Abstract:
:A standardized pegboard task was used to investigate changes in manipulative skill as a function of age in 119 right-handed subjects. The typical pattern of cognitive impairment in old age indicates a relative preservation of functions which depend on the integrity of the left hemisphere. In accord with these observations, we predicted that, with increasing age, right hand motor skills would be better preserved than left hand skills. We found this on initial exposure to the task (P less than 0.01); however, the phenomenon was masked by practice, because older subjects (over 60 years of age) derived more improvement to their left hand motor skill, as a result of practice, than they did to their right hand skill (P less than 0.05). The asymmetrical effects of ageing on motor skill may be relevant to the increasing prevalence of emotional lability and neurosis in the elderly, since emotional control is thought to be dependent on right hemisphere mechanisms.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Weller MP,Latimer-Sayer DTdoi
10.1017/s0033291700005109subject
Has Abstractpub_date
1985-11-01 00:00:00pages
867-72issue
4eissn
0033-2917issn
1469-8978journal_volume
15pub_type
杂志文章abstract:BACKGROUND:Cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) leads to a significant decrease in CFS-related symptoms and disability. The primary objective of this study was to explore whether partners' solicitous responses and patients' and partners' perceived relationship satisfaction had an effect ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000288
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Generalized anxiety disorder (GAD) is highly co-morbid with depression. Depression is associated with elevated levels of the inflammation marker C-reactive protein (CRP), cross-sectionally and over time. To date, no studies have looked at the association between CRP and GAD. METHOD:A total of nine waves of ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000554
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Hierarchical structural models of psychopathology rarely extend to obsessive-compulsive spectrum disorders. The current study sought to examine the higher-order structure of the obsessive-compulsive and related disorders (OCRDs) in DSM-5: obsessive-compulsive disorder (OCD), hoarding disorder (HD), body dysm...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000380
更新日期:2020-03-06 00:00:00
abstract::Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700033171
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:According to the stress sensitization hypothesis, prior exposure to extreme stressors may lead to increased responsiveness to subsequent stressors. It is unclear whether disaster exposure is associated with stress sensitization and, if so, whether this effect is lasting or temporary. This study aimed to inve...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002765
更新日期:2012-08-01 00:00:00
abstract::The authors review the evidence that parental death in childhood predisposes to depressive disorders in later life. The findings in general are quite inconsistent; this is due in part to the methodological limitations of most studies, principally that of inadequate control of potentially confounding variables. Where e...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700044044
更新日期:1980-05-01 00:00:00
abstract:BACKGROUND:Genetic influences on alcoholism risk are well-documented in men, but uncertain in women. We tested for gender differences in genetic influences on, and risk-factors for, DSM-III-R alcohol dependence (AD). METHOD:Diagnostic follow-up interviews were conducted in 1992-3 by telephone with twins from an Austra...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797005643
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO) and recurrence/episodicity. Yet, evidence on whether these subphenotypes are familial or heritable is scarce. The aims of this study are to investigate...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000215
更新日期:2015-07-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719003568
更新日期:2019-12-20 00:00:00
abstract::The variations in suicide mortality in England and Wales over a 100-year period (1876-1975) are explained by the development of a descriptive model. The model used in a stepwise linear regression using 5 variables including toxic gas production. The variables give a good description of the observed changes in suicide ...
journal_title:Psychological medicine
pub_type: 历史文章,杂志文章
doi:10.1017/s003329170005217x
更新日期:1981-05-01 00:00:00
abstract:BACKGROUND:We examined the relationship between childhood sexual abuse (CSA), and interviewees' recollections of pathogenic parenting, testing for possible retrospective biases in the recollections of those who have experienced CSA. METHODS:Information about CSA, parental divorce and interviewees' recollections of par...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002809
更新日期:2000-11-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700014811
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Psychological literature and clinical lore suggest that there may be systematic differences in how various demographic groups experience depressive symptoms, particularly somatic symptoms. The aim of the current study was to use methods based on item response theory (IRT) to examine whether, when equating fo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708003875
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Several case reports and reviews have suggested an increased incidence of schizophrenia or bipolar disorder among persons with sex chromosome aneuploidies, but this observation may have been caused by biased sampling. METHODS:The 1122 individuals with sex chromosome aneuploidies registered in the Danish Cyt...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003476
更新日期:2001-04-01 00:00:00
abstract::Five idiots savants whose artistic output was judged to be at art school entrance standard were matched for performance and verbal IQ with control subjects who had no special artistic talent. Each subject was given tests of reproductive skill with both concrete pictures and unfamiliar and unnameable geometric designs....
