A case of anaplastic lymphoma kinase-positive renal cell carcinoma coincident with Hodgkin lymphoma.

abstract：:Aerobes, including humans, are consistently exposed to oxidative stress by consuming oxygen. The biological significance of oxidative stress via reactive oxygen and nitrogen species consists of two stages: reversible redox regulation and irreversible oxidative molecular damage, which are sometimes intermingled. During...

journal_title：Pathology international

authors： Toyokuni S,Akatsuka S

更新日期：2007-08-01 00:00:00

abstract：:We recently established a high-speed, label-free, spectral imaging method based on stimulated Raman scattering (SRS). This method enables examination of cellular features within relatively short periods, thus enabling new imaging applications in pathology. Previously, we reported on label-free visualization of mouse t...

journal_title：Pathology international

authors： Satoh S,Otsuka Y,Ozeki Y,Itoh K,Hashiguchi A,Yamazaki K,Hashimoto H,Sakamoto M

更新日期：2014-10-01 00:00:00

abstract：:Cerebellar hypoplasia (CH) is one of the congenital abnormalities of the central nervous system and is seen in several diseases and syndromes. This study was conducted in order to examine methods for evaluating CH in fetus and neonate because CH has been diagnosed without any morphometric criteria at autopsy. We sampl...

journal_title：Pathology international

authors： Murakami A,Tanaka M,Ijiri R,Kato K,Yamashita S,Kurosawa K,Arai N,Aoki I,Tanaka Y

更新日期：2016-01-01 00:00:00

abstract：:We report a case of cutaneous squamous cell carcinoma (CSCC), initially coexisting with invasive extramammary Paget's disease (EMPD), in the scrotum of an 84-year-old man. The patient initially had a rash and pruritus before presenting with a pedunculated scrotal mass surrounded by widespread erythema. He underwent to...

journal_title：Pathology international

authors： Kitano A,Izumi M,Tamura K,Tonegawa M,Etou T,Kishida Y

更新日期：2019-10-01 00:00:00

abstract：:Tumor suppressor in lung cancer-1 (TSLC1) is an intercellular adhesion molecule of the immunoglobulin superfamily. There is little information regarding the developmental expression profiles. In an attempt to clarify the distribution of TSLC1 proteins in mouse embryos tissue by immunohistochemistry, it was found that ...

journal_title：Pathology international

authors： Usami Y,Ito A,Ohnuma K,Fuku T,Komori T,Yokozaki H

更新日期：2007-02-01 00:00:00

abstract：:We elucidated clinicopathological characteristics of chondroblastoma (CB) in Japan, and reliable clinicopathologic parameters predicting local recurrence and/or metastasis. Clinicopathological profiles of 103 CB (80 male, 23 female) in extra-craniofacial bones were retrieved. Numerical scoring of nine pathological and...

journal_title：Pathology international

authors： Konishi E,Nakashima Y,Mano M,Tomita Y,Kubo T,Araki N,Morii E,Yoshikawa H,Haga H,Toguchida J,Ueda T,Osawa M,Hoshi M,Inoue T,Aono M,Yanagisawa A

更新日期：2017-10-01 00:00:00

abstract：:Presented is the first Japanese case of ossifying renal tumor of infancy (ORTI), which is an extremely rare tumor and of which only nine cases have been reported in the literature. The patient was a four-month-old Japanese boy presenting as hematuria. A small nodular tumor (approximately 1 cm in size) protruded into t...

journal_title：Pathology international

authors： Ito J,Shinohara N,Koyanagi T,Hanioka K

更新日期：1998-02-01 00:00:00

abstract：:Autosomal recessive polycystic kidney disease (ARPKD) is caused by genetic mutations of the gene encoding fibrocystin, and is characterized by the collecting duct cysts and congenital hepatic fibrosis. We report an autopsy-proven case of ARPKD in a 77-year-old male who presented with rapidly progressive renal and live...

journal_title：Pathology international

authors： Taneda S,Honda K,Aoki A,Nitta K,Tamura T,Yoshioka Y,Oda H

更新日期：2012-12-01 00:00:00

abstract：:Bronchiolitis obliterans (BO) is generally believed to be a marker of pulmonary manifestation of graft-versus-host disease (GVHD) in patients who have undergone bone marrow transplantation for hematological malignancy. Pulmonary manifestations reported as GVHD (other than BO) include lymphocytic bronchiolitis with cel...

journal_title：Pathology international

authors： Miyagawa-Hayashino A,Sonobe M,Kubo T,Yoshizawa A,Date H,Manabe T

更新日期：2010-02-01 00:00:00

abstract：:Diffuse pulmonary ossification (DPO) is a rare condition characterized by diffuse metaplastic bone formation in the lungs. Two patterns have been described: dendriform, with a coral-like network of bone spiculae along the alveolar septa; and nodular, with lobulated fragments in the alveolar spaces. Dendriform DPO is f...

