The effect of acute taurine ingestion on 4-km time trial performance in trained cyclists.

abstract：:Extracellular peptide ligand binding sites, which bind the N-termini of angiotensin II (AngII) and bradykinin (BK) peptides, are located on the N-terminal and extracellular loop 3 regions of the AT(1)R and BKRB(1) or BKRB(2) G-protein-coupled receptors (GPCRs). Here we synthesized peptides P15 and P13 corresponding to...

journal_title：Amino acids

authors： Lopes DD,Vieira RF,Malavolta L,Poletti EF,Shimuta SI,Paiva AC,Schreier S,Oliveira L,Nakaie CR

更新日期：2013-03-01 00:00:00

abstract：:Regulated proteolysis plays important roles in cell biology and pathological conditions. A crosstalk exists between apoptosis and the ubiquitin-proteasome system, two pathways responsible for regulated proteolysis executed by different proteases. To investigate whether the apoptotic process also affects the 20S protea...

journal_title：Amino acids

authors： Schmidt F,Dahlmann B,Hustoft HK,Koehler CJ,Strozynski M,Kloss A,Zimny-Arndt U,Jungblut PR,Thiede B

更新日期：2011-07-01 00:00:00

abstract：:In this review, recent studies on the electrophysiological effects of de novo synthesized ("endogenous") kynurenic acid (KYNA) are discussed. Endogenous KYNA is normally formed as a byproduct of tryptophan metabolism. Evidence for a physiological role in neuronal excitability has not been strong, in part because brain...

journal_title：Amino acids

authors： Scharfman HE,Goodman JH,Schwarcz R

更新日期：2000-01-01 00:00:00

abstract：:The mitochondrial branched chain aminotransferase-deficient mouse model (BCATm KO), which exhibits elevated plasma and tissue branched chain amino acids (BCAAs), was used to study the effect of BCAAs on mammalian target of rapamycin complex 1 (mTORC1) regulation of organ size. BCATm is the first enzyme in the BCAA cat...

journal_title：Amino acids

authors： Neishabouri SH,Hutson SM,Davoodi J

更新日期：2015-06-01 00:00:00

abstract：:Functionalized collagen-mimetic peptides (CMPs) have been widely used in the preparation of collagen-related biomaterials. Among the reported results, the induced noncovalent interactions between the implanted functional groups or moieties were frequently the key elements to promote the self-assembly of small CMPs. In...

journal_title：Amino acids

authors： Huang PW,Chang JM,Horng JC

更新日期：2016-12-01 00:00:00

abstract：:The study of nanomaterial/biomolecule interface is an important emerging field in bionanoscience, and additionally in many biological processes such as hard-tissue growth and cell-surface adhesion. To have a deeper understanding of the amino acids/gold nanoparticle assemblies, the adsorption of these amino acids on th...

journal_title：Amino acids

authors： Ramezani F,Amanlou M,Rafii-Tabar H

更新日期：2014-04-01 00:00:00

abstract：:The increased protein requirement of endurance athletes may be related to the need to replace exercise-induced oxidative losses, especially of the branched-chain amino acids (BCAA). However, it is unknown if non-essential amino acids (NEAA) influence the requirement for essential amino acids (EAA) during post-exercise...

journal_title：Amino acids

authors： Kato H,Volterman KA,West DWD,Suzuki K,Moore DR

更新日期：2018-12-01 00:00:00

abstract：:Polyamines are small organic polycations essential for cell proliferation and survival. Antizymes (AZs) are small proteins regulated by polyamines that inhibit polyamine biosynthesis and uptake in mammalian cells. In addition, antizyme functions are also regulated by antizyme inhibitors, homologue proteins of ornithin...

journal_title：Amino acids

authors： López-Contreras AJ,Ramos-Molina B,Cremades A,Peñafiel R

更新日期：2010-02-01 00:00:00

abstract：:Several new beta,beta-dihalo and beta-halo-beta-substituted dehydroalanines and dehydrodipeptides were synthesized by reacting the corresponding dehydroamino acid derivative with a N-halosuccinimide or in the case of beta,beta-di-iododehydroalanines with iodine. The results obtained confirmed that the stereochemical o...

journal_title：Amino acids

authors： Ferreira PM,Monteiro LS,Pereira G

更新日期：2010-07-01 00:00:00

abstract：:Oxidative stress, an excess of reactive oxygen species (ROS), may lead to oxidative post-translational modifications of proteins resulting in the cleavage of the peptide backbone, known as α-amidation, and formation of fragments such as peptide amides and α-ketoacyl peptides (α-KaP). In this study, we first compared d...

