Abstract:
:The purpose of the present study was to investigate the relationship between plasma carnitine concentration and body composition variation in relation to muscular and fat masses since there is no experimentally proved correlation between plasma carnitine and body masses. We used bioelectric impedance analysis (BIA), to determine body composition and to have a complete physical fitness evaluation. The post-absorptive plasma free carnitine and acetyl carnitine plasma levels, body composition as Fat-Free Mass (FFM) and Fat Mass (FM) in kg, as well as in percent of body mass, were analysed in 33 healthy subjects. A significant negative correlation was found between plasma acetyl carnitine and FFM in weight (kg) as well as in percent of body mass (respectively p < 0.0001; p < 0.01); a significant positive correlation was found only between FM in percent and plasma acetyl carnitine (p < 0.01). The observed negative correlation between plasma acetyl carnitine and muscular mass variation might reflect an oxidative metabolic muscle improvement in relation to muscular fat free mass increment and might be evidence that muscle metabolism change is in relation to plasma acetyl carnitine concentration.
journal_name
Amino Acidsjournal_title
Amino acidsauthors
Gatti R,De Palo CB,Spinella P,De Palo EFdoi
10.1007/BF01318855subject
Has Abstractpub_date
1998-01-01 00:00:00pages
361-9issue
4eissn
0939-4451issn
1438-2199journal_volume
14pub_type
杂志文章相关文献
AMINO ACIDS文献大全abstract::A simple and efficient one-pot procedure that enables rapid access to orthogonally protected N,N'-diaminoalkylated basic amino acid building blocks fully compatible with standard Boc and Fmoc solid-phase peptide synthesis is reported. Described synthetic approach includes double reductive alkylation of N (α)-protected...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-012-1336-5
更新日期:2013-02-01 00:00:00
abstract::Antimicrobial peptides (AMPs) constitute a diverse class of naturally occurring or synthetic antimicrobial molecules that have potential for use in the treatment of drug-resistant infections. Several undesirable properties of AMPs, however, may ultimately hinder their development as antimicrobial agents. Thus, new syn...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-014-1761-8
更新日期:2014-09-01 00:00:00
abstract::Alterations in adipocyte characteristics are highly implicated in the pathology of obesity. In a recent article, we demonstrated that high-fat diet-induced obesity impairs lysosomal function, thereby suppressing autophagy in mice white adipose tissue. Taurine, an amino acid naturally contained in the normal diet and e...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-018-2550-6
更新日期:2018-05-01 00:00:00
abstract::Mice over-expressing the creatine transporter have elevated myocardial creatine levels [Cr] and are protected against ischaemia/reperfusion injury via improved energy reserve. However, mice with very high [Cr] develop cardiac hypertrophy and dysfunction. To investigate these contrasting effects, we applied a non-biase...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-016-2236-x
更新日期:2016-08-01 00:00:00
abstract::The present research has been carried out to elicit the mechanism of antiangiogenic activity of a fusion peptide P2. Peptide P2 was designed by the connection of a heptapeptide MMP inhibitor to ES-2, a fragment of Endostatin. In a previous study, P2 demonstrated strong antiangiogenic and antitumor effect, and the curr...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-018-2589-4
更新日期:2018-08-01 00:00:00
abstract::Interferon tau (IFNT) was discovered as the pregnancy recognition signal in ruminants, but is now known to have a plethora of physiological functions in the mammalian uterus. The mammalian uterus includes, from the outer surface to the lumen, the serosa, myometrium and endometrium. The endometrium consists of the lumi...
