To what extent does symptomatic improvement result in better outcome in psychotic illness? UK700 Group.

abstract：BACKGROUND:The World Mental Health Survey Initiative (WMHSI) has advanced our understanding of mental disorders by providing data suitable for analysis across many countries. However, these data have not yet been fully explored from a cross-national lifespan perspective. In particular, there is a shortage of research o...

journal_title：Psychological medicine

authors： McDowell RD,Ryan A,Bunting BP,O'Neill SM,Alonso J,Bruffaerts R,de Graaf R,Florescu S,Vilagut G,de Almeida JM,de Girolamo G,Haro JM,Hinkov H,Kovess-Masfety V,Matschinger H,Tomov T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Studies investigating early developmental factors in relation to psychopathology have mainly focused on schizophrenia. The personality dimension of neuroticism seems to be a general risk factor for psychopathology, but evidence on associations between early developmental precursors and personality traits is ...

journal_title：Psychological medicine

authors： Flensborg-Madsen T,Sørensen HJ,Revsbech R,Mortensen EL

更新日期：2013-06-01 00:00:00

abstract：:Diagnostic communication between doctors and patients is thought to differ radically between Japan and Western countries. To understand diagnostic disclosure to psychiatric patients, a questionnaire with six case vignettes was sent to practising psychiatrists in Japan (N = 166) and North America (N = 112). While over ...

journal_title：Psychological medicine

authors： McDonald-Scott P,Machizawa S,Satoh H

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Although attention deficit hyperactivity disorder (ADHD) and bipolar disorder (BPD) co-occur frequently and represent a particularly morbid clinical form of both disorders, neuroimaging research addressing this co-morbidity is scarce. Our aim was to evaluate the morphometric magnetic resonance imaging (MRI) ...

journal_title：Psychological medicine

authors： Biederman J,Makris N,Valera EM,Monuteaux MC,Goldstein JM,Buka S,Boriel DL,Bandyopadhyay S,Kennedy DN,Caviness VS,Bush G,Aleardi M,Hammerness P,Faraone SV,Seidman LJ

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:As part of a collaborative linkage study, the authors obtained clinical and demographic data on 160 families in which more than one sibling was affected with a bipolar illness. The aim of the study was to identify clinical characteristics that had a high degree of familiality. METHOD:Data on age at onset, g...

journal_title：Psychological medicine

authors： O'Mahony E,Corvin A,O'Connell R,Comerford C,Larsen B,Jones R,McCandless F,Kirov G,Cardno AG,Craddock N,Gill M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:With regard to current neurobiological theories, the aim of our study was to examine possible alterations of temporal and frontal lobe volume in panic disorder (PD). METHOD:Seventeen in-patients with PD and a group of healthy control subjects (HC) matched for age and gender were investigated by quantitative...

journal_title：Psychological medicine

authors： Sobanski T,Wagner G,Peikert G,Gruhn U,Schluttig K,Sauer H,Schlösser R

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Research on the structure of co-morbidity among common mental disorders has largely focused on current prevalence rather than on the development of co-morbidity. This report presents preliminary results of the latter type of analysis based on the US National Comorbidity Survey Replication Adolescent Suppleme...

journal_title：Psychological medicine

authors： Kessler RC,Avenevoli S,McLaughlin KA,Green JG,Lakoma MD,Petukhova M,Pine DS,Sampson NA,Zaslavsky AM,Merikangas KR

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Prior research suggested that time splitting--suppressing the past and dissociating it from present and future--protected refugee mental health in the aftermath of catastrophe. The current study investigates temporal reintegration, defined as cognitive recapture of the past and reconnecting it with present a...

journal_title：Psychological medicine

authors： Beiser M,Wickrama KA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Dissociative reactions in post-traumatic stress disorder (PTSD) have been regarded as strategic responses that limit arousal. Neuroimaging studies suggest distinct prefrontal responses in individuals displaying dissociative and hyperarousal responses to threat in PTSD. Increased prefrontal activity may refle...

