Primary pulmonary choriocarcinoma combined with adenocarcinoma.

abstract：:Patients with pulmonary small cell carcinoma are well known to have a poor prognosis. However, predictors of prognosis and treatment outcome have not been reported for this type of cancer. We examined whether excision repair cross-complementation group 1 (ERCC1), phosphorylated Akt (p-Akt), phosphorylated mammalian ta...

journal_title：Pathology international

authors： Ikeda S,Takabe K,Inagaki M,Suzuki K

更新日期：2010-11-01 00:00:00

abstract：:Nodular fasciitis (NF) is a self-limiting benign disease that is characterized by rapid proliferation of fibroblastic and myofibroblastic cells. The characteristic gene fusion containing the USP6 gene is a genetic hallmark of NF and MYH9-USP6 is the most frequent fusion, suggesting that NF is not a reactive condition ...

journal_title：Pathology international

authors： Teramura Y,Yamazaki Y,Tanaka M,Sugiura Y,Takazawa Y,Takeuchi K,Nakayama T,Kaneko T,Musha Y,Funauchi Y,Ae K,Matsumoto S,Nakamura T

更新日期：2019-12-01 00:00:00

abstract：:A 28-year-old woman complained of irregular menstruation. Abdominal ultrasound and magnetic resonance imaging (MRI) examinations revealed a cystic tumor in the left ovary. A histological examination of the resected ovary revealed that the lesion was a mature cystic teratoma. In this tumor, components such as skin with...

journal_title：Pathology international

authors： Kuroda N,Hirano K,Inui Y,Yamasaki Y,Toi M,Nakayama H,Hiroi M,Enzan H

更新日期：2001-11-01 00:00:00

abstract：:We present a case of uterine intravenous leiomyomatosis associated with multiple pulmonary metastases with bullae-like cystic change. A 53-year-old woman who had undergone hysterectomy 5 years previously underwent an operation for multiple pulmonary nodules with bullae formation. After resection of several large bulla...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T,Hisayoshi T,Asano G

更新日期：2001-05-01 00:00:00

abstract：:Malignant lymphoma arising in the stomach of a 23-year-old Japanese man with systemic sarcoidosis is presented. The patient was followed because of systemic sarcoidosis involving the lungs, eyes, and lymph nodes. Biopsy specimens from the stomach were repeated because of recurrent epigastralgia and multiple ulceration...

journal_title：Pathology international

authors： Fukuda T,Sato K,Tachikawa S,Ohnuki K,Ohtani H,Suzuki T

更新日期：1997-12-01 00:00:00

abstract：:An extremely rare case of malignant mesothelioma of the pericardium is reported. The tumor appeared to be the biphasic type of diffuse malignant mesothelioma which present many small to fine lipid droplets in the cytoplasm, particularly that of the epithelial cell, and a positive immunohistochemical reaction with anti...

journal_title：Pathology international

authors： Ohmori T,Arita N,Okada K,Kondo M,Tabei R

更新日期：1995-08-01 00:00:00

abstract：:The CDKN2 gene encodes two structurally different proteins: a cyclin-dependent kinase inhibitor, p16, which regulates retinoblastoma protein (pRb)-dependent G1 arrest, and a cell cycle inhibitor, p14ARF, which blocks MDM2-induced p53 degradation resulting in an increase in p53 levels that leads to cell cycle arrest. R...

journal_title：Pathology international

authors： Sano T,Masuda N,Oyama T,Nakajima T

更新日期：2002-05-01 00:00:00

abstract：:A subcutaneous myopericytoma-type perivascular myoma arising in the elbow of a 61-year-old woman is described. The tumor was well demarcated and consisted microscopically of small ovoid and spindle cells arranged in a concentric fashion, surrounding small to medium-sized vessels and imparting a superficial resemblance...

journal_title：Pathology international

authors： Mikami Y,Shiomi T,Manabe T

更新日期：2002-01-01 00:00:00

abstract：:A 54-year-old Japanese woman was referred with a gallbladder tumor. Based on the results of the computed tomography scan, endoscopic retrograde cholangiopancreatography, and magnetic resonance cholangiopancreatography, a mucin-producing neoplasm of the gallbladder associated with pancreaticobiliary maljunction was dia...

journal_title：Pathology international

authors： Meguro Y,Fukushima N,Koizumi M,Kasahara N,Hydo M,Morishima K,Sata N,Lefor AT,Yasuda Y

更新日期：2014-09-01 00:00:00

abstract：:In order to clarify the relationship between cyclin D1 and D2 (CD1/CD2) overexpression and progression, 191 gastric cancer cases (81 early and 110 advanced cancers) were investigated using the 5D4 monoclonal antibody for both CD1/CD2 in immunohistochemistry. 5D4 immunoreactivity was noted in 68 (35.6%) cases, staining...

