Unilateral glomerulocystic kidney disease associated with tuberous sclerosis complex in a neonate.

abstract：:Histological grading of prostate cancer is one of the most important tissue-based parameters for prediction of outcome and treatment response. Gleason grading remains the foundation of prostate cancer grading, but has undergone a series of changes in the past 30 years, often initiated by consensus conference decisions...

journal_title：Pathology international

authors： Egevad L,Delahunt B,Yaxley J,Samaratunga H

更新日期：2019-02-01 00:00:00

abstract：:A case of primary leiomyosarcoma of a thoracic vertebra associated with a compression fracture in a 75-year-old woman was preoperatively thought to be granulation tissue. Surgical decompression was performed and the histological and immunohistochemical studies established the diagnosis of leiomyosarcoma. Based on the ...

journal_title：Pathology international

authors： Sasaguri T,Tanimoto A,Kimura S,Kohno Y,Hirasawa M,Matsuki Y,Abe K,Hashimoto H,Hamada T,Sasaguri Y

更新日期：2004-01-01 00:00:00

abstract：:Gastric lipomas are uncommon lesions, usually single and located in the antrum. Common symptoms include upper digestive bleeding, anemia, and intestinal obstruction. Alternatively, they may remain asymptomatic, and detectable only at autopsy. A case of a 72-year-old man, who died of myocardial infarction, was found at...

journal_title：Pathology international

authors： Ventura L,Leocata P,Guadagni S,Ventura T

更新日期：1997-08-01 00:00:00

abstract：:To examine the relationship between the scavenger receptor A (SRA) index (the number of SRA+ cells observed in 10 high power fields of peripheral blood (PB) smear samples; normal upper limit <30) and coronary thrombus, 389 thrombi obtained from 393 patients with acute ST elevation myocardial infarction were examined. ...

journal_title：Pathology international

authors： Emura I,Usuda H,Fujita T,Ebe K,Nagai T

更新日期：2011-06-01 00:00:00

abstract：:In order to confirm the role of 14-3-3 sigma (sigma) as a tumor suppressor in breast carcinogenesis, we have studied the expression of 14-3-3sigma immunohistochemically in usual ductal hyperplasia (UDH), ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) breast lesions. Immunostaining for estrogen rec...

journal_title：Pathology international

authors： Simooka H,Oyama T,Sano T,Horiguchi J,Nakajima T

更新日期：2004-08-01 00:00:00

abstract：:Tight junctions are intercellular junctions adjacent to the apical ends of paracellular spaces. They have two classical functions, the barrier function and the fence function. The former regulates the passage of ions, water and various molecules through paracellular spaces, and is thus related to edema, jaundice, diar...

journal_title：Pathology international

authors： Sawada N

更新日期：2013-01-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) is a heterodimeric polypeptide growth factor that has pleiotropic roles, including those of mitogen, motogen and morphogen. The HGF receptor is characterized as a c-Met proto-oncogene product (c-Met), which is a heterodimeric tyrosine kinase receptor. Hepatocyte growth factor acts as a m...

journal_title：Pathology international

authors： Motoi T,Ishida T,Kuroda M,Horiuchi H,Oka T,Matsumoto K,Nakamura T,Machinami R

更新日期：1998-10-01 00:00:00

abstract：:Reported herein is a case of benign clear cell tumor of the lung in a 60-year-old man. Chest X-ray and CT examination revealed an abnormal nodule with homogenous density and a clear margin in the lower lobe of the left lung. The resected tumor was 13 mm in size, well-circumscribed and was graysh-white on cut surface. ...

journal_title：Pathology international

authors： Adachi Y,Kitamura Y,Nakamura H,Taniguchi Y,Miwa K,Horie Y,Hayashi K

更新日期：2006-08-01 00:00:00

abstract：:A case of primary small cell (oat cell) carcinoma of the breast in a 41-year-old woman is presented. The patient was alive and well without disease 16 months after modified radical mastectomy and subsequent chemotherapy. The tumor cells revealed morphologic similarity to oat cell carcinoma of the lung and immunohistoc...

journal_title：Pathology international

authors： Yamasaki T,Shimazaki H,Aida S,Tamai S,Tamaki K,Hiraide H,Mochizuki H,Matsubara O

更新日期：2000-11-01 00:00:00

abstract：:Presented is the first Japanese case of ossifying renal tumor of infancy (ORTI), which is an extremely rare tumor and of which only nine cases have been reported in the literature. The patient was a four-month-old Japanese boy presenting as hematuria. A small nodular tumor (approximately 1 cm in size) protruded into t...

journal_title：Pathology international

authors： Ito J,Shinohara N,Koyanagi T,Hanioka K

更新日期：1998-02-01 00:00:00

abstract：:YU-311 is a monoclonal antibody that reacts with a human leukemia cell line resistant for cytosine arabinoside and that identifies a 92 kDa membrane protein. The reactivity of YU-311 in normal organs, various non-hematopoietic tumors and in mast cell tumors in formalin-fixed, paraffin-embedded specimens was examined u...