journal_title：Pathology international

authors： Porzionato A,Macchi V,Da Broi U,Giraudo C,Miotto D,Rodriguez D,Moreschi C,De Caro R

更新日期：2015-01-01 00:00:00

abstract：:Interactions among p53, bcl-2 and Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in nasopharyngeal carcinoma (NPC) cells were evaluated by gene cotransfections. The data showed that bcl-2 expression was not only able to prevent the growth suppression induced by wild-type p53 but was also paradoxically able ...

journal_title：Pathology international

authors： Sheu LF,Chen A,Lee HS,Hsu HY,Yu DS

更新日期：2004-07-01 00:00:00

abstract：:Seven cases of primary amyloidosis (AL-type) were studied immunocytochemically for the possible involvement of pancreatic islets. The two cases with extensive organ involvement by AL-amyloidosis revealed amyloid deposits in pancreatic islets by routine HE and Congo red staining, which were positive for amyloid p and a...

journal_title：Pathology international

authors： Tomita T

更新日期：2005-04-01 00:00:00

abstract：:CpG island methylator phenotype (CIMP) is a recently described subset of colorectal cancers (CRC) with widespread methylation of multiple promoter CpG islands. But the prognostic implication of CIMP in CRC has not been clarified. Thus, the aim of the present study was to differentiate the unique characteristics of CIM...

journal_title：Pathology international

authors： Lee S,Cho NY,Choi M,Yoo EJ,Kim JH,Kang GH

更新日期：2008-02-01 00:00:00

abstract：:An autopsy case of an 18 month old male infant with measles infection is reported. An autopsy revealed generalized lymphadenopathy, splenomegaly and hyperplastic thymus. Histologically, there were many Warthin-Finkeldey cells (WFC) in hyperplastic lymphoid tissues. Although viral particles and inclusions were not dete...

journal_title：Pathology international

authors： Nozawa Y,Ono N,Abe M,Sakuma H,Wakasa H

更新日期：1994-06-01 00:00:00

abstract：:We present a case of uterine intravenous leiomyomatosis associated with multiple pulmonary metastases with bullae-like cystic change. A 53-year-old woman who had undergone hysterectomy 5 years previously underwent an operation for multiple pulmonary nodules with bullae formation. After resection of several large bulla...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T,Hisayoshi T,Asano G

更新日期：2001-05-01 00:00:00

abstract：:Immunodeficient mice are widely used for xenografts of human cells and tissue. The purpose of the present study was to investigate the characteristics of xenograft human tumor models using engraftment of various non-hematopoietic tumors in the NOD/SCID/gamma(c) (null) mouse. For tumor models, human solid tumor tissues...

journal_title：Pathology international

authors： Fujii E,Suzuki M,Matsubara K,Watanabe M,Chen YJ,Adachi K,Ohnishi Y,Tanigawa M,Tsuchiya M,Tamaoki N

更新日期：2008-09-01 00:00:00

abstract：:Intraductal tubulopapillary neoplasm (ITPN) has been recently reported in pancreas. We experienced an unusual intraductal growing bile duct tumor, which showed the same histopathologic and immunostaining profiles as ITPN of pancreas. A 72-year-old female patient visited hospital due to intrahepatic stone. The hilar bi...

journal_title：Pathology international

authors： Park HJ,Jang KT,Heo JS,Choi YL,Han J,Kim SH

更新日期：2010-09-01 00:00:00

abstract：:A 56-year-old male treated for a gastric yolk sac tumor with an adenocarcinomatous component is described. A mixed area of reticular and glandular neoplastic components was morphologically identified in this tumor. Immunohistochemically, the yolk sac tumor expressed alpha-fetoprotein (AFP), placental alkaline phosphat...

journal_title：Pathology international

authors： Suzuki T,Kimura N,Shizawa S,Yabuki N,Yamaki T,Sasano H,Nagura H

更新日期：1999-06-01 00:00:00

abstract：:A 53-year-old woman presented with Cushing's syndrome resulting from an adrenocortical adenoma, 6.5 cm in diameter and 75 g in weight, which is larger than usual. Endocrinological data of this patient showed adrenocorticotropin (ACTH)-independent hypercortisolemia. A computed tomography scan of the adrenal glands reve...

journal_title：Pathology international

authors： Karasawa R,Hotta M,Aiba M,Takano K

更新日期：2004-04-01 00:00:00

abstract：:A 7-year-old boy presented with midline swelling in the neck. On fine-needle aspiration cytology it was diagnosed as papillary carcinoma of the thyroid. The patient underwent total thyroidectomy. Histopathological examination, immunohistochemistry and electron microscopy revealed the presence of two intermingled compo...