journal_title：Pathology international

authors： Yasogawa Y,Takano Y,Okayasu I,Kakita A

更新日期：1998-09-01 00:00:00

abstract：:Rhinoscleroma is an uncommon chronic, destructive infection of the respiratory mucosa caused by Klebsiella rhinoscleromatis. This coccobacillus can be found in the typical histiocytes, the Mikulicz cells. Extranasal and nodal involvement in this disease is rare, but documented. Rosai-Dorfman disease or sinus histiocyt...

journal_title：Pathology international

authors： Kasper HU,Hegenbarth V,Buhtz P

更新日期：2004-02-01 00:00:00

abstract：:We report a case of cutaneous squamous cell carcinoma (CSCC), initially coexisting with invasive extramammary Paget's disease (EMPD), in the scrotum of an 84-year-old man. The patient initially had a rash and pruritus before presenting with a pedunculated scrotal mass surrounded by widespread erythema. He underwent to...

journal_title：Pathology international

authors： Kitano A,Izumi M,Tamura K,Tonegawa M,Etou T,Kishida Y

更新日期：2019-10-01 00:00:00

abstract：:The histology of basaloid squamous cell carcinoma (BSCC) can resemble that of adenoid cystic carcinoma (AdCC). Herein, we report two cases of BSCC with adenoid cystic-like features (BSCC-AdC). We collected cases of AdCC and BSCC of the head and neck region, extracted two cases with unusual histology, and reexamined th...

journal_title：Pathology international

authors： Kusafuka K,Yagi H,Baba S,Inagaki H,Tsuchiya C,Hirata K,Muramatsu A,Suzuki M,Arai K,Terada T

更新日期：2020-10-01 00:00:00

abstract：:A case of small cell carcinoma of the gall-bladder is described. Immunohistochemically, the tumor cells were positive for chromogranin A, synaptophysin and neuronspecific enolase, which suggests that they derived from neuroendocrine cells. The overlying and surrounding epithelium of the tumor showed intestinal metapla...

journal_title：Pathology international

authors： Kuwabara H,Uda H

更新日期：1998-04-01 00:00:00

abstract：:Differentiation of malignant pleural mesothelioma (MPM) from benign mesothelial proliferation remains problematic. Loss of nuclear staining of BRCA1-associated protein 1 (BAP1; detected using immunohistochemistry (IHC)) and homozygous deletion (HD) of p16 (detected using fluorescence in situ hybridization (FISH)) are ...

journal_title：Pathology international

authors： Hida T,Hamasaki M,Matsumoto S,Sato A,Tsujimura T,Kawahara K,Iwasaki A,Okamoto T,Oda Y,Honda H,Nabeshima K

更新日期：2016-10-01 00:00:00

abstract：:Alterations in cell surface carbohydrates on human lymphoma cell lines with different spontaneous metastatic potential in the severe combined immunodeficiency (SCID) mouse model were analyzed. A difference in cell surface carbohydrates between high- (HBL-2, HBL-7 and HBL-8) and no- or low-(HBL-4, HBL-6, Daudi and Raji...

journal_title：Pathology international

authors： Abe M,Suzuki O,Tasaki K,Tominaga K,Wakasa H

更新日期：1996-12-01 00:00:00

abstract：:We compared the c-erbB-2 protein overexpression status detected by the HercepTestTM (DAKO A/S, Grostrup, Denmark) with another conventional immunohistochemistry system using an anti-c-erbB-2 rabbit polyclonal antibody (Nichirei Co., Tokyo, Japan) and with the c-erbB-2 gene amplification status detected by Southern blo...

journal_title：Pathology international

authors： Tsuda H,Tani Y,Hasegawa T,Fukutomi T

更新日期：2001-01-01 00:00:00

abstract：:Pulmonary alveolar proteinosis (PAP) is a rare condition in which pulmonary macrophages fail to clear surfactant, resulting in the alveolar accumulation of lipoproteinaceous debris. The histopathology of PAP is typified by diffuse filling of terminal airways with eosinophilic, PAS/diastase (PAS/D)-positive acellular m...

journal_title：Pathology international

authors： Nishino M,Medoff BD,Mark EJ,Matsubara O,O'Donnell WJ,Currier PF,Kradin RL

更新日期：2011-09-01 00:00:00

abstract：:Although mucinous carcinoma (MC) of the breast is considered to originate from ductal carcinoma, it is not known whether mucinous growth begins in the intraductal carcinoma or later in the invasive carcinoma. In this study, 33 MC (16 pure without any ductal components, 10 mixed Type I with an intraductal component, se...

journal_title：Pathology international

authors： Kato N,Endo Y,Tamura G,Katayama Y,Motoyama T

更新日期：1999-11-01 00:00:00

abstract：:Pleomorphic lobular carcinoma (PLC) of the breast is a variant of lobular carcinoma, characterized by loss of E-cadherin expression and high-grade morphologies. Whether the pathogenesis of PLC is in the ductal or the lobular lineage has been discussed. In this report, a case of PLC combined with apocrine carcinoma is ...

journal_title：Pathology international

authors： Ishii A,Oishi T,Kakuda Y,Yasui H,Kawata T,Muramatsu K,Takahashi K,Sugino T