journal_title：Psychological medicine

authors： Felmingham K,Kemp AH,Williams L,Falconer E,Olivieri G,Peduto A,Bryant R

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The association between cigarette smoking and psychosis remains unexplained, but could relate to causal effects in both directions, confounding by socioeconomic factors, such as ethnicity, or use of other substances, including cannabis. Few studies have evaluated the association between cigarettes and psycho...

journal_title：Psychological medicine

authors： Bhavsar V,Jauhar S,Murray RM,Hotopf M,Hatch SL,McNeill A,Boydell J,MacCabe JH

更新日期：2018-01-01 00:00:00

abstract：:Consciousness has evolved and is a feature of all animals with sufficiently complex nervous systems. It is, therefore, primarily a problem for biology, rather than physics. In this review, I will consider three aspects of consciousness: level of consciousness, whether we are awake or in a coma; the contents of conscio...

journal_title：Psychological medicine

authors： Frith CD

更新日期：2019-09-04 00:00:00

abstract：BACKGROUND:There is still a relative paucity of information about the long-term course of depression. METHODS:Consecutive patients admitted to a teaching hospital psychiatry unit with symptoms of depression, previously assessed at 6 months and 2, 5 and 15 years after index admission, were reviewed at 25 years (N = 49,...

journal_title：Psychological medicine

authors： Brodaty H,Luscombe G,Peisah C,Anstey K,Andrews G

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study ...

journal_title：Psychological medicine

authors： Andersson E,Enander J,Andrén P,Hedman E,Ljótsson B,Hursti T,Bergström J,Kaldo V,Lindefors N,Andersson G,Rück C

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Complicated grief is a distinct psychological response of individuals facing the loss of a loved one and can lead to many types of adverse health outcomes. Although social support may be beneficial, few studies have examined the beneficial effects of helpful support on complicated grief following bereavement...

journal_title：Psychological medicine

authors： Nam IS

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The development of childhood anxiety disorders (CADs) is likely to depend on pathways that can be programmed by early-life risk factors. We test the hypothesis that early-life maternal factors can predict this programming effect on CAD. METHODS:Data were obtained from 198 women and children from the Mercy P...

journal_title：Psychological medicine

authors： Galbally M,Watson SJ,van Rossum EFC,Chen W,de Kloet ER,Lewis AJ

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Neurocognitive dysfunction in schizophrenia (SZ), bipolar (BD) and related disorders represents a core feature of these illnesses, possibly a marker of underlying pathophysiology. Substantial overlap in domains of neuropsychological deficits has been reported among these disorders after illness onset. Howeve...

journal_title：Psychological medicine

authors： Lewandowski KE,Cohen BM,Ongur D

更新日期：2011-02-01 00:00:00

abstract：:The validity and reliability of an empirically defined fatigue syndrome were tested in a prospective cohort study of 245 primary care patients, with glandular fever or an upper respiratory tract infection. Subjects were interviewed three times in the 6 months after onset. Subjects with the empirically defined fatigue ...

journal_title：Psychological medicine

authors： White PD,Grover SA,Kangro HO,Thomas JM,Amess J,Clare AW

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:There is considerable debate surrounding the effective measurement of DSM-IV symptoms used to assess manic disorders in epidemiological samples. METHOD:Using two nationally representative datasets, the National Epidemiological Survey of Alcohol and Related Conditions (NESARC, n=43,093 at wave 1, n=34,653 at...

journal_title：Psychological medicine

authors： Agrawal A,Nurnberger JI Jr,Lynskey MT

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Interest in the mental health of women deployed to modern military campaigns is increasing, although research examining gender differences is limited. Little is known about experiences women have had on these deployments, or whether men and women respond differently to combat exposure. METHOD:The current st...

journal_title：Psychological medicine

authors： Woodhead C,Wessely S,Jones N,Fear NT,Hatch SL

更新日期：2012-09-01 00:00:00

abstract：:The powerful genome-wide association studies (GWAS) revealed common mutations that increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority were not known to be functional or associated with these illnesses. To help fill this gap, their impact on human brain structure and functio...