journal_title：Pathology international

authors： Goyal R,Nada R,Rao KL,Radotra BD

更新日期：2006-02-01 00:00:00

abstract：:Reported herein is an unusual case of prostatic phyllodes tumor with exuberant glandular hyperplasia that led to misdiagnosis of adenocarcinoma. The tumor was detected in a 52-year-old man who had a 1 year history of dysuria. Adenocarcinoma of the prostate was diagnosed from a needle biopsy specimen. The patient recei...

journal_title：Pathology international

authors： Morikawa T,Nagata M,Tomita K,Kitamura T,Goto A,Chong JM,Fukayama M

更新日期：2006-03-01 00:00:00

abstract：:The role of chemokines, especially CXCL10/interferon-gamma-inducible protein 10 kDa (IP-10), a chemokine to attract CXCR3(+) T-helper 1-type CD4(+) T cells, is largely unknown in the pathophysiology of inflammatory bowel disease; ulcerative colitis and Crohn's disease. The authors have earlier shown that IP-10 neutral...

journal_title：Pathology international

authors： Suzuki K,Kawauchi Y,Palaniyandi SS,Veeraveedu PT,Fujii M,Yamagiwa S,Yoneyama H,Han GD,Kawachi H,Okada Y,Ajioka Y,Watanabe K,Hosono M,Asakura H,Aoyagi Y,Narumi S

更新日期：2007-07-01 00:00:00

abstract：:Many new members of the S-100 genes are known to be associated with cell differentiation, malignant transformation, and cell cycle. Of the S-100 genes examined in the present study, calcyclin, calpactin I light chain and calvasculin were expressed in most human epithelial tumor cells, and their expression levels diffe...

journal_title：Pathology international

authors： Matsumoto T,Murao S,Kito K,Kihana T,Matsuura S,Ueda N

更新日期：1997-06-01 00:00:00

abstract：:An association between autoimmune pancreatitis (AIP) and inflammatory abdominal aortic aneurysm (AAA) has never been reported. Reported herein is a case of IgG4-related inflammatory AAA accompanying metachronous AIP. A 77-year-old man presented with malaise and intermittent lower abdominal pain. Radiological examinati...

journal_title：Pathology international

authors： Ito H,Kaizaki Y,Noda Y,Fujii S,Yamamoto S

更新日期：2008-07-01 00:00:00

abstract：:The CDKN2 gene encodes two structurally different proteins: a cyclin-dependent kinase inhibitor, p16, which regulates retinoblastoma protein (pRb)-dependent G1 arrest, and a cell cycle inhibitor, p14ARF, which blocks MDM2-induced p53 degradation resulting in an increase in p53 levels that leads to cell cycle arrest. R...

journal_title：Pathology international

authors： Sano T,Masuda N,Oyama T,Nakajima T

更新日期：2002-05-01 00:00:00

abstract：:Our objective is to elucidate the usefulness of maspin/p53 double immunostaining on biliary brushing cytology specimens. We first examined the expression of maspin in the biliary epithelium with variable degrees of dysplasia using surgically resected specimens (n = 56). Maspin appeared to be overexpressed in a stepwis...

journal_title：Pathology international

authors： Kanzawa M,Sanuki T,Onodera M,Fujikura K,Itoh T,Zen Y

更新日期：2017-02-01 00:00:00

abstract：:A case of lymphoid hyperplasia arising in the large intestine of a 54-year-old woman is described. Barium enema X-ray and colonoscopic examination revealed multiple small polyps in the right side of the colon. Pathological findings from forceps biopsy revealed similar features to a mucosa-associated lymphoid tissue (M...

journal_title：Pathology international

authors： Nagaoka S,Bandoh T,Takemura T

更新日期：2000-09-01 00:00:00

abstract：:The value of fluorescence in situ hybridization (FISH) as an aid to deciding the prognosis for lung carcinoma patients, comparing quantitatively the signal from the p53 gene (17p13.1) on chromosome 17, was studied. A dual-labeling technique was used, using probes for the centromeric region of chromosome 17 and for the...

journal_title：Pathology international

authors： Kawai T,Hiroi S,Nakanishi K,Sakurai Y,Torikata C

更新日期：2004-06-01 00:00:00

abstract：:This study aims to evaluate the impact on the implementation of multiple strategies to improve medical student's pathology learning experience. In two consecutive years, medical students after a whole year of enrolling in pathology teaching, were invited to complete questionnaires rating and commenting on the personal...

journal_title：Pathology international

authors： Gopalan V,Kasem K,Pillai S,Olveda D,Ariana A,Leung M,Lam AKY

更新日期：2018-07-24 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy is an unusual malignancy-related respiratory complication characterized by multiple microthrombi and intimal myofibroblast proliferation. Its clinical manifestation is subacute respiratory failure with pulmonary hypertension. Herein is reported a case of pulmonary tumor throm...

journal_title：Pathology international

authors： Sakashita N,Yokose C,Fujii K,Matsumoto M,Ohnishi K,Takeya M

更新日期：2007-06-01 00:00:00