Neuroanatomical abnormalities in first-episode psychosis across independent samples: a multi-centre mega-analysis.

abstract：BACKGROUND:Expressed emotion (EE) measured from relatives and informal carers has been consistently demonstrated to be associated with clinical outcome in schizophrenic patients. There have also been published studies that have investigated EE in professional carers that have suggested that the quality of the relations...

journal_title：Psychological medicine

authors： Tattan T,Tarrier N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Preparing for potentially threatening events in the future is essential for survival. Anticipating the future to be unpleasant is also a cognitive key feature of depression. We hypothesized that 'pessimism'-related emotion processing would characterize brain activity in major depression.MethodDuring function...

journal_title：Psychological medicine

authors： Herwig U,Brühl AB,Kaffenberger T,Baumgartner T,Boeker H,Jäncke L

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Previous studies have provided initial evidence that people at risk for psychosis (PR) suffer from stigma and discrimination related to their condition. However, no study has systematically reviewed stigma and discrimination associated with being at PR and the potential underlying mechanisms. METHODS:This w...

journal_title：Psychological medicine

authors： Colizzi M,Ruggeri M,Lasalvia A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:High rates of depression associated with childbirth have been reported in many parts of the developing world. However, the prevalence and associations of antenatal and post-natal depression in the rural population remain unknown. Disability associated with depression and its impact on infant health and devel...

journal_title：Psychological medicine

authors： Rahman A,Iqbal Z,Harrington R

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Previous studies on assortment for psychiatric disorders have reported discrepant findings. We aimed to test whether there is a significant association for psychiatric diagnoses, including alcoholism, generalized anxiety disorder, major depressive disorder, panic disorder and phobias between husbands and wiv...

journal_title：Psychological medicine

authors： Maes HH,Neale MC,Kendler KS,Hewitt JK,Silberg JL,Foley DL,Meyer JM,Rutter M,Simonoff E,Pickles A,Eaves LJ

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Attentional difficulties reported in individuals with anorexia nervosa (AN) may be due to preferential processing of disease-salient stimuli at a pre-attentive or at a conscious level or to a general problem in attention. Attentional difficulties may be associated with duration of illness. METHOD:Female par...

journal_title：Psychological medicine

authors： Dickson H,Brooks S,Uher R,Tchanturia K,Treasure J,Campbell IC

更新日期：2008-12-01 00:00:00

abstract：:Two groups of 16 subjects, 8 of each gender, were examined on two occasions, one group before and after restricted environmental stimulation with floatation, and the other group without floatation was the control group. They were examined with a tactile object discrimination task carried out with each hand separately ...

journal_title：Psychological medicine

authors： Raab J,Gruzelier J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The importance of genetic factors in the aetiology of manic-depressive illness (MDI) has been repeatedly confirmed and indicators of vulnerability to the illness in families with affective disorders are needed. Abnormal event-related potentials (ERP) may be markers of genetic vulnerability to mental illness....

journal_title：Psychological medicine

authors： Pierson A,Jouvent R,Quintin P,Perez-Diaz F,Leboyer M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The reasons for high use of primary care, and in particular the role of psychosocial factors, remain unclear. METHODS:We identified and interviewed 236 frequent attenders and 420 normal users, matched by age and sex, of a public Health Centre in Granada, Spain. Users were questioned about mental health (GHQ...

journal_title：Psychological medicine

authors： Bellón JA,Delgado A,Luna JD,Lardelli P

更新日期：1999-11-01 00:00:00

abstract：:Consciousness has evolved and is a feature of all animals with sufficiently complex nervous systems. It is, therefore, primarily a problem for biology, rather than physics. In this review, I will consider three aspects of consciousness: level of consciousness, whether we are awake or in a coma; the contents of conscio...

journal_title：Psychological medicine

authors： Frith CD

更新日期：2019-09-04 00:00:00

abstract：BACKGROUND:The assessment of inter-regional functional connectivity (FC) has allowed for the description of the putative mechanism of action of treatments such as deep brain stimulation (DBS) of the nucleus accumbens in patients with obsessive-compulsive disorder (OCD). Nevertheless, the possible FC alterations of othe...

