

journal_title：Pathology international

authors： Ishihara A,Mori T,Koono M

更新日期：2002-02-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVGC) is defined as a neoplasm comprising monoclonal proliferation of EBV-infected gastric epithelial cells. Although the typical histology is gastric carcinoma with lymphoid stroma (GCLS), the histologic features of the tumor vary. We report herein the case of a...

journal_title：Pathology international

authors： Shimizu A,Takahashi T,Kushima R,Sentani K,Yasui W,Matsuno Y

更新日期：2018-01-01 00:00:00

abstract：:Patients with pulmonary small cell carcinoma are well known to have a poor prognosis. However, predictors of prognosis and treatment outcome have not been reported for this type of cancer. We examined whether excision repair cross-complementation group 1 (ERCC1), phosphorylated Akt (p-Akt), phosphorylated mammalian ta...

journal_title：Pathology international

authors： Ikeda S,Takabe K,Inagaki M,Suzuki K

更新日期：2010-11-01 00:00:00

abstract：:The Association of Directors of Anatomic and Surgical Pathology has developed recommendations for the surgical reporting of common malignant tumors. The recommendations for prostatic carcinoma are reported herein. ...

journal_title：Pathology international

authors：

更新日期：1997-04-01 00:00:00

abstract：:Many reports have suggested a strong correlation between certain lectin-binding patterns and biological behavior in various tumors. To clarify a relationship between lectin-binding reactivity and survival of patients with diffuse large B-cell lymphoma (B-DLCL), 57 cases with B-DLCL were analyzed by lectin histochemist...

journal_title：Pathology international

authors： Suzuki O,Nozawa Y,Kawaguchi T,Abe M

更新日期：1999-10-01 00:00:00

abstract：:Actinic cheilitis (AC) is an early keratocyte neoplasia with inflammation that occurs in the lip vermillion with the potential to develop into invasive squamous cell carcinoma (SCC). The expression of the intracellular enzyme indoleamine 2,3-dioxygenase (IDO) by antigen-presenting cells and/or tumor cells has been des...

journal_title：Pathology international

authors： von Bubnoff D,Zahn S,Wenzel J,Wilms H,Bieber T,Lüftl M

更新日期：2012-02-01 00:00:00

abstract：:In papillary thyroid carcinoma (PTC) in cytological and surgical specimens, fine chromatin, nuclear grooves and nuclear pseudoinclusions are the hallmarks of diagnosis. We investigated the significance of these nuclear changes in neoplastic non-PTC lesions. Fine needle aspiration biopsies (FNAB) of thyroid lesions wer...

journal_title：Pathology international

authors： Mai KT,Yazdi HM,Commons AS,Perkins DG,MacDonald L

更新日期：1999-07-01 00:00:00

abstract：:Microscopic pulmonary tumor embolism is difficult to diagnose. Herein is presented the case of a patient who suffered from acute dyspnea and breast cancer on the right side. Two weeks after the breast cancer diagnosis the patient began to experience dyspnea. After 2 weeks of dyspnea, the patient died without an accura...

journal_title：Pathology international

authors： Kawasaki H,Ogura H,Arai Y,Baba S,Kosugi I,Tsutsui Y,Iwashita T

更新日期：2010-03-01 00:00:00

abstract：:The CDKN2 gene encodes two structurally different proteins: a cyclin-dependent kinase inhibitor, p16, which regulates retinoblastoma protein (pRb)-dependent G1 arrest, and a cell cycle inhibitor, p14ARF, which blocks MDM2-induced p53 degradation resulting in an increase in p53 levels that leads to cell cycle arrest. R...

journal_title：Pathology international

authors： Sano T,Masuda N,Oyama T,Nakajima T

更新日期：2002-05-01 00:00:00

abstract：:A report of a 65-year-old male with a tumor arising from synovial tissue of the radio-ulnar joint. On magnetic resonance imaging, the tumor was demonstrated as a heterogeneous and lobulated mass with a low signal intensity both in T1- and T2-weighted images. Histological findings of the tumor were identical to those o...

journal_title：Pathology international

authors： Misawa A,Okada K,Hirano Y,Sageshima M

更新日期：1999-12-01 00:00:00

abstract：:Breast cancer patients have a generally increased risk of developing second cancers. The object of this study was to clarify the increased as well as decreased incidence of cancers in breast cancer patients using autopsy cases. 164 211 autopsy cases in the Annual of Pathological Autopsy Cases in Japan from 2002 to 201...

journal_title：Pathology international

authors： Shibahara Y,Sugawara Y,Miki Y,Hata S,Takahashi H,Nakamura Y,Suzuki T,Ohuchi N,Tsuji I,Sasano H

更新日期：2016-12-01 00:00:00