Course and outcome of depressive disorders in primary care: a prospective 18-month study.

abstract：:Between 1968 and 1975 there was a marked, non-artefactual rise in the numbers of young female parasuicides admitted to the Regional Poisoning Treatment Centre in Edinburgh. The greatest increase in rates occurred among girls aged 15--19 (for events, persons and 'first-ever' episodes). Among teenagers the most marked i...

journal_title：Psychological medicine

authors： Kreitman N,Schreiber M

更新日期：1979-08-01 00:00:00

abstract：:A monotonous voice is produced by schizophrenic patients whose expression of emotion is damped down and by patients with a severe degree of depression. Clinically, the distinction between these two diagnostic entities is virtually impossible to establish auditorily on the basis of voice quality alone. The laryngograph...

journal_title：Psychological medicine

authors： Leff J,Abberton E

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for ...

journal_title：Psychological medicine

authors： Madsen IEH,Nyberg ST,Magnusson Hanson LL,Ferrie JE,Ahola K,Alfredsson L,Batty GD,Bjorner JB,Borritz M,Burr H,Chastang JF,de Graaf R,Dragano N,Hamer M,Jokela M,Knutsson A,Koskenvuo M,Koskinen A,Leineweber C,Niedhamme

更新日期：2017-06-01 00:00:00

abstract：:Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neo...

journal_title：Psychological medicine

authors： Brown KW,White T,Palmer D

更新日期：1992-02-01 00:00:00

abstract：:Galvanized with the availability of sophisticated statistical techniques and large datasets, network medicine has emerged as an active area of investigation. Following this trend, network methods have been utilized to understand the interplay between symptoms of mental disorders. This realistic approach that may provi...

journal_title：Psychological medicine

authors： Guloksuz S,Pries LK,van Os J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC...

journal_title：Psychological medicine

authors： Dolan M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:There has been much recent excitement about the possibility that some cases of psychosis may be wholly due to brain-reactive antibodies, with antibodies to N-methyl-D-aspartate receptor (NMDAR) and the voltage-gated potassium channel (VGKC)-complex reported in a few patients with first-episode psychosis (FEP...

journal_title：Psychological medicine

authors： Gaughran F,Lally J,Beck K,McCormack R,Gardner-Sood P,Coutinho E,Jacobson L,Lang B,Sainz-Fuertes R,Papanastasiou E,Di Forti M,Nicholson T,Vincent A,Murray RM

更新日期：2018-06-01 00:00:00

abstract：:This is a study of the criterion validity of a newly developed computerized assessment (PROQSY) of minor psychological morbidity based on the Clinical Interview Schedule, employing a single GP's assessments as criterion measures of such morbidity and Relative Operating Characteristic (ROC) analysis. Two-stage screenin...

journal_title：Psychological medicine

authors： Wilkinson G,Markus AC

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Depressive syndromes not fulfilling the criteria for specified disorders (subthreshold depression, SD) may be clinically important. We aimed to study SD in old and very old age, in comparison with subjects with no depressive symptoms (NDS) and subjects with major depression (MD). METHODS:A community-based r...

journal_title：Psychological medicine

authors： Geiselmann B,Linden M,Helmchen H

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Social disadvantage consistently predicts both self-reported distress and clinically diagnosed disorders such as depression. Yet, many individuals who are exposed to disadvantage do not report high levels of distress. This study extends our recent work showing that high cognitive ability may protect against ...

journal_title：Psychological medicine

authors： Bridger E,Daly M

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Trans and gender diverse (TGD) young people worldwide experience high rates of poor mental health; however, these rates were unknown in Australia. In addition, how negative life events affect the mental health of TGD young people has been largely unexplored. METHODS:This paper reports on novel mental health...

journal_title：Psychological medicine

authors： Strauss P,Cook A,Winter S,Watson V,Wright Toussaint D,Lin A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO) and recurrence/episodicity. Yet, evidence on whether these subphenotypes are familial or heritable is scarce. The aims of this study are to investigate...

journal_title：Psychological medicine

authors： Ferentinos P,Koukounari A,Power R,Rivera M,Uher R,Craddock N,Owen MJ,Korszun A,Jones L,Jones I,Gill M,Rice JP,Ising M,Maier W,Mors O,Rietschel M,Preisig M,Binder EB,Aitchison KJ,Mendlewicz J,Souery D,Hauser J,

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:In schizophrenia, affective disorders, and obsessive-compulsive disorder (OCD) dysfunction of frontal neuronal circuits has been suggested. Such impairments imply corresponding oculomotor deficits. METHOD:Eye movement response to foveofugal and foveopetal step-ramp stimuli was recorded within the same study...

journal_title：Psychological medicine

authors： Lencer R,Trillenberg P,Trillenberg-Krecker K,Junghanns K,Kordon A,Broocks A,Hohagen F,Heide W,Arolt V

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:This study aimed to determine whether depression in patients with long-term conditions is associated with the number of morbidities or the type of co-morbidity. Method A cohort study of 299 912 participants aged 30-100 years. The prevalence of depression, rates of health-care utilization and costs were evalu...

journal_title：Psychological medicine

authors： Bhattarai N,Charlton J,Rudisill C,Gulliford MC

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Both low intelligence and low emotional control have previously been linked to a higher risk of suicide, but it is unknown whether the associations apply consistently over the life course. METHODS:The study was based on data on intelligence and emotional control, collected from 48 738 Swedish men conscripte...

journal_title：Psychological medicine

authors： Hansson Bittár N,Falkstedt D,Sörberg Wallin A

更新日期：2020-10-01 00:00:00

abstract：:Levinger & Clarke (1961) found that subjects tended to forget more word associations to emotional rather than neutral words. Kline (1981) regarded this study as providing 'irrefutable evidence for the Freudian concept of repression'. On the other hand, results from Kleinsmith & Kaplan (1964) suggested that this effect...

