Diffuse pulmonary ossification in permanent vegetative state.

abstract：:The KIT, epidermal growth factor receptor (EGFR) and HER-2 oncoproteins have tyrosine kinase activity and are molecular targets in human cancer therapy. To clarify the significance of KIT, EGFR, and HER-2 in undifferentiated thyroid carcinoma (UTC), the expression of these receptors and tyrosine phosphorylation was ex...

journal_title：Pathology international

authors： Murakawa T,Tsuda H,Tanimoto T,Tanabe T,Kitahara S,Matsubara O

更新日期：2005-12-01 00:00:00

abstract：:Myofibroblasts have ultrastructural and functional characteristics intermediate between fibroblasts and smooth muscle cells. Previous studies indicated that most myofibroblasts express actin and vimentin but not desmin immunophenotypes. Two benign intramuscular myofibroblastic tumors which displayed a desmin-positive ...

journal_title：Pathology international

authors： Yang P,Hirose T,Seki K,Hasegawa T,Hizawa K,Sano T

更新日期：1996-09-01 00:00:00

abstract：:MRL/MpTn-gld/gld (MRL/gld) mice, which are deficient in a functional Fas ligand (FasL), spontaneously develop autoimmune diseases involving both lethal glomerulonephritis and systemic arteritis, while MRL/Mp-+/+ (MRL/+) and C3H/HeJ-gld/gld (C3H/gld) do not. To determine the cells responsible for the development of glo...

journal_title：Pathology international

authors： Ito MR,Ono M,Itoh J,Nose M

更新日期：2003-08-01 00:00:00

abstract：:A 51-year-old woman with a history of eating raw fish over a period of 2 weeks developed a progressive abdominal pain and leukocytosis with signs of small bowel obstruction. Eosinophilia was not detected in the peripheral blood. The patient underwent surgery to clarify the possibility of ileus. Partial small bowel nea...

journal_title：Pathology international

authors： Masui N,Fujima N,Hasegawa T,Kigawa S,Kagei N,Nagashima K,Shimizu Y

更新日期：2006-06-01 00:00:00

abstract：:Pituicytoma is a rare low-grade glial neoplasm that originates in the neurohypophysis or infundibulum. Because of its rare occurrence, the morphology and differentiation of pituicytoma have not been fully clarified. Here, we report a case of pituicytoma with unusual histological features mimicking ependymoma, but exhi...

journal_title：Pathology international

authors： Kwon MJ,Suh YL

更新日期：2011-10-01 00:00:00

abstract：:Multiple carcinomas of the pancreatico-biliary tree are rare. A 53 year old Japanese man was diagnosed as having an adenocarcinoma in the papilla of Vater. During the operation, he was also found to have a polypoid mass in the common bile duct. While cutting the operative specimen into stepwise sections, a small tumor...

journal_title：Pathology international

authors： Nishihara K,Tsuneyoshi M,Shimura H,Yasunami Y

更新日期：1994-04-01 00:00:00

abstract：:A case of gliosarcoma composed of glioblastoma and liposarcoma is presented. A 70-year-old Japanese man was admitted to hospital because of dysarthria and aphasia. Magnetic resonance imaging indicated a brain tumor located in the temporal-parietal area of the left hemisphere. He rejected any therapy and died of respir...

journal_title：Pathology international

authors： Fukuda T,Yasumichi K,Suzuki T

更新日期：2008-06-01 00:00:00

abstract：:In 2004, two groups reported somatic mutations in the gene for the epidermal growth factor receptor (EGFR) in patients with non-small cell lung cancer (NSCLC), which were highly correlated with the clinical response to the anticancer drug, gefitinib. Since then, a tremendous amount of knowledge has accumulated, and sh...

journal_title：Pathology international

authors： Yatabe Y,Mitsudomi T

更新日期：2007-05-01 00:00:00

abstract：:An extremely rare case of unilateral gonadoblastoma with mixed germ cell tumor arising in the ovary of a 27-year-old woman with 46,XX karyotype and two successful pregnancies is reported. The mixed germ cell tumor was composed of choriocarcinoma, embryonal carcinoma, yolk sac tumor, immature teratoma and dysgerminoma....

journal_title：Pathology international

authors： Zhao S,Kato N,Endoh Y,Jin Z,Ajioka Y,Motoyama T

更新日期：2000-04-01 00:00:00

abstract：:Resistance to retroviral infection is often regulated by multiple genes that control different aspects of the host-virus interaction. Genetically distinct inbred strains of mice differ in their susceptibility to retrovirus and have allowed the identification of several host-resistant loci that regulate the host defens...

