Sibling pairs with affective disorders: resemblance of demographic and clinical features.

abstract：BACKGROUND:The neurodevelopmental model of psychosis was established over 30 years ago; however, the developmental influence on psychotic symptom expression - how age affects clinical presentation in first-episode psychosis - has not been thoroughly investigated. METHODS:Using generalized additive modeling, which allo...

journal_title：Psychological medicine

authors： Bridgwater M,Bachman P,Tervo-Clemmens B,Haas G,Hayes R,Luna B,Salisbury DF,Jalbrzikowski M

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:The aims of the present study were to examine serum activities of peptidases, i.e. prolyl endopeptidase (PEP) and dipeptidyl peptidase IV (DPP IV), in patients with fibromyalgia and to examine the effects of subchronic treatment with sertraline on these variables. METHOD:Serum PEP and DPP IV activity were m...

journal_title：Psychological medicine

authors： Maes M,Libbrecht I,Van Hunsel F,Lin AH,Bonaccorso S,Goossens F,De Meester I,De Clerck L,Biondi M,Scharpe S,Janca A

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Research on the structure of co-morbidity among common mental disorders has largely focused on current prevalence rather than on the development of co-morbidity. This report presents preliminary results of the latter type of analysis based on the US National Comorbidity Survey Replication Adolescent Suppleme...

journal_title：Psychological medicine

authors： Kessler RC,Avenevoli S,McLaughlin KA,Green JG,Lakoma MD,Petukhova M,Pine DS,Sampson NA,Zaslavsky AM,Merikangas KR

更新日期：2012-09-01 00:00:00

abstract：:The expressed emotion (EE) measure is a robust predictor of relapse in schizophrenia. At least twelve studies from a range of cultures have now shown this, although the authors of one maintain their findings are the result of confounding factors. A thirteenth study which failed to demonstrate a predictive effect was s...

journal_title：Psychological medicine

authors： Kuipers L,Bebbington P

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Chronic fatigue syndrome (CFS) patients often complain that they are more susceptible to acute mental fatigue. It is important to determine whether this is observed using objective tests of sustained attention and responding. METHODS:Sixty-seven patients who fulfilled the criteria for CFS proposed by Sharpe...

journal_title：Psychological medicine

authors： Smith AP,Borysiewicz L,Pollock J,Thomas M,Perry K,Llewelyn M

更新日期：1999-03-01 00:00:00

abstract：:The relationships among symptoms, cognitive functioning and social functioning were investigated in 60 patients with recent-onset schizophrenia. Positive symptoms were unrelated to cognitive measures. Disorganization and depressive symptoms were correlated significantly with Card Sorting performance. Furthermore, only...

journal_title：Psychological medicine

authors： Van der Does AJ,Dingemans PM,Linszen DH,Nugter MA,Scholte WF

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics. ...

journal_title：Psychological medicine

authors： Lowe SR,Ratanatharathorn A,Lai BS,van der Mei W,Barbano AC,Bryant RA,Delahanty DL,Matsuoka YJ,Olff M,Schnyder U,Laska E,Koenen KC,Shalev AY,Kessler RC

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Early Intervention in Psychosis Services (EIS) for young people in England experiencing first-episode psychosis (FEP) were commissioned in 2002, based on an expected incidence of 15 cases per 100 000 person-years, as reported by schizophrenia epidemiology in highly urban settings. Unconfirmed reports from EI...

journal_title：Psychological medicine

authors： Cheng F,Kirkbride JB,Lennox BR,Perez J,Masson K,Lawrence K,Hill K,Feeley L,Painter M,Murray GK,Gallagher O,Bullmore ET,Jones PB

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Depression has been associated with abnormalities in neural underpinnings of Reward Learning (RL). However, inconsistencies have emerged, possibly owing to medication effects. Additionally, it remains unclear how neural RL signals relate to real-life behaviour. The current study, therefore, examined neural R...

journal_title：Psychological medicine

authors： Bakker JM,Goossens L,Kumar P,Lange IMJ,Michielse S,Schruers K,Bastiaansen JA,Lieverse R,Marcelis M,van Amelsvoort T,van Os J,Myin-Germeys I,Pizzagalli DA,Wichers M