journal_title：Psychological medicine

authors： Cano M,Alonso P,Martínez-Zalacaín I,Subirà M,Real E,Segalàs C,Pujol J,Cardoner N,Menchón JM,Soriano-Mas C

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The frequency and clinical, neuropsychological and neuroimaging correlates of apathy in patients who have had a stroke are inadequately defined. METHOD:A total of 167 consecutive patients admitted to the stroke units of two university hospitals after an ischaemic stroke and 109 controls received extensive m...

journal_title：Psychological medicine

authors： Brodaty H,Sachdev PS,Withall A,Altendorf A,Valenzuela MJ,Lorentz L

更新日期：2005-12-01 00:00:00

abstract：:In constructing a new self-report questionnaire for measuring self esteem, the aim has been to satisfy psychometric requirements without sacrificing the intuitive meaning of the concept. Self esteem is seen as a composite, and examination of its components may have more analytic or predictive value than 'global' score...

journal_title：Psychological medicine

authors： Robson P

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is a developmental condition that profoundly affects quality of life. Although mounting evidence now suggests uncontrolled mind-wandering as a core aspect of the attentional problems associated with ADHD, the neural mechanisms underpinning this deficit remains ...

journal_title：Psychological medicine

authors： Vatansever D,Bozhilova NS,Asherson P,Smallwood J

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Individuals with depression are often found to perform worse on cognitive tests and to have an increased risk of dementia. The causes and the direction of these associations are however not well understood. We looked at two specific hypotheses, the aetiological risk factor hypothesis and the reverse causalit...

journal_title：Psychological medicine

authors： Jindra C,Li C,Tsang RSM,Bauermeister S,Gallacher J

更新日期：2020-09-11 00:00:00

abstract：BACKGROUND:Prosocial emotions related to self-blame are important in guiding human altruistic decisions. These emotions are elevated in major depressive disorder (MDD), such that MDD has been associated with guilt-driven pathological hyper-altruism. However, the impact of such emotional impairments in MDD on different ...

journal_title：Psychological medicine

authors： Pulcu E,Thomas EJ,Trotter PD,McFarquhar M,Juhasz G,Sahakian BJ,Deakin JF,Anderson IM,Zahn R,Elliott R

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Discontinuation of antipsychotics predisposes patients with remitted/stable first-episode psychosis (FEP) to a higher risk of relapse, but it remains unclear how long discontinuation increases the relapse rate in these patients compared with maintenance. METHODS:This meta-analysis of randomized controlled t...

journal_title：Psychological medicine

authors： Kishi T,Ikuta T,Matsui Y,Inada K,Matsuda Y,Mishima K,Iwata N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:There is substantial variability in the degree of cognitive impairment among older depressed persons. Inconsistencies in previous findings may be due to differences in clinical and demographic characteristics across study samples. We assessed the influence of unipolar depression and severity of depression on...

journal_title：Psychological medicine

authors： Pantzar A,Laukka EJ,Atti AR,Fastbom J,Fratiglioni L,Bäckman L

更新日期：2014-04-01 00:00:00

abstract：INTRODUCTION:Cognitive therapy (CT) for bipolar disorder emphasizes the monitoring and regulation of mood, thoughts and behaviour. The Sense of Hyper-Positive Self Scale (SHPSS) measures the extent to which bipolar patients value themselves and perceive themselves to possess personal attributes (e.g. dynamism, persuasi...

journal_title：Psychological medicine

authors： Lam D,Wright K,Sham P

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period...

journal_title：Psychological medicine

authors： Haukvik UK,Schaer M,Nesvåg R,McNeil T,Hartberg CB,Jönsson EG,Eliez S,Agartz I

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The mechanisms that contribute to emotion dysregulation in anxiety disorders are not well understood. Two common disorders, generalized anxiety disorder (GAD) and panic disorder (PD), were examined to test the hypothesis that both disorders are characterized by hypo-activation in prefrontal cortex (PFC) duri...