journal_title：Pathology international

authors： Kitagawa M,Aizawa S,Ikeda H,Hirokawa K

更新日期：1996-10-01 00:00:00

abstract：:The clinicopathological significance of colonic and small-intestinal phenotypes has hitherto remained unclear in gastric cancers. The purpose of the present study was therefore to examine 86 gastric carcinomas histologically and phenotypically using several phenotypic markers, including colon-specific carbonic anhydra...

journal_title：Pathology international

authors： Mizoshita T,Tsukamoto T,Tanaka H,Takenaka Y,Kato S,Cao X,Joh T,Tatematsu M

更新日期：2005-10-01 00:00:00

abstract：:Transforming acidic coiled-coil containing protein 3 (TACC3) is known to be involved in the control of normal cell growth and differentiation and in mechanisms of unregulated growth leading to tumorigenesis. The aim of the present paper was to determine the rate of TACC3 expression in a non-small cell lung cancer (NSC...

journal_title：Pathology international

authors： Jung CK,Jung JH,Park GS,Lee A,Kang CS,Lee KY

更新日期：2006-09-01 00:00:00

abstract：:Secondary (metastatic) neoplasms to the ovary often cause diagnostic problems, especially those tumors that produce large, symptomatic ovarian tumors that masquerade clinically and pathologically as primary ovarian tumors of surface epithelial type. Most of these tumors arise from organs of the digestive system. Excep...

journal_title：Pathology international

authors： Hart WR

更新日期：2005-05-01 00:00:00

abstract：:Stenosing flexor tenosynovitis, trigger finger, is a common clinical disorder causing painful locking or contracture of the involved digits, and most instances are idiopathic. This problem is generally caused by a size mismatch between the swollen flexor tendon and the thickened first annular pulley. Although hypertro...

journal_title：Pathology international

authors： Uchihashi K,Tsuruta T,Mine H,Aoki S,Nishijima-Matsunobu A,Yamamoto M,Kuraoka A,Toda S

更新日期：2014-06-01 00:00:00

abstract：:Phyllodes tumor is a very rare neoplasm which accounts for 2.5% of all fibroepithelial lesions of the breast. The mesenchymal component of a malignant phyllodes tumor frequently contains heterologous components. We report a case of malignant phyllodes tumor. The patient was a 40-year-old woman with a lump on the left ...

journal_title：Pathology international

authors： Kuroda N,Sugimoto T,Ueda S,Takahashi T,Moriki T,Sonobe H,Miyazaki E,Hayashi Y,Toi M,Hiroi M,Enzan H

更新日期：2001-04-01 00:00:00

abstract：:Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare, recently recognized neoplasm occurring predominantly in the subcutaneous tissue of the lower limbs of adults. We report a case of PHAT in an 83-year-old woman who presented with a 5.0 x 5.0 x 2.0 cm mass in the soft part of her left thigh. Histologically, the...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T

更新日期：2002-10-01 00:00:00

abstract：:The aims of this study were to identity the roles of tumor vessels and hormone receptor status in normal, hyperplastic, and neoplastic endometrium, and to explore their relationships with other prognostic factors of endometrial adenocarcinoma. Endometrial curettage specimens of proliferative phase and secretory phase ...

journal_title：Pathology international

authors： Nunobiki O,Taniguchi E,Ishii A,Tang W,Utsunomiya H,Nakamura Y,Mori I,Kakudo K

更新日期：2003-12-01 00:00:00

abstract：:This study aims to evaluate the impact on the implementation of multiple strategies to improve medical student's pathology learning experience. In two consecutive years, medical students after a whole year of enrolling in pathology teaching, were invited to complete questionnaires rating and commenting on the personal...

journal_title：Pathology international

authors： Gopalan V,Kasem K,Pillai S,Olveda D,Ariana A,Leung M,Lam AKY

更新日期：2018-07-24 00:00:00

abstract：:The diagnosis of the rare neoplasm histiocytic sarcoma (HS) relies on morphology and the presence of immunophenotypic features of histiocytic lineage. More than 57 cases, including 16 cases involving the gastrointestinal (GI) tract, have been described since the World Health Organization issued its classification syst...

journal_title：Pathology international

authors： Miyazaki T,Arihiro S,Mitobe J,Aoki Y,Takikawa S,Saruta M,Matsuoka M,Koike K,Kato T,Kashiwagi H,Ikegami M,Tajiri H

更新日期：2013-02-01 00:00:00

abstract：:Osteosarcoma is one of the neoplasms that may occur following exposure to radiation. A case of osteosarcoma arising in the craniofacial bone with a short latency period of 3 years after radiotherapy for maxillary squamous cell carcinoma is described. A 64-year-old-man underwent right partial maxillectomy and chemoradi...