journal_title：Amino acids

authors： Sajapin J,Hellwig M

更新日期：2020-10-01 00:00:00

abstract：:Polyamines are essential for proliferation of endothelial cells (EC) and angiogenesis. This study was conducted to identify the metabolic source(s) of ornithine for polyamine synthesis in EC, using N(ω)-hydroxy-nor-L-arginine (Nor-NOHA, an inhibitor of arginase) and gabaculine (an inhibitor of ornithine aminotransfera...

journal_title：Amino acids

authors： Li H,Meininger CJ,Bazer FW,Wu G

更新日期：2016-10-01 00:00:00

abstract：:The enzymes Akt, mTOR, p70(S6K), rpS6, GSK3, and glycogen synthase interact in the control of protein and/or glycogen synthesis in skeletal muscle, and each has been found to respond to exercise and nutrient supplementation. In the present study, we tested the hypothesis that nutrient supplementation post exercise, in...

journal_title：Amino acids

authors： Ivy JL,Ding Z,Hwang H,Cialdella-Kam LC,Morrison PJ

更新日期：2008-06-01 00:00:00

abstract：:N-[(Z)-N-Benzoyl- or N-boc-(2-fluorophenyl)dehydroalanyl]-(R)- or (S)-phenyl-alanines 1,2,5 and 6 were hydrogenated in the presence of chiral and achiral rhodium complexes. The optical induction is compared to the results obtained using the corresponding esters as substrates. ...

journal_title：Amino acids

authors： Döbler C,Kreuzfeld HJ,Fischer C,Michalik M

更新日期：2002-06-01 00:00:00

abstract：:Depending on the amount of alimentary proteins, between 6 and 18 g nitrogenous material per day enter the large intestine lumen through the ileocaecal junction. This material is used as substrates by the flora resulting eventually in the presence of a complex mixture of metabolites including ammonia, hydrogen sulfide,...

journal_title：Amino acids

authors： Blachier F,Mariotti F,Huneau JF,Tomé D

更新日期：2007-11-01 00:00:00

abstract：:This study determined whether N-acetylcysteine (NAC) could affect intestinal redox status, proinflammatory cytokines, epidermal growth factor (EGF), EGF receptor (EGFR), Toll-like receptor-4 (TLR4), and aquaporin-8 in a lipopolysaccharide (LPS)-challenged piglet model. Eighteen piglets (35-day-old) were randomly alloc...

journal_title：Amino acids

authors： Hou Y,Wang L,Yi D,Ding B,Yang Z,Li J,Chen X,Qiu Y,Wu G

更新日期：2013-09-01 00:00:00

abstract：:Glutamine is the most abundant amino acid in the body. It is an important fuel for some key cells of the immune system. Both the plasma concentration of glutamine and the functional ability of immune cells in the blood are decreased after prolonged, exhaustive exercise. Glutamine feeding has had beneficial effects in ...

journal_title：Amino acids

authors： Castell LM,Newsholme EA

更新日期：2001-01-01 00:00:00

abstract：:Obesity, type 2 diabetes (T2DM) and cardiovascular disease (CVD) are the most common preventable causes of morbidity and mortality worldwide. They represent major public health threat to our society. Increasing prevalence of obesity and T2DM contributes to escalating morbidity and mortality from CVD and stroke. Carnos...

journal_title：Amino acids

authors： Baye E,Ukropcova B,Ukropec J,Hipkiss A,Aldini G,de Courten B

更新日期：2016-05-01 00:00:00

abstract：:Hippocampus trimaculatus is one of the most heavily traded seahorse species for traditional medicine purposes in many countries. In the present study, we showed neuroprotective effects of peptide derived from H. trimaculatus against amyloid-β42 (Aβ42) toxicity which are central to the pathogenesis of Alzheimer's disea...

journal_title：Amino acids

authors： Pangestuti R,Ryu B,Himaya S,Kim SK

更新日期：2013-08-01 00:00:00

abstract：:Involvement of individual antioxidant proteins (AOXP) and antioxidants in the differentiation process has been already reported. A systematic search strategy for detecting differentially regulated AOXP in neuronal differentiation, however, has not been published so far. The aim of this study was to provide an analytic...

journal_title：Amino acids

authors： Oh JE,Karlmark Raja K,Shin JH,Hengstschläger M,Pollak A,Lubec G

更新日期：2005-11-01 00:00:00

abstract：:The relationship between taurine concentrations of plasma, whole blood, serum and skeletal muscle during taurine depletion and repletion was investigated in cats, to identify the most useful indicators of taurine status. Sixteen cats were fed a purified diet containing either 0 or 0.15 g/kg taurine for 5 months. Treat...

journal_title：Amino acids

authors： Pacioretty L,Hickman MA,Morris JG,Rogers QR

更新日期：2001-12-01 00:00:00

abstract：:The high efficiency of protein deposition during the neonatal period is driven by high rates of protein synthesis, which are maximally stimulated after feeding. In the current study, we examined the individual roles of amino acids and insulin in the regulation of protein synthesis in peripheral and visceral tissues of...