journal_title:Amino acids
pub_type: 杂志文章,评审
doi:10.1007/s00726-014-1905-x
更新日期:2015-03-01 00:00:00
abstract::Two novel cyclic hexapeptides, designated NW-G10 (1) and NW-G11 (2), were isolated from the fermentation broth of Streptomyces alboflavus 313. Their relative structures were elucidated on the basis of extensive spectroscopic analysis, and the absolute configurations of several constituent amino acids were determined b...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-012-1303-1
更新日期:2012-11-01 00:00:00
abstract::The human immunodeficiency virus type 1 (HIV-1) transactivator of transcription (TAT) protein, a member of the protein transduction domain (PTD) superfamily, can deliver heterologous proteins across most biomembranes without losing bioactivity. However, there is no report on whether the TAT core domain containing the ...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-010-0534-2
更新日期:2010-08-01 00:00:00
abstract::Proline dehydrogenase/oxidase (PRODH/POX) is a mitochondrial protein critical to multiple stress pathways. Because of the roles of PRODH/POX in signaling, and its shared localization to the mitochondrial inner membrane with the electron transport chain (ETC), we investigated whether there was a direct relationship bet...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-015-2134-7
更新日期:2016-03-01 00:00:00
abstract::Rats were trained to perform a conditioned avoidance response to white noise in a conventional two-compartment "shuttle-box". The partition between the compartments had two openings, however, and the correct passage (leftor right) was signalled by changes in background illumination. In this situation the psychotomimet...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/BF00806009
更新日期:1992-02-01 00:00:00
abstract::The role of pH-dependent ionic structures of L-amino acids in catalysis has been investigated for the two-component Mannich reactions between dimethyl malonate (DMM)/ethyl acetoacetate (EAA) and imines. As catalysts, L-amino acids performed well, even better than corresponding base catalysts and provided the β-amino c...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-019-02798-z
更新日期:2019-11-01 00:00:00
abstract::Amino acid and glucosinolate biosynthesis are two interdependent pathways; amino acid synthesis as a part of primary metabolism provides the precursors for glucosinolate biosynthesis in secondary metabolism. In our previous studies, the combination of coexpression analysis and metabolite profiling led to the identific...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-010-0681-5
更新日期:2010-10-01 00:00:00
abstract::Taurine (TAU) has been shown to improve exercise time to exhaustion and 3-km running performance; however, no studies have considered the effect of acute TAU ingestion on short duration cycling time trial (TT) performance. The aim of this study was to determine the effects of a single oral acute dose of 1000 mg of TAU...
journal_title:Amino acids
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00726-016-2282-4
更新日期:2016-11-01 00:00:00
abstract::The dipeptide carnosine is found in high concentrations in human skeletal muscle and shows large inter-individual differences. Sex and age are determining factors, however, systematic studies investigating the sex effects on muscle carnosine content throughout the human lifespan are lacking. Despite the large inter-in...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-011-1197-3
更新日期:2012-07-01 00:00:00
abstract::Cell-penetrating peptides, a group of short peptides, can traverse cell membranes to enter cells and thus facilitate the uptake of various molecular cargoes. Thus, they have the potential to become powerful drug delivery systems. The correct identification of peptides as cell-penetrating or non-cell-penetrating would ...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-015-1974-5
更新日期:2015-07-01 00:00:00
abstract::The enhancing effect on the water structure has been confirmed for most of the osmolytes exhibiting both stabilizing and destabilizing properties in regard to proteins. The presented work concerns osmolytes, which should be classified as "structure breaking" solutes: taurine and N,N,N-trimethyltaurine (TMT). Here, we ...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-017-2499-x
更新日期:2018-01-01 00:00:00
abstract::Among the large family of cyclodepsipeptides, the simplest members are the cyclodidepsipeptides which have an ester group and an amide group in the same six-membered ring. To point out the pharmacological potential of this class of compounds, the present article reviews structure, isolation, synthesis and biological p...
journal_title:Amino acids
pub_type: 杂志文章,评审
doi:10.1007/s00726-014-1666-6
更新日期:2014-04-01 00:00:00
abstract::Nitric oxide (NO) is a free radical gas synthesised from arginine and oxygen by enzymes of the family of the nitric oxide synthase. In particular, the neuronal nitric oxide synthase (nNOS) is highly expressed by cells of the hypothalamic paraventricular nucleus, where the sympatho-adrenal system, the hypothalamic-pitu...
journal_title:Amino acids
pub_type: 杂志文章,评审
doi:10.1007/s00726-007-0630-0
更新日期:2008-06-01 00:00:00
abstract::Taking a minimalistic approach in efforts to lower the cost for the development of new synthetic antimicrobial peptides, ultrashort cationic lipopeptides were designed to mimic the amphiphilic nature crucial for their activity but with only a very short peptide sequence ligated to a lipidic acid. Nine ultrashort catio...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-014-1806-z
更新日期:2014-11-01 00:00:00
abstract::Interplay between proteins, nucleic acids, carbohydrates and/or lipids is involved in almost every process in life on earth. As a consequence, a wide range of diseases results from abnormal interactions of such biomolecules. The main motivation of foldamer science is the development of scaffolds that are capable of ad...
