Abstract:
BACKGROUND:Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC) and VMPFC function. METHOD:Ninety-six male offenders with ASPD who were assessed using the psychopathy checklist: screening version (PCL:SV) and 49 male right-handed healthy controls (HCs), matched for age and IQ, completed a neuropsychological test battery. RESULTS:Offenders with ASPD displayed subtle impairments on executive function tasks of planning ability and set shifting and behavioural inhibition compared to HCs. However, among the offenders with ASPD there was no significant association between executive function impairment and scores on the measure of psychopathy. CONCLUSIONS:Psychopathic traits in offenders with ASPD are not associated with greater executive function impairment.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Dolan Mdoi
10.1017/S0033291711002686subject
Has Abstractpub_date
2012-08-01 00:00:00pages
1715-25issue
8eissn
0033-2917issn
1469-8978pii
S0033291711002686journal_volume
42pub_type
杂志文章abstract:BACKGROUND:Childhood trauma is a risk factor for psychosis. Deficits in response inhibition are common to psychosis and trauma-exposed populations, and associated brain functions may be affected by trauma exposure in psychotic disorders. We aimed to identify the influence of trauma-exposure on brain activation and func...
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