journal_title：Psychological medicine

authors： Ball TM,Ramsawh HJ,Campbell-Sills L,Paulus MP,Stein MB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Despite markedly different clinical presentations, few studies have reported differences in neuropsychological functioning between mania and depression. Recent work has suggested that differences may emerge on cognitive tasks requiring affective processing, such as decision-making. The present study sought t...

journal_title：Psychological medicine

authors： Murphy FC,Rubinsztein JS,Michael A,Rogers RD,Robbins TW,Paykel ES,Sahakian BJ

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:This study seeks to clarify the contribution of temporally stable and occasion-specific genetic and environmental influences on risk for major depression (MD). METHOD:Our sample was 2153 members of female-female twin pairs from the Virginia Twin Registry. We examined four personal interview waves conducted ...

journal_title：Psychological medicine

authors： Kendler KS,Gardner CO

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Social capital has been considered aetiologically important in schizophrenia but the empirical evidence to support this hypothesis is absent. We tested whether social capital, measured at the neighbourhood level, was associated with the incidence of schizophrenia (ICD-10 F20). MethodWe administered a cross-s...

journal_title：Psychological medicine

authors： Kirkbride JB,Boydell J,Ploubidis GB,Morgan C,Dazzan P,McKenzie K,Murray RM,Jones PB

更新日期：2008-08-01 00:00:00

abstract：:Using the 40-item Eating Attitudes Test and other self-report questions, a two-stage screening survey of 1020 (F 646, M 374) Chinese bilingual university students in Hong Kong showed that although female students were 'underweight' by Western standard, the majority of them and nearly all female students above a body m...

journal_title：Psychological medicine

authors： Lee S

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:The prevalence and impact of motor coordination difficulties in children with copy number variants associated with neurodevelopmental disorders (ND-CNVs) remains unknown. This study aims to advance understanding of motor coordination difficulties in children with ND-CNVs and establish relationships between i...

journal_title：Psychological medicine

authors： Cunningham AC,Hall J,Owen MJ,van den Bree MBM

更新日期：2019-11-19 00:00:00

abstract：BACKGROUND:In the conditioned fear paradigm, repeated pairing of an aversive unconditioned stimulus (US) (e.g. electric shock) with a neutral conditioned stimulus (CS) (e.g. bright light) results in a conditioned fear response to the light alone. Animal studies have shown that the amygdala plays a critical role in acqu...

journal_title：Psychological medicine

authors： Bremner JD,Vermetten E,Schmahl C,Vaccarino V,Vythilingam M,Afzal N,Grillon C,Charney DS

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Studies suggest that alcohol consumption and alcohol use disorders have distinct genetic backgrounds. METHODS:We examined whether polygenic risk scores (PRS) for consumption and problem subscales of the Alcohol Use Disorders Identification Test (AUDIT-C, AUDIT-P) in the UK Biobank (UKB; N = 121 630) correla...

journal_title：Psychological medicine

authors： Johnson EC,Sanchez-Roige S,Acion L,Adams MJ,Bucholz KK,Chan G,Chao MJ,Chorlian DB,Dick DM,Edenberg HJ,Foroud T,Hayward C,Heron J,Hesselbrock V,Hickman M,Kendler KS,Kinreich S,Kramer J,Kuo SI,Kuperman S,Lai D,McI

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:The association between cigarette smoking and psychosis remains unexplained, but could relate to causal effects in both directions, confounding by socioeconomic factors, such as ethnicity, or use of other substances, including cannabis. Few studies have evaluated the association between cigarettes and psycho...

journal_title：Psychological medicine

authors： Bhavsar V,Jauhar S,Murray RM,Hotopf M,Hatch SL,McNeill A,Boydell J,MacCabe JH

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cigarette smoking is associated with worse cognition and decreased cortical volume and thickness in healthy cohorts. Chronic cigarette smoking is prevalent in schizophrenia spectrum disorders (SSD), but the effects of smoking status on the brain and cognition in SSD are not clear. This study aimed to underst...

journal_title：Psychological medicine

authors： Ringin E,Cropley V,Zalesky A,Bruggemann J,Sundram S,Weickert CS,Weickert TW,Bousman CA,Pantelis C,Van Rheenen TE

更新日期：2021-01-14 00:00:00