journal_title:Amino acids
pub_type: 杂志文章,评审
doi:10.1007/s00726-011-0894-2
更新日期:2011-08-01 00:00:00
abstract::L-tryptophan (TRP) is the precursor amino acid for the synthesis of serotonin (5-HT). 5-HT is effective both on the food intake and gastrointestinal system contractility. The aim of this study was to search the effects of systemic TRP treatment on 5-HT levels of ileum and searching the effect of ileal contractility an...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-006-0339-5
更新日期:2007-01-01 00:00:00
abstract::Agmatine, a metabolite generated by arginine decarboxylation, has been reported as neuromodulator and neuroactive substance. Several findings suggest that agmatine displays neuroprotective effects in several models of neurodegenerative disorders, such as Parkinson's disease (PD). It has been hypothesized that biogenic...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-019-02759-6
更新日期:2020-02-01 00:00:00
abstract::Taurine and glutamate were monitored by microdialysis technique during various cerebral insults: a. Application of K+ triggered a cortical spreading depression (CSD). Taurine and glutamate increased concomitantly but recovery of glutamate was faster than that of taurine. b. Application of NMDA induced also CSD but onl...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s007260070007
更新日期:2000-01-01 00:00:00
abstract::A subline growing in medium without arginine and ornithine was established from a rat Reuber hepatoma cell line (R-Y121B·cho). The subline designated R-Y117B·cho was able to grow in glutamine, arginine and ornithine-free, glutamate-supplemented medium. Arginine synthesis from glutamate requires four urea cycle enzymes...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/BF00807328
更新日期:1996-09-01 00:00:00
abstract::N-Acetyl-AA(amino acid)-NHtBu derivatives of all 20 naturally occurring amino acids have been synthesized. Syntheses were performed via solution-phase methodology with yields that allow for access to gram quantities of substrates, in most cases. Syntheses include the coupling of a hindered amine, tert-butylamine, with...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-009-0279-y
更新日期:2010-03-01 00:00:00
abstract::L-Homoarginine is a cationic amino acid derivative, which is structurally related to L-arginine and lysine. Several lines of evidence point to nervous tissue as an important target of homoarginine action. In the mammalian brain homoarginine can be detected in noticeable quantities, but its origin is currently poorly e...
journal_title:Amino acids
pub_type: 杂志文章,评审
doi:10.1007/s00726-015-1960-y
更新日期:2015-09-01 00:00:00
abstract::N-[(Z)-N-Benzoyl- or N-boc-(2-fluorophenyl)dehydroalanyl]-(R)- or (S)-phenyl-alanines 1,2,5 and 6 were hydrogenated in the presence of chiral and achiral rhodium complexes. The optical induction is compared to the results obtained using the corresponding esters as substrates. ...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s007260200018
更新日期:2002-06-01 00:00:00
abstract::The putative translation factor eIF5A is essential for cell viability and is highly conserved from archaebacteria to mammals. This factor is the only cellular protein that undergoes an essential posttranslational modification dependent on the polyamine spermidine, called hypusination. This review focuses on the functi...
journal_title:Amino acids
pub_type: 杂志文章,评审
doi:10.1007/s00726-007-0533-0
更新日期:2007-08-01 00:00:00
abstract::Chemically defined amino acid diets have been developed for most laboratory and meat-producing animal species as well as for humans. In many cases, growth performance of animals fed these diets equals that obtained with standard intact-protein diets. The pattern of both essential and nonessential amino acids is critic...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/BF00806073
更新日期:1992-02-01 00:00:00
abstract::A novel type I ribosome-inactivating protein (RIP), designated as curcin C, was purified from Jatropha curcas, an important feedback source of bio-fuel. Molecular mass and isoelectric point of curcin C were 31.398 kDa and 7.12 as detected by MALTI-TOF assay and capillary electrophoresis assay, respectively. N-terminal...
journal_title:Amino acids
pub_type: 杂志文章
doi:10.1007/s00726-017-2456-8
更新日期:2017-09-01 00:00:00