journal_title：Amino acids

authors： Suryawan A,O'Connor PM,Bush JA,Nguyen HV,Davis TA

更新日期：2009-05-01 00:00:00

abstract：:The efficient synthesis ofδ-hydroxy-β,γ-dehydroα-amino acids (1) was achieved by the hybrid process, in which the Pd(II)-assisted rear-rangement ofβ-acetoxyallylglycine ester (6) afforded the corresponding (E)-δ-acetoxyvinylglycine derivatives (7) in a moderate yield. The chemo- and stereo-selective hydrolysis of7 was...

journal_title：Amino acids

authors： Kirihata M,Fukuari M,Izukawa T,Ichimoto I

更新日期：1995-12-01 00:00:00

abstract：:Glutamate dehydrogenase (GDH) plays a crucial role in amino acid deamination and has been used as an inductor of nutrients metabolism. In this study, we cloned and analyzed the GDH cDNAs in diploids (red crucian carp), triploids and tetraploids and characterized their expression profiles upon dietary treatments. Resul...

journal_title：Amino acids

authors： Liu Z,Zhou Y,Liu S,Zhong H,Zhang C,kang X,Liu Y

更新日期：2012-12-01 00:00:00

abstract：:Enzymes are the most versatile molecules in the biological world. These amazing molecules play an integral role in the regulation of various metabolic pathways and physiology subsequently. Promiscuity of an enzyme is the capacity to catalyze additional biochemical reactions besides their native one. Catalytic promiscu...

journal_title：Amino acids

authors： Verma MK,Pulicherla KK

更新日期：2016-04-01 00:00:00

abstract：:Alterations in adipocyte characteristics are highly implicated in the pathology of obesity. In a recent article, we demonstrated that high-fat diet-induced obesity impairs lysosomal function, thereby suppressing autophagy in mice white adipose tissue. Taurine, an amino acid naturally contained in the normal diet and e...

journal_title：Amino acids

authors： Kaneko H,Kobayashi M,Mizunoe Y,Yoshida M,Yasukawa H,Hoshino S,Itagawa R,Furuichi T,Okita N,Sudo Y,Imae M,Higami Y

更新日期：2018-05-01 00:00:00

abstract：:The objective of this study was to determine the dose as well as duration of exposure-dependent effects of L-alanyl-L-glutamine, arginine or taurine on polymorphonuclear neutrophil (PMN) free alpha-keto acid profiles and, in a parallel study, on PMN immune functions. Exogenous L-alanyl-L-glutamine significantly increa...

journal_title：Amino acids

authors： Mühling J,Nickolaus KA,Halabi M,Fuchs M,Krüll M,Engel J,Wolff M,Matejec R,Langefeld TW,Welters ID,Menges T,Dehne MG,Sablotzki A,Hempelmann G

更新日期：2005-11-01 00:00:00

abstract：:The translation elongation factor eIF5A is conserved through evolution and is necessary to rescue the ribosome during translation elongation of polyproline-containing proteins. Although the site of eIF5A binding to the ribosome is known, no systematic analysis has been performed so far to determine the important resid...

journal_title：Amino acids

authors： Barbosa NM,Boldrin PE,Rossi D,Yamamoto PA,Watanabe TF,Serrão VH,Hershey JW,Fraser CS,Valentini SR,Zanelli CF

更新日期：2016-10-01 00:00:00

abstract：:The unusual basic amino acid, hypusine [N(epsilon)-(4-amino-2-hydroxybutyl)-lysine], is a modified lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. This naturally occurring amino acid is a product of a unique posttranslational modification that occurs in only one cellular protein, euk...

journal_title：Amino acids

authors： Park MH,Nishimura K,Zanelli CF,Valentini SR

更新日期：2010-02-01 00:00:00

abstract：:Glucosinolates are amino acid-derived natural plant products found throughout the Capparales order. Glucosinolates and their degradation products have a wide range of biological activities, e.g. in plant defense as deterrents against insect and fungi. The conversion of amino acids to aldoximes is a key step in glucosi...

journal_title：Amino acids

authors： Mikkelsen MD,Petersen BL,Olsen CE,Halkier BA

更新日期：2002-01-01 00:00:00

abstract：:M33 is a branched peptide currently under preclinical characterization for the development of a new antibacterial drug against gram-negative bacteria. Here, we report its pegylation at the C-terminus of the three-lysine-branching core and the resulting increase in stability to Pseudomonas aeruginosa elastase. This pro...

journal_title：Amino acids

authors： Falciani C,Lozzi L,Scali S,Brunetti J,Bracci L,Pini A

更新日期：2014-05-01 00:00:00