Abstract:
:To investigate the relationships between cardiovascular variables (SBP, DBP, and HR) and circulating natural killer (NK) cell numbers, 70 male volunteers were subjected to a rest condition (N = 30) or a stressful laboratory task (N = 40). At baseline, no significant relationships could be demonstrated between the number of NK cells and the cardiovascular variables. Analysis of covariance showed that the stressor induced increases in the number of NK cells, SBP, DBP, and HR. Changes in Nk cell numbers were highly correlated to changes in cardiovascular variables in both the task and the no-task group. These results indicate that there is no relationship between the number of circulating NK cells and cardiovascular levels per se, but that changes in these variables, either stress-induced or under rest conditions, are regulated by a common mechanism.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Benschop RJ,Godaert GL,Geenen R,Brosschot JF,De Smet MB,Olff M,Heijnen CJ,Ballieux REdoi
10.1017/s0033291700036229subject
Has Abstractpub_date
1995-03-01 00:00:00pages
323-7issue
2eissn
0033-2917issn
1469-8978journal_volume
25pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:There is uncertainty about the incidence of breakthrough psychosis in treatment adherent patients, and the role that factors, such as cumulative antipsychotic exposure, play in this phenomenon. METHODS:In a nationwide cohort of individuals treated for schizophrenia-spectrum disorders in Finland between 1 Ja...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001296
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Frequency and quantity of alcohol consumption are metrics commonly used to measure alcohol consumption behaviors. Epidemiological studies indicate that these alcohol consumption measures are differentially associated with (mental) health outcomes and socioeconomic status (SES). The current study aims to eluc...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719000357
更新日期:2020-02-01 00:00:00
abstract::A two-stage psychiatric survey of a random samples of adults aged 18-64 from Camberwell is described. Agency interviewers carried out the first stage (N = 800), using the shorter form of the Present State Examination (PSE). MRC interviewers, using the full PSE, saw a stratified sample of these (N = 310) in the second ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700052879
更新日期:1981-08-01 00:00:00
abstract::The effects of physostigmine on test performance of a patient with multiple cognitive deficits were observed in a double-blind, placebo-controlled study. Scores on tests of learning and memory and tests of visuo-spatial and constructional ability were both improved by physostigmine, while lecithin improved scores only...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700024867
更新日期:1987-05-01 00:00:00
abstract::A monotonous voice is produced by schizophrenic patients whose expression of emotion is damped down and by patients with a severe degree of depression. Clinically, the distinction between these two diagnostic entities is virtually impossible to establish auditorily on the basis of voice quality alone. The laryngograph...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700041349
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:In the present paper, sex differences in the association between adult depression and childhood experiences were examined. METHODS:The study series of the Finnish UKKI Study consisted of a population sample of 501 men and 499 women. Information concerning childhood experiences was gathered retrospectively i...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797006089
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics. ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719004008
更新日期:2020-02-03 00:00:00
abstract:BACKGROUNDS:Cigarette smoking is strongly associated with major depressive disorder (MDD). However, any genetic etiology of such comorbidity and causal relations is poorly understood, especially at the genome-wide level. METHODS:In the present in silico research, we analyzed summary data from the genome-wide associati...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329172000063X
更新日期:2020-04-06 00:00:00
abstract::Cholecystokinin (CCK) is a peptide originally isolated from the gut. It has been investigated as a candidate treatment for schizophrenia on the assumption that the illness is associated with an imbalance between CCK and dopamine in the mesolimbic dopamine system. Many of the studies to assess the efficacy of CCK used ...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,评审
doi:10.1017/s0033291700008278
更新日期:1988-08-01 00:00:00
abstract::Changes in the erythrocyte membrane cation carrier following lithium ingestion in normal human subjects were studied; ouabain sensitive potassium influx fell significantly during the lithium treated phase. Lithium was fed to rats and no change in erythrocyte Na-K ATPase was shown. These findings contrast with studies ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700029305
更新日期:1977-05-01 00:00:00
abstract::The variations in suicide mortality in England and Wales over a 100-year period (1876-1975) are explained by the development of a descriptive model. The model used in a stepwise linear regression using 5 variables including toxic gas production. The variables give a good description of the observed changes in suicide ...