journal_title：Pathology international

authors： Matsuyama A,Yonemitsu N,Hayashida S,Watanabe K,Sugihara H,Inokuchi A

更新日期：2003-01-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) with TP63 rearrangement is a new entity and has the most dismal prognosis in all types of ALCL. This might be due to the resulting fusion protein having N-terminal truncated p63 with high oncogenic ability. Since this N-terminal domain has the function of tumor suppressor activity...

journal_title：Pathology international

authors： Yamashita T,Higashi M,Kawano R,Momose S,Tokuhira M,Kizaki M,Tamaru JI

更新日期：2019-03-01 00:00:00

abstract：:Desminopathy is a familial or sporadic skeletal and cardiac muscular dystrophy caused by mutation in the desmin gene. Desmin-reactive deposits in the affected muscles are the morphological hallmarks of this disease. Herein is reported an autopsy case of a 57-year-old Japanese man with adult-onset skeletal muscle weakn...

journal_title：Pathology international

authors： Yuri T,Miki K,Tsukamoto R,Shinde A,Kusaka H,Tsubura A

更新日期：2007-01-01 00:00:00

abstract：:Metallothionein (MT) has been reported to play important physiological roles in the human body, but the distribution and significance of MT is not fully understood. In order to analyze MT expression, three kinds of polyclonal MT fragment antibodies were developed against NH2-terminal, middle regional and COOH-terminal...

journal_title：Pathology international

authors： Nakazato K,Nakajima K,Kusakabe T,Suzuki K,Nagamine T

更新日期：2008-12-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare clinicopathological entity causing severe pulmonary hypertension. Its histological features include widespread tumor emboli along with fibrocellular intimal proliferation and thrombus formation in the small arteries and arterioles of the lungs. The result is ...

journal_title：Pathology international

authors： Chinen K,Kazumoto T,Ohkura Y,Matsubara O,Tsuchiya E

更新日期：2005-01-01 00:00:00

abstract：:We report a case of glomerular cystic kidney disease (GCKD) associated with tuberous sclerosis complex (TSC) in a neonate. The patient displayed progressive abdominal enlargement attributed to GCKD associated with TSC. After birth, the right kidney was resected because it compressed his liver and right lung, and possi...

journal_title：Pathology international

authors： Murakami A,Gomi K,Tanaka M,Ohyama M,Itani Y,Ishikawa H,Aida N,Furuya M,Tanaka Y

更新日期：2012-03-01 00:00:00

abstract：:Reported herein are seven cases of a histologically distinct oncocytic papillary renal cell carcinoma (OPRCC) with an inverted nuclear pattern. To define its prognostic significance, the clinicopathological features of OPRCC were compared to those of types 1 and 2 PRCC. The median age of the seven patients was 67 year...

journal_title：Pathology international

authors： Park BH,Ro JY,Park WS,Jee KJ,Kim K,Gong G,Cho YM

更新日期：2009-03-01 00:00:00

abstract：:The first tumor, node, metastasis (TNM) classification for stomach tumors was published in the second edition of the TNM classification of malignant tumors in 1974 and was followed by additional editions up to the seventh edition published in 2010. In the Buffalo Meeting 2008 a harmonization between the Eastern (Japan...

journal_title：Pathology international

authors： Wittekind C

更新日期：2015-08-01 00:00:00

abstract：:We report a case of small intestinal type adenocarcinoma arising in retroperitoneal mature cystic teratoma in a young male. The patient initially experienced intermittent abdominal pain, and radiographic workup revealed an encapsulated retroperitoneal mass. A laparotomy was performed and the resected specimen represen...

journal_title：Pathology international

authors： Terado Y,Kurata A,Ishida T,Imamura T,Sakamoto A

更新日期：2010-10-01 00:00:00

abstract：:Reported herein is an unusual case of prostatic phyllodes tumor with exuberant glandular hyperplasia that led to misdiagnosis of adenocarcinoma. The tumor was detected in a 52-year-old man who had a 1 year history of dysuria. Adenocarcinoma of the prostate was diagnosed from a needle biopsy specimen. The patient recei...

journal_title：Pathology international

authors： Morikawa T,Nagata M,Tomita K,Kitamura T,Goto A,Chong JM,Fukayama M

更新日期：2006-03-01 00:00:00

abstract：:A case of primary esophageal adenocarcinoma in a 64-year-old man is reported. An ulcerating tumor was located in the middle intrathoracic esophagus. Histopathological examination revealed a moderately differentiated adenocarcinoma, which had invaded down to the adventitia. The cancerous tubuli were lined by flattened ...

journal_title：Pathology international

authors： Endoh Y,Miyawaki M,Tamura G,Watanabe H,Motoyama T

更新日期：1999-02-01 00:00:00