journal_title：Pathology international

authors： Fukuda T,Kamishima T,Kakihara T,Yamada T,Matsumoto K,Uchiyama M,Suzuki T

更新日期：1997-08-01 00:00:00

abstract：:A case of serous cystadenocarcinoma of the pancreas in an 85-year-old woman is reported. The tumor extensively involved the body and tail of the pancreas and contiguously invaded the spleen. The histopathology of the tumor was similar to that of serous cystadenoma, but mild nuclear hyperchromatism and atypism were not...

journal_title：Pathology international

authors： Shintaku M,Arimoto A,Sakita N

更新日期：2005-07-01 00:00:00

abstract：:A 79-year-old man presented with back pain. Chest CT scan showed elevated nodular lesions in the right parietal pleurae with pleural effusion. There were no intrapulmonary or mediastinal abnormalities. Under local anesthesia, right thoracoscopy and subsequent thoracoscopic pleural resection were performed using an ins...

journal_title：Pathology international

authors： Kawahara K,Sasada S,Nagano T,Suzuki H,Kobayashi M,Matsui K,Takata K,Yoshino T,Michida T,Iwasaki T

更新日期：2008-04-01 00:00:00

abstract：:We describe a rare case of dedifferentiated liposarcoma with features resembling chondroblastic osteosarcoma in the dedifferentiated component. The tumor was removed from the left thigh in a 78-year-old male. It consisted of a well-differentiated liposarcoma and an anaplastic component that contained numerous osteoid ...

journal_title：Pathology international

authors： Yamamoto T,Matsushita T,Marui T,Mizuno K,Minami R,Hayashi Y,Hanioka K

更新日期：2000-07-01 00:00:00

abstract：:The biopsy-based diagnosis of autoimmune pancreatitis (AIP) is difficult but is becoming imperative for pathologists due to the increased amount of endoscopic ultrasound-guided biopsy tissue. To cope with this challenge, we propose guidance for the biopsy diagnosis of type 1 AIP. This guidance is for pathologists and ...

journal_title：Pathology international

authors： Notohara K,Kamisawa T,Fukushima N,Furukawa T,Tajiri T,Yamaguchi H,Aishima S,Fukumura Y,Hirabayashi K,Iwasaki E,Kanno A,Kasashima S,Kawashima A,Kojima M,Kubota K,Kuraishi Y,Mitsuhashi T,Naito Y,Naitoh I,Nakase H,Ni

更新日期：2020-10-01 00:00:00

abstract：:Microwave cell death (MCD) is unique in that microscopic morphology and antigenicity are well preserved, while enzymatic activity is lost. The aim of the present study was to carry out DNA electrophoresis, polymerase chain reaction (PCR) amplification and terminal deoxynucleotidyl transferase-mediated dUTP nick end-la...

journal_title：Pathology international

authors： Mori I,Ozaki T,Tabuse K,Utsunomiya H,Taniguchi E,Kakudo K

更新日期：2009-05-01 00:00:00

abstract：:This study aims to evaluate the impact on the implementation of multiple strategies to improve medical student's pathology learning experience. In two consecutive years, medical students after a whole year of enrolling in pathology teaching, were invited to complete questionnaires rating and commenting on the personal...

journal_title：Pathology international

authors： Gopalan V,Kasem K,Pillai S,Olveda D,Ariana A,Leung M,Lam AKY

更新日期：2018-07-24 00:00:00

abstract：:A 58-year-old man with a 1 year history of progressive abdominal distension underwent a laparotomy for pseudomyxoma peritonei. The mucin was identified and characterized in the present study. Approximately 6 L of crude mucus in the sol (highly viscous) and gel (semisolid) phases was obtained from the patient's periton...

journal_title：Pathology international

authors： Mall AS,Chirwa N,Govender D,Lotz Z,Tyler M,Rodrigues J,Kahn D,Goldberg P

更新日期：2007-08-01 00:00:00

abstract：:A 15 month old female, who had suffered from ventricular tachycardia from the prenatal period, experienced cardiac arrest at home. Once she had recovered, ventricular tachycardia occurred repeatedly. She died 7 months after admission. At autopsy, the heart showed many yellowish white nodules in the endocardium. Histol...

journal_title：Pathology international

authors： Otani M,Hoshida H,Saji T,Matsuo N,Kawamura S

更新日期：1995-10-01 00:00:00

abstract：:Amyloidosis refers to a group of diseases with amyloid fibrils deposited in various organs and is classified into more than 30 diseases in humans based on the kind of amyloid protein. In order to elucidate the molecular pathogenesis of human amyloidosis, we studied the molecular mechanism of amyloid fibril formation i...