journal_title：Psychological medicine

authors： Bradley BP,Baddeley AD

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Mental stress is associated with higher mortality, but it remains controversial whether the association is causal or a consequence of a higher physical disease burden in those with a high mental stress load. Understanding causality is important when developing targeted interventions. We aimed to estimate the...

journal_title：Psychological medicine

authors： Prior A,Fenger-Grøn M,Davydow DS,Olsen J,Li J,Guldin MB,Vestergaard M

更新日期：2018-07-01 00:00:00

abstract：:Messenger RNA (mRNA) is the key intermediate in the gene expression pathway. The amount of mRNA in Alzheimer's disease (AD) brains has been determined using in situ hybridization histochemistry (ISHH) to detect the poly(A) tails of polyadenylated mRNA (poly(A) + mRNA). On a regional basis, AD cases had significantly l...

journal_title：Psychological medicine

authors： Harrison PJ,Barton AJ,Najlerahim A,McDonald B,Pearson RC

更新日期：1991-11-01 00:00:00

abstract：:In a study of domiciliary and out-patient treatment of self-poisoning patients, using a brief problem-orientated approach, it was found that domiciliary treatment resulted in much higher attendance rates but no difference in outcome. Patients who completed out-patient treatment had a better outcome than those who fail...

journal_title：Psychological medicine

authors： Hawton K,Bancroft J,Catalan J,Kingston B,Stedeford A,Welch N

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:To date, magnetic resonance imaging (MRI) has made little impact on the diagnosis and monitoring of psychoses in individual patients. In this study, we used a support vector machine (SVM) whole-brain classification approach to predict future illness course at the individual level from MRI data obtained at th...

journal_title：Psychological medicine

authors： Mourao-Miranda J,Reinders AA,Rocha-Rego V,Lappin J,Rondina J,Morgan C,Morgan KD,Fearon P,Jones PB,Doody GA,Murray RM,Kapur S,Dazzan P

更新日期：2012-05-01 00:00:00

abstract：:This study aimed to investigate the psychological characteristics of chronic fatigue syndrome (CFS: Holmes et al. 1988). A battery of psychometric instruments comprising the General Health Questionnaire (GHQ), the Beck Depression Inventory (BDI), the Minnesota Multiphasic Personality Inventory (MMPI) and the Lazarus W...

journal_title：Psychological medicine

authors： Blakely AA,Howard RC,Sosich RM,Murdoch JC,Menkes DB,Spears GF

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Prior optical coherence tomography (OCT) studies of schizophrenia have identified thinning of retinal layers. However, findings have varied across reports, and most studies have had serious methodological limitations. To address unresolved issues, we determined whether: (1) retinal thinning in schizophrenia ...

journal_title：Psychological medicine

authors： Silverstein SM,Paterno D,Cherneski L,Green S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Seeking compensation has been shown to have an adverse effect on the psychological health and recovery of injured patients, however, this effect requires clarification. METHODS:A total of 2019 adults sustaining a traffic injury were recruited. Of these, 709 (35.1%) lodged a compensation claim. Interviews oc...

journal_title：Psychological medicine

authors： Pozzato I,Kifley A,Craig A,Gopinath B,Tran Y,Jagnoor J,Cameron ID

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Death by suicide is often preceded by attempted suicide, suicidal ideation and non-suicidal self-injury. These extreme thoughts and behaviours have been considered in terms of a continuum of suicidality. Little known research, however, has considered a suicide continuum that extends beyond these extreme thou...

journal_title：Psychological medicine

authors： Butter S,Shevlin M,Murphy J

更新日期：2019-11-01 00:00:00

abstract：:Psychiatric disorders are studied at multiple levels, but there is no agreement on how these levels are related to each other, or how they should be understood in the first place. In this paper, I provide an account of levels and their relationships that is suited for psychopathology, drawing from recent debates in ph...

journal_title：Psychological medicine

authors： Eronen MI

更新日期：2019-09-24 00:00:00

abstract：:Cholecystokinin (CCK) is a peptide originally isolated from the gut. It has been investigated as a candidate treatment for schizophrenia on the assumption that the illness is associated with an imbalance between CCK and dopamine in the mesolimbic dopamine system. Many of the studies to assess the efficacy of CCK used ...

journal_title：Psychological medicine

authors： Montgomery SA,Green MC

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:The development of childhood anxiety disorders (CADs) is likely to depend on pathways that can be programmed by early-life risk factors. We test the hypothesis that early-life maternal factors can predict this programming effect on CAD. METHODS:Data were obtained from 198 women and children from the Mercy P...

journal_title：Psychological medicine

authors： Galbally M,Watson SJ,van Rossum EFC,Chen W,de Kloet ER,Lewis AJ

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Sternberg's Memory Scanning Test (MST) is a useful paradigm for evaluating the speed and efficiency of information processing in working memory. Unfortunately, the classical MST has major drawbacks for use in applied settings such as the clinic. For example, its administration time is long and the test is to...

journal_title：Psychological medicine

authors： Van Der Elst W,Van Boxtel MP,Van Breukelen GJ,Jolles J

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Generalized anxiety disorder is a common condition of excessive worry and tension which tends to run a chronic course associated with significant psychiatric and medical problems. Cognitive behaviour therapy (CBT) has been shown to be of clinical value in about 50% of cases with treatment gains maintained ov...

journal_title：Psychological medicine

authors： Durham RC,Chambers JA,MacDonald RR,Power KG,Major K

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...

journal_title：Psychological medicine

authors： Goodwin RD,Brook JS,Cohen P

更新日期：2005-02-01 00:00:00