Abstract:
:From a factor analysis of data from a learning experiment evidence is presented which appears to support the Blomfield-Marr thesis that in the learning of motor actions the cerebellum operates by the turning off of incorrect movements rather than by the turning on of correct ones. The factor model employed is that due to Godfrey Thomson which gives a neurostatistical explanation of the origin of mental factors.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Maxwell AEdoi
10.1017/s0033291700018298subject
Has Abstractpub_date
1976-11-01 00:00:00pages
643-8issue
4eissn
0033-2917issn
1469-8978journal_volume
6pub_type
杂志文章abstract::To investigate the relationships between cardiovascular variables (SBP, DBP, and HR) and circulating natural killer (NK) cell numbers, 70 male volunteers were subjected to a rest condition (N = 30) or a stressful laboratory task (N = 40). At baseline, no significant relationships could be demonstrated between the numb...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700036229
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719000618
更新日期:2020-04-01 00:00:00
abstract::The blood counts of 80 patients with depression were examined (50 unipolar, 30 bipolar). Many had reduced numbers of circulating lymphocytes. This abnormality was more common in the unipolar group (52%) than in the bipolar group (27%). When those patients with an abnormal dexamethasone suppression test response in bot...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700024934
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:A number of scales are used to estimate the severity of depression. However, differences between self-report and clinician rating, multi-dimensionality and different weighting of individual symptoms in summed scores may affect the validity of measurement. In this study we examined and integrated the psychome...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707001730
更新日期:2008-02-01 00:00:00
abstract::Data from a general population survey of psychiatric disorder in Camberwell were used to calculate the risk of a CATEGO-defined depressive episode before the age of 65, using a modification of Strömgren's method. Current depression was defined as cases within the relevant categories of the CATEGO program and at thresh...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700012435
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:A review of studies of cognition in the euthymic phase of unipolar and bipolar affective disorder reveals diverging results. METHODS:The study was designed as a controlled cohort study, with the Danish psychiatric case register of admissions used to identify patients and the Danish civil register to identif...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291798006862
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Restrictive food intake in anorexia nervosa (AN) has been related to an overactive cognitive control network inhibiting intuitive motivational responses to food stimuli. However, the influence of short-term homeostatic signaling on the neural regulation of cue-induced food craving in AN is still unclear. ME...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719003970
更新日期:2020-01-14 00:00:00
abstract:BACKGROUND:Belief inflexibility is a thinking style observed in patients with schizophrenia, in which patients tend to refute evidence that runs counter to their prior beliefs. This bias has been related to a dominance of prior expectations (prior beliefs) over incoming sensory evidence. In this study we investigated t...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000384
更新日期:2012-11-01 00:00:00
abstract::Patients diagnosed on the basis of structured interviews as having affective psychoses were less sensitive in detecting the presence of a transient auditory signal than were schizophrenic patients or non-patients. Patients with affective psychoses also benefited more (their reaction time was more reduced) than the oth...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700056622
更新日期:1975-08-01 00:00:00
abstract::The question addressed to in this paper is whether severely mentally ill patients are treated differently in a community mental health service without the back-up of a mental hospital (south-Verona, Italy) compared with an institution-based system in which mental hospitals, although highly modernized, are still predom...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700033754
更新日期:1996-01-01 00:00:00
abstract::Twenty schizophrenic patients with tardive dyskinesia and an equal number of matched controls were tested on a novel cognitive task. The task had two components: cued response and spatial memory. Relative to controls, the dyskinetic subjects showed a superior cued response performance but an equal spatial memory abili...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700023588
更新日期:1985-05-01 00:00:00
abstract::In a prospective cohort study of consecutive primary care attenders in south London, the estimated prevalence of non-psychotic psychiatric disorder was 45.6%, using the Revised Clinical Interview Schedule (CIS-R). The estimated 12-month incidence rate was 15.7%. Extremely high stability was found in CIS-R scores over ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004023
更新日期:1997-01-01 00:00:00
abstract::Post-traumatic stress disorder (PTSD) was studied in the Piedmont region of North Carolina. Among 2985 subjects, the lifetime and six month prevalence figures for PTSD were 1.30 and 0.44% respectively. In comparison to non-PTSD subjects, those with PTSD had significantly greater job instability, family history of psyc...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700022352
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:Although numerous studies have examined the latent structure of major depression, less attention has focused on mania. This paper presents the first investigation outside the USA to evaluate the psychometric properties of the DSM-IV criterion B mania symptoms using item response theory (IRT). METHOD:Data we...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000980