更新日期：2019-10-01 00:00:00

abstract：:There have been numerous exhortations for more 'translational research'. A selective review of historical examples of research leading to health benefits is used to consider the various forms of successful interplay between basic science and clinical applications. This is followed by a consideration of key neuroscienc...

journal_title：Psychological medicine

authors： Rutter M,Plomin R

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The World Mental Health Survey Initiative (WMHSI) has advanced our understanding of mental disorders by providing data suitable for analysis across many countries. However, these data have not yet been fully explored from a cross-national lifespan perspective. In particular, there is a shortage of research o...

journal_title：Psychological medicine

authors： McDowell RD,Ryan A,Bunting BP,O'Neill SM,Alonso J,Bruffaerts R,de Graaf R,Florescu S,Vilagut G,de Almeida JM,de Girolamo G,Haro JM,Hinkov H,Kovess-Masfety V,Matschinger H,Tomov T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Maternal depression during pregnancy increases the risk for adverse developmental outcomes in children. However, the underpinning biological mechanisms remain unknown. We tested whether depression was associated with levels of and change in the inflammatory state during pregnancy, if early pregnancy overweig...

journal_title：Psychological medicine

authors： Lahti-Pulkkinen M,Girchenko P,Robinson R,Lehto SM,Toffol E,Heinonen K,Reynolds RM,Kajantie E,Laivuori H,Villa PM,Hämäläinen E,Lahti J,Räikkönen K

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Alterations in self-monitoring have been reported in patients with psychotic disorders, but it remains unclear to what degree they represent true indicators of familial vulnerability for psychosis. METHOD:An error-correction action-monitoring task was used to examine self-monitoring in 42 patients with schi...

journal_title：Psychological medicine

authors： Hommes J,Krabbendam L,Versmissen D,Kircher T,van Os J,van Winkel R

更新日期：2012-02-01 00:00:00

abstract：:The authors review the evidence that parental death in childhood predisposes to depressive disorders in later life. The findings in general are quite inconsistent; this is due in part to the methodological limitations of most studies, principally that of inadequate control of potentially confounding variables. Where e...

journal_title：Psychological medicine

authors： Tennant C,Bebbington P,Hurry J

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:A combined family study and recovered study design was utilized to examine several hypothesized relationships between personality and bulimia nervosa (BN). METHODS:We studied 47 women with a lifetime history of DSM-III-R BN (31 currently ill and 16 recovered), 44 matched control women (CW) with no history o...

journal_title：Psychological medicine

authors： Lilenfeld LR,Stein D,Bulik CM,Strober M,Plotnicov K,Pollice C,Rao R,Merikangas KR,Nagy L,Kaye WH

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...

journal_title：Psychological medicine

authors： Shang CY,Gau SS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:We studied to what extent internet-based cognitive behaviour therapy (CBT) programs for symptoms of depression and anxiety are effective. METHOD:A meta-analysis of 12 randomized controlled trials. RESULTS:The effects of internet-based CBT were compared to control conditions in 13 contrast groups with a tot...

journal_title：Psychological medicine

authors： Spek V,Cuijpers P,Nyklícek I,Riper H,Keyzer J,Pop V

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:In previous studies an association between deployment to Iraq or Afghanistan and an overall increased risk for post-traumatic stress disorder (PTSD) in UK armed forces has not been found. The lack of a deployment effect might be explained by including, in the comparison group, personnel deployed on other ope...

journal_title：Psychological medicine

authors： Jones M,Sundin J,Goodwin L,Hull L,Fear NT,Wessely S,Rona RJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Although the traditional view of bipolar affective disorder is that the majority of patients have full remission between episodes, recent evidence suggests that residual cognitive deficits are present. The aim of this study was to determine whether memory and executive deficits were present in a well-defined...

journal_title：Psychological medicine

authors： Rubinsztein JS,Michael A,Paykel ES,Sahakian BJ

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Affective instability (AI) is poorly defined but considered clinically important. The aim of this study was to examine definitions and measures of AI employed in clinical populations. METHOD:This study was a systematic review using the PRISMA guidelines. MEDLINE, Embase, PsycINFO, PsycArticles and Web of Sc...