journal_title：Pathology international

authors： Naiki H,Okoshi T,Ozawa D,Yamaguchi I,Hasegawa K

更新日期：2016-04-01 00:00:00

abstract：:Tumor suppressor in lung cancer-1 (TSLC1) is an intercellular adhesion molecule of the immunoglobulin superfamily. There is little information regarding the developmental expression profiles. In an attempt to clarify the distribution of TSLC1 proteins in mouse embryos tissue by immunohistochemistry, it was found that ...

journal_title：Pathology international

authors： Usami Y,Ito A,Ohnuma K,Fuku T,Komori T,Yokozaki H

更新日期：2007-02-01 00:00:00

abstract：:We studied the extensive molecular alterations of endometrial endometrioid adenocarcinoma (EEA) using a crypt isolation method. We analyzed copy number variation (CNV) using a single nucleotide polymorphism (SNP) array, genetic mutations (KRAS, BRAF, p53, PIK3CA), DNA methylation and microsatellite instability (MSI) s...

journal_title：Pathology international

authors： Suga Y,Sugai T,Uesugi N,Kawasaki T,Fukagawa T,Yamamoto E,Ishida K,Suzuki H,Sugiyama T

更新日期：2015-05-01 00:00:00

abstract：:An 18-year-old man who suffered from panniculitis involving the entire left lower limb after exertional rhabdomyolysis is reported. A high fever (>39 degrees C) and leukocytosis (>20,000/microL) persisted for 1 week, and his general status deteriorated rapidly into pre-disseminated intravascular coagulation, complicat...

journal_title：Pathology international

authors： Kanai Y,Iwaya K,Kuroda M,Harada M,Hirata F,Mukai K

更新日期：2000-10-01 00:00:00

abstract：:Interactions among p53, bcl-2 and Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in nasopharyngeal carcinoma (NPC) cells were evaluated by gene cotransfections. The data showed that bcl-2 expression was not only able to prevent the growth suppression induced by wild-type p53 but was also paradoxically able ...

journal_title：Pathology international

authors： Sheu LF,Chen A,Lee HS,Hsu HY,Yu DS

更新日期：2004-07-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVGC) is defined as a neoplasm comprising monoclonal proliferation of EBV-infected gastric epithelial cells. Although the typical histology is gastric carcinoma with lymphoid stroma (GCLS), the histologic features of the tumor vary. We report herein the case of a...

journal_title：Pathology international

authors： Shimizu A,Takahashi T,Kushima R,Sentani K,Yasui W,Matsuno Y

更新日期：2018-01-01 00:00:00

abstract：:The clinicopathological significance of colonic and small-intestinal phenotypes has hitherto remained unclear in gastric cancers. The purpose of the present study was therefore to examine 86 gastric carcinomas histologically and phenotypically using several phenotypic markers, including colon-specific carbonic anhydra...

journal_title：Pathology international

authors： Mizoshita T,Tsukamoto T,Tanaka H,Takenaka Y,Kato S,Cao X,Joh T,Tatematsu M

更新日期：2005-10-01 00:00:00

abstract：:High-grade transformation (HGT)/dedifferentiation is an unusual phenomenon in salivary gland carcinomas. Here we report a case of adenoid cystic carcinoma (ACC) with HGT/dedifferentiation to myoepithelial carcinoma, occurring in the epipharynx of a 42-year-old woman. The surgically resected tumor was a pedunculated ma...

journal_title：Pathology international

authors： Tando S,Nagao T,Kayano K,Fushiki S,Itoh K

更新日期：2018-02-01 00:00:00

abstract：:We report a case of a 57-year-old man who developed a fibrosclerosing lesion in the submandibular gland and idiopathic retroperitoneal fibrosis (IRF) involving the unilateral periureteral region within a year. Both lesions were resected surgically because of the suspicion of neoplasm. Pathologic examination revealed s...

journal_title：Pathology international

authors： Sekine S,Nagata M,Watanabe T

更新日期：1999-07-01 00:00:00

abstract：:An 80-year-old woman with a pleomorphic carcinoma (PC) producing hCG was admitted to Nippon Steel Hirohata Hospital because of an abnormal shadow on CT seen during a follow-up examination after surgery for breast cancer. A right upper lobectomy was performed due to rapid growth of the shadow 3 months later. Macroscopi...

journal_title：Pathology international

authors： Hirano H,Yoshida T,Sakamoto T,Yoshimura H,Fukuoka M,Tachibana S,Saito H,Ohkubo E,Nakasho K,Nishigami T

更新日期：2007-10-01 00:00:00

abstract：:The protective effect of Brazilian propolis and its extract Artepillin C against ferric nitrilotriacetate (Fe-NTA)-induced renal lipid peroxidation and carcinogenesis was studied in male ddY mice. Fe-NTA-induced renal lipid peroxidation leads to a high incidence of renal cell carcinoma (RCC) in mice. Administration of...

journal_title：Pathology international

authors： Kimoto T,Koya S,Hino K,Yamamoto Y,Nomura Y,Micallef MJ,Hanaya T,Arai S,Ikeda M,Kurimoto M

更新日期：2000-09-01 00:00:00