更新日期：2019-05-01 00:00:00

abstract：:A rare case of a macrofollicular variant of papillary thyroid carcinoma occurring in an 18-year-old male is described. The extirpated tumor, 5.5 x 5.5 x 3.5 cm in size, was well demarcated and multinodular, and histopathologically showed a predominantly macrofollicular structure reminiscent of adenomatous goiter or ma...

journal_title：Pathology international

authors： Nakamura T,Moriyama S,Nariya S,Sano K,Shirota H,Kato R

更新日期：1998-06-01 00:00:00

abstract：:Stenosing flexor tenosynovitis, trigger finger, is a common clinical disorder causing painful locking or contracture of the involved digits, and most instances are idiopathic. This problem is generally caused by a size mismatch between the swollen flexor tendon and the thickened first annular pulley. Although hypertro...

journal_title：Pathology international

authors： Uchihashi K,Tsuruta T,Mine H,Aoki S,Nishijima-Matsunobu A,Yamamoto M,Kuraoka A,Toda S

更新日期：2014-06-01 00:00:00

abstract：:We report a rare case of hepatocellular carcinoma (HCC) with an unusual neuroendocrine component. During a follow-up study for chronic hepatitis C in a 71-year-old man, a nodular lesion showed rapid growth from 1 cm to 4 cm in diameter within 3 months. Histologically, the tumor was consistent with moderately different...

journal_title：Pathology international

authors： Yamaguchi R,Nakashima O,Ogata T,Hanada K,Kumabe T,Kojiro M

更新日期：2004-11-01 00:00:00

abstract：:Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare, recently recognized neoplasm occurring predominantly in the subcutaneous tissue of the lower limbs of adults. We report a case of PHAT in an 83-year-old woman who presented with a 5.0 x 5.0 x 2.0 cm mass in the soft part of her left thigh. Histologically, the...

journal_title：Pathology international

authors： Matsumoto K,Yamamoto T

更新日期：2002-10-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) with TP63 rearrangement is a new entity and has the most dismal prognosis in all types of ALCL. This might be due to the resulting fusion protein having N-terminal truncated p63 with high oncogenic ability. Since this N-terminal domain has the function of tumor suppressor activity...

journal_title：Pathology international

authors： Yamashita T,Higashi M,Kawano R,Momose S,Tokuhira M,Kizaki M,Tamaru JI

更新日期：2019-03-01 00:00:00

abstract：:A 35-year-old Japanese man who had experienced hoarseness for 10 years presented with a vocal cord lesion. A gross examination revealed a left vocal cord polyp occupying two-thirds of the vocal space. The endoscopically resected lesion contained scattered atypical fibroblastic, stellate, or ganglion-like cells with mu...

journal_title：Pathology international

authors： Yorita K,Togashi Y,Nakagawa H,Miyazaki K,Sakata S,Baba S,Takeuchi K,Hayashi Y,Murakami I,Kuroda N,Oda Y,Kohashi K,Yamada Y,Kiyozawa D,Michal M,Michal M

更新日期：2019-06-01 00:00:00

abstract：:A 56-year-old male treated for a gastric yolk sac tumor with an adenocarcinomatous component is described. A mixed area of reticular and glandular neoplastic components was morphologically identified in this tumor. Immunohistochemically, the yolk sac tumor expressed alpha-fetoprotein (AFP), placental alkaline phosphat...

journal_title：Pathology international

authors： Suzuki T,Kimura N,Shizawa S,Yabuki N,Yamaki T,Sasano H,Nagura H

更新日期：1999-06-01 00:00:00

abstract：:The clinicopathological significance of colonic and small-intestinal phenotypes has hitherto remained unclear in gastric cancers. The purpose of the present study was therefore to examine 86 gastric carcinomas histologically and phenotypically using several phenotypic markers, including colon-specific carbonic anhydra...

journal_title：Pathology international

authors： Mizoshita T,Tsukamoto T,Tanaka H,Takenaka Y,Kato S,Cao X,Joh T,Tatematsu M

更新日期：2005-10-01 00:00:00

abstract：:Angiomyolipoma (AML) is a mixed mesenchymal tumor belonging to the family of perivascular epithelioid cell tumors. Concurrent development of AML and adult renal cell carcinoma (RCC) is very rare. Herein is presented a unique case in which RCC arose within a previously detected AML tumor mass. A 40-year-old woman had b...

journal_title：Pathology international

authors： Inomoto C,Umemura S,Sasaki Y,Yasuda M,Terachi T,Osamura RY

更新日期：2007-03-01 00:00:00

abstract：:Anomalous pancreaticobiliary junction (APBJ) is a congenital anomaly in which the pancreatic duct joins the common bile duct proximal to the sphincter of Oddi. Anatomical and immunohistochemical examination of the pancreas with APBJ has rarely been performed. A 72-year-old woman with gallbladder cancer and APBJ died o...

journal_title：Pathology international

authors： Tadokoro H,Takase M,Nobukawa B

更新日期：2008-08-01 00:00:00