journal_title：Psychological medicine

authors： Marwaha S,He Z,Broome M,Singh SP,Scott J,Eyden J,Wolke D

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Agitated patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians differ in opinion and practice. In Lebanon, the use of the triple therapy haloperidol plus promethazine plus chlorpromazine (HPC) is frequently used but no studies involving t...

journal_title：Psychological medicine

authors： Dib JE,Yaacoub HE,Ikdais WH,Atallah E,Merheb TJ,Ajaltouni J,Akkari M,Mourad M,Nasr ME,Hachem D,Kazour F,Tahan F,Haddad G,Azar J,Zoghbi M,Haddad C,Hallit S,Adams CE

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Subjects at 'ultra high risk' (UHR) for developing psychosis have differences in white matter (WM) compared with healthy controls. WM integrity has not yet been investigated in UHR subjects in relation to the development of subsequent psychosis. Hence, we investigated a prospective cohort of UHR subjects com...

journal_title：Psychological medicine

authors： Bloemen OJ,de Koning MB,Schmitz N,Nieman DH,Becker HE,de Haan L,Dingemans P,Linszen DH,van Amelsvoort TA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The importance of genetic factors in the aetiology of manic-depressive illness (MDI) has been repeatedly confirmed and indicators of vulnerability to the illness in families with affective disorders are needed. Abnormal event-related potentials (ERP) may be markers of genetic vulnerability to mental illness....

journal_title：Psychological medicine

authors： Pierson A,Jouvent R,Quintin P,Perez-Diaz F,Leboyer M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Neurocognitive functioning may be impaired in the luteal phase of the menstrual cycle due to associated changes in hypothalamic-pituitary adrenal (HPA) axis function. This study examines the relationship between changes in neurocognition and HPA axis function in different phases of the menstrual cycle. METH...

journal_title：Psychological medicine

authors： Symonds CS,Gallagher P,Thompson JM,Young AH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC...

journal_title：Psychological medicine

authors： Dolan M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Frequency and quantity of alcohol consumption are metrics commonly used to measure alcohol consumption behaviors. Epidemiological studies indicate that these alcohol consumption measures are differentially associated with (mental) health outcomes and socioeconomic status (SES). The current study aims to eluc...

journal_title：Psychological medicine

authors： Marees AT,Smit DJA,Ong JS,MacGregor S,An J,Denys D,Vorspan F,van den Brink W,Derks EM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Previous studies suggest a link between parental separation or divorce and risk of depression in adolescence. There are, however, few studies that have prospectively examined the effects of timing of biological father absence on risk for depressive symptoms in adolescence while controlling for a range of con...

journal_title：Psychological medicine

authors： Culpin I,Heron J,Araya R,Melotti R,Joinson C

更新日期：2013-12-01 00:00:00

abstract：:It is generally recognized that social relationships occupy a central position in psychiatry. To examine the role of social relationships in the onset of minor psychiatric morbidity it is necessary to construct an instrument which will meet the need for a valid, reliable and comprehensive index of social relationships...

journal_title：Psychological medicine

authors： Henderson S,Duncan-Jones P,Byrne DG,Scott R

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Assaultive violence events are associated with increased risk for adverse psychiatric outcomes, including post-traumatic stress (PTS), depression, and generalized anxiety. Prior research has indicated that economic, legal, and social stressors that could follow assaultive events may explain the increased ris...

journal_title：Psychological medicine

authors： Lowe SR,Joshi S,Galea S,Aiello AE,Uddin M,Koenen KC,Cerdá M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Transdiagnostic group cognitive-behavioral therapy (tCBT) is a delivery model that could help overcome barriers to large-scale implementation of evidence-based psychotherapy for anxiety disorders. The aim of this study was to assess the effectiveness of combining group tCBT with treatment-as-usual (TAU), com...

journal_title：Psychological medicine

authors： Roberge P,Provencher MD,Gaboury I,Gosselin P,Vasiliadis HM,Benoît A,Carrier N,Antony MM,Chaillet N,Houle J,Hudon C,Norton PJ

更新日期：2020-12-02 00:00:00