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700013003
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:The mechanisms that contribute to emotion dysregulation in anxiety disorders are not well understood. Two common disorders, generalized anxiety disorder (GAD) and panic disorder (PD), were examined to test the hypothesis that both disorders are characterized by hypo-activation in prefrontal cortex (PFC) duri...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712002383
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Stress questionnaires are included in many epidemiological cohort studies but the psychometric characteristics of these questionnaires are largely unknown. The aim of this study was to describe these characteristics for two short questionnaires measuring the lifetime and past year occurrence of stress: the L...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000608
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:The effectiveness of therapeutic interventions in psychosis is increasingly reported in terms of reductions in different symptom dimensions. It remains unclear, however, to what degree such symptomatic changes are accompanied by improvement in other measures such as service use, quality of life, and needs fo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799001014
更新日期:1999-09-01 00:00:00
abstract::The incidence of cavum septum pellucidum (CSP), which has been widely regarded as a developmental anomaly of little clinical importance in neuropathology, was examined in 113 patients with affective disorders (69 with bipolar disorder and 44 with major depression), 40 schizophrenic patients, and 92 control subjects by...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034838
更新日期:1996-03-01 00:00:00
abstract::Forty-eight couples with a presenting problem of female sexual unresponsiveness were treated in a controlled study using a balanced factorial design. The factors varied in this design were medication (testosterone or placebo), treatment frequency (weekly or monthly sessions), and the number of therapists involved (one...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700050091
更新日期:1983-02-01 00:00:00
abstract::In an earlier paper we found that a model of depression developed on a sample of women in a London population was confirmed in a female population in the Outer Hebrides. Differences in the rates of onset and chronic cases between the two populations, however, suggested that the Scottish women might be more likely to b...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700052892
更新日期:1981-08-01 00:00:00
abstract:BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000914
更新日期:2020-04-23 00:00:00
abstract:BACKGROUND:The ability to appreciate humour is essential to successful human interactions. In this study, we hypothesized that individuals with schizophrenia would have diminished ability to recognize and appreciate humour. The relationship between humour experience and clinical symptoms, cognitive and social functioni...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707002528
更新日期:2008-06-01 00:00:00
abstract::One hundred and nineteen primiparae, who were routinely attending ante-natal clinics, were interviewed repeatedly between the 12th and 36th weeks of their pregnancies. The incidence of depression was highest in the first trimester and, overall, about a fifth of the sample was found to be suffering from clinically sign...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700018912
更新日期:1978-11-01 00:00:00
abstract::Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression do not specifically target cognition. Neurocognitive deficits such as memory and concentration problems tend to persist after mood symptoms recover. Improving c...
journal_title:Psychological medicine
pub_type: 社论
doi:10.1017/S0033291716003123
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:The attenuated positive symptoms syndrome (APSS) is considered an at-risk indicator for psychosis. However, the characteristics and developmental aspects of the combined or enriched risk criteria of APSS and basic symptom (BS) criteria, including self-experienced cognitive disturbances (COGDIS) remain under-...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715002627
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Accumulating evidence links blood pressure variability (BPV) with white matter hyperintensities (WMH) and stroke. The longitudinal association between BPV with late onset depression (LOD) and cognitive decline remains unexplored. METHODS:Prospective cohort study of 2812 participant's age ⩾65 years (median a...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002756
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Emotional Stroop tasks have shown attention biases of clinical populations towards stimuli related to their condition. Asperger Syndrome (AS) is a neuropsychiatric condition with social and communication deficits, repetitive behaviours and narrow interests. Social deficits are particularly striking, includin...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706007203
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Exclusion criteria are present in almost all diagnostic categories in both DSM-IV and ICD-10. These exclusion criteria state that one diagnosis is not made if it is 'due to' another disorder. However, there is little empirical evidence demonstrating that the hierarchy imposed by the exclusion criteria is mea...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291702006189
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Depressive disorders are known to often be chronic and recurrent both in the general population and in psychiatric settings. However, despite its importance for public health and services, the outcome of depression in primary care is not well known. METHOD:In The Vantaa Primary Care Depression Study (PC-VDS...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709005182
更新日期:2009-10-01 00:00:00