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Studies investigating early developmental factors in relation to psychopathology have mainly focused on schizophrenia. The personality dimension of neuroticism seems to be a general risk factor for psychopathology, but evidence on associations between early developmental precursors and personality traits is ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712001997
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Little is known about the mental health of partners of survivors of high levels of trauma in post-conflict countries. METHOD:We studied 677 spouse dyads (n = 1354) drawn from a community survey (response 82.4%) in post-conflict Timor-Leste. We used culturally adapted measures of post-traumatic stress disord...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716002233
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797006405
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Although a substantial body of research points to a link between psychological distress and inflammatory responses in middle-aged and older adults, particularly those with cardiovascular disease, the relationship between inflammation and distress in young, healthy individuals has not been established. This s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710000267
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:White matter (WM) impairments have been reported in patients with bipolar disorder (BD) and those at high familial risk of developing BD. However, the distribution of these impairments has not been well characterized. Few studies have examined WM integrity in young people early in the course of illness and i...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716001161
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:This study examined the associations between accelerometer-derived sedentary time (ST), lower intensity physical activity (LPA), higher intensity physical activity (HPA) and the incidence of depressive symptoms over 4 years of follow-up. METHODS:We included 2082 participants from The Maastricht Study (mean ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004924
更新日期:2020-12-18 00:00:00
abstract:BACKGROUND:A few previous studies suggest that a large number of individuals do not present at hospital following a suicide attempt, complicating recurrence prevention and prevalence estimation. METHODS:Data were extracted from a regular phone survey in representative samples of the French population aged 18-75 years ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720002305
更新日期:2020-07-03 00:00:00
abstract:BACKGROUND:Studies evaluating depression's role in lung cancer risk revealed contradictory findings, partly because of the small number of cases, short follow-up periods, and failure to account for key covariates including smoking exposure. We investigated the association of depressive symptoms with lung cancer risk in...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004390
更新日期:2020-12-03 00:00:00
abstract:BACKGROUND:Mental disorders often begin during the formative years of education. They may disrupt education and lead to social underachievement. METHODS:We examined the impact of mental disorders treated in hospital (ages 16-29) on educational attainment up to 31 years in the Northern Finland 1966 Birth Cohort (N = 10...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170100304x
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:In the present paper, sex differences in the association between adult depression and childhood experiences were examined. METHODS:The study series of the Finnish UKKI Study consisted of a population sample of 501 men and 499 women. Information concerning childhood experiences was gathered retrospectively i...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797006089
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate a programme of lesion surgery carried out on patients with treatment-resistant depression (TRD). METHOD:This was a retrospective study looking at clinical and psychometric data from 45 patients with TRD who had undergone bilateral stereotactic anterior capsulotomy s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716003159
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:The rate of binocular rivalry has been reported to be slower in subjects with bipolar disorder than in controls when tested with drifting, vertical and horizontal gratings of high spatial frequency. METHOD:Here we assess the rate of binocular rivalry with stationary, vertical and horizontal gratings of low ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291703007475
更新日期:2003-05-01 00:00:00
abstract:INTRODUCTION:Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a possible alternative to electroconvulsive therapy for the treatment of selected patients with depression, bipolar affective disorder and schizophrenia. The aim of this study was to evaluate the evidence for the effectiveness of rTMS...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s0033291701004378
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Differences between verbal and non-verbal cognitive development from childhood to adulthood may differentiate between those with and without psychotic symptoms and affective symptoms in later life. However, there has been no study exploring this in a population-based cohort. METHOD:The sample was drawn from...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000393
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Depression is associated with alterations of emotional and cognitive processing, and executive control in particular. Previous research has shown that depressed patients are impaired in their ability to shift attention from one emotional category to another, but whether this shifting deficit is more evident ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002418
更新日期:2012-07-01 00:00:00
abstract::Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-pickin...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700030373
更新日期:1992-05-01 00:00:00