journal_title:Psychological medicine
pub_type: 历史文章,杂志文章
doi:10.1017/s003329170005217x
更新日期:1981-05-01 00:00:00
abstract::Recent literature on insight has paid little attention to patients' social backgrounds and cultures. Discharge summaries from 357 patients with a psychotic illness were examined to investigate factors associated with insight. A highly significant association was found between British white ethnic origin and being thou...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700035406
更新日期:1996-09-01 00:00:00
abstract::The Social Behaviour Schedule (SBS) was examined as a measure of disability in a series of 66 chronic psychiatric patients, who were also assessed using the Social Role Performance Schedule (SRP) and the ninth edition of the Present State Examination (PSE). All three schedules have been used in previous studies in the...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700025046
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002133
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Several case reports and reviews have suggested an increased incidence of schizophrenia or bipolar disorder among persons with sex chromosome aneuploidies, but this observation may have been caused by biased sampling. METHODS:The 1122 individuals with sex chromosome aneuploidies registered in the Danish Cyt...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003476
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:Despite the demonstrable influence of both genes and the family environment on children's behavioural and emotional development, the mechanisms by which these factors are transmitted from parents to their children are not known. Numerous aspects of the family have long been associated with behavioural and em...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291703008948
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Although symptoms such as fatigue, headache and pain in bones and muscles are common after disasters, risk factors for these symptoms among disaster survivors have rarely been studied. We examined predisposing, precipitating and perpetuating factors for these physical symptoms among survivors of a man-made d...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170700133X
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Little is known about how continuation and maintenance cognitive-behavioural therapy (CBT) influences important psychological constructs that may be associated with long-term outcome of major depressive disorder. The goal of this study was to examine whether CBT would help maintain attributional style change...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291703001028
更新日期:2004-04-01 00:00:00
abstract::A standardized pegboard task was used to investigate changes in manipulative skill as a function of age in 119 right-handed subjects. The typical pattern of cognitive impairment in old age indicates a relative preservation of functions which depend on the integrity of the left hemisphere. In accord with these observat...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700005109
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Oral contraceptive use has been previously associated with an increased risk of suicidal behavior in some, but not all, samples. The use of large, representative, longitudinally-assessed samples may clarify the nature of this potential association. METHODS:We used Swedish national registries to identify wom...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003475
更新日期:2020-10-21 00:00:00
abstract:BACKGROUND:Based on prevalence studies and the few incidence studies of pervasive developmental disorders (PDDs) the prevalence and incidence of these disorders have been claimed to be increasing. METHOD:The annual and age-specific prevalence and incidence rates of childhood autism, atypical autism, Asperger's disorde...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704002387
更新日期:2004-10-01 00:00:00
abstract::One hundred and eighteen subjects with an admission diagnosis of schizophrenia were reassessed after 12 months to establish whether hospital readmission had occurred. All subjects were rated at baseline and after 12 months on the Life Skills Profile (LSP), a 39-item measure of disability, with scores demonstrating mod...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028178
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720001749
更新日期:2020-06-11 00:00:00
abstract:BACKGROUND:Recently released prisoners are at markedly higher risk of suicide than the general population. The aim of this study was to identify key risk factors for suicide by offenders released from prisons in England and Wales. METHOD:All suicides committed by offenders within 12 months of their release from prison...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991048
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Results of previous research examining long-term residual effects of marijuana use on cognition are conflicting. A major methodological limitation of prior studies is the inability to determine whether differences between users and non-users are due to differences in genetic vulnerability preceding drug use ...
journal_title:Psychological medicine
pub_type:
doi:10.1017/s0033291704002260
更新日期:2004-10-01 00:00:00
abstract::The theory that many diseases were produced by focal infection or chronic sepsis enjoyed a brief vogue in general medicine in the first quarter of the twentieth century. This paper explores its practical applications in psychiatry, which extended well into the 1930s. The analysis focuses particularly closely on the ac...
journal_title:Psychological medicine
pub_type: 历史文章,杂志文章,评审
doi:10.1017/s0033291700025824
更新日期:1987-08-01 00:00:00
abstract::From a factor analysis of data from a learning experiment evidence is presented which appears to support the Blomfield-Marr thesis that in the learning of motor actions the cerebellum operates by the turning off of incorrect movements rather than by the turning on of correct ones. The factor model employed is that due...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700018298
更新日期:1976-11-01 00:00:00
abstract:BACKGROUND:Physical symptoms are commonly presented for treatment in the absence of physical pathology. This study tests predictions arising from the theory that childhood sexual abuse leads to emotional distress, illness orientation and social dysfunction as adults and that one or more of these effects, in turn, leads...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798007892
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Discrepancies between population-based estimates of the incidence of psychotic disorder and the treated incidence reported by early psychosis intervention (EPI) programs suggest additional cases may be receiving services elsewhere in the health system. Our objective was to estimate the incidence of non-affec...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718002933
更新日期:2019-09-01 00:00:00
abstract::Levinger & Clarke (1961) found that subjects tended to forget more word associations to emotional rather than neutral words. Kline (1981) regarded this study as providing 'irrefutable evidence for the Freudian concept of repression'. On the other hand, results from Kleinsmith & Kaplan (1964) suggested that this effect...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700017669
更新日期:1990-05-01 00:00:00