journal_title：Psychological medicine

authors： Gurung R,Prata DP

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Seeking compensation has been shown to have an adverse effect on the psychological health and recovery of injured patients, however, this effect requires clarification. METHODS:A total of 2019 adults sustaining a traffic injury were recruited. Of these, 709 (35.1%) lodged a compensation claim. Interviews oc...

journal_title：Psychological medicine

authors： Pozzato I,Kifley A,Craig A,Gopinath B,Tran Y,Jagnoor J,Cameron ID

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Based on the developing clinical and legal literature, and using the framework adopted in draft legislation, capacity to make a valid decision about a clinically required blood test was investigated in three groups of people with a 'mental disability' (i.e. mental illness (chronic schizophrenia), 'learning d...

journal_title：Psychological medicine

authors： Wong JG,Clare CH,Holland AJ,Watson PC,Gunn M

更新日期：2000-03-01 00:00:00

abstract：:A community survey of psychiatric disorder carried out in South London enabled the authors to investigate the 'vulnerability model' proposed by Brown & Harris (1978). In the current study none of the 'vulnerability factors' proposed by Brown & Harris fulfilled the requirements of the model. It was, however, found that...

journal_title：Psychological medicine

authors： Bebbington PE,Sturt E,Tennant C,Hurry J

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Morphometric endophenotypes which have been proposed for psychotic disorders include lateral ventricular enlargement and hippocampal volume reductions. Genetic epidemiological studies support an overlap between schizophrenia and bipolar disorder, and COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes have been implica...

journal_title：Psychological medicine

authors： Dutt A,McDonald C,Dempster E,Prata D,Shaikh M,Williams I,Schulze K,Marshall N,Walshe M,Allin M,Collier D,Murray R,Bramon E

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:High expressed emotion (EE) in families reliably predicts relapse in schizophrenia leading to the assumption that high EE stresses patients and is the cause of relapse. Attempts at validating the stressful properties of high EE using autonomic skin conductance measures have been inconclusive. Since memory lo...

journal_title：Psychological medicine

authors： Dixon MJ,King S,Stip E,Cormier H

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Cigarette smoking is associated with worse cognition and decreased cortical volume and thickness in healthy cohorts. Chronic cigarette smoking is prevalent in schizophrenia spectrum disorders (SSD), but the effects of smoking status on the brain and cognition in SSD are not clear. This study aimed to underst...

journal_title：Psychological medicine

authors： Ringin E,Cropley V,Zalesky A,Bruggemann J,Sundram S,Weickert CS,Weickert TW,Bousman CA,Pantelis C,Van Rheenen TE

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Previous imaging studies have revealed that acute major depression is characterized by altered neural responses to negative emotional stimuli. Typically, responses in limbic regions such as the amygdala are increased while activity in cortical regulatory regions such as the dorsolateral prefrontal cortex (DL...

journal_title：Psychological medicine

authors： Norbury R,Selvaraj S,Taylor MJ,Harmer C,Cowen PJ

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. METHOD:Data were analyzed from the US Nationa...

journal_title：Psychological medicine

authors： Ruscio AM,Lane M,Roy-Byrne P,Stang PE,Stein DJ,Wittchen HU,Kessler RC

更新日期：2005-12-01 00:00:00

abstract：:General practitioners using DSM-III criteria have studied the incidence and prevalence of anorexia nervosa and bulimia nervosa in a large (N = 151,781) representative sample of the Dutch population. The incidence rate for anorexia nervosa is 6.3 and for bulimia nervosa 9.9 per year per 100,000 population. The prevalen...

journal_title：Psychological medicine

authors： Hoek HW

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Although alcohol use disorder (AUD) is associated with future risk for psychosocial dysfunction, the degree to which this arises from a direct causal effect of AUD on functioning v. from correlated risk factors (also known as confounders) is less clearly established. METHOD:AUD was assessed from Swedish med...

journal_title：Psychological medicine

authors： Kendler KS,Ohlsson H,Karriker-Jaffe KJ,Sundquist J,Sundquist K

更新日期：2017-04-01 00:00:00